Hydrogen peroxide metabolism and sensing in human erythrocytes: A validated kinetic model and reappraisal of the role of peroxiredoxin II

Free Radical Biology and Medicine

Volumn 74, Issue , 2014, Pages 35-49

  Benfeitas, Rui ^a,b   Selvaggio, Gianluca ^a   Antunes, Fernando ^c   Coelho, Pedro M B M ^a   Salvador, Armindo ^a,d  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF LISBON   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Free radicals; Peroxiredoxin sulfinylation; Quantitative redox biology; Redox signaling; Systems biology; Thioredoxin

Indexed keywords

CATALASE; DITHIOL DERIVATIVE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; MONOMER; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PEROXIDASE; PEROXIREDOXIN 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THIOREDOXIN; THIOREDOXIN REDUCTASE; PEROXIREDOXIN; PRDX2 PROTEIN, HUMAN;

ARTICLE; ENZYME ACTIVITY; ENZYME INHIBITION; ERYTHROCYTE; HEMOLYSATE; HUMAN; HUMAN CELL; KINETICS; OXIDATION REDUCTION POTENTIAL; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STEADY STATE; STRESS; BIOLOGICAL MODEL; BIOLOGY; METABOLISM; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PHYSIOLOGY; SIGNAL TRANSDUCTION;

CATALASE; COMPUTATIONAL BIOLOGY; ERYTHROCYTES; HUMANS; HYDROGEN PEROXIDE; KINETICS; MODELS, BIOLOGICAL; NADP; OXIDATION-REDUCTION; OXIDATIVE STRESS; PEROXIREDOXINS; SIGNAL TRANSDUCTION;

EID: 84904329372     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.06.007     Document Type: Article

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