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Volumn 7, Issue JULY, 2014, Pages

MicroRNAs targeting Nicastrin regulate Aβ production and are affected by target site polymorphisms

Author keywords

Alzheimer's disease; MicroRNA; MiR 186; MiR 455; Nicastrin; Single nucleotide polymorphism

Indexed keywords

AMYLOID BETA PROTEIN; MICRORNA; MICRORNA 186; MICRORNA 24; MICRORNA 455; NICASTRIN; UNCLASSIFIED DRUG;

EID: 84904473741     PISSN: 16625099     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnmol.2014.00067     Document Type: Article
Times cited : (23)

References (25)
  • 1
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • doi: 10.1038/nature02871
    • Ambros, V. (2004). The functions of animal microRNAs. Nature 431, 350-355. doi: 10.1038/nature02871
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 2
    • 0028296884 scopus 로고
    • Canadian study of health and aging: Study methods and prevalence of dementia
    • Anonymous
    • Anonymous. (1994). Canadian study of health and aging: study methods and prevalence of dementia. CMAJ 150, 899-913.
    • (1994) CMAJ , vol.150 , pp. 899-913
  • 3
    • 38549124383 scopus 로고    scopus 로고
    • The microRNA. org resource: Targets and expression
    • doi: 10.1093/nar/gkm995
    • Betel, D., Wilson, M., Gabow, A., Marks, D. S., and Sander, C. (2008). The microRNA. org resource: targets and expression. Nucleic Acids Res. 36, D149-D153. doi: 10.1093/nar/gkm995
    • (2008) Nucleic Acids Res. , vol.36
    • Betel, D.1    Wilson, M.2    Gabow, A.3    Marks, D.S.4    Sander, C.5
  • 4
    • 33751520430 scopus 로고    scopus 로고
    • Natural selection on human microRNA binding sites inferred from SNP data
    • doi: 10.1038/ng1910
    • Chen, K., and Rajewsky, N. (2006). Natural selection on human microRNA binding sites inferred from SNP data. Nat. Genet. 38, 1452-1456. doi: 10.1038/ng1910
    • (2006) Nat. Genet. , vol.38 , pp. 1452-1456
    • Chen, K.1    Rajewsky, N.2
  • 5
    • 80053477918 scopus 로고    scopus 로고
    • Alzheimer-specific variants in the 3′UTR of Amyloid precursor protein affect microRNA function
    • doi: 10.1186/1750-1326-6-70
    • Delay, C., Calon, F., Mathews, P., and Hébert, S. S. (2011). Alzheimer-specific variants in the 3′UTR of Amyloid precursor protein affect microRNA function. Mol. Neurodegener. 6, 70. doi: 10.1186/1750-1326-6-70
    • (2011) Mol. Neurodegener. , vol.6 , pp. 70
    • Delay, C.1    Calon, F.2    Mathews, P.3    Hébert, S.S.4
  • 6
    • 84859503786 scopus 로고    scopus 로고
    • MicroRNAs in Alzheimer's disease
    • doi: 10.1016/j.nbd.2012.01.003
    • Delay, C., Mandemakers, W., and Hébert, S. S. (2012). MicroRNAs in Alzheimer's disease. Neurobiol. Dis. 46, 285-290. doi: 10.1016/j.nbd.2012.01.003
    • (2012) Neurobiol. Dis. , vol.46 , pp. 285-290
    • Delay, C.1    Mandemakers, W.2    Hébert, S.S.3
  • 7
    • 0037431082 scopus 로고    scopus 로고
    • Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex
    • doi: 10.1016/S0896-6273(03)00205-8
    • De Strooper, B. (2003). Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex. Neuron 38, 9-12. doi: 10.1016/S0896-6273(03)00205-8
    • (2003) Neuron , vol.38 , pp. 9-12
    • De Strooper, B.1
  • 8
    • 0037173115 scopus 로고    scopus 로고
    • Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formation
    • doi: 10.1073/pnas.132277899
    • Edbauer, D., Winkler, E., Haass, C., and Steiner, H. (2002). Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formation. Proc. Natl. Acad. Sci. U.S.A. 99, 8666-8671. doi: 10.1073/pnas.132277899
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 8666-8671
    • Edbauer, D.1    Winkler, E.2    Haass, C.3    Steiner, H.4
  • 9
    • 0043163673 scopus 로고    scopus 로고
    • A Canadian cohort study of cognitive impairment and related dementias (ACCORD): Study methods and baseline results
    • doi: 10.1159/000071189
    • Feldman, H., Levy, A. R., Hsiung, G.-Y., Peters, K. R., Donald, A., Black, S. E., et al. (2003). A Canadian cohort study of cognitive impairment and related dementias (ACCORD): study methods and baseline results. Neuroepidemiology22, 265-274. doi: 10.1159/000071189
    • (2003) Neuroepidemiology , vol.22 , pp. 265-274
    • Feldman, H.1    Levy, A.R.2    Hsiung, G.-Y.3    Peters, K.R.4    Donald, A.5    Black, S.E.6
  • 10
    • 84862114807 scopus 로고    scopus 로고
    • Genetic architecture of microRNA expression: Implications for the transcriptome and complex traits
    • doi: 10.1016/j.ajhg.2012.04.023
    • Gamazon, E. R., Ziliak, D., Im, H. K., LaCroix, B., Park, D. S., Cox, N. J., et al. (2012). Genetic architecture of microRNA expression: implications for the transcriptome and complex traits. Am. J. Hum. Genet. 90, 1046-1063. doi: 10.1016/j.ajhg.2012.04.023
    • (2012) Am. J. Hum. Genet. , vol.90 , pp. 1046-1063
    • Gamazon, E.R.1    Ziliak, D.2    Im, H.K.3    LaCroix, B.4    Park, D.S.5    Cox, N.J.6
  • 11
    • 80455154984 scopus 로고    scopus 로고
    • Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs
    • doi: 10.1038/nsmb.2115
    • Garcia, D. M., Baek, D., Shin, C., Bell, G. W., Grimson, A., and Bartel, D. P. (2011). Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs. Nat. Struct. Mol. Biol. 18, 1139-1146. doi: 10.1038/nsmb.2115
    • (2011) Nat. Struct. Mol. Biol. , vol.18 , pp. 1139-1146
    • Garcia, D.M.1    Baek, D.2    Shin, C.3    Bell, G.W.4    Grimson, A.5    Bartel, D.P.6
  • 12
    • 0021256895 scopus 로고
    • Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
    • doi: 10.1016/S0006-291X(84)80190-4
    • Glenner, G. G., and Wong, C. W. (1984). Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem. Biophys. Res. Commun. 120, 885-890. doi: 10.1016/S0006-291X(84)80190-4
    • (1984) Biochem. Biophys. Res. Commun. , vol.120 , pp. 885-890
    • Glenner, G.G.1    Wong, C.W.2
  • 13
    • 84880923071 scopus 로고    scopus 로고
    • Nicastrin overexpression in transgenic mice lnduces aberrant behavior and APP processing
    • doi: 10.1007/s12035-013-8453-3
    • Goo, J. S., Kim, Y. B., Shim, S. B., Jee, S. W., Lee, S. H., Kim, J. E., et al. (2013). Nicastrin overexpression in transgenic mice lnduces aberrant behavior and APP processing. Mol. Neurobiol. 48, 232-243. doi: 10.1007/s12035-013-8453-3
    • (2013) Mol. Neurobiol. , vol.48 , pp. 232-243
    • Goo, J.S.1    Kim, Y.B.2    Shim, S.B.3    Jee, S.W.4    Lee, S.H.5    Kim, J.E.6
  • 14
    • 84877117884 scopus 로고    scopus 로고
    • A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer's disease, dementia with lewy bodies, hippocampal sclerosis, frontotemporal lobar dementia, and non-demented human controls
    • doi: 10.3233/JAD-122350
    • Hébert, S. S., Wang, W.-X., Zhu, Q., and Nelson, P. T. (2013). A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer's disease, dementia with lewy bodies, hippocampal sclerosis, frontotemporal lobar dementia, and non-demented human controls. J. Alzheimers Dis. 35, 335-348. doi: 10.3233/JAD-122350
    • (2013) J. Alzheimers Dis. , vol.35 , pp. 335-348
    • Hébert, S.S.1    Wang, W.-X.2    Zhu, Q.3    Nelson, P.T.4
  • 15
    • 5644241911 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon4 genotype as a risk factor for cognitive decline and dementia: Data from the Canadian Study of Health and Aging
    • doi: 10.1503/cmaj.1031789
    • Hsiung, G.-Y., Sadovnick, A. D., and Feldman, H. (2004). Apolipoprotein E epsilon4 genotype as a risk factor for cognitive decline and dementia: data from the Canadian Study of Health and Aging. CMAJ 171, 863-867. doi: 10.1503/cmaj.1031789
    • (2004) CMAJ , vol.171 , pp. 863-867
    • Hsiung, G.-Y.1    Sadovnick, A.D.2    Feldman, H.3
  • 16
    • 79952141389 scopus 로고    scopus 로고
    • Deep sequencing of the Nicastrin gene in pooled DNA, the identification of genetic variants that affect risk of Alzheimer's disease
    • doi: 10.1371/journal.pone.0017298
    • Lupton, M. K., Proitsi, P., Danillidou, M., Tsolaki, M., Hamilton, G., Wroe, R., et al. (2011). Deep sequencing of the Nicastrin gene in pooled DNA, the identification of genetic variants that affect risk of Alzheimer's disease. PLoS ONE6:e17298. doi: 10.1371/journal.pone.0017298
    • (2011) PLoS ONE , vol.6
    • Lupton, M.K.1    Proitsi, P.2    Danillidou, M.3    Tsolaki, M.4    Hamilton, G.5    Wroe, R.6
  • 17
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • doi: 10.1212/WNL.34.7.939
    • McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., and Stadlan, E. M. (1984). Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939-944. doi: 10.1212/WNL.34.7.939
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 18
    • 0242321947 scopus 로고    scopus 로고
    • Presenilins mutated at Asp-257 or Asp-385 restore Pen-2 expression and Nicastrin glycosylation but remain catalytically inactive in the absence of wild type Presenilin
    • doi: 10.1074/jbc.M306957200
    • Nyabi, O., Bentahir, M., Horré, K., Herreman, A., Gottardi-Littell, N., Van Broeckhoven, C., et al. (2003). Presenilins mutated at Asp-257 or Asp-385 restore Pen-2 expression and Nicastrin glycosylation but remain catalytically inactive in the absence of wild type Presenilin. J. Biol. Chem. 278, 43430-43436. doi: 10.1074/jbc.M306957200
    • (2003) J. Biol. Chem. , vol.278 , pp. 43430-43436
    • Nyabi, O.1    Bentahir, M.2    Horré, K.3    Herreman, A.4    Gottardi-Littell, N.5    Van Broeckhoven, C.6
  • 19
    • 28344440823 scopus 로고    scopus 로고
    • MicroRNA function: Multiple mechanisms for a tiny RNA?
    • doi: 10.1261/rna.2248605
    • Pillai, R. S. (2005). MicroRNA function: multiple mechanisms for a tiny RNA? RNA 11, 1753-1761. doi: 10.1261/rna.2248605
    • (2005) RNA , vol.11 , pp. 1753-1761
    • Pillai, R.S.1
  • 20
    • 56049083010 scopus 로고    scopus 로고
    • Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia
    • doi: 10.1093/hmg/ddn257
    • Rademakers, R., Eriksen, J. L., Baker, M., Robinson, T., Ahmed, Z., Lincoln, S. J., et al. (2008). Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia. Hum. Mol. Genet. 17, 3631-3642. doi: 10.1093/hmg/ddn257
    • (2008) Hum. Mol. Genet. , vol.17 , pp. 3631-3642
    • Rademakers, R.1    Eriksen, J.L.2    Baker, M.3    Robinson, T.4    Ahmed, Z.5    Lincoln, S.J.6
  • 21
    • 80053901650 scopus 로고    scopus 로고
    • A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS
    • doi: 10.1186/1471-2164-12-504
    • Richardson, K., Lai, C.-Q., Parnell, L. D., Lee, Y.-C., and Ordovas, J. M. (2011). A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS. BMC Genomics 12:504. doi: 10.1186/1471-2164-12-504
    • (2011) BMC Genomics , vol.12 , pp. 504
    • Richardson, K.1    Lai, C.-Q.2    Parnell, L.D.3    Lee, Y.-C.4    Ordovas, J.M.5
  • 22
    • 33847665108 scopus 로고    scopus 로고
    • Human polymorphism at microRNAs and microRNA target sites
    • doi: 10.1073/pnas.0611347104
    • Saunders, M. A., Liang, H., and Li, W.-H. (2007). Human polymorphism at microRNAs and microRNA target sites. Proc. Natl. Acad. Sci. U.S.A. 104, 3300-3305. doi: 10.1073/pnas.0611347104
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 3300-3305
    • Saunders, M.A.1    Liang, H.2    Li, W.-H.3
  • 23
    • 80052476453 scopus 로고    scopus 로고
    • Inferring causative variants in microRNA target sites
    • doi: 10.1093/nar/gkr414
    • Thomas, L. F., Saito, T., and Sætrom, P. (2011). Inferring causative variants in microRNA target sites. Nucleic Acids Res. 39:e109. doi: 10.1093/nar/gkr414
    • (2011) Nucleic Acids Res. , vol.39
    • Thomas, L.F.1    Saito, T.2    Sætrom, P.3
  • 24
    • 40749145370 scopus 로고    scopus 로고
    • Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein
    • doi: 10.1016/j.ajhg.2007.09.021
    • Wang, G., van Der Walt, J. M., Mayhew, G., Li, Y.-J., Züchner, S., Scott, W. K., et al. (2008). Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. Am. J. Hum. Genet. 82, 283-289. doi: 10.1016/j.ajhg.2007.09.021
    • (2008) Am. J. Hum. Genet. , vol.82 , pp. 283-289
    • Wang, G.1    van Der Walt, J.M.2    Mayhew, G.3    Li, Y.-J.4    Züchner, S.5    Scott, W.K.6
  • 25
    • 34547843634 scopus 로고    scopus 로고
    • Aberrant allele frequencies of the SNPs located in microRNA target sites are potentially associated with human cancers
    • doi: 10.1093/nar/gkm480
    • Yu, Z., Li, Z., Jolicoeur, N., Zhang, L., Fortin, Y., Wang, E., et al. (2007). Aberrant allele frequencies of the SNPs located in microRNA target sites are potentially associated with human cancers. Nucleic Acids Res. 35, 4535-4541. doi: 10.1093/nar/gkm480
    • (2007) Nucleic Acids Res. , vol.35 , pp. 4535-4541
    • Yu, Z.1    Li, Z.2    Jolicoeur, N.3    Zhang, L.4    Fortin, Y.5    Wang, E.6


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