Novel BCR-ABL1 fusion identified by targeted next-generation sequencing in a patient with an atypical myeloproliferative neoplasm

Human Pathology

Volumn 45, Issue 8, 2014, Pages 1784-1789

  Frederick, Lori ^a   Beardell, Frank ^b   Viswanatha, David S ^a  

^a MAYO CLINIC   (United States)

^b Delaware Clinical and Laboratory Physicians   (United States)

Author keywords

BCR ABL1; Chronic myeloid leukemia; Myeloproliferative neoplasm; Next generation sequencing

Indexed keywords

ARGININOSUCCINATE SYNTHASE; BCR ABL1 FUSION PROTEIN; COMPLEMENTARY DNA; DASATINIB; HYBRID PROTEIN; NILOTINIB; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ADULT; ARTICLE; BONE MARROW BIOPSY; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER REGRESSION; CASE REPORT; CELL HYPERPLASIA; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; DNA FRAGMENTATION; DNA SPLICING; EXON; FATIGUE; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLOW UP; FUSION GENE; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC VARIABILITY; HUMAN; HUMAN TISSUE; INTRON; KARYOTYPE 46,XY; LEUKOCYTOSIS; MALE; MEGALOCYTOSIS; MIDDLE AGED; MOLECULAR DIAGNOSIS; MONOSOMY 7; MYELOPROLIFERATIVE NEOPLASM; NEUTROPHIL; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLENOMEGALY; THROMBOCYTOSIS; TREATMENT DURATION; TRISOMY 8;

BCR-ABL1; CHRONIC MYELOID LEUKEMIA; MYELOPROLIFERATIVE NEOPLASM; NEXT-GENERATION SEQUENCING;

FUSION PROTEINS, BCR-ABL; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MALE; MIDDLE AGED;

EID: 84904581830     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2014.04.017     Document Type: Article

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