Small interfering RNAs targeted to interleukin-4 and respiratory syncytial virus reduce airway inflammation in a mouse model of virus-induced asthma exacerbation

Human Gene Therapy

Volumn 25, Issue 7, 2014, Pages 642-650

  Khaitov, Musa R ^a   Shilovskiy, Igor P ^a   Nikonova, Aleksandra A ^a,b   Shershakova, Nadezda N ^a   Kamyshnikov, Oleg Y ^a   Babakhin, Alexander A ^a   Zverev, Vitaly V ^b   Johnston, Sebastian L ^c   Khaitov, Rakhim M ^a  

^a INSTITUTE OF IMMUNOLOGY   (Russian Federation)

^b MECHNIKOV RESEARCH INSTITUTE FOR VACCINES AND SERA   (Russian Federation)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 4; OVALBUMIN; SMALL INTERFERING RNA; VIRUS RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; CELL COUNT; CONTROLLED STUDY; DISEASE EXACERBATION; DOWN REGULATION; EOSINOPHILIA; FEMALE; GENE SILENCING; HUMAN; LUNG LAVAGE; MOUSE MODEL; NONHUMAN; PLASMID; RAT; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY TRACT INFLAMMATION; RNA INTERFERENCE; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; DISEASE MODEL; GENETICS; HUMAN RESPIRATORY SYNCYTIAL VIRUS; IMMUNOLOGY; INFLAMMATION; MOUSE; PATHOLOGY; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; TH2 CELL;

ANIMALS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INFLAMMATION; INTERLEUKIN-4; MICE; MICE, INBRED BALB C; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; RNA, SMALL INTERFERING; RNA, VIRAL; TH2 CELLS;

EID: 84904408872     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2013.142     Document Type: Article

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