Piezo1, a mechanically activated ion channel, is required for vascular development in mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 28, 2014, Pages 10347-10352

  Ranade, Sanjeev S ^a,b   Qiu, Zhaozhu ^a,b,c   Woo, Seung Hyun ^a,b   Hur, Sung Sik ^d,e   Murthy, Swetha E ^a,b   Cahalan, Stuart M ^a,b   Xu, Jie ^a,b,c   Mathur, Jayanti ^c   Bandell, Michael ^a,b,c   Coste, Bertrand ^a,b,f   Li, Yi Shuan J ^d,e   Chien, Shu ^d,e   Patapoutian, Ardem ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f University of Mediterranée   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ION CHANNEL; PIEZO 1 PROTEIN; UNCLASSIFIED DRUG;

ALLELE; ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; BLOOD FLOW; BLOOD VESSEL; CARDIOVASCULAR FUNCTION; CELL STRUCTURE; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENDOCARDIUM; ENDOTHELIUM CELL; EXON; FLOW CYTOMETRY; FLUORESCENCE; FORCE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTERNAL RIBOSOME ENTRY SITE; INTRON; MECHANICAL STIMULATION; MECHANOTRANSDUCTION; MOUSE; NONHUMAN; PERICARDIAL EFFUSION; PERICYTE; PREGNANCY; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHEAR STRESS; SMOOTH MUSCLE FIBER; STRESS FIBER; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

ANIMALS; CARDIOVASCULAR SYSTEM; EMBRYONIC DEVELOPMENT; ENDOTHELIAL CELLS; ION CHANNELS; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, TRANSGENIC;

EID: 84904334120     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1409233111     Document Type: Article

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