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Volumn 184, Issue 8, 2014, Pages 2355-2364

MiR-185 inhibits hepatocellular carcinoma growth by targeting the DNMT1/PTEN/Akt pathway

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE 1; MICRORNA; MICRORNA 185; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; MIRN185 MICRORNA, HUMAN; PTEN PROTEIN, HUMAN;

EID: 84904618392     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2014.05.004     Document Type: Article
Times cited : (90)

References (38)
  • 1
    • 33747830764 scopus 로고    scopus 로고
    • Hepatocellular carcinoma pathogenesis: From genes to environment
    • P.A. Farazi, and R.A. DePinho Hepatocellular carcinoma pathogenesis: from genes to environment Nat Rev Cancer 6 2006 674 687
    • (2006) Nat Rev Cancer , vol.6 , pp. 674-687
    • Farazi, P.A.1    Depinho, R.A.2
  • 2
    • 33745521748 scopus 로고    scopus 로고
    • Epidemiology of hepatocellular carcinoma in areas of low hepatitis B and hepatitis C endemicity
    • L.B. Seeff, and J.H. Hoofnagle Epidemiology of hepatocellular carcinoma in areas of low hepatitis B and hepatitis C endemicity Oncogene 25 2006 3771 3777
    • (2006) Oncogene , vol.25 , pp. 3771-3777
    • Seeff, L.B.1    Hoofnagle, J.H.2
  • 3
    • 80053088189 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • H.B. El-Serag Hepatocellular carcinoma N Engl J Med 365 2011 1118 1127
    • (2011) N Engl J Med , vol.365 , pp. 1118-1127
    • El-Serag, H.B.1
  • 4
    • 54449083925 scopus 로고    scopus 로고
    • Molecular targeted therapies in hepatocellular carcinoma
    • J.M. Llovet, and J. Bruix Molecular targeted therapies in hepatocellular carcinoma Hepatology 48 2008 1312 1327
    • (2008) Hepatology , vol.48 , pp. 1312-1327
    • Llovet, J.M.1    Bruix, J.2
  • 5
    • 63049133092 scopus 로고    scopus 로고
    • Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005
    • S.F. Altekruse, K.A. McGlynn, and M.E. Reichman Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005 J Clin Oncol 27 2009 1485 1491
    • (2009) J Clin Oncol , vol.27 , pp. 1485-1491
    • Altekruse, S.F.1    McGlynn, K.A.2    Reichman, M.E.3
  • 6
    • 84859212951 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • A. Forner, J.M. Llovet, and J. Bruix Hepatocellular carcinoma Lancet 379 2012 1245 1255
    • (2012) Lancet , vol.379 , pp. 1245-1255
    • Forner, A.1    Llovet, J.M.2    Bruix, J.3
  • 8
    • 79955433548 scopus 로고    scopus 로고
    • Targeted therapies for hepatocellular carcinoma
    • A. Villanueva, and J.M. Llovet Targeted therapies for hepatocellular carcinoma Gastroenterology 140 2011 1410 1426
    • (2011) Gastroenterology , vol.140 , pp. 1410-1426
    • Villanueva, A.1    Llovet, J.M.2
  • 9
    • 33644768174 scopus 로고    scopus 로고
    • Control of translation and mRNA degradation by miRNAs and siRNAs
    • M.A. Valencia-Sanchez, J. Liu, G.J. Hannon, and R. Parker Control of translation and mRNA degradation by miRNAs and siRNAs Genes Dev 20 2006 515 524
    • (2006) Genes Dev , vol.20 , pp. 515-524
    • Valencia-Sanchez, M.A.1    Liu, J.2    Hannon, G.J.3    Parker, R.4
  • 10
  • 11
    • 58149376548 scopus 로고    scopus 로고
    • Molecular mechanisms of hepatocellular carcinoma
    • R.N. Aravalli, C.J. Steer, and E.N. Cressman Molecular mechanisms of hepatocellular carcinoma Hepatology 48 2008 2047 2063
    • (2008) Hepatology , vol.48 , pp. 2047-2063
    • Aravalli, R.N.1    Steer, C.J.2    Cressman, E.N.3
  • 12
    • 84873296666 scopus 로고    scopus 로고
    • MicroRNAs: New tools for diagnosis, prognosis, and therapy in hepatocellular carcinoma?
    • S. Giordano, and A. Columbano MicroRNAs: new tools for diagnosis, prognosis, and therapy in hepatocellular carcinoma? Hepatology 57 2013 840 847
    • (2013) Hepatology , vol.57 , pp. 840-847
    • Giordano, S.1    Columbano, A.2
  • 13
    • 84861195622 scopus 로고    scopus 로고
    • Diagnostic and therapeutic potential of miRNA signatures in patients with hepatocellular carcinoma
    • F. Borel, P. Konstantinova, and P.L. Jansen Diagnostic and therapeutic potential of miRNA signatures in patients with hepatocellular carcinoma J Hepatol 56 2012 1371 1383
    • (2012) J Hepatol , vol.56 , pp. 1371-1383
    • Borel, F.1    Konstantinova, P.2    Jansen, P.L.3
  • 14
    • 80053309537 scopus 로고    scopus 로고
    • Intercellular nanovesicle-mediated microRNA transfer: A mechanism of environmental modulation of hepatocellular cancer cell growth
    • T. Kogure, W.L. Lin, I.K. Yan, C. Braconi, and T. Patel Intercellular nanovesicle-mediated microRNA transfer: a mechanism of environmental modulation of hepatocellular cancer cell growth Hepatology 54 2011 1237 1248
    • (2011) Hepatology , vol.54 , pp. 1237-1248
    • Kogure, T.1    Lin, W.L.2    Yan, I.K.3    Braconi, C.4    Patel, T.5
  • 16
    • 84863983719 scopus 로고    scopus 로고
    • MicroRNA silencing and the development of novel therapies for liver disease
    • G. Szabo, P. Sarnow, and S. Bala MicroRNA silencing and the development of novel therapies for liver disease J Hepatol 57 2012 462 466
    • (2012) J Hepatol , vol.57 , pp. 462-466
    • Szabo, G.1    Sarnow, P.2    Bala, S.3
  • 18
    • 84878354625 scopus 로고    scopus 로고
    • Metastasis-related miR-185 is a potential prognostic biomarker for hepatocellular carcinoma in early stage
    • Q. Zhi, J. Zhu, X. Guo, S. He, X. Xue, J. Zhou, B. Hu, H. Li, S. Chen, H. Zhao, and Y. Kuang Metastasis-related miR-185 is a potential prognostic biomarker for hepatocellular carcinoma in early stage Biomed Pharmacother 67 2013 393 398
    • (2013) Biomed Pharmacother , vol.67 , pp. 393-398
    • Zhi, Q.1    Zhu, J.2    Guo, X.3    He, S.4    Xue, X.5    Zhou, J.6    Hu, B.7    Li, H.8    Chen, S.9    Zhao, H.10    Kuang, Y.11
  • 20
    • 33847293264 scopus 로고    scopus 로고
    • Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells
    • T. Chen, S. Hevi, F. Gay, N. Tsujimoto, T. He, B. Zhang, Y. Ueda, and E. Li Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells Nat Genet 39 2007 391 396
    • (2007) Nat Genet , vol.39 , pp. 391-396
    • Chen, T.1    Hevi, S.2    Gay, F.3    Tsujimoto, N.4    He, T.5    Zhang, B.6    Ueda, Y.7    Li, E.8
  • 21
  • 22
    • 77951460399 scopus 로고    scopus 로고
    • Epigenetic regulation of cancer stem cell marker CD133 by transforming growth factor-beta
    • H. You, W. Ding, and C.B. Rountree Epigenetic regulation of cancer stem cell marker CD133 by transforming growth factor-beta Hepatology 51 2010 1635 1644
    • (2010) Hepatology , vol.51 , pp. 1635-1644
    • You, H.1    Ding, W.2    Rountree, C.B.3
  • 25
    • 77952575909 scopus 로고    scopus 로고
    • PTEN in non-alcoholic fatty liver disease/non-alcoholic steatohepatitis and cancer
    • M. Peyrou, L. Bourgoin, and M. Foti PTEN in non-alcoholic fatty liver disease/non-alcoholic steatohepatitis and cancer Dig Dis 28 2010 236 246
    • (2010) Dig Dis , vol.28 , pp. 236-246
    • Peyrou, M.1    Bourgoin, L.2    Foti, M.3
  • 26
    • 79955110863 scopus 로고    scopus 로고
    • Loss of phosphatase and tensin homolog enhances cell invasion and migration through AKT/Sp-1 transcription factor/matrix metalloproteinase 2 activation in hepatocellular carcinoma and has clinicopathologic significance
    • K.M. Sze, K.L. Wong, G.K. Chu, J.M. Lee, T.O. Yau, and I.O. Ng Loss of phosphatase and tensin homolog enhances cell invasion and migration through AKT/Sp-1 transcription factor/matrix metalloproteinase 2 activation in hepatocellular carcinoma and has clinicopathologic significance Hepatology 53 2011 1558 1569
    • (2011) Hepatology , vol.53 , pp. 1558-1569
    • Sze, K.M.1    Wong, K.L.2    Chu, G.K.3    Lee, J.M.4    Yau, T.O.5    Ng, I.O.6
  • 27
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • F. Meng, R. Henson, H. Wehbe-Janek, K. Ghoshal, S.T. Jacob, and T. Patel MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer Gastroenterology 133 2007 647 658
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5    Patel, T.6
  • 28
    • 77951722798 scopus 로고    scopus 로고
    • PTEN inhibits the migration and invasion of HepG2 cells by coordinately decreasing MMP expression via the PI3K/Akt pathway
    • T. Tian, K.J. Nan, H. Guo, W.J. Wang, Z.P. Ruan, S.H. Wang, X. Liang, and C.X. Lu PTEN inhibits the migration and invasion of HepG2 cells by coordinately decreasing MMP expression via the PI3K/Akt pathway Oncol Rep 23 2010 1593 1600
    • (2010) Oncol Rep , vol.23 , pp. 1593-1600
    • Tian, T.1    Nan, K.J.2    Guo, H.3    Wang, W.J.4    Ruan, Z.P.5    Wang, S.H.6    Liang, X.7    Lu, C.X.8
  • 30
    • 33645214725 scopus 로고    scopus 로고
    • Review of genetic and epigenetic alterations in hepatocarcinogenesis
    • N.I. Herath, B.A. Leggett, and G.A. MacDonald Review of genetic and epigenetic alterations in hepatocarcinogenesis J Gastroenterol Hepatol 21 2006 15 21
    • (2006) J Gastroenterol Hepatol , vol.21 , pp. 15-21
    • Herath, N.I.1    Leggett, B.A.2    Macdonald, G.A.3
  • 31
    • 78649327715 scopus 로고    scopus 로고
    • Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation
    • G.L. Gravina, C. Festuccia, F. Marampon, V.M. Popov, R.G. Pestell, B.M. Zani, and V. Tombolini Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation Mol Cancer 9 2010 305
    • (2010) Mol Cancer , vol.9 , pp. 305
    • Gravina, G.L.1    Festuccia, C.2    Marampon, F.3    Popov, V.M.4    Pestell, R.G.5    Zani, B.M.6    Tombolini, V.7
  • 32
    • 77958150580 scopus 로고    scopus 로고
    • Targeting DNA methylation for epigenetic therapy
    • X. Yang, F. Lay, H. Han, and P.A. Jones Targeting DNA methylation for epigenetic therapy Trends Pharmacol Sci 31 2010 536 546
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 536-546
    • Yang, X.1    Lay, F.2    Han, H.3    Jones, P.A.4
  • 33
    • 36949016699 scopus 로고    scopus 로고
    • Alterations of DNA methylation associated with abnormalities of DNA methyltransferases in human cancers during transition from a precancerous to a malignant state
    • Y. Kanai, and S. Hirohashi Alterations of DNA methylation associated with abnormalities of DNA methyltransferases in human cancers during transition from a precancerous to a malignant state Carcinogenesis 28 2007 2434 2442
    • (2007) Carcinogenesis , vol.28 , pp. 2434-2442
    • Kanai, Y.1    Hirohashi, S.2
  • 34
    • 79956330964 scopus 로고    scopus 로고
    • CpG islands and the regulation of transcription
    • A.M. Deaton, and A. Bird CpG islands and the regulation of transcription Genes Dev 25 2011 1010 1022
    • (2011) Genes Dev , vol.25 , pp. 1010-1022
    • Deaton, A.M.1    Bird, A.2
  • 36
    • 3042707323 scopus 로고    scopus 로고
    • Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis
    • J. Yu, M. Ni, J. Xu, H. Zhang, B. Gao, J. Gu, J. Chen, L. Zhang, M. Wu, S. Zhen, and J. Zhu Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis BMC Cancer 2 2002 29
    • (2002) BMC Cancer , vol.2 , pp. 29
    • Yu, J.1    Ni, M.2    Xu, J.3    Zhang, H.4    Gao, B.5    Gu, J.6    Chen, J.7    Zhang, L.8    Wu, M.9    Zhen, S.10    Zhu, J.11
  • 37
    • 78149478781 scopus 로고    scopus 로고
    • Aberrant epigenetic landscape in cancer: How cellular identity goes awry
    • M. Berdasco, and M. Esteller Aberrant epigenetic landscape in cancer: how cellular identity goes awry Dev Cell 19 2010 698 711
    • (2010) Dev Cell , vol.19 , pp. 698-711
    • Berdasco, M.1    Esteller, M.2
  • 38
    • 77957355926 scopus 로고    scopus 로고
    • Epigenetics and miRNAs in human cancer
    • M. Fabbri, and G.A. Calin Epigenetics and miRNAs in human cancer Adv Genet 70 2010 87 99
    • (2010) Adv Genet , vol.70 , pp. 87-99
    • Fabbri, M.1    Calin, G.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.