System vaccinology for the evaluation of influenza vaccine safety by multiplex gene detection of novel biomarkers in a preclinical study and batch release test

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Mizukami, Takuo ^a   Momose, Haruka ^a   Kuramitsu, Madoka ^a   Takizawa, Kazuya ^a   Araki, Kumiko ^a   Furuhata, Keiko ^a   Ishii, Ken J ^b,c   Hamaguchi, Isao ^a   Yamaguchi, Kazunari ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; INFLUENZA VACCINE; TRIPLE VACCINE; TRANSCRIPTOME;

ACCURACY; ANALYTIC METHOD; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BATCH RELEASE TEST; BETA 2M GENE; BODY WEIGHT; C2 GENE; CLINICAL EVALUATION; CONTROLLED STUDY; CSF1 GENE; CXCL11 GENE; CXCL9 GENE; DRUG MANUFACTURE; DRUG SAFETY; DRUG SCREENING; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC SCREENING; IFI47 GENE; IFRD1 GENE; INFLUENZA A (H5N1); INTERMETHOD COMPARISON; IRF7 GENE; LGALS9 GENE; LGALSBP3 GENE; MALE; MARKER GENE; MX2 GENE; NGFR GENE; NONHUMAN; NPC1 GENE; PANDEMIC INFLUENZA; PREDICTION; PSMB9 GENE; PSME1 GENE; RAT; TAP2 GENE; TAPBP GENE; TIMP1 GENE; TOXICITY TESTING; TRAFD1 GENE; VACCINE PRODUCTION; ZBP1 GENE; ANIMAL; IMMUNOLOGY; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H3N2; INFLUENZA VIRUS A H5N1; METABOLISM; PROCEDURES; SAFETY; SEASON;

ANIMALS; BIOLOGICAL MARKERS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA VACCINES; MALE; RATS; SAFETY; SEASONS; TOXICITY TESTS; TRANSCRIPTOME;

EID: 84904248196     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0101835     Document Type: Article

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