Degradation of the deubiquitinating enzyme USP33 is mediated by p97 and the ubiquitin ligase HERC2

Journal of Biological Chemistry

Volumn 289, Issue 28, 2014, Pages 19789-19798

  Chan, Nickie C ^a,b   Den Besten, Willem ^a   Sweredoski, Michael J ^a,c   Hess, Sonja ^a,c   Deshaies, Raymond J ^a,b   Chan, David C ^a,b  

^a California Institute of Technology   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MASS SPECTROMETRY;

ADRENERGIC RECEPTORS; CENTROSOME AMPLIFICATION; CHEMICAL INHIBITION; DEUBIQUITINATING ENZYMES; INTRACELLULAR LEVELS; POLYUBIQUITINATION; QUANTITATIVE MASS SPECTROMETRIES; UBIQUITIN-PROTEASOME SYSTEM;

ENZYME ACTIVITY;

ADAPTOR PROTEIN; DEUBIQUITINASE; HERC2 PROTEIN; PROTEIN P97; UBIQUITIN PROTEIN LIGASE; UFD1 NPL4 PROTEIN; UNCLASSIFIED DRUG; USP33 ENZYME;

ARTICLE; BIOCHEMISTRY; CELL LEVEL; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UBIQUITINATION;

DEUBIQUITINATION; E3 UBIQUITIN LIGASE; HERC2; P97; PROTEASOME; PROTEIN DEGRADATION; UBIQUITINATION; USP33;

ADENOSINE TRIPHOSPHATASES; ANIMALS; CELL CYCLE PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HELA CELLS; HUMANS; MICE; NIH 3T3 CELLS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; UBIQUITIN; UBIQUITIN THIOLESTERASE; UBIQUITINATION;

EID: 84904175017     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.569392     Document Type: Article

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