The management and investigation of elderly patients with acute coronary syndromes without ST elevation: An evidence-based approach? Results of the prospective registry of acute ischaemic syndromes in the United Kingdom (PRAIS-UK)

Age and Ageing

Volumn 34, Issue 1, 2005, Pages 61-66

  Collinson, Julian ^a   Bakhai, Ameet ^a   Flather, Marcus D ^a   Fox, Keith A ^b  

^a ROYAL BROMPTON AND HAREFIELD NHS FOUNDATION TRUST   (United Kingdom)

^b ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

Author keywords

Acute coronary syndromes; Elderly; Epidemiology; Mortality; Treatment patterns

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; HEPARIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

AGED; ANGIOCARDIOGRAPHY; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DIABETES MELLITUS; DISEASE ASSOCIATION; ELECTROCARDIOGRAPHY; FEMALE; FOLLOW UP; GROUPS BY AGE; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART MUSCLE REVASCULARIZATION; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; ST SEGMENT; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TRANSLUMINAL CORONARY ANGIOPLASTY; UNITED KINGDOM;

AGE FACTORS; AGED; AGED, 80 AND OVER; ANGINA, UNSTABLE; CARDIOVASCULAR AGENTS; CORONARY ANGIOGRAPHY; ELECTROCARDIOGRAPHY; EVIDENCE-BASED MEDICINE; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; MYOCARDIAL REVASCULARIZATION; SURVIVAL RATE;

EID: 12144274675     PISSN: 00020729     EISSN: None     Source Type: Journal    
DOI: 10.1093/ageing/afh236     Document Type: Article

References (34)

1. Gutfinger DE, Ott RA, Miller M et al. Elderly patients receive less aggressive medical and invasive management of unstable angina: potential impact of practice guidelines. Arch Intern Med 1998; 158: 1113-20.
2. Shahi CN, Rathore SS, Wang Y et al. Quality of care among elderly patients hospitalized with unstable angina. Am Heart J 2001; 142: 263-70.
3. Gazes PC, Mobley EMJ, Faris HMJ, Duncan RC, Humphries GB. Preinfarction (unstable) angina - a prospective study - ten year follow up. Prognostic significance of electrocardiographic changes. Circulation 1973; 48: 331-7.
4. Mulcahy R, Al Awadhi AH, de Buitleor M, Tobin G, Johnson H, Contoy R. Natural history and prognosis of unstable angina. Am Heart J 1985; 109: 753-8.
5. Wilcox I, Freedman SB, Allman KC et al. Prognostic significance of a predischarge exercise test in risk stratification after unstable angina. J Cardiol 1991; 18: 677-83.
6. van Domburg RT, van Miltenburg-van Zijl AJ, Veerhoek RJ, Simoons ML. Unstable angina: good long-term outcome after a complicated early course. J Am Coll Cardiol 1998; 31: 1534-9.
7. Antiplatelet Trialists' Collaboration. Collaborative overview of randomised trials of antiplatelet therapy (Part 1 of 3): Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Br Med J 1994; 308: 81-106.
8. Théroux P, Waters D, Shiqiang Q, McCans J, de Guise P, Juneau M. Aspirin versus heparin to prevent myocardial infarction during the acute phase of unstable angina. Circulation 1993; 88: 2045-8.
9. Théroux P, Taeymans Y, Morissette D, Bosch X, Pelletier GB, Waters DD. A randomized study comparing propranolol and diltiazem in the treatment of unstable angina. J Am Coll Cardiol 1985; 5: 717-22.
10. Boden WE, O'Rourke RA, Crawford MH et al. Outcomes in patients with acute non-Q-wave myocardial infarction randomly assigned to an invasive as compared with a conservative management strategy. N Engl J Med 1998; 338: 1785-92.
11. Collinson J, Flather MD, Fox KAA, Findlay I, Rodrigues E, Dooley P, Ludman P, Adgey J, Bowker TJ, Mattu R. Clinical outcomes, risk stratification and practice patterns of unstable angina and myocardial infarction without ST elevation: Prospective Registry of Acute Ischaemic Syndromes in the UK (PRAIS-UK). Eur Heart J 2000; 21: 1450-7.
12. British Cardiac Society Guidelines and Medical Practice Committee and Royal College of Physicians Clinical Effectiveness and Evaluation Unit. Guidelines for the management of patients with acute coronary syndromes without persistent ECG ST segment elevation. Heart 2001 Feb; 85: 133-42.
13. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients with Unstable Angina). ACC/AHA Guidelines for the Management of Patients with Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction. J Am Coll Cardiol 2000; 36: 970-1062.
14. Bertrand ME, Simoons ML, Fox KA et al. Management of acute coronary syndromes in patients presenting without persistent ST elevation. Eur Heart J 2002; 23: 1809-40.
15. Barron HV, Bowlby LJ, Breen T, Rogers WJ, Canto JG, Zhang Y, Tiefenbrunn AJ, Weaver WD. Use of reperfusion therapy for acute myocardial infarction in the United States: data from the National Registry of Myocardial Infarction 2. Circulation 1998; 97: 1150-6.
16. FRagmin and Fast Revascularisation during InStability in Coronary artery disease Investigators. Invasive compared with non-invasive treatment in unstable coronary artery disease: FRISC II prospective randomised multicentre study. Lancet 1999 Aug 28; 354: 708-15.
17. Yusuf S, Flather M, Pogue J et al. Variations between countries in invasive cardiac procedures and outcomes in patients with suspected unstable angina or myocardial infarction without initial ST elevation. OASIS (Organisation to Assess Strategies for Ischaemic Syndromes) Registry Investigators. Lancet 1998; 352: 507-14.
18. Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomized placebo-controlled trial. Lancet 2002; 360: 7-22.
19. Shepherd J, Blauw GJ, Murphy MB et al. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomized controlled trial. Lancet 2002; 360: 1623-30.
20. Barker WH, Mullooly JP, Linton KL. Trends in hypertension prevalence, treatment, and control: in a well-defined older population. Hypertension 2000; 31 (1 Pt 2): 552-9.
21. Shibata MC, Flather MD, Bohm M et al. Study of the Effects of Nebivolol Intervention on Outcomes and Rehospitalisation in Seniors with Heart Failure (SENIORS). Rationale and design. Int J Cardiol. 2002; 86: 77-85.
22. Anonymous. The sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. Arch Intern Med 2000; 157: 2413-46.
23. Cannon CP, Weintraub WS, Demopoulos LA et al. Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein IIb/IIIa inhibitor tirofiban. N Engl J Med 2001; 344: 1879-87.
24. Chauhan MS, Kuntz RE, Cohen DJ et al. Coronary artery stenting in the aged. J Am Coll Cardiol 2001; 37: 856-62.
25. Thompson RC, Holmes DR Jr, Grill DE, Mock MB, Bailey KR. Changing outcome of angioplasty in the elderly. J Am Coll Cardiol 1996; 27: 8-14.
26. Kaul TK, Fields BL, Wyatt DA, Jones CR, Kahn DR. Angioplasty versus coronary artery bypass in octogenarians. Ann Thorac Surg 1994; 58: 1419-26.
27. Glower DD, Christopher TD, Milano CA et al. Performance status and outcome after coronary artery bypass grafting in persons aged 80 to 93 years. Am J Cardiol 1992; 70: 567-71.
28. de Jaegere P, de Feyter P, van Domburg R, Suryapranata H, van den Brand M, Serruys PW. Immediate and long term results of percutaneous coronary angioplasty in patients aged 70 and over. Br Heart J 1992; 67: 138-43.
29. Munoz JC, Alonso JJ, Duran JM et al. Coronary stent implantation in patients older than 75 years of age: clinical profile and initial and long-term (3 years) outcome. Am Heart J 2002; 143: 620-6.
30. Akins CW, Daggett WM, Vlahakes GJ, Hilgenberg AD, Torchiana DF, Madsen JC, Buckley MJ. Cardiac operations in patients 80 years old and older. Ann Thorac Surg 1997; 64: 606-14.
31. Bowling A, Bond M, McKee D et al. Equity in access to exercise tolerance testing, coronary angiography, and coronary artery bypass grafting by age, sex and clinical indications. Heart 2001; 85: 680-6.
32. Johnson PA, Goldman L, Orav EJ, Zhou L, Garcia T, Pearson SD, Lee TH. Gender differences in the management of acute chest pain. Support for the 'Yentl syndrome'. J Gen Intern Med 1996; 11: 209-17.
33. Roeters van Lennep JE, Zwinderman AH, Roeters van Lennep HW et al. Gender differences in diagnosis and treatment of coronary artery disease from 1981 to 1997. No evidence for the Yentl syndrome. Eur Heart J 2000; 21: 911-8.
34. Department of Health. National Service Framework for Older People. Modern Standards and Service Models. London: Department of Health, 2001.