Age and sex inequalities in the prescription of evidence-based pharmacological therapy following an acute coronary syndrome in Portugal: The EURHOBOP study

European Journal of Preventive Cardiology

Volumn 21, Issue 11, 2014, Pages 1401-1408

  Pereira, Marta ^a   Araújo, Carla ^a   Dias, Paula ^b   Lunet, Nuno ^a   Subirana, Isaac ^c   Marrugat, Jaume ^c   Capewell, Simon ^d   Bennett, Kathleen ^e   Azevedo, Ana ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b Centro Hospitalar Universitário de São João   (Portugal)

^c INST MUNIC D INVESTIGACIO MEDICA   (Spain)

^d UNIVERSITY OF LIVERPOOL   (United Kingdom)

^e ST JAMES S HOSPITAL   (Ireland)

Author keywords

Acute coronary syndrome; age; inequalities; secondary prevention; sex

Indexed keywords

ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CLOPIDOGREL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; CARDIOVASCULAR AGENT;

ACUTE CORONARY SYNDROME; ADULT; AGE; AGED; ARTICLE; COHORT ANALYSIS; CORONARY ARTERY BYPASS SURGERY; DIABETES MELLITUS; EVIDENCE BASED PRACTICE; FEMALE; HEART INFARCTION; HEART LEFT BUNDLE BRANCH BLOCK; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; PERCUTANEOUS CORONARY INTERVENTION; PRESCRIPTION; RETROSPECTIVE STUDY; SECONDARY PREVENTION; SEX DIFFERENCE; SMOKING; ST SEGMENT ELEVATION; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; VERY ELDERLY; CLINICAL PRACTICE; CLINICAL TRIAL; COMPARATIVE STUDY; DRUG COMBINATION; DRUG USE; EVIDENCE BASED MEDICINE; HEALTH CARE DISPARITY; HEALTH CARE SURVEY; HOSPITAL DISCHARGE; MIDDLE AGED; MULTICENTER STUDY; MYOCARDIAL INFARCTION; PORTUGAL; PRACTICE GUIDELINE; PROCEDURES; RISK; RISK FACTOR; STATISTICAL MODEL; TIME; YOUNG ADULT;

ACUTE CORONARY SYNDROME; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CARDIOVASCULAR AGENTS; DRUG PRESCRIPTIONS; DRUG THERAPY, COMBINATION; DRUG UTILIZATION REVIEW; EVIDENCE-BASED MEDICINE; FEMALE; GUIDELINE ADHERENCE; HEALTH CARE SURVEYS; HEALTHCARE DISPARITIES; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; ODDS RATIO; PATIENT DISCHARGE; PHYSICIAN'S PRACTICE PATTERNS; PORTUGAL; PRACTICE GUIDELINES AS TOPIC; RETROSPECTIVE STUDIES; RISK FACTORS; SECONDARY PREVENTION; SEX FACTORS; TIME FACTORS; YOUNG ADULT;

EID: 84904391608     PISSN: 20474873     EISSN: 20474881     Source Type: Journal    
DOI: 10.1177/2047487313494580     Document Type: Article

References (28)

1. The global burden of disease, 2004 update. Geneva: WHO ; 2008
2. Óbitos (N.°) por Sexo e Causa de morte; Anual. Lisboa: Instituto Nacional de Estatística ; 2010
3. Hamm CW, Bassand JP, Agewall S, et al. ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: the Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J. 2011 ; 32: 2999-3054
4. Steg G, James SK, Atar D, et al. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC). Eur Heart J. 2012 ; 33: 2569-2619
5. Distribuição da população residente (%) por Grupo etário; Anual. Lisboa: Instituto Nacional de Estatística ; 2011
6. Fox KAA, Dabbous OH, Goldberg RJ, et al. Prediction of risk of death and myocardial infarction in the six months after presentation with acute coronary syndrome: prospective multinational observational study (GRACE). BMJ. 2006 ; 333: 1091-1091
7. Correia R Geographic and temporal variation of the procedures used in myocardial infarction. Porto: University of Porto, Medical School ; 2011
8. Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics-2012 update: a report from the American Heart Association. Circulation. 2012 ; 125: e2 - e220
9. Pereira M, Peleteiro B, Capewell S, et al. Changing patterns of cardiovascular diseases and cancer mortality in Portugal, 1980-2010. BMC Public Health. 2012 ; 12: 1126-1126
10. Anand SS, Xie CC, Mehta S, et al. Differences in the management and prognosis of women and men who suffer from acute coronary syndromes. J Am Coll Cardiol. 2005 ; 46: 1845-1851
11. Hasdai D, Porter A, Rosengren A, et al. Effect of gender on outcomes of acute coronary syndromes. Am J Cardiol. 2003 ; 91: 1466-1469, A6
12. Lee HY, Cooke CE, Robertson TA. Use of secondary prevention drug therapy in patients with acute coronary syndrome after hospital discharge. J Manag Care Pharm. 2008 ; 14: 271-280
13. Santos JF, Aguiar C, Gavina C, et al. Portuguese Registry of Acute Coronary Syndromes: seven years of activity. Rev Port Cardiol. 2009 ; 28: 1465-1500
14. Buch P, Rasmussen S, Gislason GH, et al. Temporal decline in the prognostic impact of a recurrent acute myocardial infarction 1985 to 2002. Heart. 2007 ; 93: 210-215
15. ISIS-4: a randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58,050 patients with suspected acute myocardial infarction. ISIS-4 (Fourth International Study of Infarct Survival) Collaborative Group. Lancet 1995; 345: 669-685.
16. Kotseva K, Wood D, De Backer G, et al. EUROASPIRE III: a survey on the lifestyle, risk factors and use of cardioprotective drug therapies in coronary patients from 22 European countries. Eur J Cardiovasc Prev Rehabil. 2009 ; 16: 121-137
17. Buja A, Boemo D, Furlan P, et al. Tackling inequalities: are secondary prevention therapies for reducing post-infarction mortality used without disparities?. Eur J Prev Cardiol. 2012 ;:
18. Halon DA, Adawi S, Dobrecky-Mery I, et al. Importance of increasing age on the presentation and outcome of acute coronary syndromes in elderly patients. J Am Coll Cardiol. 2004 ; 43: 346-352
19. Goldberg RJ, McCormick D, Gurwitz JH, et al. Age-related trends in short- and long-term survival after acute myocardial infarction: a 20-year population-based perspective (1975-1995). Am J Cardiol. 1998 ; 82: 1311-1317
20. Krumholz H, Radford M, Wang Y, et al. National use and effectiveness of beta-blockers for the treatment of elderly patients after acute myocardial infarction: national cooperative cardiovascular project. JAMA. 1998 ; 280: 623-629
21. Miettinen TA, Pyörälä K, Olsson AG, et al. Cholesterol-lowering therapy in women and elderly patients with myocardial infarction or angina pectoris: findings from the Scandinavian Simvastatin Survival Study (4S). Circulation. 1997 ; 96: 4211-4218
22. Avezum A, Makdisse M, Spencer F, et al. Impact of age on management and outcome of acute coronary syndrome: observations from the global registry of acute coronary events (GRACE). Am Heart J. 2005 ; 149: 67-73
23. Rosengren A, Wallentin L, Simoons M, et al. Age, clinical presentation, and outcome of acute coronary syndromes in the Euroheart acute coronary syndrome survey. Eur Heart J. 2006 ; 27: 789-795
24. Collinson J, Bakhai A, Flather MD, et al. The management and investigation of elderly patients with acute coronary syndromes without ST elevation: an evidence-based approach? Results of the Prospective Registry of Acute Ischaemic Syndromes in the United Kingdom (PRAIS-UK). Age Ageing. 2005 ; 34: 61-66
25. Yan AT, Yan RT, Tan M, et al. Optimal medical therapy at discharge in patients with acute coronary syndromes: temporal changes, characteristics, and 1-year outcome. Am Heart J. 2007 ; 154: 1108-1115
26. Hvelplund A, Galatius S, Madsen M, et al. Women with acute coronary syndrome are less invasively examined and subsequently less treated than men. Eur Heart J. 2010 ; 31: 684-690
27. Rosengren A, Wallentin L, K Gitt A, et al. Sex, age, and clinical presentation of acute coronary syndromes. Eur Heart J. 2004 ; 25: 663-670
28. Alfredsson J, Stenestrand U, Wallentin L, et al. Gender differences in management and outcome in non-ST-elevation acute coronary syndrome. Heart. 2007 ; 93: 1357-1362