Supplementating with dietary astaxanthin combined with collagen hydrolysate improves facial elasticity and decreases matrix metalloproteinase-1 and -12 expression: A comparative study with placebo

Journal of Medicinal Food

Volumn 17, Issue 7, 2014, Pages 810-816

  Yoon, Hyun Sun ^a,b   Cho, Hyun Hee ^a   Cho, Soyun ^a,b   Lee, Se Rah ^a   Shin, Mi Hee ^a   Chung, Jin Ho ^a  

^a Seoul National University   (South Korea)

^b Seoul National University Boramae Hospital   (South Korea)

Author keywords

anti aging; astaxanthin; collagen hydrolysate; photoaging

Indexed keywords

ASTAXANTHIN; COLLAGEN; COLLAGEN HYDROLYSATE; DNA; FIBRILLIN 1; INTERSTITIAL COLLAGENASE; MACROPHAGE ELASTASE; MESSENGER RNA; PLACEBO; PROCOLLAGEN C PROTEINASE; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; ANTIOXIDANT; COLLAGEN TYPE 1; FIBRILLIN; MMP1 PROTEIN, HUMAN; MMP12 PROTEIN, HUMAN; XANTHOPHYLL;

ADULT; ARTICLE; BUTTOCK; CASE REPORT; CONTROLLED STUDY; CUTANEOUS PARAMETERS; DIET SUPPLEMENTATION; DNA DAMAGE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; ELASTICITY; FACE; FEMALE; HUMAN; HYDRATION; MIDDLE AGED; NON INVASIVE PROCEDURE; PHOTOAGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RANDOMIZED CONTROLLED TRIAL; SKIN; SKIN WATER LOSS; TASTE; ULTRAVIOLET RADIATION; ASIAN CONTINENTAL ANCESTRY GROUP; COMPARATIVE STUDY; DRUG EFFECTS; GENETICS; METABOLISM; PATIENT COMPLIANCE; RADIATION RESPONSE;

ADULT; ANTIOXIDANTS; ASIAN CONTINENTAL ANCESTRY GROUP; COLLAGEN; COLLAGEN TYPE I; DIETARY SUPPLEMENTS; DNA DAMAGE; DOUBLE-BLIND METHOD; ELASTICITY; FEMALE; HUMANS; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 12; MICROFILAMENT PROTEINS; MIDDLE AGED; PATIENT COMPLIANCE; RNA, MESSENGER; SKIN; SKIN AGING; ULTRAVIOLET RAYS; XANTHOPHYLLS;

EID: 84904359566     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2013.3060     Document Type: Article

References (28)

1. Fisher GJ, Wang ZQ, Datta SC, Varani J, Kang S, Voorhees JJ: Pathophysiology of premature skin aging induced by ultraviolet light. N Engl J Med 1997;337:1419-1428. (Pubitemid 27497889)
2. Rabe JH, Mamelak AJ, McElgunn PJ, Morison WL, Sauder DN: Photoaging: mechanisms and repair. J Am Acad Dermatol 2006;55:1-19. (Pubitemid 43867014)
3. Seite S, Colige A, Deroanne C, et al.: Changes in matrix gene and protein expressions after single or repeated exposure to one minimal erythemal dose of solar-simulated radiation in human skin in vivo. Photochem Photobiol 2004;79:265-271.
4. Draelos ZD: Nutrition and enhancing youthful-appearing skin. Clin Dermatol 2010;28:400-408.
5. Darvin ME, Fluhr JW, Schanzer S, et al.: Dermal carotenoid level and kinetics after topical and systemic administration of antioxidants: enrichment strategies in a controlled in vivo study. J Dermatol Sci 2011;64:53-58.
6. Higuera-Ciapara I, Felix-Valenzuela L, Goycoolea FM: Astax-anthin: a review of its chemistry and applications. Crit Rev Food Sci Nutr 2006;46:185-196.
7. Miki W: Biological functions and activities of animal caroten-oids. Pure Appl Chem 1991;63:141-146.
8. Hou H, Li B, Zhang Z, et al.: Moisture absorption and retention properties, and activity in alleviating skin photodamage of collagen polypeptide from marine fish skin. Food Chem 2012;135: 1432-1439.
9. Saito M, Kiyose C, Higuchi T, Uchida N, Suzuki H: Effect of collagen hydrolysates from salmon and trout skins on the lipid profile in rats. J Agric Food Chem 2009;57:10477-10482.
10. Gómez-Guillén MC, Giménez B, López-Caballero ME, Montero MP: Functional and bioactive properties of collagen and gelatin from alternative sources: a review. Food Hydrocolloids 2011;25: 1813-1827.
11. Liang J, Pei X, Zhang Z, Wang N, Wang J, Li Y: The protective effects of long-term oral administration of marine collagen hy-drolysate from chum salmon on collagen matrix homeostasis in the chronological aged skin of Sprague-Dawley male rats. J Food Sci 2010;75:H230-H238.
12. Chung JH, Lee SH, Youn CS, et al.: Cutaneous photodamage in Koreans: influence of sex, sun exposure, smoking, and skin color. Arch Dermatol 2001;137:1043-1051. (Pubitemid 32756462)
13. Cho S, Lee DH, Won CH, et al.: Differential effects of low-dose and high-dose beta-carotene supplementation on the signs of photoaging and type I procollagen gene expression in human skin in vivo. Dermatology 2010;221:160-171.
14. Livak KJ, Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001;25:402-408. (Pubitemid 34164012)
15. Hardy G: Nutraceuticals and functional foods: introduction and meaning. Nutrition 2000;16:688-689. (Pubitemid 30445151)
16. Zague V: A new view concerning the effects of collagen hy-drolysate intake on skin properties. Arch Dermatol Res 2008; 300:479-483.
17. Kidd P: Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging potential. Altern Med Rev 2011;16:355-364.
18. Yoshida H, Yanai H, Ito K, et al.: Administration of natural as-taxanthin increases serum HDL-cholesterol and adiponectin in subjects with mild hyperlipidemia. Atherosclerosis 2010;209:520-523.
19. Lyons NM, O'Brien NM: Modulatory effects of an algal extract containing astaxanthin on UVA-irradiated cells in culture. J Dermatol Sci 2002;30:73-84. (Pubitemid 35287152)
20. Suganuma K, Nakajima H, Ohtsuki M, Imokawa G: Astax-anthin attenuates the UVA-induced up-regulation of matrix-metalloproteinase-1 and skin fibroblast elastase in human dermal fibroblasts. J Dermatol Sci 2010;58:136-142.
21. Hama S, Takahashi K, Inai Y, et al.: Protective effects of topical application of a poorly soluble antioxidant astaxanthin liposomal formulation on ultraviolet-induced skin damage. J Pharm Sci 2012;101:2909-2916.
22. Matsuda N, Koyama Y, Hosaka Y, et al.: Effects of ingestion of collagen peptide on collagen fibrils and glycosaminoglycans in the dermis. J Nutr Sci Vitaminol 2006;52:211-215. (Pubitemid 44196898)
23. Tominaga K, Hongo N, Karato M, Yamashita E: Cosmetic benefits of astaxanthin on humans subjects. Acta Biochim Pol 2012;59:43-47.
24. Oesser S, Adam M, Babel W, Seifert J: Oral administration of (14)C labeled gelatin hydrolysate leads to an accumulation of radioactivity in cartilage of mice (C57/BL). J Nutr 1999;129: 1891-1895. (Pubitemid 29468605)
25. Iwai K, Hasegawa T, Taguchi Y, et al.: Identification of food-derived collagen peptides in human blood after oral ingestion of gelatin hydrolysates. J Agric Food Chem 2005;53:6531-6536. (Pubitemid 41169409)
26. Mercke Odeberg J, Lignell A, Pettersson A, Hoglund P: Oral bioavailability of the antioxidant astaxanthin in humans is enhanced by incorporation of lipid based formulations. Eur J Pharm Sci 2003;19:299-304. (Pubitemid 36918423)
27. Ohara H, Ichikawa S, Matsumoto H, et al.: Collagen-derived dipeptide, proline-hydroxyproline, stimulates cell proliferation and hyaluronic acid synthesis in cultured human dermal fibro-blasts. J Dermatol 2010;37:330-338.
28. Williams S, Tamburic S, Stensvik H, Weber M: Changes in skin physiology and clinical appearance after microdroplet placement of hyaluronic acid in aging hands. J Cosmet Dermatol 2009;8: 216-225.