Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) contributes to a triple-negative test in preoperative screening of pancreatic cysts

Cancer Cytopathology

Volumn 122, Issue 6, 2014, Pages 412-419

  Wu, Roseann I ^a   Yoon, Won Jae ^a,b   Brugge, William R ^a   Mino Kenudson, Mari ^a   Pitman, Martha B ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Inje University College of Medicine   (South Korea)

Author keywords

Carcinoembryonic antigen; Cytopathology; Endoscopic ultrasound guided fine needle aspiration; Pancreatic cyst; Pancreatic neoplasms

Indexed keywords

CARCINOEMBRYONIC ANTIGEN;

ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CYST FLUID; CYTOLOGY; CYTOPATHOLOGY; ENDOSCOPIC ULTRASOUND GUIDED FINE NEEDLE BIOPSY; FOLLOW UP; HIGH RISK POPULATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; MAJOR CLINICAL STUDY; OUTCOME ASSESSMENT; PANCREAS CYST; PREDICTIVE VALUE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCREENING TEST;

CARCINOEMBRYONIC ANTIGEN; CYTOPATHOLOGY; ENDOSCOPIC ULTRASOUND-GUIDED FINE-NEEDLE ASPIRATION; PANCREATIC CYST; PANCREATIC NEOPLASMS;

CARCINOEMBRYONIC ANTIGEN; CYST FLUID; CYSTADENOCARCINOMA, MUCINOUS; ENDOSCOPIC ULTRASOUND-GUIDED FINE NEEDLE ASPIRATION; FOLLOW-UP STUDIES; HUMANS; MASS SCREENING; PANCREATIC CYST; PANCREATIC NEOPLASMS; RETROSPECTIVE STUDIES;

EID: 84904337520     PISSN: 1934662X     EISSN: 19346638     Source Type: Journal    
DOI: 10.1002/cncy.21385     Document Type: Article

References (39)

1. Fernandez-del Castillo C, Targarona J, Thayer SP, Rattner DW, Brugge WR, Warshaw AL. Incidental pancreatic cysts: clinicopathologic characteristics and comparison with symptomatic patients. Arch Surg. 2003;138:427-430; discussion 433-434
2. Canto MI, Hruban RH, Fishman EK, et al. Frequent detection of pancreatic lesions in asymptomatic high-risk individuals. Gastroenterology. 2012;142:796-804; quiz e14-e15
3. Laffan TA, Horton KM, Klein AP, et al. Prevalence of unsuspected pancreatic cysts on MDCT. AJR Am J Roentgenol. 2008;191:802-807
4. Lee KS, Sekhar A, Rofsky NM, Pedrosa I. Prevalence of incidental pancreatic cysts in the adult population on MR imaging. Am J Gastroenterol. 2010;105:2079-2084
5. Tanaka M, Chari S, Adsay V, et al. International Association of Pancreatology. International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas. Pancreatology. 2006;6:17-32
6. Tanaka M, Fernandez-del Castillo C, Adsay V, et al. International Association of Pancreatology. International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas. Pancreatology. 2012;12:183-197
7. Wong J, Weber J, Centeno BA, et al. High-grade dysplasia and adenocarcinoma are frequent in side-branch intraductal papillary mucinous neoplasm measuring less than 3 cm on endoscopic ultrasound. J Gastrointest Surg. 2013;17:78-85
8. Fritz S, Klauss M, Bergmann F, et al. Small (Sendai negative) branch-duct IPMNs: not harmless. Ann Surg. 2012;256:313-320
9. Pitman MB, Michaels PJ, Deshpande V, Brugge WR, Bounds BC. Cytological and cyst fluid analysis of small (< or 53 cm) branch duct intraductal papillary mucinous neoplasms adds value to patient management decisions. Pancreatology. 2008;8:277-284. (Pubitemid 351832481)
10. Pitman MB, Genevay M, Yaeger K, et al. High-grade atypical epithelial cells in pancreatic mucinous cysts are a more accurate predictor of malignancy than "positive" cytology. Cancer Cytopathol. 2010;118:434-440
11. Oppong K, Leeds J, Elamin K, Wadehra V, Charnley R, Nayar M. Utility of cyst fluid CEA cutoff of 192ng/mL in the diagnosis of mucinous cysts of the pancreas [abstract]. Gut. 2011;60(suppl 1):A80
12. Pitman MB, Centeno BA, Daglilar ES, Brugge WR, Mino- Kenudson M. Cytological criteria of high-grade epithelial atypia in the cyst fluid of pancreatic intraductal papillary mucinous neoplasms [published online ahead of print August 12, 2013]. Cancer Cytopathol. 2013
13. Pitman MB, Centeno BA, Genevay M, Fonseca R, Mino- Kenudson M. Grading epithelial atypia in endoscopic ultrasoundguided fine-needle aspiration of intraductal papillary mucinous neoplasms: An international interobserver concordance study [published online ahead of print July 23, 2013]. Cancer Cytopathol. 2013
14. Yoon WJ, Daglilar ES, Pitman MB, Brugge WR. Cystic pancreatic neuroendocrine tumors: endoscopic ultrasound and fine-needle aspiration characteristics. Endoscopy. 2013;45:189-194
15. Solomon D, Nayar R. The Bethesda System for Reporting Cervical Cytology: Definitions, Criteria, and Explanatory Notes. 2nd ed. New York: Springer; 2004
16. Khashab MA, Kim K, Lennon AM, et al. Should we do EUS/FNA on patients with pancreatic cysts? The incremental diagnostic yield of EUS over CT/MRI for prediction of cystic neoplasms. Pancreas. 2013;42:717-721
17. Owens CL, Vandenbussche CJ, Burroughs FH, Rosenthal DL. A review of reporting systems and terminology for urine cytology. Cancer Cytopathol. 2013;121:9-14
18. Jones C, Liu K, Hirschowitz S, Klipfel N, Layfield LJ. Concordance of histopathologic and cytologic grading in musculoskeletal sarcomas: can grades obtained from analysis of the fine-needle aspirates serve as the basis for therapeutic decisions? Cancer. 2002;96:83-91 (Pubitemid 34438648)
19. Emerson RE, Randolph ML, Cramer HM. Endoscopic ultrasoundguided fine-needle aspiration cytology diagnosis of intraductal papillary mucinous neoplasm of the pancreas is highly predictive of pancreatic neoplasia. Diagn Cytopathol. 2006;34:457-462
20. Layfield LJ, Cramer H. Fine-needle aspiration cytology of intraductal papillary-mucinous tumors: A retrospective analysis. Diagn Cytopathol. 2005;32:16-20 (Pubitemid 40024068)
21. Lee CJ, Scheiman J, Anderson MA, et al. Risk of malignancy in resected cystic tumors of the pancreas
22. Jang JY, Kim SW, Ahn YJ, et al. Multicenter analysis of clinicopathologic features of intraductal papillary mucinous tumor of the pancreas: is it possible to predict the malignancy before surgery? Ann Surg Oncol. 2005;12:124-132 (Pubitemid 40486620)
23. Sugiyama M, Izumisato Y, Abe N, Masaki T, Mori T, Atomi Y. Predictive factors for malignancy in intraductal papillary-mucinous tumours of the pancreas. Br J Surg. 2003;90:1244-1249 (Pubitemid 37330429)
24. Sadakari Y, Ienaga J, Kobayashi K, et al. Cyst size indicates malignant transformation in branch duct intraductal papillary mucinous neoplasm of the pancreas without mural nodules. Pancreas. 2010; 39:232-236
25. Spinelli KS, Fromwiller TE, Daniel RA, et al. Cystic pancreatic neoplasms: observe or operate. Ann Surg. 2004;239:651-657; discussion 657-659
26. Ono J, Yaeger KA, Genevay M, Mino-Kenudson M, Brugge WR, Pitman MB. Cytological analysis of small branch-duct intraductal papillary mucinous neoplasms provides a more accurate risk assessment of malignancy than symptoms [serial online]. Cytojournal. 2011;8:21
27. Sahani DV, Lin DJ, Venkatesan AM, et al. Multidisciplinary approach to diagnosis and management of intraductal papillary mucinous neoplasms of the pancreas. Clin Gastroenterol Hepatol. 2009;7:259-269
28. Sahani DV, Kadavigere R, Saokar A, Fernandez-del Castillo C, Brugge WR, Hahn PF. Cystic pancreatic lesions: A simple imagingbased classification system for guiding management. Radiographics. 2005;25:1471-1484 (Pubitemid 41695317)
29. Pitman MB, Deshpande V. Endoscopic ultrasound-guided fine needle aspiration cytology of the pancreas: A morphological and multimodal approach to the diagnosis of solid and cystic mass lesions. Cytopathology. 2007;18:331-347 (Pubitemid 350145655)
30. Frossard JL, Amouyal P, Amouyal G, et al. Performance of endosonography-guided fine needle aspiration and biopsy in the diagnosis of pancreatic cystic lesions. Am J Gastroenterol. 2003;98: 1516-1524 (Pubitemid 36875343)
31. Pais SA, Attasaranya S, Leblanc JK, Sherman S, Schmidt CM, DeWitt J. Role of endoscopic ultrasound in the diagnosis of intraductal papillary mucinous neoplasms: correlation with surgical histopathology. Clin Gastroenterol Hepatol. 2007;5:489-495 (Pubitemid 46575363)
32. Maire F, Couvelard A, Hammel P, et al. Intraductal papillary mucinous tumors of the pancreas: the preoperative value of cytologic and histopathologic diagnosis. Gastrointest Endosc. 2003;58: 701-706 (Pubitemid 37370483)
33. Repak R, Rejchrt S, Bartova J, Malirova E, Tycova V, Bures J. Endoscopic ultrasonography (EUS) and EUS-guided fine-needle aspiration with cyst fluid analysis in pancreatic cystic neoplasms. Hepatogastroenterology. 2009;56:629-635
34. Shin HJ, Lahoti S, Sneige N. Endoscopic ultrasound-guided fineneedle aspiration in 179 cases: the MD Anderson Cancer Center experience. Cancer. 2002 25;96:174-180 (Pubitemid 34640953)
35. Genevay M, Mino-Kenudson M, Yaeger K, et al. Cytology adds value to imaging studies for risk assessment of malignancy in pancreatic mucinous cysts. Ann Surg. 2011;254:977-983
36. Thosani N, Thosani S, Qiao W, Fleming JB, Bhutani MS, Guha S. Role of EUS-FNA-based cytology in the diagnosis of mucinous pancreatic cystic lesions: A systematic review and meta-analysis. Dig Dis Sci. 2010;55:2756-2766
37. Attasaranya S, Pais S, LeBlanc J, McHenry L, Sherman S, DeWitt JM. Endoscopic ultrasound-guided fine needle aspiration and cyst fluid analysis for pancreatic cysts. JOP. 2007;8:553-563 (Pubitemid 47455815)
38. Maker AV, Lee LS, Raut CP, Clancy TE, Swanson RS. Cytology from pancreatic cysts has marginal utility in surgical decision-making. Ann Surg Oncol. 2008;15:3187-3192
39. Pitman MB. Pancreatic cyst fluid triage: A critical component of the preoperative evaluation of pancreatic cysts. Cancer Cytopathol. 2013;121:57-60