메뉴 건너뛰기




Volumn 13, Issue 1, 2014, Pages

Metformin enhances nitric oxide production and diminishes Rho kinase activity in rats with hyperlipidemia

Author keywords

Hyperlipidemia; Nitric oxide; Rho kinase

Indexed keywords

ATORVASTATIN; C REACTIVE PROTEIN; HEPTANOIC ACID DERIVATIVE; HYPOCHOLESTEROLEMIC AGENT; METFORMIN; NITRIC OXIDE; PYRROLE DERIVATIVE; RHO KINASE;

EID: 84904078023     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-13-115     Document Type: Article
Times cited : (29)

References (32)
  • 1
    • 84888767557 scopus 로고    scopus 로고
    • 2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
    • S0735-1097
    • - 2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Goff DC Jr, Lloyd-Jones DM, Bennett G, O'Donnell CJ, Coady S, Robinson J, D'Agostino RB Sr, Schwartz JS, Gibbons R, Shero ST, Greenland P, Smith SC Jr, Lackland DT, Sorlie P, Levy D, Stone NJ, Wilson PW, J Am Coll Cardiol 2013 S0735-1097 13 06031 06032
    • (2013) J Am Coll Cardiol , Issue.13 , pp. 06031-06032
    • Goff Jr., D.C.1    Lloyd-Jones, D.M.2    Bennett, G.3    O'Donnell, C.J.4    Coady, S.5    Robinson, J.6    D'Agostino Sr., R.B.7    Schwartz, J.S.8    Gibbons, R.9    Shero, S.T.10    Greenland, P.11
  • 2
    • 38049033935 scopus 로고    scopus 로고
    • Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: A meta-analysis
    • Efficacy of cholesterol-lowering therapy in 18,686 people with diabetes in 14 randomised trials of statins: a meta-analysis. Kearney PM, Blackwell L, Collins R, Keech A, Simes J, Peto R, Armitage J, Baigent C, Lancet 2008 371 117 125
    • (2008) Lancet , vol.371 , pp. 117-125
    • Kearney, P.M.1    Blackwell, L.2    Collins, R.3    Keech, A.4    Simes, J.5    Peto, R.6    Armitage, J.7    Baigent, C.8
  • 4
    • 0033398822 scopus 로고    scopus 로고
    • Simvastatin inhibits leukocyte-endothelial cell interactions and protects against inflammatory processes in normocholesterolemic rats
    • Simvastatin inhibits leukocyte-endothelial cell interactions and protects against inflammatory processes in normocholesterolemic rats. Pruefer D, Scalia R, Lefer AM, Arterioscler Thromb Vasc Biol 1999 19 2894 2900 (Pubitemid 30029815)
    • (1999) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.19 , Issue.12 , pp. 2894-2900
    • Pruefer, D.1    Scalia, R.2    Lefer, A.M.3
  • 5
    • 33746473678 scopus 로고    scopus 로고
    • Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages
    • DOI 10.1016/j.atherosclerosis.2005.10.015, PII S0021915005006660
    • Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages. Veillard NR, Braunersreuther V, Arnaud C, Burger F, Pelli G, Steffens S, Mach F, Atherosclerosis 2006 188 51 58 (Pubitemid 44142533)
    • (2006) Atherosclerosis , vol.188 , Issue.1 , pp. 51-58
    • Veillard, N.R.1    Braunersreuther, V.2    Arnaud, C.3    Burger, F.4    Pelli, G.5    Steffens, S.6    Mach, F.7
  • 6
    • 84857694797 scopus 로고    scopus 로고
    • Statins as anti-inflammatory agents in atherogenesis: Molecular mechanisms and lessons from the recent clinical trials
    • Statins as anti-inflammatory agents in atherogenesis: molecular mechanisms and lessons from the recent clinical trials. Antonopoulos AS, Margaritis M, Lee R, Channon K, Antoniades C, Curr Pharm Des 2012 18 1519 1530
    • (2012) Curr Pharm des , vol.18 , pp. 1519-1530
    • Antonopoulos, A.S.1    Margaritis, M.2    Lee, R.3    Channon, K.4    Antoniades, C.5
  • 8
    • 84894438924 scopus 로고    scopus 로고
    • Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis
    • Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis. Sawada N, Liao JK, Antioxid Redox Signal 2014 20 1251 1267
    • (2014) Antioxid Redox Signal , vol.20 , pp. 1251-1267
    • Sawada, N.1    Liao, J.K.2
  • 9
    • 84885900541 scopus 로고    scopus 로고
    • Small G proteins in the cardiovascular system: Physiological and pathological aspects
    • Small G proteins in the cardiovascular system: physiological and pathological aspects. Loirand G, Sauzeau V, Pacaud P, Physiol Rev 2013 93 1659 1720
    • (2013) Physiol Rev , vol.93 , pp. 1659-1720
    • Loirand, G.1    Sauzeau, V.2    Pacaud, P.3
  • 10
    • 34047260912 scopus 로고    scopus 로고
    • Increased Rho Kinase Activity in a Taiwanese Population With Metabolic Syndrome
    • DOI 10.1016/j.jacc.2006.12.043, PII S0735109707004305
    • Increased Rho kinase activity in a Taiwanese population with metabolic syndrome. Liu PY, Chen JH, Lin LJ, Liao JK, J Am Coll Cardiol 2007 49 1619 1624 (Pubitemid 46551629)
    • (2007) Journal of the American College of Cardiology , vol.49 , Issue.15 , pp. 1619-1624
    • Liu, P.-Y.1    Chen, J.-H.2    Lin, L.-J.3    Liao, J.K.4
  • 12
    • 59049103155 scopus 로고    scopus 로고
    • Evidence for statin pleiotropy in humans: Differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation
    • Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation. Liu PY, Liu YW, Lin LJ, Chen JH, Liao JK, Circulation 2009 119 131 138
    • (2009) Circulation , vol.119 , pp. 131-138
    • Liu, P.Y.1    Liu, Y.W.2    Lin, L.J.3    Chen, J.H.4    Liao, J.K.5
  • 13
    • 59049108097 scopus 로고    scopus 로고
    • Comparison of effects of rosuvastatin (10 mg) versus atorvastatin (40 mg) on rho kinase activity in caucasian men with a previous atherosclerotic event
    • Comparison of effects of rosuvastatin (10 mg) versus atorvastatin (40 mg) on rho kinase activity in caucasian men with a previous atherosclerotic event. Rawlings R, Nohria A, Liu PY, Donnelly J, Creager MA, Ganz P, Selwyn A, Liao JK, Am J Cardiol 2009 103 437 441
    • (2009) Am J Cardiol , vol.103 , pp. 437-441
    • Rawlings, R.1    Nohria, A.2    Liu, P.Y.3    Donnelly, J.4    Creager, M.A.5    Ganz, P.6    Selwyn, A.7    Liao, J.K.8
  • 15
    • 40949087724 scopus 로고    scopus 로고
    • Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling
    • Acute metformin therapy confers cardioprotection against myocardial infarction via AMPK-eNOS-mediated signaling. Calvert JW, Gundewar S, Jha S, Greer JJ, Bestermann WH, Tian R, Lefer DJ, Diabetes 2008 57 696 705
    • (2008) Diabetes , vol.57 , pp. 696-705
    • Calvert, J.W.1    Gundewar, S.2    Jha, S.3    Greer, J.J.4    Bestermann, W.H.5    Tian, R.6    Lefer, D.J.7
  • 17
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-an inflammatory disease
    • Atherosclerosis-an inflammatory disease. Ross R, N Engl J Med 1999 340 115 126
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 18
    • 84881063410 scopus 로고    scopus 로고
    • NICE guideline on lipid modification
    • NICE guideline on lipid modification. Jaques H, Eur Heart J 2013 34 481 482
    • (2013) Eur Heart J , vol.34 , pp. 481-482
    • Jaques, H.1
  • 20
    • 84899940001 scopus 로고    scopus 로고
    • Synergistic effects of colchicine combined with atorvastatin in rats with hyperlipidemia
    • Synergistic effects of colchicine combined with atorvastatin in rats with hyperlipidemia. Huang C, Ceng C, Wang C, Zhan H, Ding X, Lipids Health Dis 2014 13 67
    • (2014) Lipids Health Dis , vol.13 , pp. 67
    • Huang, C.1    Ceng, C.2    Wang, C.3    Zhan, H.4    Ding, X.5
  • 21
    • 19044372537 scopus 로고    scopus 로고
    • Long-term inhibition of RhoA attenuates vascular contractility by enhancing endothelial NO production in an intact rabbit mesenteric artery
    • DOI 10.1161/01.RES.0000165483.34603.91
    • Long-term inhibition of RhoA attenuates vascular contractility by enhancing endothelial NO production in an intact rabbit mesenteric artery. Shiga N, Hirano K, Hirano M, Nishimura J, Nawata H, Kanaide H, Circ Res 2005 96 1014 1021 (Pubitemid 40712802)
    • (2005) Circulation Research , vol.96 , Issue.9 , pp. 1014-1021
    • Shiga, N.1    Hirano, K.2    Hirano, M.3    Nishimura, J.4    Nawata, H.5    Kanaide, H.6
  • 22
    • 84862776132 scopus 로고    scopus 로고
    • Metformin-based treatment for obesity-related hypertension: A randomized, double-blind, placebo-controlled trial
    • Metformin-based treatment for obesity-related hypertension: a randomized, double-blind, placebo-controlled trial. He H, Zhao Z, Chen J, Ni Y, Zhong J, Yan Z, Li Y, Liu D, Pletcher MJ, Zhu Z, J Hypertens 2012 30 1430 1439
    • (2012) J Hypertens , vol.30 , pp. 1430-1439
    • He, H.1    Zhao, Z.2    Chen, J.3    Ni, Y.4    Zhong, J.5    Yan, Z.6    Li, Y.7    Liu, D.8    Pletcher, M.J.9    Zhu, Z.10
  • 23
    • 24044543259 scopus 로고    scopus 로고
    • Metformin reduces C-reactive protein but not complement factor C3 in overweight patients with Type 2 diabetes mellitus
    • DOI 10.1111/j.1464-5491.2005.01632.x
    • Metformin reduces C-reactive protein but not complement factor C3 in overweight patients with Type 2 diabetes mellitus. Carter AM, Bennett CE, Bostock JA, Grant PJ, Diabet Med 2005 22 1282 1284 (Pubitemid 41224195)
    • (2005) Diabetic Medicine , vol.22 , Issue.9 , pp. 1282-1284
    • Carter, A.M.1    Bennett, C.E.2    Bostock, J.A.3    Grant, P.J.4
  • 25
    • 84900431784 scopus 로고    scopus 로고
    • Role of nitric oxide synthases in the pathogenesis of cardiovascular disease
    • Role of nitric oxide synthases in the pathogenesis of cardiovascular disease. Tsutsui M, Shimokawa H, Otsuji Y, Yanagihara N, Nihon Yakurigaku Zasshi 2014 143 226 231
    • (2014) Nihon Yakurigaku Zasshi , vol.143 , pp. 226-231
    • Tsutsui, M.1    Shimokawa, H.2    Otsuji, Y.3    Yanagihara, N.4
  • 26
    • 48349116165 scopus 로고    scopus 로고
    • Metformin: Effects on micro and macrovascular complications in type 2 diabetes
    • Metformin: effects on micro and macrovascular complications in type 2 diabetes. Bailey CJ, Cardiovasc Drugs Ther 2008 22 215 224
    • (2008) Cardiovasc Drugs Ther , vol.22 , pp. 215-224
    • Bailey, C.J.1
  • 27
    • 0036784012 scopus 로고    scopus 로고
    • Acute and chronic NOS inhibition enhances alpha(2)- adrenoreceptor- stimulated RhoA and Rho kinase in rat aorta
    • Acute and chronic NOS inhibition enhances alpha(2)- adrenoreceptor- stimulated RhoA and Rho kinase in rat aorta. Carter RW, Begaye M, Kanagy NL, Am J Physiol Heart Circ Physiol 2002 283 1361 H1369
    • (2002) Am J Physiol Heart Circ Physiol , vol.283
    • Carter, R.W.1    Begaye, M.2    Kanagy, N.L.3
  • 28
    • 18244401416 scopus 로고    scopus 로고
    • Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats
    • DOI 10.1161/hy0202.103271
    • Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats. Kataoka C, Egashira K, Inoue S, Takemoto M, Ni W, Koyanagi M, Kitamoto S, Usui M, Kaibuchi K, Shimokawa H, Takeshita A, Hypertension 2002 39 245 250 (Pubitemid 34165223)
    • (2002) Hypertension , vol.39 , Issue.2 I , pp. 245-250
    • Kataoka, C.1    Egashira, K.2    Inoue, S.3    Takemoto, M.4    Ni, W.5    Koyanagi, M.6    Kitamoto, S.7    Usui, M.8    Kaibuchi, K.9    Shimokawa, H.10    Takeshita, A.11
  • 29
    • 71549141594 scopus 로고    scopus 로고
    • Advanced glycation end products increase endothelial permeability through the RAGE/Rho signaling pathway
    • Advanced glycation end products increase endothelial permeability through the RAGE/Rho signaling pathway. Hirose A, Tanikawa T, Mori H, Okada Y, Tanaka Y, FEBS Lett 2010 584 61 66
    • (2010) FEBS Lett , vol.584 , pp. 61-66
    • Hirose, A.1    Tanikawa, T.2    Mori, H.3    Okada, Y.4    Tanaka, Y.5
  • 30
    • 84869232677 scopus 로고    scopus 로고
    • SDF-1alpha upregulation by atorvastatin in rats with acute myocardial infarction via nitric oxide production confers anti-inflammatory and anti-apoptotic effects
    • SDF-1alpha upregulation by atorvastatin in rats with acute myocardial infarction via nitric oxide production confers anti-inflammatory and anti-apoptotic effects. Qiu R, Cai A, Dong Y, Zhou Y, Yu D, Huang Y, Zheng D, Rao S, Feng Y, Mai W, J Biomed Sci 2012 19 99
    • (2012) J Biomed Sci , vol.19 , pp. 99
    • Qiu, R.1    Cai, A.2    Dong, Y.3    Zhou, Y.4    Yu, D.5    Huang, Y.6    Zheng, D.7    Rao, S.8    Feng, Y.9    Mai, W.10
  • 31
    • 33645299329 scopus 로고    scopus 로고
    • Anti-inflammatory drugs and their effects on type 2 diabetes
    • Anti-inflammatory drugs and their effects on type 2 diabetes. Deans KA, Sattar N, Diabetes Technol Ther 2006 8 18 27
    • (2006) Diabetes Technol Ther , vol.8 , pp. 18-27
    • Deans, K.A.1    Sattar, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.