메뉴 건너뛰기




Volumn 157, Issue 1-3, 2014, Pages 84-89

Potential role of the combination of galantamine and memantine to improve cognition in schizophrenia

Author keywords

Cognitive impairments; Galantamine; Memantine; Schizophrenia

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; BUNGAROTOXIN RECEPTOR; CHOLINESTERASE INHIBITOR; CLOZAPINE; CYCLOSERINE; DONEPEZIL; GALANTAMINE; GLYCINE; KYNURENINE; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PLACEBO; RISPERIDONE; RIVASTIGMINE; NOOTROPIC AGENT;

EID: 84904107880     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2014.04.037     Document Type: Review
Times cited : (51)

References (77)
  • 1
    • 84875001543 scopus 로고    scopus 로고
    • Early developmental elevations of brain kynurenic acid impair cognitive flexibility in adults: reversal with galantamine
    • Alexander K.S., Pocivavsek A., Wu H.Q., Pershing M.L., Schwarcz R., Bruno J.P. Early developmental elevations of brain kynurenic acid impair cognitive flexibility in adults: reversal with galantamine. Neuroscience 2013, 238:19-28.
    • (2013) Neuroscience , vol.238 , pp. 19-28
    • Alexander, K.S.1    Pocivavsek, A.2    Wu, H.Q.3    Pershing, M.L.4    Schwarcz, R.5    Bruno, J.P.6
  • 3
    • 84872399089 scopus 로고    scopus 로고
    • Memantine in patients with Alzheimer's disease receiving donepezil: new analyses of efficacy and safety for combination therapy
    • Atri A., Molinuevo J.L., Lemming O., Wirth Y., Pulte I., Wilkinson D. Memantine in patients with Alzheimer's disease receiving donepezil: new analyses of efficacy and safety for combination therapy. Alzheimers Res. Ther. 2013, 5(1):6.
    • (2013) Alzheimers Res. Ther. , vol.5 , Issue.1 , pp. 6
    • Atri, A.1    Molinuevo, J.L.2    Lemming, O.3    Wirth, Y.4    Pulte, I.5    Wilkinson, D.6
  • 4
    • 0033754407 scopus 로고    scopus 로고
    • Imaging the glutamatergic system in vivo-relevance to schizophrenia
    • Bressan R.A., Pilowsky L.S. Imaging the glutamatergic system in vivo-relevance to schizophrenia. Eur. J. Nucl. Med. 2000, 27(11):1723-1731.
    • (2000) Eur. J. Nucl. Med. , vol.27 , Issue.11 , pp. 1723-1731
    • Bressan, R.A.1    Pilowsky, L.S.2
  • 6
    • 34548321168 scopus 로고    scopus 로고
    • Recent advances in the development of novel pharmacological agents for the treatment of cognitive impairments in schizophrenia
    • Buchanan R.W., Freedman R., Javitt D.C., Abi-Dargham A., Lieberman J.A. Recent advances in the development of novel pharmacological agents for the treatment of cognitive impairments in schizophrenia. Schizophr. Bull. 2007, 33(5):1120-1130.
    • (2007) Schizophr. Bull. , vol.33 , Issue.5 , pp. 1120-1130
    • Buchanan, R.W.1    Freedman, R.2    Javitt, D.C.3    Abi-Dargham, A.4    Lieberman, J.A.5
  • 7
    • 35748969317 scopus 로고    scopus 로고
    • The Cognitive and Negative Symptoms in Schizophrenia Trial (CONSIST): the efficacy of glutamatergic agents for negative symptoms and cognitive impairments
    • Buchanan R.W., Javitt D.C., Marder S.R., Schooler N.R., Gold J.M., McMahon R.P., Heresco-Levy U., Carpenter W.T. The Cognitive and Negative Symptoms in Schizophrenia Trial (CONSIST): the efficacy of glutamatergic agents for negative symptoms and cognitive impairments. Am. J. Psychiatry 2007, 164(10):1593-1602.
    • (2007) Am. J. Psychiatry , vol.164 , Issue.10 , pp. 1593-1602
    • Buchanan, R.W.1    Javitt, D.C.2    Marder, S.R.3    Schooler, N.R.4    Gold, J.M.5    McMahon, R.P.6    Heresco-Levy, U.7    Carpenter, W.T.8
  • 9
    • 0043172479 scopus 로고    scopus 로고
    • The glutamatergic system and Alzheimer's disease: therapeutic implications
    • Butterfield D.A., Pocernich C.B. The glutamatergic system and Alzheimer's disease: therapeutic implications. CNS Drugs 2003, 17(9):641-652.
    • (2003) CNS Drugs , vol.17 , Issue.9 , pp. 641-652
    • Butterfield, D.A.1    Pocernich, C.B.2
  • 13
    • 0242499301 scopus 로고    scopus 로고
    • The genetics of schizophrenia: glutamate not dopamine?
    • Collier D.A., Li T. The genetics of schizophrenia: glutamate not dopamine?. Eur. J. Pharmacol. 2003, 480(1-3):177-184.
    • (2003) Eur. J. Pharmacol. , vol.480 , Issue.1-3 , pp. 177-184
    • Collier, D.A.1    Li, T.2
  • 14
    • 0037942706 scopus 로고    scopus 로고
    • Ionotropic glutamate receptors as therapeutic targets in schizophrenia
    • Coyle J.T., Tsai G., Goff D.C. Ionotropic glutamate receptors as therapeutic targets in schizophrenia. Curr. Drug Targets CNS Neurol. Disord. 2002, 1(2):183-189.
    • (2002) Curr. Drug Targets CNS Neurol. Disord. , vol.1 , Issue.2 , pp. 183-189
    • Coyle, J.T.1    Tsai, G.2    Goff, D.C.3
  • 16
    • 17744365167 scopus 로고    scopus 로고
    • Impairment in perceptual attentional set-shifting following PCP administration: a rodent model of set-shifting deficits in schizophrenia
    • Egerton A., Reid L., McKerchar C.E., Morris B.J., Pratt J.A. Impairment in perceptual attentional set-shifting following PCP administration: a rodent model of set-shifting deficits in schizophrenia. Psychopharmacology (Berl) 2005, 179(1):77-84.
    • (2005) Psychopharmacology (Berl) , vol.179 , Issue.1 , pp. 77-84
    • Egerton, A.1    Reid, L.2    McKerchar, C.E.3    Morris, B.J.4    Pratt, J.A.5
  • 17
    • 0035798252 scopus 로고    scopus 로고
    • Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia
    • Erhardt S., Blennow K., Nordin C., Skogh E., Lindstrom L.H., Engberg G. Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia. Neurosci. Lett. 2001, 313(1-2):96-98.
    • (2001) Neurosci. Lett. , vol.313 , Issue.1-2 , pp. 96-98
    • Erhardt, S.1    Blennow, K.2    Nordin, C.3    Skogh, E.4    Lindstrom, L.H.5    Engberg, G.6
  • 18
    • 33846815311 scopus 로고    scopus 로고
    • Effects of donepezil adjunctive treatment to ziprasidone on cognitive deficits in schizophrenia: a double-blind, placebo-controlled study
    • Fagerlund B., Soholm B., Fink-Jensen A., Lublin H., Glenthoj B.Y. Effects of donepezil adjunctive treatment to ziprasidone on cognitive deficits in schizophrenia: a double-blind, placebo-controlled study. Clin. Neuropharmacol. 2007, 30(1):3-12.
    • (2007) Clin. Neuropharmacol. , vol.30 , Issue.1 , pp. 3-12
    • Fagerlund, B.1    Soholm, B.2    Fink-Jensen, A.3    Lublin, H.4    Glenthoj, B.Y.5
  • 20
    • 0036501411 scopus 로고    scopus 로고
    • A double blind placebo controlled trial of donepezil adjunctive treatment to risperidone for the cognitive impairment of schizophrenia
    • Friedman J.I., Adler D.N., Howanitz E., Harvey P.D., Brenner G., Temporini H., White L., Parrella M., Davis K.L. A double blind placebo controlled trial of donepezil adjunctive treatment to risperidone for the cognitive impairment of schizophrenia. Biol. Psychiatry 2002, 51(5):349-357.
    • (2002) Biol. Psychiatry , vol.51 , Issue.5 , pp. 349-357
    • Friedman, J.I.1    Adler, D.N.2    Howanitz, E.3    Harvey, P.D.4    Brenner, G.5    Temporini, H.6    White, L.7    Parrella, M.8    Davis, K.L.9
  • 21
    • 0034704207 scopus 로고    scopus 로고
    • Cholinergic enhancement and increased selectivity of perceptual processing during working memory
    • Furey M.L., Pietrini P., Haxby J.V. Cholinergic enhancement and increased selectivity of perceptual processing during working memory. Science 2000, 290(5500):2315-2319.
    • (2000) Science , vol.290 , Issue.5500 , pp. 2315-2319
    • Furey, M.L.1    Pietrini, P.2    Haxby, J.V.3
  • 22
    • 33745072134 scopus 로고    scopus 로고
    • Pharmacology of acetylcholinesterase inhibitors and N-methyl-D-aspartate receptors for combination therapy in the treatment of Alzheimer's disease
    • Geerts H., Grossberg G.T. Pharmacology of acetylcholinesterase inhibitors and N-methyl-D-aspartate receptors for combination therapy in the treatment of Alzheimer's disease. J. Clin. Pharmacol. 2006, 46(7 Suppl. 1):8S-16S.
    • (2006) J. Clin. Pharmacol. , vol.46 , Issue.7 SUPPL. 1
    • Geerts, H.1    Grossberg, G.T.2
  • 24
    • 0038215374 scopus 로고    scopus 로고
    • Tolerance, DCs and tryptophan: much ado about IDO
    • Grohmann U., Fallarino F., Puccetti P. Tolerance, DCs and tryptophan: much ado about IDO. Trends Immunol. 2003, 24(5):242-248.
    • (2003) Trends Immunol. , vol.24 , Issue.5 , pp. 242-248
    • Grohmann, U.1    Fallarino, F.2    Puccetti, P.3
  • 25
    • 33745102766 scopus 로고    scopus 로고
    • Rationale for combination therapy with galantamine and memantine in Alzheimer's disease
    • Grossberg G.T., Edwards K.R., Zhao Q. Rationale for combination therapy with galantamine and memantine in Alzheimer's disease. J. Clin. Pharmacol. 2006, 46(7 Suppl. 1):17S-26S.
    • (2006) J. Clin. Pharmacol. , vol.46 , Issue.7 SUPPL. 1
    • Grossberg, G.T.1    Edwards, K.R.2    Zhao, Q.3
  • 27
    • 0035478066 scopus 로고    scopus 로고
    • The brain metabolite kynurenic acid inhibits α7 nicotinic receptor activity and increases non-α7 nicotinic receptor expression: physiopathological implications
    • Hilmas C., Pereira E.F., Alkondon M., Rassoulpour A., Schwarcz R., Albuquerque E.X. The brain metabolite kynurenic acid inhibits α7 nicotinic receptor activity and increases non-α7 nicotinic receptor expression: physiopathological implications. J. Neurosci. 2001, 21(19):7463-7473.
    • (2001) J. Neurosci. , vol.21 , Issue.19 , pp. 7463-7473
    • Hilmas, C.1    Pereira, E.F.2    Alkondon, M.3    Rassoulpour, A.4    Schwarcz, R.5    Albuquerque, E.X.6
  • 28
    • 35548991088 scopus 로고    scopus 로고
    • NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons
    • Homayoun H., Moghaddam B. NMDA receptor hypofunction produces opposite effects on prefrontal cortex interneurons and pyramidal neurons. J. Neurosci. 2007, 27(43):11496-11500.
    • (2007) J. Neurosci. , vol.27 , Issue.43 , pp. 11496-11500
    • Homayoun, H.1    Moghaddam, B.2
  • 29
    • 54249155522 scopus 로고    scopus 로고
    • Network pharmacology: the next paradigm in drug discovery
    • Hopkins A.L. Network pharmacology: the next paradigm in drug discovery. Nat. Chem. Biol. 2008, 4(11):682-690.
    • (2008) Nat. Chem. Biol. , vol.4 , Issue.11 , pp. 682-690
    • Hopkins, A.L.1
  • 30
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • Javitt D.C., Zukin S.R. Recent advances in the phencyclidine model of schizophrenia. Am. J. Psychiatry 1991, 148(10):1301-1308.
    • (1991) Am. J. Psychiatry , vol.148 , Issue.10 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 31
    • 42049123448 scopus 로고    scopus 로고
    • Efficacy and safety of donepezil in patients with schizophrenia or schizoaffective disorder: significant placebo/practice effects in a 12-week, randomized, double-blind, placebo-controlled trial
    • Keefe R.S., Malhotra A.K., Meltzer H.Y., Kane J.M., Buchanan R.W., Murthy A., Sovel M., Li C., Goldman R. Efficacy and safety of donepezil in patients with schizophrenia or schizoaffective disorder: significant placebo/practice effects in a 12-week, randomized, double-blind, placebo-controlled trial. Neuropsychopharmacology 2008, 33(6):1217-1228.
    • (2008) Neuropsychopharmacology , vol.33 , Issue.6 , pp. 1217-1228
    • Keefe, R.S.1    Malhotra, A.K.2    Meltzer, H.Y.3    Kane, J.M.4    Buchanan, R.W.5    Murthy, A.6    Sovel, M.7    Li, C.8    Goldman, R.9
  • 34
    • 84880133046 scopus 로고    scopus 로고
    • NMDA receptor antagonists interventions in schizophrenia: meta-analysis of randomized, placebo-controlled trials
    • Kishi T., Iwata N. NMDA receptor antagonists interventions in schizophrenia: meta-analysis of randomized, placebo-controlled trials. J. Psychiatr. Res. 2013, 47(9):1143-1149.
    • (2013) J. Psychiatr. Res. , vol.47 , Issue.9 , pp. 1143-1149
    • Kishi, T.1    Iwata, N.2
  • 35
    • 82955246636 scopus 로고    scopus 로고
    • Case report on the management of depression in schizoaffective disorder, bipolar type focusing on lithium levels and measurement-based care
    • Koola M.M., Fawcett J.A., Kelly D.L. Case report on the management of depression in schizoaffective disorder, bipolar type focusing on lithium levels and measurement-based care. J. Nerv. Ment. Dis. 2011, 199(12):989-990.
    • (2011) J. Nerv. Ment. Dis. , vol.199 , Issue.12 , pp. 989-990
    • Koola, M.M.1    Fawcett, J.A.2    Kelly, D.L.3
  • 36
    • 84998075618 scopus 로고    scopus 로고
    • High-dose prazosin for the treatment of post-traumatic stress disorder
    • Koola M.M., Varghese S.P., Fawcett J.A. High-dose prazosin for the treatment of post-traumatic stress disorder. Ther. Adv. Psychopharmacol. 2014, 4(1):43-47.
    • (2014) Ther. Adv. Psychopharmacol. , vol.4 , Issue.1 , pp. 43-47
    • Koola, M.M.1    Varghese, S.P.2    Fawcett, J.A.3
  • 38
    • 0035977703 scopus 로고    scopus 로고
    • The effect of nicotine and haloperidol co-treatment on nicotinic receptor levels in the rat brain
    • Lee M.J., Breese C.R., Strook M.L., Leonard S. The effect of nicotine and haloperidol co-treatment on nicotinic receptor levels in the rat brain. Brain Res. Mol. Brain Res. 2001, 86(1-2):115-124.
    • (2001) Brain Res. Mol. Brain Res. , vol.86 , Issue.1-2 , pp. 115-124
    • Lee, M.J.1    Breese, C.R.2    Strook, M.L.3    Leonard, S.4
  • 39
    • 33846986313 scopus 로고    scopus 로고
    • A 12-week, double-blind, placebo-controlled trial of galantamine adjunctive treatment to conventional antipsychotics for the cognitive impairments in chronic schizophrenia
    • Lee S.W., Lee J.G., Lee B.J., Kim Y.H. A 12-week, double-blind, placebo-controlled trial of galantamine adjunctive treatment to conventional antipsychotics for the cognitive impairments in chronic schizophrenia. Int. Clin. Psychopharmacol. 2007, 22(2):63-68.
    • (2007) Int. Clin. Psychopharmacol. , vol.22 , Issue.2 , pp. 63-68
    • Lee, S.W.1    Lee, J.G.2    Lee, B.J.3    Kim, Y.H.4
  • 40
    • 84863429650 scopus 로고    scopus 로고
    • Adjunctive memantine therapy for cognitive impairment in chronic schizophrenia: a placebo-controlled pilot study
    • Lee J.G., Lee S.W., Lee B.J., Park S.W., Kim G.M., Kim Y.H. Adjunctive memantine therapy for cognitive impairment in chronic schizophrenia: a placebo-controlled pilot study. Psychiatry Invest. 2012, 9(2):166-173.
    • (2012) Psychiatry Invest. , vol.9 , Issue.2 , pp. 166-173
    • Lee, J.G.1    Lee, S.W.2    Lee, B.J.3    Park, S.W.4    Kim, G.M.5    Kim, Y.H.6
  • 41
  • 42
    • 78951485005 scopus 로고    scopus 로고
    • Galantamine augmentation of long-acting injectable risperidone for cognitive impairments in chronic schizophrenia
    • Lindenmayer J.P., Khan A. Galantamine augmentation of long-acting injectable risperidone for cognitive impairments in chronic schizophrenia. Schizophr. Res. 2011, 125(2-3):267-277.
    • (2011) Schizophr. Res. , vol.125 , Issue.2-3 , pp. 267-277
    • Lindenmayer, J.P.1    Khan, A.2
  • 43
    • 84893466236 scopus 로고    scopus 로고
    • Galantamine potentiates the neuroprotective effect of memantine against NMDA-induced excitotoxicity
    • Lopes J.P., Tarozzo G., Reggiani A., Piomelli D., Cavalli A. Galantamine potentiates the neuroprotective effect of memantine against NMDA-induced excitotoxicity. Brain Behav. 2013, 3(2):67-74.
    • (2013) Brain Behav. , vol.3 , Issue.2 , pp. 67-74
    • Lopes, J.P.1    Tarozzo, G.2    Reggiani, A.3    Piomelli, D.4    Cavalli, A.5
  • 44
    • 0036662935 scopus 로고    scopus 로고
    • Control of feedforward dendritic inhibition by NMDA receptor-dependent spike timing in hippocampal interneurons
    • Maccaferri G., Dingledine R. Control of feedforward dendritic inhibition by NMDA receptor-dependent spike timing in hippocampal interneurons. J. Neurosci. 2002, 22(13):5462-5472.
    • (2002) J. Neurosci. , vol.22 , Issue.13 , pp. 5462-5472
    • Maccaferri, G.1    Dingledine, R.2
  • 46
    • 0030900732 scopus 로고    scopus 로고
    • Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex
    • Moghaddam B., Adams B., Verma A., Daly D. Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J. Neurosci. 1997, 17(8):2921-2927.
    • (1997) J. Neurosci. , vol.17 , Issue.8 , pp. 2921-2927
    • Moghaddam, B.1    Adams, B.2    Verma, A.3    Daly, D.4
  • 47
    • 33846574259 scopus 로고    scopus 로고
    • Fragments, network biology and designing multiple ligands
    • Morphy R., Rankovic Z. Fragments, network biology and designing multiple ligands. Drug Discov. Today 2007, 12(3-4):156-160.
    • (2007) Drug Discov. Today , vol.12 , Issue.3-4 , pp. 156-160
    • Morphy, R.1    Rankovic, Z.2
  • 48
    • 0027031286 scopus 로고
    • Neuroreceptor changes in Alzheimer disease
    • Nordberg A. Neuroreceptor changes in Alzheimer disease. Cerebrovasc. Brain Metab. Rev. 1992, 4(4):303-328.
    • (1992) Cerebrovasc. Brain Metab. Rev. , vol.4 , Issue.4 , pp. 303-328
    • Nordberg, A.1
  • 50
    • 0025282045 scopus 로고
    • Is the neuronal basis of Alzheimer's disease cholinergic or glutamatergic?
    • Palmer A.M., Gershon S. Is the neuronal basis of Alzheimer's disease cholinergic or glutamatergic?. FASEB J. 1990, 4(10):2745-2752.
    • (1990) FASEB J. , vol.4 , Issue.10 , pp. 2745-2752
    • Palmer, A.M.1    Gershon, S.2
  • 52
    • 34948842904 scopus 로고    scopus 로고
    • Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system-too little activation is bad, too much is even worse
    • Parsons C.G., Stoffler A., Danysz W. Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system-too little activation is bad, too much is even worse. Neuropharmacology 2007, 53(6):699-723.
    • (2007) Neuropharmacology , vol.53 , Issue.6 , pp. 699-723
    • Parsons, C.G.1    Stoffler, A.2    Danysz, W.3
  • 53
    • 84883459353 scopus 로고    scopus 로고
    • Memantine and cholinesterase inhibitors: complementary mechanisms in the treatment of Alzheimer's disease
    • Parsons C.G., Danysz W., Dekundy A., Pulte I. Memantine and cholinesterase inhibitors: complementary mechanisms in the treatment of Alzheimer's disease. Neurotox. Res. 2013, 24(3):358-369.
    • (2013) Neurotox. Res. , vol.24 , Issue.3 , pp. 358-369
    • Parsons, C.G.1    Danysz, W.2    Dekundy, A.3    Pulte, I.4
  • 56
    • 0141954291 scopus 로고    scopus 로고
    • The neuropharmacological basis for the use of memantine in the treatment of Alzheimer's disease
    • Rogawski M.A., Wenk G.L. The neuropharmacological basis for the use of memantine in the treatment of Alzheimer's disease. CNS Drug Rev. 2003, 9(3):275-308.
    • (2003) CNS Drug Rev. , vol.9 , Issue.3 , pp. 275-308
    • Rogawski, M.A.1    Wenk, G.L.2
  • 58
    • 0036232874 scopus 로고    scopus 로고
    • The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system
    • Santos M.D., Alkondon M., Pereira E.F., Aracava Y., Eisenberg H.M., Maelicke A., Albuquerque E.X. The nicotinic allosteric potentiating ligand galantamine facilitates synaptic transmission in the mammalian central nervous system. Mol. Pharmacol. 2002, 61(5):1222-1234.
    • (2002) Mol. Pharmacol. , vol.61 , Issue.5 , pp. 1222-1234
    • Santos, M.D.1    Alkondon, M.2    Pereira, E.F.3    Aracava, Y.4    Eisenberg, H.M.5    Maelicke, A.6    Albuquerque, E.X.7
  • 59
    • 33845712062 scopus 로고    scopus 로고
    • Galantamine enhances dopaminergic neurotransmission in vivo via allosteric potentiation of nicotinic acetylcholine receptors
    • Schilstrom B., Ivanov V.B., Wiker C., Svensson T.H. Galantamine enhances dopaminergic neurotransmission in vivo via allosteric potentiation of nicotinic acetylcholine receptors. Neuropsychopharmacology 2007, 32(1):43-53.
    • (2007) Neuropsychopharmacology , vol.32 , Issue.1 , pp. 43-53
    • Schilstrom, B.1    Ivanov, V.B.2    Wiker, C.3    Svensson, T.H.4
  • 60
    • 33748751285 scopus 로고    scopus 로고
    • Galantamine improves cognition in schizophrenic patients stabilized on risperidone
    • Schubert M.H., Young K.A., Hicks P.B. Galantamine improves cognition in schizophrenic patients stabilized on risperidone. Biol. Psychiatry 2006, 60(6):530-533.
    • (2006) Biol. Psychiatry , vol.60 , Issue.6 , pp. 530-533
    • Schubert, M.H.1    Young, K.A.2    Hicks, P.B.3
  • 61
    • 32844460508 scopus 로고    scopus 로고
    • What is the recommended approach to asymptomatic patients who develop a reactive PPD?
    • (discussion 163)
    • Sharma U., Morris C., Safranek S. What is the recommended approach to asymptomatic patients who develop a reactive PPD?. J. Fam. Pract. 2006, 55(2):163-165. (discussion 163).
    • (2006) J. Fam. Pract. , vol.55 , Issue.2 , pp. 163-165
    • Sharma, U.1    Morris, C.2    Safranek, S.3
  • 63
    • 36148957186 scopus 로고    scopus 로고
    • A review of compliance to treatment in Alzheimer's disease: potential benefits of a transdermal patch
    • Small G., Dubois B. A review of compliance to treatment in Alzheimer's disease: potential benefits of a transdermal patch. Curr. Med. Res. Opin. 2007, 23(11):2705-2713.
    • (2007) Curr. Med. Res. Opin. , vol.23 , Issue.11 , pp. 2705-2713
    • Small, G.1    Dubois, B.2
  • 64
    • 0027486072 scopus 로고
    • Neuropharmacology of quinolinic and kynurenic acids
    • Stone T.W. Neuropharmacology of quinolinic and kynurenic acids. Pharmacol. Rev. 1993, 45(3):309-379.
    • (1993) Pharmacol. Rev. , vol.45 , Issue.3 , pp. 309-379
    • Stone, T.W.1
  • 65
    • 0345872128 scopus 로고    scopus 로고
    • Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial
    • Tariot P.N., Farlow M.R., Grossberg G.T., Graham S.M., McDonald S., Gergel I. Memantine treatment in patients with moderate to severe Alzheimer disease already receiving donepezil: a randomized controlled trial. JAMA 2004, 291(3):317-324.
    • (2004) JAMA , vol.291 , Issue.3 , pp. 317-324
    • Tariot, P.N.1    Farlow, M.R.2    Grossberg, G.T.3    Graham, S.M.4    McDonald, S.5    Gergel, I.6
  • 67
    • 17544402307 scopus 로고    scopus 로고
    • A double-blind, placebo controlled, cross-over trial of adjunctive donepezil for cognitive impairment in schizophrenia
    • Tugal O., Yazici K.M., Anil Yagcioglu A.E., Gogus A. A double-blind, placebo controlled, cross-over trial of adjunctive donepezil for cognitive impairment in schizophrenia. Int. J. Neuropsychopharmacol. 2004, 7(2):117-123.
    • (2004) Int. J. Neuropsychopharmacol. , vol.7 , Issue.2 , pp. 117-123
    • Tugal, O.1    Yazici, K.M.2    Anil Yagcioglu, A.E.3    Gogus, A.4
  • 68
    • 12344307021 scopus 로고    scopus 로고
    • Acute vagotomy activates the cholinergic anti-inflammatory pathway
    • (author reply H978-9)
    • van Westerloo D., van der Poll T. Acute vagotomy activates the cholinergic anti-inflammatory pathway. Am. J. Physiol. Heart Circ. Physiol. 2005, 288(2):H977-H978. (author reply H978-9).
    • (2005) Am. J. Physiol. Heart Circ. Physiol. , vol.288 , Issue.2
    • van Westerloo, D.1    van der Poll, T.2
  • 69
    • 69949103030 scopus 로고    scopus 로고
    • The cognitive cost of anticholinergic burden: decreased response to cognitive training in schizophrenia
    • Vinogradov S., Fisher M., Warm H., Holland C., Kirshner M.A., Pollock B.G. The cognitive cost of anticholinergic burden: decreased response to cognitive training in schizophrenia. Am. J. Psychiatry 2009, 166(9):1055-1062.
    • (2009) Am. J. Psychiatry , vol.166 , Issue.9 , pp. 1055-1062
    • Vinogradov, S.1    Fisher, M.2    Warm, H.3    Holland, C.4    Kirshner, M.A.5    Pollock, B.G.6
  • 70
    • 33846672364 scopus 로고    scopus 로고
    • Genetic evidence for ongoing balanced selection at human DNA repair genes ERCC8, FANCC, and RAD51C
    • Wang E.T., Moyzis R.K. Genetic evidence for ongoing balanced selection at human DNA repair genes ERCC8, FANCC, and RAD51C. Mutat. Res. 2007, 616(1-2):165-174.
    • (2007) Mutat. Res. , vol.616 , Issue.1-2 , pp. 165-174
    • Wang, E.T.1    Moyzis, R.K.2
  • 71
    • 0034635589 scopus 로고    scopus 로고
    • No interaction of memantine with acetylcholinesterase inhibitors approved for clinical use
    • Wenk G.L., Quack G., Moebius H.J., Danysz W. No interaction of memantine with acetylcholinesterase inhibitors approved for clinical use. Life Sci. 2000, 66(12):1079-1083.
    • (2000) Life Sci. , vol.66 , Issue.12 , pp. 1079-1083
    • Wenk, G.L.1    Quack, G.2    Moebius, H.J.3    Danysz, W.4
  • 72
    • 84895813884 scopus 로고    scopus 로고
    • Chronic and bedtime use of benztropine with antipsychotics: is it necessary?
    • Wijegunaratne H., Qazi H., Koola M.M. Chronic and bedtime use of benztropine with antipsychotics: is it necessary?. Schizophr. Res. 2014, 153(1-3):248-249.
    • (2014) Schizophr. Res. , vol.153 , Issue.1-3 , pp. 248-249
    • Wijegunaratne, H.1    Qazi, H.2    Koola, M.M.3
  • 73
    • 77749242786 scopus 로고    scopus 로고
    • Cortical kynurenine pathway metabolism: a novel target for cognitive enhancement in schizophrenia
    • Wonodi I., Schwarcz R. Cortical kynurenine pathway metabolism: a novel target for cognitive enhancement in schizophrenia. Schizophr. Bull. 2010, 36(2):211-218.
    • (2010) Schizophr. Bull. , vol.36 , Issue.2 , pp. 211-218
    • Wonodi, I.1    Schwarcz, R.2
  • 74
    • 25144449608 scopus 로고    scopus 로고
    • Targeting prefrontal cortical dopamine D1 and N-methyl-d-aspartate receptor interactions in schizophrenia treatment
    • Yang C.R., Chen L. Targeting prefrontal cortical dopamine D1 and N-methyl-d-aspartate receptor interactions in schizophrenia treatment. Neuroscientist 2005, 11(5):452-470.
    • (2005) Neuroscientist , vol.11 , Issue.5 , pp. 452-470
    • Yang, C.R.1    Chen, L.2
  • 76
    • 33750813865 scopus 로고    scopus 로고
    • In vitro galantamine-memantine co-application: mechanism of beneficial action
    • Zhao X., Marszalec W., Toth P.T., Huang J., Yeh J.Z., Narahashi T. In vitro galantamine-memantine co-application: mechanism of beneficial action. Neuropharmacology 2006, 51(7-8):1181-1191.
    • (2006) Neuropharmacology , vol.51 , Issue.7-8 , pp. 1181-1191
    • Zhao, X.1    Marszalec, W.2    Toth, P.T.3    Huang, J.4    Yeh, J.Z.5    Narahashi, T.6
  • 77
    • 33845762340 scopus 로고    scopus 로고
    • Multi-target therapeutics: when the whole is greater than the sum of the parts
    • Zimmermann G.R., Lehar J., Keith C.T. Multi-target therapeutics: when the whole is greater than the sum of the parts. Drug Discov. Today 2007, 12(1-2):34-42.
    • (2007) Drug Discov. Today , vol.12 , Issue.1-2 , pp. 34-42
    • Zimmermann, G.R.1    Lehar, J.2    Keith, C.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.