Heritability analysis of IgG4 antibodies in autoimmune thyroid disease

Autoimmunity

Volumn 47, Issue 5, 2014, Pages 320-326

  Outschoorn, I M ^a   Talor, M V ^b   Burek, C L ^b   Hoffman, W H ^c   Rose, N R ^b,d  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

^d JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Autoimmune thyroid disease; Autoimmunity genetics; Heritability; IgG4 related thyroid disease; ROMP plots

Indexed keywords

IMMUNOGLOBULIN ANTIBODY; IMMUNOGLOBULIN G4 ANTIBODY; THYROGLOBULIN ANTIBODY; THYROID PEROXIDASE ANTIBODY; UNCLASSIFIED DRUG; AUTOANTIBODY; IMMUNOGLOBULIN G; IODIDE PEROXIDASE; THYROGLOBULIN;

ADOLESCENT; ADULT; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; ASYMPTOMATIC DISEASE; AUTOIMMUNE DISEASE; CHILD; CLINICAL ARTICLE; FAMILY; FEMALE; GENETIC ANALYSIS; GENETIC SCREENING; GRAVES DISEASE; HASHIMOTO DISEASE; HERITABILITY; HUMAN; IMMUNOGLOBULIN G4 RELATED DISEASE; MALE; PARENT; SCHOOL CHILD; THYROID DISEASE; THYROIDITIS; THYROTOXICOSIS; AUTOIMMUNE THYROIDITIS; GENETICS; IMMUNOLOGY; PREDICTIVE VALUE; RETROSPECTIVE STUDY;

ADOLESCENT; ADULT; AUTOANTIBODIES; FEMALE; HUMANS; IMMUNOGLOBULIN G; IODIDE PEROXIDASE; MALE; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; THYROGLOBULIN; THYROIDITIS, AUTOIMMUNE;

EID: 84904439661     PISSN: 08916934     EISSN: 1607842X     Source Type: Journal    
DOI: 10.3109/08916934.2014.897331     Document Type: Article

References (55)

1. Masaki, Y., N. Kurose, and H. Umehara. 2011. IgG4-related disease: a novel lymphoproliferative disorder discovered and established in Japan in the 21st century. J. Clin. Exp. Hematop.51: 13-20.
2. Ebbo, M., A. Grados, E. Bernit, et al. 2012. Pathologies associated with serum IgG4 elevation. Int. J. Rheumatol. 2012: 602809.
3. Mahajan, V. S., H. Mattoo, V. Deshpande, et al. 2014. IgG4-Related Disease. Annu. Rev. Pathol. Mech. Dis. 9: 315-347.
4. Li, Y., Y. Bai, and Z. Liu, et al. 2009. Immunohistochemistry of IgG4 can help subclassify Hashimotos autoimmune thyroiditis. Pathol. Int. 59: 636-641.
5. Zhang, J., L. Zhao, Y. Gao, et al. 2013. A classification of Hashimotos thyroiditis based on immunohistochemistry for IgG4 and IgG. Thyroid. 24: 364-370.
6. Deshpande, V., A. Huck, E. Ooi, et al. 2012. Fibrosing variant of Hashimoto thyroiditis is an IgG4 related disease. J. Clin. Pathol. 65: 725-728.
7. Shimizu, Y., M. Yamamoto, Y. Naishiro, et al. 2013. Necessity of early intervention for IgG4-related disease-delayed treatment induces fibrosis progression. Rheumatology (Oxford). 52: 679-683.
8. Guma, M., and G. S. Firestein. 2012. IgG4-related diseases. Best. Pract. Res. Clin. Rheumatol. 26: 425-438.
9. Palazzo, E., C. Palazzo, and M. Palazzo. 2013. IgG4-related disease. Joint Bone Spine. 81: 27-31.
10. Kamisawa, T., S. T. Chari, M. M. Lerch, et al. 2014. Recent advances in autoimmune pancreatitis: type 1 and type 2. Postgrad. Med. J. 90: 18-25.
11. Koike, T. 2013. IgG4-related disease: why high IgG4 and fibrosis? Arthritis Res. Ther. 15: 103.
12. Lee, L. H., E. A. Shaffer, V. Falck, and M. M. Kelly. 2013. Solitary lesions with fibrosis and increased IgG4+ plasma cells: Part of the expanding spectrum of IgG4-related disease or a nonspecific inflammatory response? Int. J. Surg. Pathol. [Epub ahead of print]. doi: 10.1177/1066896913513832.
13. Moroni, L., I. Bianchi, and A. Lleo. 2012. Geoepidemiology, gender and autoimmune disease. Autoimmun. Rev. 11: A386-92.
14. Burek, C. L., W. H. Hoffman, and N. R. Rose. 1982. The presence of thyroid autoantibodies in children and adolescents with autoimmune thyroid disease and in their siblings and parents. Clin. Immunol. Immunopathol. 25: 395-404. (Pubitemid 13167799)
15. Burek, C.L., N. R. Rose, G. M. Najar, et al. 1984. Autoimmune Thyroid Disease. In Clinical Immunology, Vol. 1 - Immunogenetics. C. S. David, and G. S. Panayi, eds. Butterworths, London. p. 207-233.
16. Li, Y., E. Nishihara, and K. Kakudo. 2011. Hashimotos thyroiditis: old concepts and new insights. Curr. Opin. Rheumatol. 23: 102-107.
17. Jabrocka-Hybel, A., A. Skalniak, J. Pia̧tkowski, et al. 2013. How far are we from understanding the genetic basis of Hashimotos thyroiditis? Int. Rev. Immunol. 32: 337-354.
18. Manolio, T. A., K. C. Barnes, T. H. Beaty, et al. 2003. Sex differences in heritability of sensitization to Blomia tropicalis in asthma using regression of offspring on midparent (ROMP) methods. Hum. Genet. 113: 437-446. (Pubitemid 37254248)
19. Outschoorn, I. M., M. V. Talor, W. H. Hoffman, et al. 2011. Autoantibody heritability in thyroiditis: IgG subclass contributions. Autoimmunity. 44: 195-200.
20. Kuppers, R. C., I. M. Outschoorn, R. G. Hamilton, et al. 1993. Quantitative measurement of human thyroglobulin-specific antibodies by use of a sensitive enzyme-linked immunoassay. Clin. Immunol. Immunopathol. 67: 68-77. (Pubitemid 23100066)
21. Beastall, G. H. 2014. What is the significance of antithyroid antibodies in children and adolescents? Clin. Biochem. 47: 1-2.
22. Taubner, K., G. Schubert, F. Pulzer, et al. 2014. Serum concentrations of anti-thyroid peroxidase and anti-thyroglobulin antibodies in children and adolescents without apparent thyroid disorders. Clin. Biochem. 47: 3-7.
23. Hart, P. A., T. Kamisawa, W. R. Brugge, et al. 2013. Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis. Gut. 62: 1771-1776.
24. Yamamoto, M., T. Tabeya, Y. Naishiro, et al. 2012. Value of serum IgG4 in the diagnosis of IgG4-related disease and in differentiation from rheumatic diseases and other diseases. Mod. Rheumatol. 22: 419-425.
25. Tsuboi, H., H. Asashima, C. Takai, et al. 2013. Primary and secondary surveys on epidemiology of Sjögrens syndrome in Japan. Mod. Rheumatol. [Epub ahead of print]. doi: 10.3109/14397595.2013.843765.
26. Yang, Y., X. Su, K. Zhang, and R. Zhou. 2013. The Fc receptor-like 3 gene polymorphisms and susceptibility to autoimmune diseases: an updated meta-analysis. Autoimmunity. 46: 547-558.
27. Yang, Y., K. Zhang, and R. Zhou. 2014. Meta-analysis of premiRNA polymorphisms association with susceptibility to autoimmune diseases. Immunol. Invest. 43: 13-27.
28. Duntas, L. H. 2011. Environmental factors and thyroid autoimmunity. Ann. Endocrinol. (Paris). 72: 108-113.
29. McLeod, D. S., and D. S. Cooper. 2012. The incidence and prevalence of thyroid autoimmunity. Endocrine. 42: 252-265.
30. Temajo, N. O., and N. Howard. 2014. The mosaic of environment involvement in autoimmunity: the abrogation of viral latency by stress, a non-infectious environmental agent, is an intrinsic prerequisite prelude before viruses can rank as infectious environmental agents that trigger autoimmune diseases. Autoimmun. Rev. [Epub ahead of print]. doi: 10.1016/j.autrev.2013.12.003.
31. de Buy Wenniger, L. J., E. L. Culver, and U. Beuers. 2014. Exposure to occupational antigens might predispose to IgG4- related disease. Hepatology. [Epub ahead of print]. doi: 10.1002/hep.26999.
32. Yamamoto, M., H. Takahashi, and K. Ishigami, et al. 2012. Relapse patterns in IgG4-related disease. Ann. Rheum. Dis. 71: 1755.
33. Murakami J., Matsui S., Ishizawa S., et al. 2013. Recurrence of IgG4-related disease following treatment with rituximab. Mod. Rheumatol. 23: 1226-1230.
34. Arlt, M. F., T. E. Wilson, and T. W. Glover. 2012. Replication stress and mechanisms of CNV formation. Curr. Opin. Genet. Dev. 22: 204-210.
35. Inoue, N., M. Watanabe, H. Yamada, et al. 2012. Associations between autoimmune thyroid disease prognosis and functional polymorphisms of susceptibility genes, CTLA4, PTPN22, CD40, FCRL3, and ZFAT, previously revealed in genome-wide association studies. J. Clin. Immunol. 32: 1243-1252.
36. Brix, T. H., and L. Hegedüs. 2012. Twin studies as a model for exploring the aetiology of autoimmune thyroid disease. Clin. Endocrinol (Oxf). 76: 457-464.
37. Parkes, A. B., S. M. McLachlan, P. Bird, and B. Rees Smith. 1984. The distribution of microsomal and thyroglobulin antibody activity among the IgG subclasses. Clin. Exp. Immunol. 57: 239-243. (Pubitemid 14083851)
38. McLachlan, S. M., and B. Rapoport. 2008. Thyroid peroxidase autoantibody epitopes revisited. Clin. Endocrinol (Oxf). 69: 526-527.
39. Yamamoto, M., H. Takahashi, K. Ishigami, et al. 2012. Evaluation and clinical validity of a new questionnaire for Mikuliczs disease. Int. J. Rheumatol. 2012: 283459.
40. Watanabe, T., M. Maruyama, T. Ito, et al. 2013. Two siblings with type 1 autoimmune pancreatitis. Intern. Med. 52: 895-899.
41. Okazaki, K., and H. Umehara. 2012. Are Classification Criteria for IgG4-RD Now Possible? The concept of IgG4-related disease and proposal of comprehensive diagnostic criteria in Japan. Int. J. Rheumatol. 2012: 357071.
42. Watanabe, T., M. Maruyama, T. Ito, et al. 2013. Clinical features of a new disease concept, IgG4-related thyroiditis. Scand. J. Rheumatol. 42: 325-330.
43. Kawashima, S. T., T. Tagami, K. Nakao, et al. 2013. Serum levels of IgG and IgG4 in Hashimoto thyroiditis. Endocrine. 45: 236-243.
44. Li, D., W. Cai, R. Gu, et al. 2013. Th17 cell plays a role in the pathogenesis of Hashimotos thyroiditis in patients. Clin. Immunol. 149: 411-420.
45. Ban, Y., T. Tozaki, M. Taniyama, et al. 2012. Multiple SNPs in intron 41 of thyroglobulin gene are associated with autoimmune thyroid disease in the Japanese population. PLoS One. 7: e37501.
46. Ban, Y., T. Tozaki, and M. Taniyama. 2013. The replication of the association of the rs9355610 within 6p27 with Graves disease. Autoimmunity. 46: 395-398.
47. Alkhateeb, A., N. A. Marzouka, and R. Tashtoush. 2013. Variants in PTPN22 and SMOC2 genes and the risk of thyroid disease in the Jordanian Arab population. Endocrine. 44: 702-709.
48. Alkhateeb, A., Y. Jarun, and R. Tashtoush. 2013. Polymorphisms in NLRP1 gene and susceptibility to autoimmune thyroid disease. Autoimmunity. 46: 215-221.
49. Zaaber, I., S. Mestiri, H. Marmouch, et al. 2013. Polymorphisms in TSHR and IL1RN genes and the risk and prognosis of Hashimotos thyroiditis. Autoimmunity. 47: 113-118.
50. Yan, N., Y. L. Yu, J. Yang, et al. 2012. Association of interleukin- 17A and -17F gene single-nucleotide polymorphisms with autoimmune thyroid diseases. Autoimmunity. 45: 533-539.
51. Weetman, A. 2013. A hundred years of Hashimotos thyroiditis. Thyroid. 23: 135-136.
52. Culver, E. L., and A. C. Bateman. 2013. General principles of IgG4-related disease. Mini-Symposium. Diagnostic Histopathology. 19:111-118.
53. Duntas, L.H., Y. Hiromatsu, and N. Amino. 2013. Centennial of the description of Hashimotos thyroiditis: two thought-provoking events. Thyroid. 23: 643-645.
54. Simmonds, M. J., F. K. Kavvoura, O. J. Brand, et al. 2014. Skewed x chromosome inactivation and female preponderance in autoimmune thyroid disease: an association study and meta-analysis. J. Clin. Endocrinol. Metab. 99: E127-E131.
55. Hunt, K. A., V. Mistry, N. A. Bockett, et al. 2013. Negligible impact of rare autoimmune-locus coding-region variants on missing heritability. Nature. 498: 232-235.