-
1
-
-
78649712445
-
The continuing crisis in antibiotic resistance
-
French GL (2010) The continuing crisis in antibiotic resistance. Int J Antimicrob Agents 36 Suppl 3: S3-7.
-
(2010)
Int J Antimicrob Agents
, vol.36
, Issue.SUPPL. 3
-
-
French, G.L.1
-
2
-
-
56849091862
-
Antimicrobial resistance in Europe and its potential impact on empirical therapy
-
DOI 10.1111/j.1469-0691.2008.02126.x, Selecting empiric antibiotic therapy in an era of multi-drug resistance - is the cupboard really bare
-
Rossolini GM, Mantengoli E (2008) Antimicrobial resistance in Europe and its potential impact on empirical therapy. Clin Microbiol Infect 14 Suppl 6: 2-8. (Pubitemid 352749376)
-
(2008)
Clinical Microbiology and Infection
, vol.14
, Issue.SUPPL. 6
, pp. 2-8
-
-
Rossolini, G.M.1
Mantengoli, E.2
-
3
-
-
84883076264
-
Severe sepsis and septic shock
-
Angus DC, van der Poll T (2013) Severe sepsis and septic shock. N Engl J Med 369: 840-851.
-
(2013)
N Engl J Med
, vol.369
, pp. 840-851
-
-
Angus, D.C.1
Van Der Poll, T.2
-
4
-
-
72249087115
-
International study of the prevalence and outcomes of infection in intensive care units
-
Vincent JL, Rello J, Marshall J, Silva E, Anzueto A, et al. (2009) International study of the prevalence and outcomes of infection in intensive care units. JAMA 302: 2323-2329.
-
(2009)
JAMA
, vol.302
, pp. 2323-2329
-
-
Vincent, J.L.1
Rello, J.2
Marshall, J.3
Silva, E.4
Anzueto, A.5
-
5
-
-
31344461826
-
Sepsis in European intensive care units: Results of the SOAP study
-
DOI 10.1097/01.CCM.0000194725.48928.3A
-
Vincent JL, Sakr Y, Sprung CL, Ranieri VM, Reinhart K, et al. (2006) Sepsis in European intensive care units: results of the SOAP study. Crit Care Med 34: 344-353. (Pubitemid 43145611)
-
(2006)
Critical Care Medicine
, vol.34
, Issue.2
, pp. 344-353
-
-
Vincent, J.-L.1
Sakr, Y.2
Sprung, C.L.3
Ranieri, V.M.4
Reinhart, K.5
Gerlach, H.6
Moreno, R.7
Carlet, J.8
Le, G.J.-R.9
Payen, D.10
-
6
-
-
0037451929
-
The epidemiology of sepsis in the United States from 1979 through 2000
-
DOI 10.1056/NEJMoa022139
-
Martin GS, Mannino DM, Eaton S, Moss M (2003) The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 348: 1546-1554. (Pubitemid 36437931)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.16
, pp. 1546-1554
-
-
Martin, G.S.1
Mannino, D.M.2
Eaton, S.3
Moss, M.4
-
7
-
-
84879072604
-
Proteolytic activation transforms heparin cofactor II into a host defense molecule
-
Kalle M, Papareddy P, Kasetty G, Tollefsen DM, Malmsten M, et al. (2013) Proteolytic activation transforms heparin cofactor II into a host defense molecule. J Immunol 190: 6303-6310.
-
(2013)
J Immunol
, vol.190
, pp. 6303-6310
-
-
Kalle, M.1
Papareddy, P.2
Kasetty, G.3
Tollefsen, D.M.4
Malmsten, M.5
-
9
-
-
31344451275
-
High-dose antithrombin III in the treatment of severe sepsis in patients with a high risk of death: Efficacy and safety
-
DOI 10.1097/01.CCM.0000194731.08896.99
-
Wiedermann CJ, Hoffmann JN, Juers M, Ostermann H, Kienast J, et al. (2006) High-dose antithrombin III in the treatment of severe sepsis in patients with a high risk of death: efficacy and safety. Crit Care Med 34: 285-292. (Pubitemid 43145602)
-
(2006)
Critical Care Medicine
, vol.34
, Issue.2
, pp. 285-292
-
-
Wiedermann, C.J.1
Hoffmann, J.N.2
Juers, M.3
Ostermann, H.4
Kienast, J.5
Briegel, J.6
Strauss, R.7
Keinecke, H.-O.8
Warren, B.L.9
Opal, S.M.10
-
10
-
-
0038690407
-
Efficacy and Safety of Tifacogin (Recombinant Tissue Factor Pathway Inhibitor) in Severe Sepsis: A Randomized Controlled Trial
-
DOI 10.1001/jama.290.2.238
-
Abraham E, Reinhart K, Opal S, Demeyer I, Doig C, et al. (2003) Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial. JAMA 290: 238-247. (Pubitemid 37430063)
-
(2003)
Journal of the American Medical Association
, vol.290
, Issue.2
, pp. 238-247
-
-
Abraham, E.1
Reinhart, K.2
Opal, S.3
Demeyer, I.4
Doig, C.5
Lopez, R.A.6
Beale, R.7
Svoboda, P.8
Laterre, P.F.9
Simon, S.10
Light, B.11
Spapen, H.12
Stone, J.13
Seibert, A.14
Peckelsen, C.15
De Deyne, C.16
Postier, R.17
Pettila, V.18
Sprung, C.L.19
Artigas, A.20
Percell, S.R.21
Shu, V.22
Zwingelstein, C.23
Tobias, J.24
Poole, L.25
Stolzenbach, J.C.26
Creasey, A.A.27
more..
-
11
-
-
63149094677
-
A clinical evaluation committee assessment of recombinant human tissue factor pathway inhibitor (tifacogin) in patients with severe community-acquired pneumonia
-
Laterre PF, Opal SM, Abraham E, LaRosa SP, Creasey AA, et al. (2009) A clinical evaluation committee assessment of recombinant human tissue factor pathway inhibitor (tifacogin) in patients with severe community-acquired pneumonia. Crit Care 13: R36.
-
(2009)
Crit Care
, vol.13
-
-
Laterre, P.F.1
Opal, S.M.2
Abraham, E.3
LaRosa, S.P.4
Creasey, A.A.5
-
12
-
-
78650936443
-
Recombinant human tissue factor pathway inhibitor exerts anticoagulant, anti-inflammatory and antimicrobial effects in murine pneumococcal pneumonia
-
Van Den Boogaard FE, Brands X, Schultz MJ, Levi M, Roelofs JJ, et al. (2011) Recombinant human tissue factor pathway inhibitor exerts anticoagulant, anti-inflammatory and antimicrobial effects in murine pneumococcal pneumonia. J Thromb Haemost 9: 122-132.
-
(2011)
J Thromb Haemost
, vol.9
, pp. 122-132
-
-
Van Den Boogaard, F.E.1
Brands, X.2
Schultz, M.J.3
Levi, M.4
Roelofs, J.J.5
-
14
-
-
0035159740
-
Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: A multicenter, randomized, placebo-controlled, single-blind, dose escalation study
-
Abraham E, Reinhart K, Svoboda P, Seibert A, Olthoff D, et al. (2001) Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: a multicenter, randomized, placebo-controlled, single-blind, dose escalation study. Crit Care Med 29: 2081-2089. (Pubitemid 33063534)
-
(2001)
Critical Care Medicine
, vol.29
, Issue.11
, pp. 2081-2089
-
-
Abraham, E.1
Reinhart, K.2
Svoboda, P.3
Seibert, A.4
Olthoff, D.5
Dal, N.A.6
Postier, R.7
Hempelmann, G.8
Butler, T.9
Martin, E.10
Zwingelstein, C.11
Percell, S.12
Shu, V.13
Leighton, A.14
Creasey, A.A.15
-
15
-
-
33845699790
-
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies
-
DOI 10.1038/nbt1267, PII NBT1267
-
Hancock RE, Sahl HG (2006) Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nat Biotechnol 24: 1551-1557. (Pubitemid 44967479)
-
(2006)
Nature Biotechnology
, vol.24
, Issue.12
, pp. 1551-1557
-
-
Hancock, R.E.W.1
Sahl, H.-G.2
-
16
-
-
84877318780
-
Antimicrobial peptides stage a comeback
-
Fox JL (2013) Antimicrobial peptides stage a comeback. Nat Biotechnol 31: 379-382.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 379-382
-
-
Fox, J.L.1
-
17
-
-
84860601877
-
Antimicrobial peptides: Key components of the innate immune system
-
Pasupuleti M, Schmidtchen A, Malmsten M (2012) Antimicrobial peptides: key components of the innate immune system. Crit Rev Biotechnol 32: 143-171.
-
(2012)
Crit Rev Biotechnol
, vol.32
, pp. 143-171
-
-
Pasupuleti, M.1
Schmidtchen, A.2
Malmsten, M.3
-
18
-
-
61349169039
-
AMPed up immunity: How antimicrobial peptides have multiple roles in immune defense
-
Lai Y, Gallo RL (2009) AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense. Trends Immunol 30: 131-141.
-
(2009)
Trends Immunol
, vol.30
, pp. 131-141
-
-
Lai, Y.1
Gallo, R.L.2
-
19
-
-
37849008715
-
Human antimicrobial proteins effectors of innate immunity
-
Harder J, Glaser R, Schroder JM (2007) Human antimicrobial proteins effectors of innate immunity. J Endotoxin Res 13: 317-338.
-
(2007)
J Endotoxin Res
, vol.13
, pp. 317-338
-
-
Harder, J.1
Glaser, R.2
Schroder, J.M.3
-
20
-
-
0037165196
-
Antimicrobial peptides of multicellular organisms
-
Zasloff M (2002) Antimicrobial peptides of multicellular organisms. Nature 415: 389-395.
-
(2002)
Nature
, vol.415
, pp. 389-395
-
-
Zasloff, M.1
-
21
-
-
0033864862
-
Amphipathic, alpha-helical antimicrobial peptides
-
Tossi A, Sandri L, Giangaspero A (2000) Amphipathic, alpha-helical antimicrobial peptides. Biopolymers 55: 4-30.
-
(2000)
Biopolymers
, vol.55
, pp. 4-30
-
-
Tossi, A.1
Sandri, L.2
Giangaspero, A.3
-
23
-
-
77951908013
-
Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment
-
Nijnik A, Madera L, Ma S, Waldbrook M, Elliott MR, et al. (2010) Synthetic cationic peptide IDR-1002 provides protection against bacterial infections through chemokine induction and enhanced leukocyte recruitment. J Immunol 184: 2539-2550.
-
(2010)
J Immunol
, vol.184
, pp. 2539-2550
-
-
Nijnik, A.1
Madera, L.2
Ma, S.3
Waldbrook, M.4
Elliott, M.R.5
-
24
-
-
84871268218
-
Host defense peptides of thrombin modulate inflammation and coagulation in endotoxin-mediated shock and Pseudomonas aeruginosa sepsis
-
Kalle M, Papareddy P, Kasetty G, Morgelin M, van der Plas MJ, et al. (2012) Host defense peptides of thrombin modulate inflammation and coagulation in endotoxin-mediated shock and Pseudomonas aeruginosa sepsis. PLoS One 7: e51313.
-
(2012)
PLoS One
, vol.7
-
-
Kalle, M.1
Papareddy, P.2
Kasetty, G.3
Morgelin, M.4
Van Der Plas, M.J.5
-
25
-
-
84894536600
-
An antimicrobial helix A-derived peptide of heparin cofactor II blocks endotoxin responses in vivo
-
Papareddy P, Kalle M, Singh S, Morgelin M, Schmidtchen A, et al. (2014) An antimicrobial helix A-derived peptide of heparin cofactor II blocks endotoxin responses in vivo. Biochim Biophys Acta 1838: 1225-1234.
-
(2014)
Biochim Biophys Acta
, vol.1838
, pp. 1225-1234
-
-
Papareddy, P.1
Kalle, M.2
Singh, S.3
Morgelin, M.4
Schmidtchen, A.5
-
26
-
-
84881512401
-
Importance of lipopolysaccharide aggregate disruption for the anti-endotoxic effects of heparin cofactor II peptides
-
Singh S, Papareddy P, Kalle M, Schmidtchen A, Malmsten M (2013) Importance of lipopolysaccharide aggregate disruption for the anti-endotoxic effects of heparin cofactor II peptides. Biochim Biophys Acta 1828: 2709-2719.
-
(2013)
Biochim Biophys Acta
, vol.1828
, pp. 2709-2719
-
-
Singh, S.1
Papareddy, P.2
Kalle, M.3
Schmidtchen, A.4
Malmsten, M.5
-
27
-
-
84871027267
-
A comprehensive summary of LL-37, the factotum human cathelicidin peptide
-
Vandamme D, Landuyt B, Luyten W, Schoofs L (2012) A comprehensive summary of LL-37, the factotum human cathelicidin peptide. Cell Immunol 280: 22-35.
-
(2012)
Cell Immunol
, vol.280
, pp. 22-35
-
-
Vandamme, D.1
Landuyt, B.2
Luyten, W.3
Schoofs, L.4
-
28
-
-
77954060987
-
Proteolysis of human thrombin generates novel host defense peptides
-
Papareddy P, Rydengard V, Pasupuleti M, Walse B, Morgelin M, et al. (2010) Proteolysis of human thrombin generates novel host defense peptides. PLoS Pathog 6: e1000857.
-
(2010)
PLoS Pathog
, vol.6
-
-
Papareddy, P.1
Rydengard, V.2
Pasupuleti, M.3
Walse, B.4
Morgelin, M.5
-
29
-
-
30044433704
-
Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37
-
Mookherjee N, Brown KL, Bowdish DM, Doria S, Falsafi R, et al. (2006) Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37. J Immunol 176: 2455-2464. (Pubitemid 43201696)
-
(2006)
Journal of Immunology
, vol.176
, Issue.4
, pp. 2455-2464
-
-
Mookherjee, N.1
Brown, K.L.2
Bowdish, D.M.E.3
Doria, S.4
Falsafi, R.5
Hokamp, K.6
Roche, F.M.7
Mu, R.8
Doho, G.H.9
Pistolic, J.10
Powers, J.-P.11
Bryan, J.12
Brinkman, F.S.L.13
Hancock, R.E.W.14
-
30
-
-
0025774414
-
Ultrasensitive assays for endogenous antimicrobial polypeptides
-
Lehrer RI, Rosenman M, Harwig SS, Jackson R, Eisenhauer P (1991) Ultrasensitive assays for endogenous antimicrobial polypeptides. J Immunol Methods 137: 167-173.
-
(1991)
J Immunol Methods
, vol.137
, pp. 167-173
-
-
Lehrer, R.I.1
Rosenman, M.2
Harwig, S.S.3
Jackson, R.4
Eisenhauer, P.5
-
31
-
-
77956233304
-
C-terminal peptides of tissue factor pathway inhibitor are novel host defense molecules
-
Papareddy P, Kalle M, Kasetty G, Morgelin M, Rydengard V, et al. (2010) C-terminal peptides of tissue factor pathway inhibitor are novel host defense molecules. J Biol Chem 285: 28387-28398.
-
(2010)
J Biol Chem
, vol.285
, pp. 28387-28398
-
-
Papareddy, P.1
Kalle, M.2
Kasetty, G.3
Morgelin, M.4
Rydengard, V.5
-
32
-
-
39449086721
-
Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances
-
DOI 10.1038/nprot.2007.521, PII NPROT.2007.521
-
Wiegand I, Hilpert K, Hancock RE (2008) Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances. Nat Protoc 3: 163-175. (Pubitemid 351266501)
-
(2008)
Nature Protocols
, vol.3
, Issue.2
, pp. 163-175
-
-
Wiegand, I.1
Hilpert, K.2
Hancock, R.E.W.3
-
33
-
-
81455139902
-
Thymic stromal lymphopoietin exerts antimicrobial activities
-
Sonesson A, Kasetty G, Olin AI, Malmsten M, Morgelin M, et al. (2011) Thymic stromal lymphopoietin exerts antimicrobial activities. Exp Dermatol 20: 1004-1010.
-
(2011)
Exp Dermatol
, vol.20
, pp. 1004-1010
-
-
Sonesson, A.1
Kasetty, G.2
Olin, A.I.3
Malmsten, M.4
Morgelin, M.5
-
34
-
-
80052048215
-
The C-terminal sequence of several human serine proteases encodes host defense functions
-
Kasetty G, Papareddy P, Kalle M, Rydengard V, Walse B, et al. (2011) The C-terminal sequence of several human serine proteases encodes host defense functions. J Innate Immun 3: 471-482.
-
(2011)
J Innate Immun
, vol.3
, pp. 471-482
-
-
Kasetty, G.1
Papareddy, P.2
Kalle, M.3
Rydengard, V.4
Walse, B.5
-
35
-
-
50849129565
-
Rational design of antimicrobial C3a analogues with enhanced effects against Staphylococci using an integrated structure and function-based approach
-
Pasupuleti M, Walse B, Svensson B, Malmsten M, Schmidtchen A (2008) Rational design of antimicrobial C3a analogues with enhanced effects against Staphylococci using an integrated structure and function-based approach. Biochemistry 47: 9057-9070.
-
(2008)
Biochemistry
, vol.47
, pp. 9057-9070
-
-
Pasupuleti, M.1
Walse, B.2
Svensson, B.3
Malmsten, M.4
Schmidtchen, A.5
-
36
-
-
42149194280
-
Antimicrobial activity of omiganan pentahydrochloride tested against contemporary bacterial pathogens commonly responsible for catheter-associated infections
-
DOI 10.1093/jac/dkn074
-
Fritsche TR, Rhomberg PR, Sader HS, Jones RN (2008) Antimicrobial activity of omiganan pentahydrochloride tested against contemporary bacterial pathogens commonly responsible for catheter-associated infections. J Antimicrob Chemother 61: 1092-1098. (Pubitemid 351524455)
-
(2008)
Journal of Antimicrobial Chemotherapy
, vol.61
, Issue.5
, pp. 1092-1098
-
-
Fritsche, T.R.1
Rhomberg, P.R.2
Sader, H.S.3
Jones, R.N.4
-
37
-
-
0742324860
-
TLR signaling pathways
-
DOI 10.1016/j.smim.2003.10.003
-
Takeda K, Akira S (2004) TLR signaling pathways. Semin Immunol 16: 3-9. (Pubitemid 38147427)
-
(2004)
Seminars in Immunology
, vol.16
, Issue.1
, pp. 3-9
-
-
Takeda, K.1
Akira, S.2
-
38
-
-
34547510802
-
Structural biology of the LPS recognition
-
Jerala R (2007) Structural biology of the LPS recognition. Int J Med Microbiol 297: 353-363.
-
(2007)
Int J Med Microbiol
, vol.297
, pp. 353-363
-
-
Jerala, R.1
-
39
-
-
79956330145
-
Structure-activity studies and therapeutic potential of host defense peptides of human thrombin
-
Kasetty G, Papareddy P, Kalle M, Rydengard V, Morgelin M, et al. (2011) Structure-activity studies and therapeutic potential of host defense peptides of human thrombin. Antimicrob Agents Chemother 55: 2880-2890.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 2880-2890
-
-
Kasetty, G.1
Papareddy, P.2
Kalle, M.3
Rydengard, V.4
Morgelin, M.5
-
40
-
-
0027474382
-
Defensins: Antimicrobial and cytotoxic peptides of mammalian cells
-
Lehrer RI, Lichtenstein AK, Ganz T (1993) Defensins: antimicrobial and cytotoxic peptides of mammalian cells. Annu Rev Immunol 11: 105-128. (Pubitemid 23115003)
-
(1993)
Annual Review of Immunology
, vol.11
, pp. 105-128
-
-
Lehrer, R.I.1
Lichtenstein, A.K.2
Ganz, T.3
-
41
-
-
84873714375
-
Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock, 2012
-
Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, et al. (2013) Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med 39: 165-228.
-
(2013)
Intensive Care Med
, vol.39
, pp. 165-228
-
-
Dellinger, R.P.1
Levy, M.M.2
Rhodes, A.3
Annane, D.4
Gerlach, H.5
-
42
-
-
0033576811
-
Disseminated intravascular coagulation
-
DOI 10.1056/NEJM199908193410807
-
Levi M, Ten CateH(1999) Disseminated intravascular coagulation. N Engl J Med 341: 586-592. (Pubitemid 29384168)
-
(1999)
New England Journal of Medicine
, vol.341
, Issue.8
, pp. 586-592
-
-
Levi, M.1
Ten, C.H.2
-
44
-
-
84858753893
-
Antimicrobial peptides and their potential application in inflammation and sepsis
-
Schuerholz T, Brandenburg K, Marx G (2012) Antimicrobial peptides and their potential application in inflammation and sepsis. Crit Care 16: 207.
-
(2012)
Crit Care
, vol.16
, pp. 207
-
-
Schuerholz, T.1
Brandenburg, K.2
Marx, G.3
-
45
-
-
16844381376
-
Impact of LL-37 on anti-infective immunity
-
DOI 10.1189/jlb.0704380
-
Bowdish DM, Davidson DJ, Lau YE, Lee K, Scott MG, et al. (2005) Impact of LL-37 on anti-infective immunity. J Leukoc Biol 77: 451-459. (Pubitemid 40489520)
-
(2005)
Journal of Leukocyte Biology
, vol.77
, Issue.4
, pp. 451-459
-
-
Bowdish, D.M.E.1
Davidson, D.J.2
Lau, Y.E.3
Lee, K.4
Scott, M.G.5
Hancock, R.E.W.6
-
46
-
-
2642635843
-
Activation of the contact-phase system on bacterial surfaces - A clue to serious comlications in infections deseases
-
DOI 10.1038/nm0398-298
-
Herwald H, Morgelin M, Olsen A, Rhen M, Dahlback B, et al. (1998) Activation of the contact-phase system on bacterial surfaces - a clue to serious complications in infectious diseases. Nat Med 4: 298-302. (Pubitemid 28144087)
-
(1998)
Nature Medicine
, vol.4
, Issue.3
, pp. 298-302
-
-
Herwald, H.1
Morgelin, M.2
Olsen, A.3
Rhen, M.4
Dahlback, B.5
Muller-Esterl, W.6
Bjorck, L.7
-
47
-
-
77951205291
-
Contact system activation in severe infectious diseases
-
Oehmcke S, Herwald H (2010) Contact system activation in severe infectious diseases. J Mol Med (Berl) 88: 121-126.
-
(2010)
J Mol Med (Berl)
, vol.88
, pp. 121-126
-
-
Oehmcke, S.1
Herwald, H.2
-
48
-
-
13444283302
-
Dynamic evolution of coagulopathy in the first day of severe sepsis: Relationship with mortality and organ failure
-
DOI 10.1097/01.CCM.0000153520.31562.48
-
Dhainaut JF, Shorr AF, Macias WL, Kollef MJ, Levi M, et al. (2005) Dynamic evolution of coagulopathy in the first day of severe sepsis: relationship with mortality and organ failure. Crit Care Med 33: 341-348. (Pubitemid 40216547)
-
(2005)
Critical Care Medicine
, vol.33
, Issue.2
, pp. 341-348
-
-
Dhainaut, J.-F.1
Shorr, A.F.2
Macias, W.L.3
Kollef, M.J.4
Levi, M.5
Reinhart, K.6
Nelson, D.R.7
-
49
-
-
34548496023
-
Therapeutic effects of TAK-242, a novel selective Toll-like receptor 4 signal transduction inhibitor, in mouse endotoxin shock model
-
DOI 10.1016/j.ejphar.2007.06.027, PII S0014299907007340
-
Sha T, Sunamoto M, Kitazaki T, Sato J, Ii M, et al. (2007) Therapeutic effects of TAK-242, a novel selective Toll-like receptor 4 signal transduction inhibitor, in mouse endotoxin shock model. Eur J Pharmacol 571: 231-239. (Pubitemid 47379694)
-
(2007)
European Journal of Pharmacology
, vol.571
, Issue.2-3
, pp. 231-239
-
-
Sha, T.1
Sunamoto, M.2
Kitazaki, T.3
Sato, J.4
Ii, M.5
Iizawa, Y.6
-
50
-
-
34249318067
-
Cytokine profiles as markers of disease severity in sepsis: A multiplex analysis
-
Bozza FA, Salluh JI, Japiassu AM, Soares M, Assis EF, et al. (2007) Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis. Crit Care 11: R49.
-
(2007)
Crit Care
, vol.11
-
-
Bozza, F.A.1
Salluh, J.I.2
Japiassu, A.M.3
Soares, M.4
Assis, E.F.5
-
52
-
-
84875049604
-
Biomarkers of sepsis
-
Faix JD (2013) Biomarkers of sepsis. Crit Rev Clin Lab Sci 50: 23-36.
-
(2013)
Crit Rev Clin Lab Sci
, vol.50
, pp. 23-36
-
-
Faix, J.D.1
-
53
-
-
0028129179
-
Interleukin 6 is a prognostic indicator of outcome in severe intra-abdominal sepsis
-
Patel RT, Deen KI, Youngs D, Warwick J, Keighley MR (1994) Interleukin 6 is a prognostic indicator of outcome in severe intra-abdominal sepsis. Br J Surg 81: 1306-1308. (Pubitemid 24275149)
-
(1994)
British Journal of Surgery
, vol.81
, Issue.9
, pp. 1306-1308
-
-
Patel, R.T.1
Deen, K.I.2
Youngs, D.3
Warwick, J.4
Keighley, M.R.B.5
-
54
-
-
34249732658
-
Role of the innate immune system in host defence against bacterial infections: Focus on the Toll-like receptors
-
DOI 10.1111/j.1365-2796.2007.01821.x
-
Albiger B, Dahlberg S, Henriques-Normark B, Normark S (2007) Role of the innate immune system in host defence against bacterial infections: focus on the Toll-like receptors. J Intern Med 261: 511-528. (Pubitemid 46835986)
-
(2007)
Journal of Internal Medicine
, vol.261
, Issue.6
, pp. 511-528
-
-
Albiger, B.1
Dahlberg, S.2
Henriques-Normark, B.3
Normark, S.4
|