The Friend leukaemia virus integration 1 (Fli-1) transcription factor affects lupus nephritis development by regulating inflammatory cell infiltration into the kidney

Clinical and Experimental Immunology

Volumn 177, Issue 1, 2014, Pages 102-109

  Sato, S ^a   Zhang, X K ^a  

^a RALPH H JOHNSON VA MEDICAL CENTER   (United States)

Author keywords

Chemokines; Chemotaxis; Fli 1; Infiltration; Lupus nephritis

Indexed keywords

DOUBLE STRANDED DNA ANTIBODY; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TRANSCRIPTION FACTOR FLI 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; CELL COUNT; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; DISEASE ASSOCIATION; IMMUNOPATHOGENESIS; IMMUNOREGULATION; IN VITRO STUDY; INFLAMMATORY CELL; INFLAMMATORY INFILTRATE; KIDNEY; LUPUS ERYTHEMATOSUS NEPHRITIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

CHEMOKINES; CHEMOTAXIS; FLI-1; INFILTRATION; LUPUS NEPHRITIS;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; CHEMOKINES; CHEMOTAXIS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOTHERAPY; INFLAMMATION; KIDNEY; LUPUS NEPHRITIS; MICE; MICE, INBRED MRL LPR; MICE, TRANSGENIC; PROTO-ONCOGENE PROTEIN C-FLI-1;

EID: 84904240438     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12310     Document Type: Article

References (38)

1. D'Cruz DP, Khamashta MA, Hughes GR. Systemic lupus erythematosus. Lancet 2007; 369:587-596.
2. Borchers AT, Leibushor N, Naguwa SM, Cheema GS, Shoenfeld Y, Gershwin ME. Lupus nephritis: a critical review. Autoimmun Rev 2012; 12:174-194.
3. Cameron JS. Lupus nephritis. J Am Soc Nephrol 1999; 10:413-424.
4. Boucher A, Droz D, Adafer E, Noël LH. Characterization of mononuclear cell subsets in renal cellular interstitial infiltrates. Kidney Int 1986; 29:1043-1049.
5. Alexopoulos E, Seron D, Hartley RB, Cameron JS. Lupus nephritis: correlation of interstitial cells with glomerular function. Kidney Int 1990; 37:100-109.
6. de Zubiria Salgado A, Herrera-Diaz C. Lupus nephritis: an overview of recent findings. Autoimmune Dis 2012; 2012:Article ID 849684, 21 pp.
7. Castiglione A, Bucci A, Fellin G, d'Amico G, Atkins RC. The relationship of infiltrating renal leucocytes to disease activity in lupus and cryoglobulinaemic glomerulonephritis. Nephron 1988; 50:14-23.
8. Nowling TK, Gilkeson GS. Mechanisms of tissue injury in lupus nephritis. Arthritis Res Ther 2011; 13:250-259.
9. Zoja C, Liu XH, Donadelli R etal. Renal expression of monocyte chemoattractant protein-1 in lupus autoimmune mice. J Am Soc Nephrol 1997; 8:720-729.
10. Moore KJ, Wada T, Barbee SD, Kelley VR. Gene transfer of RANTES elicits autoimmune renal injury in MRL-Fas(1pr) mice. Kidney Int 1998; 53:1631-1641.
11. Pérez de Lema G, Maier H, Nieto E etal. Chemokine expression precedes inflammatory cell infiltration and chemokine receptor and cytokine expression during the initiation of murine lupus nephritis. J Am Soc Nephrol 2001; 12:1369-1382.
12. Tesch GH, Maifert S, Schwarting A, Rollins BJ, Kelley VR. Monocyte chemoattractant protein 1-dependent leukocytic infiltrates are responsible for autoimmune disease in MRL-Fas(lpr) mice. J Exp Med 1999; 190:1813-1824.
13. Ben-David Y, Giddens EB, Letwin K etal. Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1. Genes Rev 1991; 5:908-918.
14. Watson DK, Smyth FE, Thompson DM etal. The ERGB/Fli-1 gene: isolation and characterization of a new member of the family of human ETS transcription factors. Cell Growth Differ 1992; 3:705-713.
15. Seth A, Ascione R, Fisher RJ, Mavrothalassitis GJ, Bhat NK, Papas TS. The ets gene family. Cell Growth Differ 1992; 3:327-334.
16. Karim FD, Urness LD, Thummel CS etal. The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequence. Genes Dev 1990; 4:1451-1453.
17. Hsu T, Trojanowska M, Watson DK. Ets proteins in biological control and cancer. J Cell Biochem 2004; 91:896-903.
18. Papas TS, Bhat NK, Spyropoulos DD etal. Functional relationships among ETS gene family members. Leukemia 1997; 11 (Suppl 3):557-566.
19. Pusztaszeri MP, Seelentag W, Bosman FT. Immunohistochemical expression of endothelial markers CD31, CD34, von Willebrand factor, and Fli-1 in normal human tissues. J Histochem Cytochem 2006; 54:385-395.
20. Spyropoulos DD, Pharr PN, Lavenburg KR etal. Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor. Mol Cell Biol 2000; 20:5643-5652.
21. Georgiou P, Maroulakou IG, Green JE etal. Expression of ets family of genes in systemic lupus erythematosus and Sjogren's syndrome. Int J Oncol 1996; 9:9-18.
22. Zhang L, Eddy A, Teng TT etal. An immunological renal disease in transgenic mice that overexpress Fli-1, a member of the ets family of transcription factor genes. Mol Cell Biol 1995; 15:6961-6970.
23. Zhang XK, Gallant S, Molano I etal. Decreased expression of the ets family transcription factor Fli-1 markedly prolongs survival and significantly reduces renal disease in MRL/lpr mice. J Immunol 2004; 173:6481-6489.
24. Mathenia J, Reyes-Cortes E, Williams S etal. Impact of Fli-1 transcription factor on autoantibody and lupus nephritis in NZM2410 mice. Clin Exp Immunol 2012; 362:362-371.
25. Suzuki E, Karam E, Williams S, Watson DK, Gilkeson G, Zhang XK. Fli-1 transcription factor affects glomerulonephritis development by regulating expression of monocyte chemoattractant protein-1 in endothelial cells in the kidney. Clin Immunol 2012; 145:201-208.
26. Okabe M, Ikawa M, Kominami K, Nakanishi T, Nishimune Y. 'Green mice' as a source of ubiquitous green cells. FEBS Lett 1997; 407:313-319.
27. Adalid-Peralta L, Mathian A, Tran T etal. Leukocytes and the kidney contribute to interstitial inflammation in lupus nephritis. Kidney Int 2008; 73:172-180.
28. Schall TJ, Bacon K, Toy KJ, Goeddel DV. Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. Nature 1990; 347:669-671.
29. Fu Q, Chen X, Cui H etal. Association of elevated transcript levels of interferon-inducible chemokines with disease activity and organ damage in systemic lupus erythematosus patients. Arthritis Res Ther 2008; 10:R112.
30. Wada T, Furuichi K, Segawa-Takaeda C etal. MIP-1alpha and MCP-1 contribute to crescents and interstitial lesions in human crescentic glomerulonephritis. Kidney Int 1999; 56:995-1003.
31. Liu ZH, Chen SF, Zhou H, Chen HP, Li LS. Glomerular expression of C-C chemokines in different types of human crescentic glomerulonephritis. Nephrol Dial Transplant 2003; 18:1526-1534.
32. Svenson JL, EuDaly J, Ruiz P, Korach KS, Gilkeson GS. Impact of estrogen receptor deficiency on disease expression in the NZM2410 lupus prone mouse. Clin Immunol 2008; 128:259-268.
33. Gladman DD, Urowitz MB, Keystone EC. Serologically active clinically quiescent systemic lupus erythematosus: a discordance between clinical and serologic features. Am J Med 1979; 66:210-215.
34. Arbuckle MR, McClain MT, Rubertone MV etal. Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 2003; 349:1526-1533.
35. Pérez de Lema G, Maier H, Franz TJ etal. Chemokine receptor Ccr2 deficiency reduces renal disease and prolongs survival in MRL/lpr lupus-prone mice. J Am Soc Nephrol 2005; 16:3592-3601.
36. Turner JE, Paust HJ, Bennstein SB etal. Protective role for CCR5 in murine lupus nephritis. Am J Physiol Renal Physiol 2012; 302:F1503-1515.
37. Richard EM, Thiyagarajan T, Bunni MA etal. Reducing FLI1 levels in the MRL/lpr lupus mouse model impacts T cell function by modulating glycosphingolipid metabolism. PLOS ONE 2013; 8:e75175. doi:10.1371/journal.pone.0075175.
38. Miyagi T, Yamaguchi K. Mammalian sialidases: physiological and pathological roles in cellular functions. Glycobiology 2012; 22:880-896.