Overlapping trisomies for human chromosome 21 orthologs produce similar effects on skull and brain morphology of Dp(16)1Yey and Ts65Dn mice

American Journal of Medical Genetics, Part A

Volumn 164, Issue 8, 2014, Pages 1981-1990

  Starbuck, John M ^a,c   Dutka, Tara ^b   Ratliff, Tabetha S ^b   Reeves, Roger H ^b   Richtsmeier, Joan T ^a,b  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INDIANA UNIVERSITY SCHOOL OF DENTISTRY   (United States)

Author keywords

Brain morphology; Craniofacial morphogenesis; Down syndrome; Gene dosage imbalance; Trisomy 21

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CELL DENSITY; CELL GRANULE; CEREBELLUM; CONTROLLED STUDY; CRANIOFACIAL MALFORMATION; CRANIOFACIAL MORPHOLOGY; DOWN SYNDROME; GENE DOSAGE; GENE LOCATION; GENETIC ANALYSIS; MICRO-COMPUTED TOMOGRAPHY; MORPHOLOGY; MOUSE; NEUROANATOMY; NONHUMAN; OPEN READING FRAME; ORTHOLOGY; PHENOTYPE; PRIORITY JOURNAL; PURKINJE CELL; QUANTITATIVE ANALYSIS; ANIMAL; BRAIN; DISEASE MODEL; GENETICS; HUMAN; METABOLISM; PATHOLOGY; SKULL;

ANIMALS; BRAIN; CEREBELLUM; CRANIOFACIAL ABNORMALITIES; DISEASE MODELS, ANIMAL; DOWN SYNDROME; HUMANS; MICE; PHENOTYPE; SKULL;

EID: 84904382695     PISSN: 15524825     EISSN: 15524833     Source Type: Journal    
DOI: 10.1002/ajmg.a.36594     Document Type: Article

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