Lack of insight 3 years after first-episode psychosis: An unchangeable illness trait determined from first presentation?

Schizophrenia Research

Volumn 157, Issue 1-3, 2014, Pages 271-277

  Ayesa Arriola, Rosa ^a,b,c   Moríñigo, Javier David López ^c   David, Anthony S ^c   Pérez Iglesias, Rocío ^a,b,c   Rodríguez Sánchez, Jose Manuel ^a,b   Crespo Facorro, Benedicto ^a,b  

^a HOSPITAL UNIVERSITARIO MARQUÉS DE VALDECILLA   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE SALUD MENTAL CIBERSAM   (Spain)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Depression; First episode psychosis; Long term insight; Multidimensional insight; Premorbid adjustment; Schizophrenia

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; COGNITION; COPING BEHAVIOR; DEPRESSION; EMPLOYMENT STATUS; EXECUTIVE FUNCTION; FEMALE; FOLLOW UP; HUMAN; INTROSPECTION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PSYCHOLOGICAL RATING SCALE; PSYCHOSIS; SCALE TO ASSESS UNAWARENESS OF MENTAL DISORDER; SCHIZOPHRENIA; AWARENESS; COHORT ANALYSIS; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; PATIENT ATTITUDE; PSYCHOLOGY; PSYCHOTIC DISORDERS; SOCIAL ADAPTATION; SPAIN; TIME; YOUNG ADULT;

ADOLESCENT; ADULT; AWARENESS; COHORT STUDIES; DEPRESSION; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PATIENT ACCEPTANCE OF HEALTH CARE; PSYCHIATRIC STATUS RATING SCALES; PSYCHOTIC DISORDERS; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SOCIAL ADJUSTMENT; SPAIN; TIME FACTORS; YOUNG ADULT;

EID: 84904112195     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2014.05.011     Document Type: Article

References (53)

1. Addington D., Addington J., Maticka-Tyndale E., Joyce J. Reliability and validity of a depression rating scale for schizophrenics. Schizophr. Res. 1992, 6(3):201-208.
2. Amador X.F., Gorman J.M. Psychopathologic domains and insight in schizophrenia. Psychiatr. Clin. N. Am. 1998, 21(1):27-42.
3. Amador X.F., Strauss D.H., Yale S.A., Flaum M.M., Endicott J., Gorman J.M. Assessment of insight in psychosis. Am. J. Psychiatry 1993, 150(6):873-879.
4. Amador X.F., Flaum M., Andreasen N.C., Strauss D.H., Yale S.A., Clark S.C., Gorman J.M. Awareness of illness in schizophrenia and schizoaffective and mood disorders. Arch. Gen. Psychiatry 1994, 51(10):826-836.
5. Andreasen N.C. Scale for the Assessment of Negative Symptoms (SANS) 1983, University of Iowa, Iowa City.
6. Andreasen N.C. Scale for the Assessment of Positive Symptoms (SAPS) 1984, University of Iowa, Iowa City.
7. Arango C., Amador X. Lessons learned about poor insight. Schizophr. Bull. 2011, 37(1):27-28.
8. Ayesa-Arriola R., Rodriguez-Sanchez J.M., Morelli C., Pelayo-Teran J.M., Perez-Iglesias R., Mata I., Martinez-Garcia O., Pardo-Garcia G., Vazquez-Barquero J.L., Crespo-Facorro B. Insight dimensions in first-episode psychosis patients: clinical, cognitive, pre-morbid and socio-demographic correlates. Early Interv. Psychiatry 2011, 5(2):140-149.
9. Boyer L., Aghababian V., Richieri R., Loundou A., Padovani R., Simeoni M.C., Auquier P., Lancon C. Insight into illness, neurocognition and quality of life in schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 2012, 36(2):271-276.
10. Boyer L., Cermolacce M., Dassa D., Fernandez J., Boucekine M., Richieri R., Vaillant F., Dumas R., Auquier P., Lancon C. Neurocognition, insight and medication nonadherence in schizophrenia: a structural equation modeling approach. PLoS ONE 2012, 7(10):e47655.
11. Campos M.S., Garcia-Jalon E., Gilleen J.K., David A.S., Peralta V.M., Cuesta M.J. Premorbid personality and insight in first-episode psychosis. Schizophr. Bull. 2011, 37(1):52-60.
12. Cannon-Spoor H.E., Potkin S.G., Wyatt R.J. Measurement of premorbid adjustment in chronic schizophrenia. Schizophr. Bull. 1982, 8(3):470-484.
13. Cegalis J.B.J. VIGIL: software for the assessment of attention 1991, Forthought, Nashua, NH.
14. Cuesta M.J., Peralta V., Zarzuela A., Zandio M. Insight dimensions and cognitive function in psychosis: a longitudinal study. BMC Psychiatry 2006, 6:26.
15. Cuesta M.J., Peralta V., Campos M.S., Garcia-Jalon E. Can insight be predicted in first-episode psychosis patients? A longitudinal and hierarchical analysis of predictors in a drug-naive sample. Schizophr. Res. 2011, 130(1-3):148-156.
16. Dantas C.R., Banzato C.E. Predictors of insight in psychotic inpatients. Schizophr. Res. 2007, 91(1-3):263-265.
17. David A.S. Insight and psychosis. Br. J. Psychiatry 1990, 156:798-808.
18. David A.S. The clinical importance of insight: an overview 2004, Oxford University Press, New York, NY. 2nd ed.
19. Debowska G., Grzywa A., Kucharska-Pietura K. Insight in paranoid schizophrenia-its relationship to psychopathology and premorbid adjustment. Compr. Psychiatry 1998, 39(5):255-260.
20. First M.B., Spitzer R.L., Gibbon M., Williams J.B.W. Structured Clinical Interview for DSM-IV Axis I Disorders, Clinician Version (SCID-CV) 1996, American Psychiatric Press, Inc., Washington, D.C.
21. Ghaemi S.N., Rosenquist K.J. Is insight in mania state-dependent?: A meta-analysis. J. Nerv. Ment. Dis. 2004, 192(11):771-775.
22. Gonzalez-Blanch C., Crespo-Facorro B., Alvarez-Jimenez M., Rodriguez-Sanchez J.M., Pelayo-Teran J.M., Perez-Iglesias R., Vazquez-Barquero J.L. Cognitive dimensions in first-episode schizophrenia spectrum disorders. J. Psychiatr. Res. 2007, 41(11):968-977.
23. Grube B.S., Bilder R.M., Goldman R.S. Meta-analysis of symptom factors in schizophrenia. Schizophr. Res. 1998, 31(2-3):113-120.
24. Hawton K., Sutton L., Haw C., Sinclair J., Deeks J.J. Schizophrenia and suicide: systematic review of risk factors. Br. J. Psychiatry 2005, 187:9-20.
25. Johnson S., Sathyaseelan M., Charles H., Jeyaseelan V., Jacob K.S. Predictors of insight in first-episode schizophrenia: a 5-year cohort study from India. Int. J. Soc. Psychiatry 2013, (October 4, 2013, Epub ahead of print). 10.1177/0020764013504561.
26. Kemp R., David A. Psychological predictors of insight and compliance in psychotic patients. Br. J. Psychiatry 1996, 169(4):444-450.
27. Keshavan M.S., Rabinowitz J., DeSmedt G., Harvey P.D., Schooler N. Correlates of insight in first episode psychosis. Schizophr. Res. 2004, 70(2-3):187-194.
28. Knowles E.E., David A.S., Reichenberg A. Processing speed deficits in schizophrenia: reexamining the evidence. Am. J. Psychiatry 2010, 167(7):828-835.
29. Lezak M.D. Neuropsychological assessment 1995, (New York). Press OU (Ed.).
30. Lincoln T.M., Lullmann E., Rief W. Correlates and long-term consequences of poor insight in patients with schizophrenia. A systematic review. Schizophr. Bull. 2007, 33(6):1324-1342.
31. Lopez-Morinigo J.D., Ramos-Rios R., David A.S., Dutta R. Insight in schizophrenia and risk of suicide: a systematic update. Compr. Psychiatry 2012, 53(4):313-322.
32. Lysaker P.H., Dimaggio G., Buck K.D., Callaway S.S., Salvatore G., Carcione A., Nicolo G., Stanghellini G. Poor insight in schizophrenia: links between different forms of metacognition with awareness of symptoms, treatment need, and consequences of illness. Compr. Psychiatry 2011, 52(3):253-260.
33. Mañá S., Ivorra J., Girón M. Adaptación y fiabilidad de la entrevista para la evaluación de la discapacidad social en pacientes psiquiátricos (OMS). Rev. Psiquiatr. Fac. Med. Barcelona 1998, 25(2):43-48.
34. McEvoy J.P., Johnson J., Perkins D., Lieberman J.A., Hamer R.M., Keefe R.S., Tohen M., Glick I.D., Sharma T. Insight in first-episode psychosis. Psychol. Med. 2006, 36(10):1385-1393.
35. McGorry P.D., Hickie I.B., Yung A.R., Pantelis C., Jackson H.J. Clinical staging of psychiatric disorders: a heuristic framework for choosing earlier, safer and more effective interventions. Aust. N. Z. J. Psychiatry 2006, 40(8):616-622.
36. Mintz A.R., Dobson K.S., Romney D.M. Insight in schizophrenia: a meta-analysis. Schizophr. Res. 2003, 61(1):75-88.
37. Mohamed S., Rosenheck R., McEvoy J., Swartz M., Stroup S., Lieberman J.A. Cross-sectional and longitudinal relationships between insight and attitudes toward medication and clinical outcomes in chronic schizophrenia. Schizophr. Bull. 2009, 35(2):336-346.
38. Osterrieth P.A. Contribution a l'étude de la perception et de la memoire. Arch. Psychol. 1944, 30:286-350.
39. Overall J.E.G.D. The brief psychiatric rating scale 1962, vol. 10.
40. Pelayo-Teran J.M., Perez-Iglesias R., Ramirez-Bonilla M., Gonzalez-Blanch C., Martinez-Garcia O., Pardo-Garcia G., Rodriguez-Sanchez J.M., Roiz-Santianez R., Tordesillas-Gutierrez D., Mata I., Vazquez-Barquero J.L., Crespo-Facorro B. Epidemiological factors associated with treated incidence of first-episode non-affective psychosis in Cantabria: insights from the Clinical Programme on Early Phases of Psychosis. Early Interv. Psychiatry 2008, 2(3):178-187.
41. Peralta V., Cuesta M.J. How many and which are the psychopathological dimensions in schizophrenia? Issues influencing their ascertainment. Schizophr. Res. 2001, 49(3):269-285.
42. Pijnenborg G.H., van Donkersgoed R.J., David A.S., Aleman A. Changes in insight during treatment for psychotic disorders: a meta-analysis. Schizophr. Res. 2013, 144(1-3):109-117.
43. Quee P.J., van der Meer L., Bruggeman R., de Haan L., Krabbendam L., Cahn W., Mulder N.C., Wiersma D., Aleman A. Insight in psychosis: relationship with neurocognition, social cognition and clinical symptoms depends on phase of illness. Schizophr. Bull. 2011, 37(1):29-37.
44. Reichenberg A., Harvey P.D., Bowie C.R., Mojtabai R., Rabinowitz J., Heaton R.K., Bromet E. Neuropsychological function and dysfunction in schizophrenia and psychotic affective disorders. Schizophr. Bull. 2009, 35(5):1022-1029.
45. Reitan R.M., Wolfson D. The Halstead-Reitan neuropsychological test battery: therapy and clinical interpretation 1985, Neuropsychological Press, Tucson, AZ.
46. Rey A. L'examen clinique en psychologie 1964, Presses Universitaires de France, Paris.
47. Saeedi H., Addington J., Addington D. The association of insight with psychotic symptoms, depression, and cognition in early psychosis: a 3-year follow-up. Schizophr. Res. 2007, 89(1-3):123-128.
48. Saravanan B., Jacob K.S., Johnson S., Prince M., Bhugra D., David A.S. Outcome of first-episode schizophrenia in India: longitudinal study of effect of insight and psychopathology. Br. J. Psychiatry 2010, 196(6):454-459.
49. Schennach R., Meyer S., Seemuller F., Jager M., Schmauss M., Laux G., Pfeiffer H., Naber D., Schmidt L.G., Gaebel W., Klosterkotter J., Heuser I., Maier W., Lemke M.R., Ruther E., Klingberg S., Gastpar M., Moller H.J., Riedel M. Insight in schizophrenia-course and predictors during the acute treatment phase of patients suffering from a schizophrenia spectrum disorder. Eur. Psychiatry 2012, 27(8):625-633.
50. Simon A.E., Berger G.E., Giacomini V., Ferrero F., Mohr S. Insight in relation to psychosocial adjustment in schizophrenia. J. Nerv. Ment. Dis. 2004, 192(6):442-445.
51. Weschsler D. Weschsler Adult Intelligence Scale-III 1997, The Psychological Corporation, San Antonio, TX.
52. Wiffen B.D., Rabinowitz J., Lex A., David A.S. Correlates, change and 'state or trait' properties of insight in schizophrenia. Schizophr. Res. 2010, 122(1-3):94-103.
53. Wiffen B.D., O'Connor J.A., Russo M., Lopez-Morinigo J.D., Ferraro L., Sideli L., Handley R., David A.S. Are there specific neuropsychological deficits underlying poor insight in first episode psychosis?. Schizophr. Res. 2012, 135(1-3):46-50.