Human NKG2E is expressed and forms an intracytoplasmic complex with CD94 and DAP12

Journal of Immunology

Volumn 193, Issue 2, 2014, Pages 610-616

  Orbelyan, Gerasim A ^a   Tang, Fangming ^a   Sally, Benjamin ^a   Solus, Jason ^a   Meresse, Bertrand ^a,e,f   Ciszewski, Cezary ^a   Grenier, Jean Christophe ^b,c   Barreiro, Luis B ^b,c   Lanier, Lewis L ^d   Jabri, Bana ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF MONTREAL   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e INSERM   (France)

^f UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD94 ANTIGEN; KILLER CELL ACTIVATING RECEPTOR ASSOCIATED PROTEIN; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2E; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CELL SURFACE; COMPLEX FORMATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; HYDROPHOBICITY; IMMUNOBLOTTING; INTRACELLULAR SIGNALING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; BINDING SITES; BLOTTING, WESTERN; CELL LINE; CYTOPLASM; ENDOPLASMIC RETICULUM; HEK293 CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; MUTATION; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY C; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY D; PHYLOGENY; PROTEIN BINDING; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84904250330     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400556     Document Type: Article

References (32)

1. Tassi, I., J. Klesney-Tait, and M. Colonna. 2006. Dissecting natural killer cell activation pathways through analysis of genetic mutations in human and mouse. Immunol. Rev. 214: 92-105. (Pubitemid 44707904)
2. Lanier, L. L. 2008. Up on the tightrope: natural killer cell activation and inhibition. Nat. Immunol. 9: 495-502. (Pubitemid 351560518)
3. Meresse, B., and B. Jabri. 2006. NKG2 receptor-mediated regulation of effector CTL functions in the human tissue microenvironment. Curr. Top. Microbiol. Immunol. 298: 139-156. (Pubitemid 41491726)
4. Raulet, D. H. 2004. Interplay of natural killer cells and their receptors with the adaptive immune response. Nat. Immunol. 5: 996-1002. (Pubitemid 41057716)
5. + T cells. Nat. Rev. Immunol. 11: 645-657.
6. Scalzo, A. A., and W. M. Yokoyama. 2008. Cmv1 and natural killer cell responses to murine cytomegalovirus infection. Curr. Top. Microbiol. Immunol. 321: 101-122.
7. Schleinitz, N., F. Vély, J. R. Harlé, and E. Vivier. 2010. Natural killer cells in human autoimmune diseases. Immunology 131: 451-458.
8. López-Botet, M., T. Bellón, M. Llano, F. Navarro, P. García, and M. de Miguel. 2000. Paired inhibitory and triggering NK cell receptors for HLA class I molecules. Hum. Immunol. 61: 7-17. (Pubitemid 30058762)
9. Steinle, A., P. Li, D. L. Morris, V. Groh, L. L. Lanier, R. K. Strong, and T. Spies. 2001. Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family. Immunogenetics 53: 279-287. (Pubitemid 32678762)
10. Kim, D. K., J. Kabat, F. Borrego, T. B. Sanni, C. H. You, and J. E. Coligan. 2004. Human NKG2F is expressed and can associate with DAP12. Mol. Immunol. 41: 53-62. (Pubitemid 38609396)
11. Braud, V. M., D. S. Allan, C. A. O'Callaghan, K. Söderström, A. D'Andrea, G. S. Ogg, S. Lazetic, N. T. Young, J. I. Bell, J. H. Phillips, et al. 1998. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 391: 795-799. (Pubitemid 28099678)
12. Lee, N., M. Llano, M. Carretero, A. Ishitani, F. Navarro, M. López-Botet, and D. E. Geraghty. 1998. HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A. Proc. Natl. Acad. Sci. USA 95: 5199-5204. (Pubitemid 28208575)
13. Tomasello, E., and E. Vivier. 2005. KARAP/DAP12/TYROBP: three names and a multiplicity of biological functions. Eur. J. Immunol. 35: 1670-1677. (Pubitemid 40862314)
14. Lanier, L. L., B. Corliss, J. Wu, and J. H. Phillips. 1998. Association of DAP12 with activating CD94/NKG2C NK cell receptors. Immunity 8: 693-701. (Pubitemid 28294516)
15. Le Dréan, E., F. Vély, L. Olcese, A. Cambiaggi, S. Guia, G. Krystal, N. Gervois, A. Moretta, F. Jotereau, and E. Vivier. 1998. Inhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases. Eur. J. Immunol. 28: 264-276. (Pubitemid 28048297)
16. López-Botet, M., M. Llano, F. Navarro, and T. Bellón. 2000. NK cell recognition of non-classical HLA class I molecules. Semin. Immunol. 12: 109-119. (Pubitemid 30199275)
17. Meresse, B., S. A. Curran, C. Ciszewski, G. Orbelyan, M. Setty, G. Bhagat, L. Lee, M. Tretiakova, C. Semrad, E. Kistner, et al. 2006. Reprogramming of CTLs into natural killer-like cells in celiac disease. J. Exp. Med. 203: 1343-1355. (Pubitemid 43736602)
18. Park, K. S., J. H. Park, and Y. W. Song. 2008. Inhibitory NKG2A and activating NKG2D and NKG2C natural killer cell receptor genes: susceptibility for rheumatoid arthritis. Tissue Antigens 72: 342-346.
19. Gumá, M., A. Angulo, C. Vilches, N. Gómez-Lozano, N. Malats, and M. López-Botet. 2004. Imprint of human cytomegalovirus infection on the NK cell receptor repertoire. Blood 104: 3664-3671. (Pubitemid 39564443)
20. Call, M. E., K. W. Wucherpfennig, and J. J. Chou. 2010. The structural basis for intramembrane assembly of an activating immunoreceptor complex. Nat. Immunol. 11: 1023-1029.
21. Kaiser, B. K., F. Barahmand-Pour, W. Paulsene, S. Medley, D. E. Geraghty, and R. K. Strong. 2005. Interactions between NKG2x immunoreceptors and HLA-E ligands display overlapping affinities and thermodynamics. J. Immunol. 174: 2878-2884. (Pubitemid 40279705)
22. Vance, R. E., A. M. Jamieson, and D. H. Raulet. 1999. Recognition of the class Ib molecule Qa-1b by putative activating receptors CD94/NKG2C and CD94/NKG2E on mouse natural killer cells. J. Exp. Med. 190: 1801-1812. (Pubitemid 30013846)
23. Fang, M., M. T. Orr, P. Spee, T. Egebjerg, L. L. Lanier, and L. J. Sigal. 2011. CD94 is essential for NK cell-mediated resistance to a lethal viral disease. Immunity 34: 579-589.
24. Jabri, B., J. M. Selby, H. Negulescu, L. Lee, A. I. Roberts, A. Beavis, M. Lopez-Botet, E. C. Ebert, and R. J. Winchester. 2002. TCR specificity dictates CD94/NKG2A expression by human CTL. Immunity 17: 487-499. (Pubitemid 35223537)
25. Stamatakis, A. 2006. RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models. Bioinformatics 22: 2688-2690. (Pubitemid 44642609)
26. Edgar, R. C. 2004. MUSCLE: a multiple sequence alignment method with reduced time and space complexity. BMC Bioinformatics 5: 113.
27. Larkin, M. A., G. Blackshields, N. P. Brown, R. Chenna, P. A. McGettigan, H. McWilliam, F. Valentin, I. M. Wallace, A. Wilm, R. Lopez, et al. 2007. Clustal W and Clustal X version 2.0. Bioinformatics 23: 2947-2948. (Pubitemid 350162903)
28. Li, W. H., C. I. Wu, and C. C. Luo. 1985. A new method for estimating synonymous and nonsynonymous rates of nucleotide substitution considering the relative likelihood of nucleotide and codon changes. Mol. Biol. Evol. 2: 150-174. (Pubitemid 15239737)
29. Schröder, M., and R. J. Kaufman. 2005. The mammalian unfolded protein response. Annu. Rev. Biochem. 74: 739-789. (Pubitemid 40995523)
30. Vitale, M., C. Bottino, S. Sivori, L. Sanseverino, R. Castriconi, E. Marcenaro, R. Augugliaro, L. Moretta, and A. Moretta. 1998. NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis. J. Exp. Med. 187: 2065-2072. (Pubitemid 28285576)
31. Lanier, L. L., B. C. Corliss, J. Wu, C. Leong, and J. H. Phillips. 1998. Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells. Nature 391: 703-707. (Pubitemid 28113218)
32. Rajagopalan, S., Y. T. Bryceson, S. P. Kuppusamy, D. E. Geraghty, A. van der Meer, I. Joosten, and E. O. Long. 2006. Activation of NK cells by an endocytosed receptor for soluble HLA-G. PLoS Biol. 4: e9.