Apigenin inhibits enterovirus 71 replication through suppressing viral IRES activity and modulating cellular JNK pathway

Antiviral Research

Volumn 109, Issue 1, 2014, Pages 30-41

  Lv, Xiaowen ^a,b   Qiu, Min ^a   Chen, Deyan ^a   Zheng, Nan ^a   Jin, Yu ^a,b   Wu, Zhiwei ^a  

^a NANJING UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Antiviral activity; Apigenin; c Jun N terminal kinase (JNK); Enterovirus 71 (EV71); Internal ribosome entry site (IRES)

Indexed keywords

APIGENIN; CYTOKINE; FLAVONE DERIVATIVE; HYDROXYL GROUP; LUTEOLIN; POLYPROTEIN; PROTEINASE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; ANTIVIRUS AGENT; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4;

ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; CYTOPATHOGENIC EFFECT; CYTOTOXICITY ASSAY; ENTEROVIRUS 71; ENZYME ACTIVATION; ENZYME INHIBITION; INTERNAL RIBOSOME ENTRY SITE; NONHUMAN; PRIORITY JOURNAL; UPREGULATION; VIRUS ENTRY; VIRUS INHIBITION; VIRUS REPLICATION; CELL LINE; DRUG EFFECTS; ENTEROVIRUS; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HAND, FOOT AND MOUTH DISEASE; HUMAN; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; VIROLOGY;

ANTIVIRAL AGENTS; APIGENIN; CELL LINE; ENTEROVIRUS A, HUMAN; GENE EXPRESSION REGULATION, VIRAL; HAND, FOOT AND MOUTH DISEASE; HUMANS; LUTEOLIN; MAP KINASE KINASE 4; SIGNAL TRANSDUCTION; VIRUS REPLICATION;

EID: 84904182933     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2014.06.004     Document Type: Article

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