2-Aminobenzoxazole ligands of the hepatitis C virus internal ribosome entry site

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 15, 2014, Pages 3521-3525

  Rynearson, Kevin D ^a,b   Charrette, Brian ^a   Gabriel, Christopher ^a,c   Moreno, Jesus ^a,d   Boerneke, Mark A ^a   Dibrov, Sergey M ^a   Hermann, Thomas ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antivirals; HCV; RNA target; Translation inhibitor

Indexed keywords

2 AMINOBENZOXAZOLE DERIVATIVE; BENZIMIDAZOLE DERIVATIVE; BENZOXAZOLE DERIVATIVE; LIGAND; RNA; UNCLASSIFIED DRUG; BENZIMIDAZOLE; ANTIVIRUS AGENT; VIRUS RNA;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEPATITIS C VIRUS; HYDROGEN BOND; INTERNAL RIBOSOME ENTRY SITE; LIGAND BINDING; NONHUMAN; STRUCTURE ACTIVITY RELATION; OBSERVATIONAL STUDY; VIRUS TRANSCRIPTION; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; HEPACIVIRUS; METABOLISM; RIBOSOME; SYNTHESIS;

HEPATITIS C VIRUS;

ANTIVIRAL AGENTS; BENZOXAZOLES; HEPACIVIRUS; LIGANDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; RIBOSOMES; RNA, VIRAL;

EID: 84904047420     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.05.088     Document Type: Article

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