Acquisition of aberrant DNA methylation is associated with frailty in the very old: Findings from the Newcastle 85+ Study

Biogerontology

Volumn 15, Issue 4, 2014, Pages 317-328

  Collerton, Joanna ^a   Gautrey, Hannah E ^a   Van Otterdijk, Sanne D ^a   Davies, Karen ^a   Martin Ruiz, Carmen ^a   Von Zglinicki, Thomas ^a   Kirkwood, Thomas B L ^a   Jagger, Carol ^a   Mathers, John C ^a   Strathdee, Gordon ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Ageing; CpG island; DNA methylation; Epigenetics; Frailty

Indexed keywords

AGED; ARTICLE; BODY MASS; CHRONIC DISEASE; COGNITION; COHORT ANALYSIS; CONTROLLED STUDY; CPG ISLAND; CROSS-SECTIONAL STUDY; DIABETES MELLITUS; DISABILITY SEVERITY; DNA METHYLATION; DNA MODIFICATION; FEMALE; FRAIL ELDERLY; GENE LOCUS; GERIATRIC PATIENT; HOUSING; HUMAN; MAJOR CLINICAL STUDY; MALE; MINI MENTAL STATE EXAMINATION; PRIORITY JOURNAL; PROMOTER REGION; PYROSEQUENCING; QUANTITATIVE ANALYSIS; RESIDENTIAL CARE; POLYMERASE CHAIN REACTION; VERY ELDERLY;

AGED; AGED, 80 AND OVER; CPG ISLANDS; DNA METHYLATION; FRAIL ELDERLY; HUMANS; POLYMERASE CHAIN REACTION;

EID: 84904327454     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-014-9500-9     Document Type: Article

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