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Volumn 14, Issue 9, 2014, Pages

Autologous bone marrow transplantation for the treatment of multiple sclerosis

Author keywords

Autoimmunity; Autologous Hematopoietic stem cell transplantation; Cell therapy; Immunosuppression; Multiple Sclerosis; Multiple sclerosis treatment

Indexed keywords

ARTICLE; AUTOIMMUNE THYROIDITIS; AUTOLOGOUS BONE MARROW TRANSPLANTATION; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; CLINICAL EFFECTIVENESS; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FEASIBILITY STUDY; HERPES SIMPLEX; HERPES ZOSTER; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; MULTIPLE SCLEROSIS; NONHUMAN; PATIENT SAFETY; PATIENT SELECTION; PROGRESSION FREE SURVIVAL; SEPSIS; STEM CELL MOBILIZATION; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE; URINARY TRACT INFECTION; VIRUS REACTIVATION; AUTOTRANSPLANTATION; BONE MARROW TRANSPLANTATION; PROCEDURES;

EID: 84904271569     PISSN: 15284042     EISSN: 15346293     Source Type: Journal    
DOI: 10.1007/s11910-014-0478-0     Document Type: Article
Times cited : (29)

References (50)
  • 2
    • 33244466021 scopus 로고    scopus 로고
    • Natural history of multiple sclerosis: A unifying concept
    • DOI 10.1093/brain/awl007
    • Confavreux C, Vukusic S. Natural history of multiple sclerosis: a unifying concept. Brain. 2006;129(Pt 3):606-16. doi:10.1093/brain/awl007. (Pubitemid 43278223)
    • (2006) Brain , vol.129 , Issue.3 , pp. 606-616
    • Confavreux, C.1    Vukusic, S.2
  • 3
    • 0032881051 scopus 로고    scopus 로고
    • The natural history of multiple sclerosis: A geographically based study. 7. Progressive-relapsing and relapsing-progressive multiple sclerosis: A re-evaluation
    • Kremenchutzky M, Cottrell D, Rice G, Hader W, Baskerville J, Koopman W, et al. The natural history of multiple sclerosis: a geographically based study. 7. Progressive-relapsing and relapsing-progressive multiple sclerosis: a re-evaluation. Brain. 1999;122(Pt 10):1941-50.
    • (1999) Brain , vol.122 , Issue.PART 10 , pp. 1941-1950
    • Kremenchutzky, M.1    Cottrell, D.2    Rice, G.3    Hader, W.4    Baskerville, J.5    Koopman, W.6
  • 4
    • 84875244645 scopus 로고    scopus 로고
    • Communication between pathogenic T-cells and myeloid cells in neuroinflammatory disease
    • doi:10.1016/j.it.2012.09.007
    • Codarri L, Greter M, Becher B. Communication between pathogenic T-cells and myeloid cells in neuroinflammatory disease. Trends Immunol. 2013;34(3):114-9. doi:10.1016/j.it.2012.09.007.
    • (2013) Trends Immunol , vol.34 , Issue.3 , pp. 114-119
    • Codarri, L.1    Greter, M.2    Becher, B.3
  • 5
    • 53649109121 scopus 로고    scopus 로고
    • Induction vs escalating therapy in multiple sclerosis: Practical implications
    • doi:10.1007/s10072-008-0954-x
    • Comi G. Induction vs escalating therapy in multiple sclerosis: practical implications. Neurol Sci. 2008;29 Suppl 2:S253-5. doi:10.1007/s10072-008-0954-x .
    • (2008) Neurol Sci , vol.29 , Issue.SUPPL. 2
    • Comi, G.1
  • 6
    • 55149114851 scopus 로고    scopus 로고
    • Haematopoietic stem cell transplantation for autoimmune disorders
    • doi:10.1097/MOH.0b013e3283136700
    • Saccardi R, Di Gioia M, Bosi A. Haematopoietic stem cell transplantation for autoimmune disorders. Curr Opin Hematol. 2008;15(6):594-600. doi:10.1097/MOH.0b013e3283136700.
    • (2008) Curr Opin Hematol , vol.15 , Issue.6 , pp. 594-600
    • Saccardi, R.1    Di Gioia, M.2    Bosi, A.3
  • 7
    • 84862184679 scopus 로고    scopus 로고
    • Haematopoietic SCT in severe autoimmune diseases: Updated guidelines of the European Group for Blood and Marrow Transplantation
    • doi:10.1038/bmt.2011.185. Current guidelines for HSCT in autoimmune disorders
    • •• Snowden JA, Saccardi R, Allez M, Ardizzone S, Arnold R, Cervera R, et al. Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant. 2012;47(6):770-90. doi:10.1038/bmt.2011.185. Current guidelines for HSCT in autoimmune disorders.
    • (2012) Bone Marrow Transplant , vol.47 , Issue.6 , pp. 770-790
    • Snowden, J.A.1    Saccardi, R.2    Allez, M.3    Ardizzone, S.4    Arnold, R.5    Cervera, R.6
  • 8
    • 0034081050 scopus 로고    scopus 로고
    • Stem cell transplantation in experimental models of autoimmune disease
    • van Bekkum DW. Stem cell transplantation in experimental models of autoimmune disease. J Clin Immunol. 2000;20(1):10-6.
    • (2000) J Clin Immunol , vol.20 , Issue.1 , pp. 10-16
    • Van Bekkum, D.W.1
  • 9
    • 16544388850 scopus 로고    scopus 로고
    • Coincidental autoimmune disease in patients transplanted for conventional indications
    • DOI 10.1016/j.beha.2004.04.004, PII S1521692604000179
    • Marmont AM. Stem cell transplantation for autoimmune disorders. Coincidental autoimmune disease in patients transplanted for conventional indications. Best Pract Res Clin Hematol. 2004;17(2): 223-32. doi:10.1016/j.beha.2004.04.004. (Pubitemid 39145095)
    • (2004) Best Practice and Research: Clinical Haematology , vol.17 , Issue.2 , pp. 223-232
    • Marmont, A.M.1
  • 10
    • 0032055153 scopus 로고    scopus 로고
    • Effect of disease stage on clinical outcome after syngeneic bone marrow transplantation for relapsing experimental autoimmune encephalomyelitis
    • Burt RK, Padilla J, Begolka WS, Canto MC, Miller SD. Effect of disease stage on clinical outcome after syngeneic bone marrow transplantation for relapsing experimental autoimmune encephalomyelitis. Blood. 1998;91(7):2609-16. (Pubitemid 28155538)
    • (1998) Blood , vol.91 , Issue.7 , pp. 2609-2616
    • Burt, R.K.1    Padilla, J.2    Begolka, W.S.3    Dal, C.M.C.4    Miller, S.D.5
  • 11
    • 84878303057 scopus 로고    scopus 로고
    • Autologous hematopoietic stem cell transplantation as a treatment option for aggressive multiple sclerosis
    • doi:10.1007/s11940-013-0234-9
    • Pfender N, Saccardi R, Martin R. Autologous hematopoietic stem cell transplantation as a treatment option for aggressive multiple sclerosis. Curr Treat Options Neurol. 2013;15(3):270-80. doi:10.1007/s11940-013-0234-9.
    • (2013) Curr Treat Options Neurol , vol.15 , Issue.3 , pp. 270-280
    • Pfender, N.1    Saccardi, R.2    Martin, R.3
  • 13
    • 84876479682 scopus 로고    scopus 로고
    • Diminished Th17 (not Th1) responses underlie multiple sclerosis disease abrogation after hematopoietic stem cell transplantation
    • doi:10.1002/ana.23784. Observation that HSCT selectively reduces Th17 in MS
    • • Darlington PJ, Touil T, Doucet JS, Gaucher D, Zeidan J, Gauchat D, et al. Diminished Th17 (not Th1) responses underlie multiple sclerosis disease abrogation after hematopoietic stem cell transplantation. Ann Neurol. 2013;73(3):341-54. doi:10.1002/ana.23784. Observation that HSCT selectively reduces Th17 in MS.
    • (2013) Ann Neurol , vol.73 , Issue.3 , pp. 341-354
    • Darlington, P.J.1    Touil, T.2    Doucet, J.S.3    Gaucher, D.4    Zeidan, J.5    Gauchat, D.6
  • 14
    • 76749085197 scopus 로고    scopus 로고
    • T-cell clones persisting in the circulation after autologous hematopoietic SCT are undetectable in the peripheral CD34+ selected graft
    • doi:10.1038/bmt.2009.139
    • Dubinsky AN, Burt RK, Martin R, Muraro PA. T-cell clones persisting in the circulation after autologous hematopoietic SCT are undetectable in the peripheral CD34+ selected graft. Bone Marrow Transplant. 2010;45(2):325-31. doi:10.1038/bmt.2009.139.
    • (2010) Bone Marrow Transplant , vol.45 , Issue.2 , pp. 325-331
    • Dubinsky, A.N.1    Burt, R.K.2    Martin, R.3    Muraro, P.A.4
  • 15
    • 84896775850 scopus 로고    scopus 로고
    • T-cell repertoire following autologous stem cell transplantation for multiple sclerosis
    • doi:10.1172/JCI71691
    • Muraro PA, Robins H, Malhotra S, Howell M, Phippard D, Desmarais C, et al. T-cell repertoire following autologous stem cell transplantation for multiple sclerosis. J Clin Invest. 2014;124(3):1168-72. doi:10.1172/JCI71691.
    • (2014) J Clin Invest , vol.124 , Issue.3 , pp. 1168-1172
    • Muraro, P.A.1    Robins, H.2    Malhotra, S.3    Howell, M.4    Phippard, D.5    Desmarais, C.6
  • 16
    • 84883442367 scopus 로고    scopus 로고
    • Nonmyeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T-cells in multiple sclerosis
    • doi:10.1093/brain/awt182. Mechanism of action of nonmyeloablative conditioning in HSCT for MS
    • • Abrahamsson SV, Angelini DF, Dubinsky AN, Morel E, Oh U, Jones JL, et al. Nonmyeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T-cells in multiple sclerosis. Brain. 2013;136(Pt 9):2888-903. doi:10.1093/brain/awt182. Mechanism of action of nonmyeloablative conditioning in HSCT for MS.
    • (2013) Brain , vol.136 , Issue.PART 9 , pp. 2888-2903
    • Abrahamsson, S.V.1    Angelini, D.F.2    Dubinsky, A.N.3    Morel, E.4    Oh, U.5    Jones, J.L.6
  • 17
    • 2442504914 scopus 로고    scopus 로고
    • Characteristics of T-cell receptor repertoire and myelin-reactive T cells reconstituted from autologous haematopoietic stem-cell grafts in multiple sclerosis
    • DOI 10.1093/brain/awh117
    • Sun W, Popat U, Hutton G, Zang YC, Krance R, Carrum G, et al. Characteristics of T-cell receptor repertoire and myelin-reactive Tcells reconstituted from autologous haematopoietic stem-cell grafts in multiple sclerosis. Brain. 2004;127(Pt 5):996-1008. doi:10.1093/brain/awh117. (Pubitemid 38623037)
    • (2004) Brain , vol.127 , Issue.5 , pp. 996-1008
    • Sun, W.1    Popat, U.2    Hutton, G.3    Zang, Y.C.Q.4    Krance, R.5    Carrum, G.6    Land, G.A.7    Heslop, H.8    Brenner, M.9    Zhang, J.Z.10
  • 20
    • 77953635372 scopus 로고    scopus 로고
    • Neuroinflammation and demyelination in multiple sclerosis after allogeneic hematopoietic stem cell transplantation
    • doi:10.1001/archneurol.2010.117
    • Lu JQ, Joseph JT, Nash RA, Storek J, Stevens AM, Metz LM, et al. Neuroinflammation and demyelination in multiple sclerosis after allogeneic hematopoietic stem cell transplantation. Arch Neurol. 2010;67(6):716-22. doi:10.1001/archneurol.2010.117.
    • (2010) Arch Neurol , vol.67 , Issue.6 , pp. 716-722
    • Lu, J.Q.1    Joseph, J.T.2    Nash, R.A.3    Storek, J.4    Stevens, A.M.5    Metz, L.M.6
  • 21
    • 58449095241 scopus 로고    scopus 로고
    • Continued disease activity in a patient with multiple sclerosis after allogeneic hematopoietic cell transplantation
    • doi:10.1001/archneurol.2008.522
    • Lu JQ, Storek J, Metz L, Yong VW, Stevens AM, Nash RA, et al. Continued disease activity in a patient with multiple sclerosis after allogeneic hematopoietic cell transplantation. Arch Neurol. 2009;66(1):116-20. doi:10.1001/archneurol.2008.522.
    • (2009) Arch Neurol , vol.66 , Issue.1 , pp. 116-120
    • Lu, J.Q.1    Storek, J.2    Metz, L.3    Yong, V.W.4    Stevens, A.M.5    Nash, R.A.6
  • 22
    • 0030714110 scopus 로고    scopus 로고
    • Peripheral blood stem cell transplantation in the treatment of progressive multiple sclerosis: First results of a pilot study
    • Fassas A, Anagnostopoulos A, Kazis A, Kapinas K, Sakellari I, Kimiskidis V, et al. Peripheral blood stem cell transplantation in the treatment of progressive multiple sclerosis: first results of a pilot study. Bone Marrow Transplant. 1997;20(8):631-8. doi:10.1038/sj.bmt.1700944. (Pubitemid 27477575)
    • (1997) Bone Marrow Transplantation , vol.20 , Issue.8 , pp. 631-638
    • Fassas, A.1    Anagnostopoulos, A.2    Kazis, A.3    Kapinas, K.4    Sakellari, I.5    Kimiskidis, V.6    Tsompanakou, A.7
  • 24
    • 0141593519 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation for progressive multiple sclerosis: Failure of a total body irradiation-based conditioning regimen to prevent disease progression in patients with high disability scores
    • DOI 10.1182/blood-2003-03-0877
    • Burt RK, Cohen BA, Russell E, Spero K, Joshi A, Oyama Y, et al. Hematopoietic stem cell transplantation for progressive multiple sclerosis: failure of a total body irradiation-based conditioning regimen to prevent disease progression in patients with high disability scores. Blood. 2003;102(7):2373-8. doi:10.1182/blood-2003-03-0877. (Pubitemid 37193572)
    • (2003) Blood , vol.102 , Issue.7 , pp. 2373-2378
    • Burt, R.K.1    Cohen, B.A.2    Russell, E.3    Spero, K.4    Joshi, A.5    Oyama, Y.6    Karpus, W.J.7    Luo, K.8    Jovanovic, B.9    Traynor, A.10    Karlin, K.11    Stefoski, D.12    Burns, W.H.13
  • 28
    • 0034576841 scopus 로고    scopus 로고
    • Peripheral blood stem cell transplantation in multiple sclerosis with busulfan and cyclophosphamide conditioning: Report of toxicity and immunological monitoring
    • Openshaw H, Lund BT, Kashyap A, Atkinson R, Sniecinski I, Weiner LP, et al. Peripheral blood stem cell transplantation in multiple sclerosis with busulfan and cyclophosphamide conditioning: report of toxicity and immunological monitoring. Biol Blood Marrow Transplant. 2000;6(5A):563-75.
    • (2000) Biol Blood Marrow Transplant , vol.6 , Issue.5 , pp. 563-575
    • Openshaw, H.1    Lund, B.T.2    Kashyap, A.3    Atkinson, R.4    Sniecinski, I.5    Weiner, L.P.6
  • 30
    • 84867405187 scopus 로고    scopus 로고
    • Autologous hematopoietic stem cell transplantation with reduced-intensity conditioning in multiple sclerosis
    • doi:10.1016/j.exphem.2012.07.003
    • Shevchenko JL, Kuznetsov AN, Ionova TI, Melnichenko VY, Fedorenko DA, Kartashov AV, et al. Autologous hematopoietic stem cell transplantation with reduced-intensity conditioning in multiple sclerosis. Exp Hematol. 2012;40(11):892-8. doi:10.1016/j.exphem.2012.07.003.
    • (2012) Exp Hematol , vol.40 , Issue.11 , pp. 892-898
    • Shevchenko, J.L.1    Kuznetsov, A.N.2    Ionova, T.I.3    Melnichenko, V.Y.4    Fedorenko, D.A.5    Kartashov, A.V.6
  • 31
    • 47149098599 scopus 로고    scopus 로고
    • High-dose immunosuppressive therapy with autologous hematopoietic stem cell transplantation as a treatment option in multiple sclerosis
    • doi:10.1016/j.exphem.2008.03.001
    • Shevchenko YL, Novik AA, Kuznetsov AN, Afanasiev BV, Lisukov IA, Kozlov VA, et al. High-dose immunosuppressive therapy with autologous hematopoietic stem cell transplantation as a treatment option in multiple sclerosis. Exp Hematol. 2008;36(8):922-8. doi:10.1016/j.exphem.2008.03.001.
    • (2008) Exp Hematol , vol.36 , Issue.8 , pp. 922-928
    • Shevchenko, Y.L.1    Novik, A.A.2    Kuznetsov, A.N.3    Afanasiev, B.V.4    Lisukov, I.A.5    Kozlov, V.A.6
  • 32
    • 84861811380 scopus 로고    scopus 로고
    • Autologous haematopoietic stem cell transplantation with an intermediate intensity conditioning regimen in multiple sclerosis: The Italian multi-center experience
    • doi:10.1177/1352458511429320. Italian study of autologous HSCT in MS with BEAM/ATG conditioning regimen
    • • Mancardi GL, Sormani MP, Di Gioia M, Vuolo L, Gualandi F, Amato MP, et al. Autologous haematopoietic stem cell transplantation with an intermediate intensity conditioning regimen in multiple sclerosis: the Italian multi-center experience. Mult Scler. 2012;18(6):835- 42. doi:10.1177/ 1352458511429320. Italian study of autologous HSCT in MS with BEAM/ATG conditioning regimen.
    • (2012) Mult Scler , vol.18 , Issue.6 , pp. 835-842
    • Mancardi, G.L.1    Sormani, M.P.2    Di Gioia, M.3    Vuolo, L.4    Gualandi, F.5    Amato, M.P.6
  • 33
    • 84908335130 scopus 로고    scopus 로고
    • Autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis: The Swedish experience
    • doi:10.1136/jnnp-2013-307207
    • Burman J, Iacobaeus E, Svenningsson A, Lycke J, Gunnarsson M, Nilsson P, et al. Autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis: the Swedish experience. J Neurol Neurosurg Psychiatry. 2014. doi:10.1136/jnnp-2013-307207.
    • (2014) J Neurol Neurosurg Psychiatry
    • Burman, J.1    Iacobaeus, E.2    Svenningsson, A.3    Lycke, J.4    Gunnarsson, M.5    Nilsson, P.6
  • 34
    • 60049083956 scopus 로고    scopus 로고
    • Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: A phase I/ II study
    • doi:10.1016/S1474-4422(09)70017-1
    • Burt RK, Loh Y, Cohen B, Stefoski D, Balabanov R, Katsamakis G, et al. Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: a phase I/ II study. Lancet Neurol. 2009;8(3):244-53. doi:10.1016/S1474-4422(09)70017-1.
    • (2009) Lancet Neurol , vol.8 , Issue.3 , pp. 244-253
    • Burt, R.K.1    Loh, Y.2    Cohen, B.3    Stefoski, D.4    Balabanov, R.5    Katsamakis, G.6
  • 35
    • 84863984951 scopus 로고    scopus 로고
    • Longterm efficacy of autologous haematopoietic stem cell transplantation in multiple sclerosis at a single institution in China
    • doi:10.1007/s10072-011-0859-y
    • Chen B, Zhou M, Ouyang J, Zhou R, Xu J, Zhang Q, et al. Longterm efficacy of autologous haematopoietic stem cell transplantation in multiple sclerosis at a single institution in China. Neurol Sci. 2012;33(4):881-6. doi:10.1007/s10072-011-0859-y.
    • (2012) Neurol Sci , vol.33 , Issue.4 , pp. 881-886
    • Chen, B.1    Zhou, M.2    Ouyang, J.3    Zhou, R.4    Xu, J.5    Zhang, Q.6
  • 36
    • 59349089705 scopus 로고    scopus 로고
    • Early highly aggressive MS successfully treated by hematopoietic stem cell transplantation
    • doi:10.1177/1352458508096875
    • Fagius J, Lundgren J, Oberg G. Early highly aggressive MS successfully treated by hematopoietic stem cell transplantation. Mult Scler. 2009;15(2):229-37. doi:10.1177/1352458508096875.
    • (2009) Mult Scler , vol.15 , Issue.2 , pp. 229-237
    • Fagius, J.1    Lundgren, J.2    Oberg, G.3
  • 37
    • 33751431058 scopus 로고    scopus 로고
    • Clinical outcomes after autologous haematopoietic stem cell transplantation in patients with progressive multiple sclerosis
    • Xu J, Ji BX, Su L, Dong HQ, Sun XJ, Liu CY. Clinical outcomes after autologous haematopoietic stemcell transplantation in patients with progressive multiple sclerosis. Chin Med J (Engl). 2006;119(22):1851-5. (Pubitemid 44816860)
    • (2006) Chinese Medical Journal , vol.119 , Issue.22 , pp. 1851-1855
    • Xu, J.1    Ji, B.-X.2    Su, L.3    Dong, H.-Q.4    Sun, X.-J.5    Liu, C.-Y.6
  • 38
    • 77953735863 scopus 로고    scopus 로고
    • High-dose immunoablation with autologous haematopoietic stem cell transplantation in aggressive multiple sclerosis: A single center 10-year experience
    • doi:10.1177/1352458510364538
    • Krasulova E, Trneny M, Kozak T, Vackova B, Pohlreich D, Kemlink D, et al. High-dose immunoablation with autologous haematopoietic stem cell transplantation in aggressive multiple sclerosis: a single center 10-year experience. Mult Scler. 2010;16(6):685-93. doi:10.1177/1352458510364538.
    • (2010) Mult Scler , vol.16 , Issue.6 , pp. 685-693
    • Krasulova, E.1    Trneny, M.2    Kozak, T.3    Vackova, B.4    Pohlreich, D.5    Kemlink, D.6
  • 39
    • 76749166185 scopus 로고    scopus 로고
    • Brazilian experience with two conditioning regimens in patients with multiple sclerosis: BEAM/ horse ATG and CY/rabbit ATG
    • doi:10.1038/bmt.2009.127
    • Hamerschlak N, Rodrigues M, Moraes DA, Oliveira MC, Stracieri AB, Pieroni F, et al. Brazilian experience with two conditioning regimens in patients with multiple sclerosis: BEAM/ horse ATG and CY/rabbit ATG. Bone Marrow Transplant. 2010;45(2):239-48. doi:10.1038/bmt.2009.127.
    • (2010) Bone Marrow Transplant , vol.45 , Issue.2 , pp. 239-248
    • Hamerschlak, N.1    Rodrigues, M.2    Moraes, D.A.3    Oliveira, M.C.4    Stracieri, A.B.5    Pieroni, F.6
  • 41
    • 84861802589 scopus 로고    scopus 로고
    • A prospective, randomized, controlled trial of autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis: A position paper
    • doi:10.1177/1352458512438454. Proposed indications for HSCT in MS patients: patient's selection, procedures, and outcome assessment
    • •• Saccardi R, Freedman MS, Sormani MP, Atkins H, Farge D, Griffith LM, et al. A prospective, randomized, controlled trial of autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis: a position paper.Mult Scler. 2012;18(6):825-34. doi:10.1177/1352458512438454. Proposed indications for HSCT in MS patients: patient's selection, procedures, and outcome assessment.
    • (2012) Mult Scler , vol.18 , Issue.6 , pp. 825-834
    • Saccardi, R.1    Freedman, M.S.2    Sormani, M.P.3    Atkins, H.4    Farge, D.5    Griffith, L.M.6
  • 43
    • 79953208669 scopus 로고    scopus 로고
    • Long-term results of stem cell transplantation for MS: A single-center experience
    • doi:10.1212/WNL.0b013e318211c537. Outcome of HSCT in MS patients after a median follow-up of 11 years
    • •• Fassas A, Kimiskidis VK, Sakellari I, Kapinas K, Anagnostopoulos A, Tsimourtou V, et al. Long-term results of stem cell transplantation for MS: a single-center experience. Neurology. 2011;76(12): 1066-70. doi:10.1212/WNL.0b013e318211c537. Outcome of HSCT in MS patients after a median follow-up of 11 years.
    • (2011) Neurology , vol.76 , Issue.12 , pp. 1066-1070
    • Fassas, A.1    Kimiskidis, V.K.2    Sakellari, I.3    Kapinas, K.4    Anagnostopoulos, A.5    Tsimourtou, V.6
  • 44
    • 84863727030 scopus 로고    scopus 로고
    • Autologous hematopoietic cell transplantation following high-dose immunosuppressive therapy for advanced multiple sclerosis: Long-term results
    • doi:10.1038/bmt.2011.208
    • Bowen JD, Kraft GH, Wundes A, Guan Q, Maravilla KR, Gooley TA, et al. Autologous hematopoietic cell transplantation following high-dose immunosuppressive therapy for advanced multiple sclerosis: long-term results. Bone Marrow Transplant. 2012;47(7):946-51. doi:10.1038/bmt.2011.208.
    • (2012) Bone Marrow Transplant , vol.47 , Issue.7 , pp. 946-951
    • Bowen, J.D.1    Kraft, G.H.2    Wundes, A.3    Guan, Q.4    Maravilla, K.R.5    Gooley, T.A.6
  • 49
    • 79951548112 scopus 로고    scopus 로고
    • Autologous hematopoietic cell transplantation for multiple sclerosis: A systematic review
    • doi:10.1177/1352458510383609. An updated review and meta-analysis of autologous HSCT studies in MS
    • • Reston JT, Uhl S, Treadwell JR, Nash RA, Schoelles K. Autologous hematopoietic cell transplantation for multiple sclerosis: a systematic review. Mult Scler. 2011;17(2):204-13. doi:10.1177/1352458510383609. An updated review and meta-analysis of autologous HSCT studies in MS.
    • (2011) Mult Scler , vol.17 , Issue.2 , pp. 204-213
    • Reston, J.T.1    Uhl, S.2    Treadwell, J.R.3    Nash, R.A.4    Schoelles, K.5
  • 50
    • 32344452280 scopus 로고    scopus 로고
    • Renewing the T cell repertoire to arrest autoimmune aggression
    • DOI 10.1016/j.it.2005.12.003, PII S1471490605002942
    • Muraro PA, Douek DC. Renewing the T-cell repertoire to arrest autoimmune aggression. Trends Immunol. 2006;27(2):61-7. doi:10.1016/j.it.2005.12.003. (Pubitemid 43221971)
    • (2006) Trends in Immunology , vol.27 , Issue.2 , pp. 61-67
    • Muraro, P.A.1    Douek, D.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.