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Volumn 29, Issue 12, 2014, Pages 2653-2665

Runx2 regulates endochondral ossification through control of chondrocyte proliferation and differentiation

Author keywords

Cartilage remodeling; Chondrocyte differentiation; RUNX2; Skeletal development

Indexed keywords

CYCLIN A1; GPR132 PROTEIN; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN C MYB; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; OSTEOPROTEGERIN; RUNX2 PROTEIN, MOUSE; SOX9 PROTEIN, MOUSE; TNFRSF11B PROTEIN, MOUSE; TNFSF11 PROTEIN, MOUSE;

EID: 84904253127     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.2287     Document Type: Article
Times cited : (123)

References (59)
  • 2
    • 26844502418 scopus 로고    scopus 로고
    • Transcriptional control of chondrocyte fate and differentiation
    • Lefebvre V, Smits P. Transcriptional control of chondrocyte fate and differentiation. Birth Defects Res C Embryo Today. 2005;75(3): 200-12.
    • (2005) Birth Defects Res C Embryo Today. , vol.75 , Issue.3 , pp. 200-212
    • Lefebvre, V.1    Smits, P.2
  • 3
    • 0034747252 scopus 로고    scopus 로고
    • BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation
    • Minina E, Wenzel HM, Kreschel C, et al. BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation. Development. 2001;128(22): 4523-34.
    • (2001) Development. , vol.128 , Issue.22 , pp. 4523-4534
    • Minina, E.1    Wenzel, H.M.2    Kreschel, C.3
  • 4
    • 33744764558 scopus 로고    scopus 로고
    • PTHrP and skeletal development
    • Kronenberg HM. PTHrP and skeletal development. Ann NY Acad Sci. 2006;1068: 1-13.
    • (2006) Ann NY Acad Sci. , vol.1068 , pp. 1-13
    • Kronenberg, H.M.1
  • 5
    • 0033567213 scopus 로고    scopus 로고
    • Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
    • St-Jacques B, Hammerschmidt M, McMahon AP. Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev. 1999;13(16): 2072-86.
    • (1999) Genes Dev. , vol.13 , Issue.16 , pp. 2072-2086
    • St-Jacques, B.1    Hammerschmidt, M.2    McMahon, A.P.3
  • 6
    • 33645082395 scopus 로고    scopus 로고
    • PTH/PTHrP receptor delays chondrocyte hypertrophy via both Runx2-dependent and -independent pathways
    • Guo J, Chung UI, Yang D, Karsenty G, Bringhurst FR, Kronenberg HM. PTH/PTHrP receptor delays chondrocyte hypertrophy via both Runx2-dependent and -independent pathways. Dev Biol. 2006; 292(1): 116-28.
    • (2006) Dev Biol. , vol.292 , Issue.1 , pp. 116-128
    • Guo, J.1    Chung, U.I.2    Yang, D.3    Karsenty, G.4    Bringhurst, F.R.5    Kronenberg, H.M.6
  • 7
    • 0029750190 scopus 로고    scopus 로고
    • Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein
    • Vortkamp A, Lee K, Lanske B, Segre GV, Kronenberg HM, Tabin CJ. Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein. Science. 1996;273(5275): 613-22.
    • (1996) Science. , vol.273 , Issue.5275 , pp. 613-622
    • Vortkamp, A.1    Lee, K.2    Lanske, B.3    Segre, G.V.4    Kronenberg, H.M.5    Tabin, C.J.6
  • 8
    • 0028057743 scopus 로고
    • Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene
    • Karaplis AC, Luz A, Glowacki J, et al. Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene. Genes Dev. 1994;8(3): 277-89.
    • (1994) Genes Dev. , vol.8 , Issue.3 , pp. 277-289
    • Karaplis, A.C.1    Luz, A.2    Glowacki, J.3
  • 9
    • 0027968182 scopus 로고
    • Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation
    • Amizuka N, Warshawsky H, Henderson JE, Goltzman D, Karaplis AC. Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation. J Cell Biol. 1994;126(6): 1611-23.
    • (1994) J Cell Biol. , vol.126 , Issue.6 , pp. 1611-1623
    • Amizuka, N.1    Warshawsky, H.2    Henderson, J.E.3    Goltzman, D.4    Karaplis, A.C.5
  • 10
    • 0033950445 scopus 로고    scopus 로고
    • Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone relatedprotein- dependent and -independent pathways
    • Karp SJ, Schipani E, St-Jacques B, Hunzelman J, Kronenberg H, McMahon AP. Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone relatedprotein- dependent and -independent pathways. Development. 2000;127(3): 543-8.
    • (2000) Development. , vol.127 , Issue.3 , pp. 543-548
    • Karp, S.J.1    Schipani, E.2    St-Jacques, B.3    Hunzelman, J.4    Kronenberg, H.5    McMahon, A.P.6
  • 11
    • 0036744820 scopus 로고    scopus 로고
    • Interaction of FGF Ihh/Pthlh and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation
    • Minina E, Kreschel C, Naski MC, Ornitz DM, Vortkamp A. Interaction of FGF, Ihh/Pthlh, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation. Dev Cell. 2002;3(3): 439-49.
    • (2002) Dev Cell. , vol.3 , Issue.3 , pp. 439-449
    • Minina, E.1    Kreschel, C.2    Naski, M.C.3    Ornitz, D.M.4    Vortkamp, A.5
  • 12
    • 0029876835 scopus 로고    scopus 로고
    • Requirement for BMP signaling in interdigital apoptosis and scale formation
    • Zou H, Niswander L. Requirement for BMP signaling in interdigital apoptosis and scale formation. Science. 1996;272(5262): 738-41.
    • (1996) Science. , vol.272 , Issue.5262 , pp. 738-741
    • Zou, H.1    Niswander, L.2
  • 13
    • 0030955344 scopus 로고    scopus 로고
    • Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage
    • Zou H, Wieser R, Massague J, Niswander L. Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage. Genes Dev. 1997;11(17): 2191-203.
    • (1997) Genes Dev. , vol.11 , Issue.17 , pp. 2191-2203
    • Zou, H.1    Wieser, R.2    Massague, J.3    Niswander, L.4
  • 14
    • 33748148734 scopus 로고    scopus 로고
    • Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis
    • Spater D, Hill TP, O'Sullivan RJ, Gruber M, Conner DA, Hartmann C. Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis. Development. 2006;133(15): 3039-49.
    • (2006) Development. , vol.133 , Issue.15 , pp. 3039-3049
    • Spater, D.1    Hill, T.P.2    O'Sullivan, R.J.3    Gruber, M.4    Conner, D.A.5    Hartmann, C.6
  • 15
    • 0036830491 scopus 로고    scopus 로고
    • The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6
    • Akiyama H, Chaboissier MC, Martin JF, Schedl A, de Crombrugghe B. The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev. 2002;16(21): 2813-28.
    • (2002) Genes Dev. , vol.16 , Issue.21 , pp. 2813-2828
    • Akiyama, H.1    Chaboissier, M.C.2    Martin, J.F.3    Schedl, A.4    De Crombrugghe, B.5
  • 16
    • 84863254029 scopus 로고    scopus 로고
    • Sox9 directs hypertrophic maturation and blocks osteoblast differentiation of growth plate chondrocytes
    • Dy P, Wang W, Bhattaram P, et al. Sox9 directs hypertrophic maturation and blocks osteoblast differentiation of growth plate chondrocytes. Dev Cell. 2012;22(3): 597-609.
    • (2012) Dev Cell. , vol.22 , Issue.3 , pp. 597-609
    • Dy, P.1    Wang, W.2    Bhattaram, P.3
  • 17
    • 0031003272 scopus 로고    scopus 로고
    • SOX9 directly regulates the type-II collagen gene
    • Bell DM, Leung KK, Wheatley SC, et al. SOX9 directly regulates the type-II collagen gene. Nat Genet. 1997;16(2): 174-8.
    • (1997) Nat Genet. , vol.16 , Issue.2 , pp. 174-178
    • Bell, D.M.1    Leung, K.K.2    Wheatley, S.C.3
  • 18
    • 0035431807 scopus 로고    scopus 로고
    • The transcription factors L-Sox5 and Sox6 are essential for cartilage formation
    • Smits P, Li P, Mandel J, et al. The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001;1(2): 277-90.
    • (2001) Dev Cell. , vol.1 , Issue.2 , pp. 277-290
    • Smits, P.1    Li, P.2    Mandel, J.3
  • 19
    • 0035902565 scopus 로고    scopus 로고
    • Subnuclear targeting of Runx/Cbfa/ AML factors is essential for tissue-specific differentiation during embryonic development
    • Choi JY, Pratap J, Javed A, et al. Subnuclear targeting of Runx/Cbfa/ AML factors is essential for tissue-specific differentiation during embryonic development. Proc Natl Acad Sci USA. 2001;98(15): 8650-5.
    • (2001) Proc Natl Acad Sci USA. , vol.98 , Issue.15 , pp. 8650-8655
    • Choi, J.Y.1    Pratap, J.2    Javed, A.3
  • 20
    • 33751106713 scopus 로고    scopus 로고
    • Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium
    • Hinoi E, Bialek P, Chen YT, et al. Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes Dev. 2006;20(21): 2937-42.
    • (2006) Genes Dev. , vol.20 , Issue.21 , pp. 2937-2942
    • Hinoi, E.1    Bialek, P.2    Chen, Y.T.3
  • 21
    • 0030684749 scopus 로고    scopus 로고
    • Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
    • Komori T, Yagi H, Nomura S, et al. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell. 1997;89(5): 755-64.
    • (1997) Cell. , vol.89 , Issue.5 , pp. 755-764
    • Komori, T.1    Yagi, H.2    Nomura, S.3
  • 22
    • 0035118709 scopus 로고    scopus 로고
    • Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice
    • Takeda S, Bonnamy JP, Owen MJ, Ducy P, Karsenty G. Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. Genes Dev. 2001;15(4): 467-81.
    • (2001) Genes Dev. , vol.15 , Issue.4 , pp. 467-481
    • Takeda, S.1    Bonnamy, J.P.2    Owen, M.J.3    Ducy, P.4    Karsenty, G.5
  • 23
    • 0035795405 scopus 로고    scopus 로고
    • Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes
    • Ueta C, Iwamoto M, Kanatani N, et al. Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes. J Cell Biol. 2001;153(1): 87-100.
    • (2001) J Cell Biol. , vol.153 , Issue.1 , pp. 87-100
    • Ueta, C.1    Iwamoto, M.2    Kanatani, N.3
  • 24
    • 0032949156 scopus 로고    scopus 로고
    • Maturational disturbance of chondrocytes in Cbfa1-deficient mice
    • Inada M, Yasui T, Nomura S, et al. Maturational disturbance of chondrocytes in Cbfa1-deficient mice. Dev Dyn. 1999;214(4): 279-90.
    • (1999) Dev Dyn. , vol.214 , Issue.4 , pp. 279-290
    • Inada, M.1    Yasui, T.2    Nomura, S.3
  • 25
    • 11144354938 scopus 로고    scopus 로고
    • Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog
    • Yoshida CA, Yamamoto H, Fujita T, et al. Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog. Genes Dev. 2004; 18(8): 952-63.
    • (2004) Genes Dev. , vol.18 , Issue.8 , pp. 952-963
    • Yoshida, C.A.1    Yamamoto, H.2    Fujita, T.3
  • 26
    • 84862537126 scopus 로고    scopus 로고
    • Targeting Runx2 expression in hypertrophic chondrocytes impairs endochondral ossification during early skeletal development
    • Ding M, Lu Y, Abbassi S, et al. Targeting Runx2 expression in hypertrophic chondrocytes impairs endochondral ossification during early skeletal development. J Cell Physiol. 2012;227(10): 3446-56.
    • (2012) J Cell Physiol. , vol.227 , Issue.10 , pp. 3446-3456
    • Ding, M.1    Lu, Y.2    Abbassi, S.3
  • 27
    • 80051789103 scopus 로고    scopus 로고
    • Chondrocyte-specific regulatory activity of Runx2 is essential for survival and skeletal development
    • Chen H, Ghori-Javed FY, Rashid H, Serra R, Gutierrez SE, Javed A. Chondrocyte-specific regulatory activity of Runx2 is essential for survival and skeletal development. Cells Tissues Organs. 2011; 194(2-4): 161-5.
    • (2011) Cells Tissues Organs. , vol.194 , Issue.2-4 , pp. 161-165
    • Chen, H.1    Ghori-Javed, F.Y.2    Rashid, H.3    Serra, R.4    Gutierrez, S.E.5    Javed, A.6
  • 28
    • 84884521604 scopus 로고    scopus 로고
    • An analysis of skeletal development in osteoblast-specific and chondrocyte-specific runtrelated transcription factor-2 (Runx2) knockout mice
    • Takarada T, Hinoi E, Nakazato R, et al. An analysis of skeletal development in osteoblast-specific and chondrocyte-specific runtrelated transcription factor-2 (Runx2) knockout mice. J Bone Miner Res. 2013;28(10): 2064-9.
    • (2013) J Bone Miner Res. , vol.28 , Issue.10 , pp. 2064-2069
    • Takarada, T.1    Hinoi, E.2    Nakazato, R.3
  • 29
    • 12944265540 scopus 로고    scopus 로고
    • Col2a1- directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice
    • Ovchinnikov DA, Deng JM, Ogunrinu G, Behringer RR. Col2a1- directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice. Genesis. 2000;26(2): 145-6.
    • (2000) Genesis. , vol.26 , Issue.2 , pp. 145-146
    • Ovchinnikov, D.A.1    Deng, J.M.2    Ogunrinu, G.3    Behringer, R.R.4
  • 30
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet. 1999;21(1): 70-1.
    • (1999) Nat Genet. , vol.21 , Issue.1 , pp. 70-71
    • Soriano, P.1
  • 31
    • 2342476573 scopus 로고    scopus 로고
    • Regulatory controls for osteoblast growth and differentiation: Role of Runx/Cbfa/AML factors
    • Lian JB, Javed A, Zaidi SK, et al. Regulatory controls for osteoblast growth and differentiation: Role of Runx/Cbfa/AML factors. Crit Rev Eukaryot Gene Expr. 2004;14(1-2): 1-41.
    • (2004) Crit Rev Eukaryot Gene Expr. , vol.14 , Issue.1-2 , pp. 1-41
    • Lian, J.B.1    Javed, A.2    Zaidi, S.K.3
  • 32
    • 43749091299 scopus 로고    scopus 로고
    • Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal
    • Javed A, Bae JS, Afzal F, et al. Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal. J Biol Chem. 2008; 283(13): 8412-22.
    • (2008) J Biol Chem. , vol.283 , Issue.13 , pp. 8412-8422
    • Javed, A.1    Bae, J.S.2    Afzal, F.3
  • 33
    • 26844574658 scopus 로고    scopus 로고
    • Runx2: A master organizer of gene transcription in developing and maturing osteoblasts
    • Schroeder TM, Jensen ED, Westendorf JJ. Runx2: A master organizer of gene transcription in developing and maturing osteoblasts. Birth Defects Res C Embryo Today. 2005;75(3): 213-25.
    • (2005) Birth Defects Res C Embryo Today. , vol.75 , Issue.3 , pp. 213-225
    • Schroeder, T.M.1    Jensen, E.D.2    Westendorf, J.J.3
  • 34
    • 0030666372 scopus 로고    scopus 로고
    • Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
    • Otto F, Thornell AP, Crompton T, et al. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell. 1997;89(5): 765-71.
    • (1997) Cell. , vol.89 , Issue.5 , pp. 765-771
    • Otto, F.1    Thornell, A.P.2    Crompton, T.3
  • 35
    • 84875588737 scopus 로고    scopus 로고
    • The transcriptional co-regulator Jab1 is crucial for chondrocyte differentiation in vivo
    • Chen D, Bashur LA, Liang B, et al. The transcriptional co-regulator Jab1 is crucial for chondrocyte differentiation in vivo. J Cell Sci. 2013;126(Pt 1): 234-43.
    • (2013) J Cell Sci. , vol.126 , pp. 234-243
    • Chen, D.1    Bashur, L.A.2    Liang, B.3
  • 36
    • 84856795723 scopus 로고    scopus 로고
    • BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development
    • Shu B, Zhang M, Xie R, et al. BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development. J Cell Sci. 2011;124(Pt 20): 3428-40.
    • (2011) J Cell Sci. , vol.124 , pp. 3428-3440
    • Shu, B.1    Zhang, M.2    Xie, R.3
  • 37
    • 15544381189 scopus 로고    scopus 로고
    • Runx2 regulates endochondral ossification in condyle during mandibular advancement
    • Tang GH, Rabie AB. Runx2 regulates endochondral ossification in condyle during mandibular advancement. J Dent Res. 2005;84(2): 166-71.
    • (2005) J Dent Res. , vol.84 , Issue.2 , pp. 166-171
    • Tang, G.H.1    Rabie, A.B.2
  • 38
    • 0141705433 scopus 로고    scopus 로고
    • Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts
    • Pratap J, Galindo M, Zaidi SK, et al. Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts. Cancer Res. 2003;63(17): 5357-2.
    • (2003) Cancer Res. , vol.63 , Issue.17 , pp. 5357-5352
    • Pratap, J.1    Galindo, M.2    Zaidi, S.K.3
  • 39
    • 0345059753 scopus 로고    scopus 로고
    • The 14-3-3 cancer connection
    • Hermeking H. The 14-3-3 cancer connection. Nat Rev Cancer. 2003;3(12): 931-43.
    • (2003) Nat Rev Cancer. , vol.3 , Issue.12 , pp. 931-943
    • Hermeking, H.1
  • 40
    • 0033533612 scopus 로고    scopus 로고
    • 14-3- 3Sigma is required to prevent mitotic catastrophe after DNA damage
    • Chan TA, Hermeking H, Lengauer C, Kinzler KW, Vogelstein B. 14-3- 3Sigma is required to prevent mitotic catastrophe after DNA damage. Nature. 1999;401(6753): 616-20.
    • (1999) Nature. , vol.401 , Issue.6753 , pp. 616-620
    • Chan, T.A.1    Hermeking, H.2    Lengauer, C.3    Kinzler, K.W.4    Vogelstein, B.5
  • 41
    • 0034725698 scopus 로고    scopus 로고
    • Association of the cyclindependent kinases and 14-3-3 sigma negatively regulates cell cycle progression
    • Laronga C, Yang HY, Neal C, Lee MH. Association of the cyclindependent kinases and 14-3-3 sigma negatively regulates cell cycle progression. J Biol Chem. 2000;275(30): 23106-12.
    • (2000) J Biol Chem. , vol.275 , Issue.30 , pp. 23106-2312
    • Laronga, C.1    Yang, H.Y.2    Neal, C.3    Lee, M.H.4
  • 42
    • 27644529779 scopus 로고    scopus 로고
    • A mutation in stratifin is responsible for the repeated epilation (Er) phenotype in mice
    • Herron BJ, Liddell RA, Parker A, et al. A mutation in stratifin is responsible for the repeated epilation (Er) phenotype in mice. Nat Genet. 2005;37(11): 1210-2.
    • (2005) Nat Genet. , vol.37 , Issue.11 , pp. 1210-1212
    • Herron, B.J.1    Liddell, R.A.2    Parker, A.3
  • 43
    • 84863531140 scopus 로고    scopus 로고
    • Subcellular relocation of histone deacetylase 4 regulates growth plate chondrocyte differentiation through Ca2+/calmodulin-dependent kinase IV
    • Guan Y, Chen Q, Yang X, et al. Subcellular relocation of histone deacetylase 4 regulates growth plate chondrocyte differentiation through Ca2+/calmodulin-dependent kinase IV. Am J Physiol Cell Physiol. 2012;303(1): C33-40.
    • (2012) Am J Physiol Cell Physiol. , vol.303 , Issue.1 , pp. C33-40
    • Guan, Y.1    Chen, Q.2    Yang, X.3
  • 44
    • 8344261349 scopus 로고    scopus 로고
    • Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis
    • Vega RB, Matsuda K, Oh J, et al. Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis. Cell. 2004;119(4): 555-66.
    • (2004) Cell. , vol.119 , Issue.4 , pp. 555-566
    • Vega, R.B.1    Matsuda, K.2    Oh, J.3
  • 45
    • 0032514679 scopus 로고    scopus 로고
    • A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M
    • Weng Z, Fluckiger AC, Nisitani S, et al. A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M. Proc Natl Acad Sci USA. 1998;95(21): 12334-9.
    • (1998) Proc Natl Acad Sci USA. , vol.95 , Issue.21 , pp. 12334-1239
    • Weng, Z.1    Fluckiger, A.C.2    Nisitani, S.3
  • 46
    • 79952047942 scopus 로고    scopus 로고
    • Dramatic repositioning of c-Myb to different promoters during the cell cycle observed by combining cell sorting with chromatin immunoprecipitation
    • Quintana AM, Zhou YE, Pena JJ, O'Rourke JP, Ness SA. Dramatic repositioning of c-Myb to different promoters during the cell cycle observed by combining cell sorting with chromatin immunoprecipitation. PLoS One. 2011;6(2): E17362.
    • (2011) PLoS One. , vol.6 , Issue.2 , pp. e17362
    • Quintana, A.M.1    Zhou, Y.E.2    Pena, J.J.3    O'Rourke, J.P.4    Ness, S.A.5
  • 47
    • 33947219492 scopus 로고    scopus 로고
    • C-Myb contributes to G2/M cell cycle transition in human hematopoietic cells by direct regulation of cyclin B1 expression
    • Nakata Y, Shetzline S, Sakashita C, et al. c-Myb contributes to G2/M cell cycle transition in human hematopoietic cells by direct regulation of cyclin B1 expression. Mol Cell Biol. 2007;27(6): 2048-58.
    • (2007) Mol Cell Biol. , vol.27 , Issue.6 , pp. 2048-2058
    • Nakata, Y.1    Shetzline, S.2    Sakashita, C.3
  • 48
    • 0025821494 scopus 로고    scopus 로고
    • A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis
    • Mucenski ML, McLain K, Kier AB, et al. A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell. 2001;65(4): 677-89.
    • (2001) Cell. , vol.65 , Issue.4 , pp. 677-689
    • Mucenski, M.L.1    McLain, K.2    Kier, A.B.3
  • 49
    • 0027494125 scopus 로고
    • Reversal of terminal differentiation and control of DNA replication: Cyclin A and Cdk2 specifically localize at subnuclear sites of DNA replication
    • Cardoso MC, Leonhardt H, Nadal-Ginard B. Reversal of terminal differentiation and control of DNA replication: Cyclin A and Cdk2 specifically localize at subnuclear sites of DNA replication. Cell. 1993;74(6): 979-92.
    • (1993) Cell. , vol.74 , Issue.6 , pp. 979-992
    • Cardoso, M.C.1    Leonhardt, H.2    Nadal-Ginard, B.3
  • 51
    • 0031030730 scopus 로고    scopus 로고
    • Delayed early embryonic lethality following disruption of the murine cyclin A2 gene
    • Murphy M, Stinnakre MG, Senamaud-Beaufort C, et al. Delayed early embryonic lethality following disruption of the murine cyclin A2 gene. Nat Genet. 1997;15(1): 83-6.
    • (1997) Nat Genet. , vol.15 , Issue.1 , pp. 83-86
    • Murphy, M.1    Stinnakre, M.G.2    Senamaud-Beaufort, C.3
  • 52
    • 84870414356 scopus 로고    scopus 로고
    • Cyclin A1 is essential for setting the pluripotent state and reducing tumorigenicity of induced pluripotent stem cells
    • McLenachan S, Menchon C, Raya A, Consiglio A, Edel MJ. Cyclin A1 is essential for setting the pluripotent state and reducing tumorigenicity of induced pluripotent stem cells. Stem Cells Dev. 2012;21(15): 2891-9.
    • (2012) Stem Cells Dev. , vol.21 , Issue.15 , pp. 2891-2899
    • McLenachan, S.1    Menchon, C.2    Raya, A.3    Consiglio, A.4    Edel, M.J.5
  • 53
    • 13444256205 scopus 로고    scopus 로고
    • Molecular mechanisms of endochondral bone development
    • Provot S, Schipani E. Molecular mechanisms of endochondral bone development. Biochem Biophys Res Commun. 2005;328(3): 658-65.
    • (2005) Biochem Biophys Res Commun. , vol.328 , Issue.3 , pp. 658-665
    • Provot, S.1    Schipani, E.2
  • 54
    • 0035793055 scopus 로고    scopus 로고
    • The chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bones
    • Huang W, Chung UI, Kronenberg HM, de Crombrugghe B. The chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bones. Proc Natl Acad Sci USA. 2001;98(1): 160-5.
    • (2001) Proc Natl Acad Sci USA. , vol.98 , Issue.1 , pp. 160-165
    • Huang, W.1    Chung, U.I.2    Kronenberg, H.M.3    De Crombrugghe, B.4
  • 55
    • 34447500094 scopus 로고    scopus 로고
    • Dominance of SOX9 function over RUNX2 during skeletogenesis
    • Zhou G, Zheng Q, Engin F, et al. Dominance of SOX9 function over RUNX2 during skeletogenesis. Proc Natl Acad Sci USA. 2006;103(50): 19004-9.
    • (2006) Proc Natl Acad Sci USA. , vol.103 , Issue.50 , pp. 19004-19009
    • Zhou, G.1    Zheng, Q.2    Engin, F.3
  • 56
    • 77950537989 scopus 로고    scopus 로고
    • Control of RANKL gene expression
    • O'Brien CA. Control of RANKL gene expression. Bone. 2010;46(4): 911-9.
    • (2010) Bone. , vol.46 , Issue.4 , pp. 911-919
    • O'Brien, C.A.1
  • 57
    • 0033568341 scopus 로고    scopus 로고
    • RANK is essential for osteoclast and lymph node development
    • Dougall WC, Glaccum M, Charrier K, et al. RANK is essential for osteoclast and lymph node development. Genes Dev. 1999;13(18): 2412-24.
    • (1999) Genes Dev. , vol.13 , Issue.18 , pp. 2412-2424
    • Dougall, W.C.1    Glaccum, M.2    Charrier, K.3
  • 59
    • 39749130982 scopus 로고    scopus 로고
    • Murine and chicken chondrocytes regulate osteoclastogenesis by producing RANKL in response to BMP2
    • Usui M, Xing L, Drissi H, et al. Murine and chicken chondrocytes regulate osteoclastogenesis by producing RANKL in response to BMP2. J Bone Miner Res. 2008;23(3): 314-25.
    • (2008) J Bone Miner Res. , vol.23 , Issue.3 , pp. 314-325
    • Usui, M.1    Xing, L.2    Drissi, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.