Mechanism underlying unaltered cortical inhibitory synaptic transmission in contrast with enhanced excitatory transmission in CaV2.1 knockin migraine mice

Neurobiology of Disease

Volumn 69, Issue , 2014, Pages 225-234

  Vecchia, Dania ^a   Tottene, Angelita ^a   van den Maagdenberg, Arn M J M ^b   Pietrobon, Daniela ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Channelopathy; Excitatory inhibitory balance; Fast spiking interneuron; Knockin mouse model; Migraine

Indexed keywords

CALCIUM CHANNEL CAV 2.1; CALCIUM ION; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; 4 AMINOBUTYRIC ACID; CACNA1A PROTEIN, HUMAN; CALCIUM; CALCIUM CHANNEL; CALCIUM CHANNEL N TYPE; VOLTAGE-DEPENDENT CALCIUM CHANNEL (P-Q TYPE);

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; EVOKED RESPONSE; EXTRACELLULAR CALCIUM; FAMILIAL HEMIPLEGIC MIGRAINE; FAMILIAL HEMIPLEGIC MIGRAINE TYPE 1; INTERNEURON; INTRACELLULAR RECORDING; MIGRAINE WITH AURA; MOUSE; MUTATIONAL ANALYSIS; NERVE CELL STIMULATION; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; SPIKE WAVE; SYNAPTIC INHIBITION; ACTION POTENTIAL; ANIMAL; BRAIN CORTEX; C57BL MOUSE; CULTURE TECHNIQUE; DISEASE MODEL; DRUG EFFECTS; GENE TARGETING; GENETICS; HUMAN; INHIBITORY POSTSYNAPTIC POTENTIAL; METABOLISM; MUTATION; NERVE CELL INHIBITION; PATHOPHYSIOLOGY; PHYSIOLOGY; SYNAPTIC TRANSMISSION; SYNAPTOSOME; TRANSGENIC MOUSE;

ACTION POTENTIALS; ANIMALS; CALCIUM; CALCIUM CHANNELS; CALCIUM CHANNELS, N-TYPE; CELL CULTURE TECHNIQUES; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; GAMMA-AMINOBUTYRIC ACID; GENE KNOCK-IN TECHNIQUES; HUMANS; INHIBITORY POSTSYNAPTIC POTENTIALS; INTERNEURONS; MICE, INBRED C57BL; MICE, TRANSGENIC; MIGRAINE WITH AURA; MUTATION; NEURAL INHIBITION; PRESYNAPTIC TERMINALS; PYRAMIDAL CELLS; SYNAPTIC TRANSMISSION;

EID: 84904603215     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2014.05.035     Document Type: Article

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