Regioselective synthesis of cytarabine monopropionate by using a fungal whole-cell biocatalyst in nonaqueous medium

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 15, 2014, Pages 3377-3380

  Yang, Mei Yan ^a   Wu, Hui ^a   Lu, Zhi Hong ^a   Li, Xiao Feng ^a   Lai, Fu Rao ^a   Zhao, Guang Lei ^a  

^a SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Acylation; Fungal whole cell; Nucleoside; Regioselectivity; Solvent engineering

Indexed keywords

CYTARABINE DERIVATIVE; CYTARABINE MONOPROPIONATE; DIISOPROPYL ETHER; DIMETHYL SULFOXIDE; HEXANE; ORGANIC SOLVENT; PROPIONIC ACID DERIVATIVE; PYRIDINE; UNCLASSIFIED DRUG; VINYL PROPIONATE; CYTARABINE; VINYL DERIVATIVE; NUCLEOSIDE ANALOG;

ACYLATION; ARTICLE; ASPERGILLUS ORYZAE; BIOCATALYSIS; BIOCATALYST; CHEMICAL PARAMETERS; CULTURE MEDIUM; DRUG SYNTHESIS; FUNGAL CELL; HYDROPHOBICITY; NONHUMAN; REGIOSELECTIVE ACYLATION; REGIOSELECTIVITY; SHAKING SPEED; TEMPERATURE; THERMOSTABILITY; VELOCITY; WHOLE CELL; ANALOGS AND DERIVATIVES; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; METABOLISM; STEREOISOMERISM; WHOLE CELL BIOCATALYSIS;

ARA; ASPERGILLUS ORYZAE;

ASPERGILLUS ORYZAE; BIOCATALYSIS; CYTARABINE; MOLECULAR STRUCTURE; STEREOISOMERISM; VINYL COMPOUNDS;

EID: 84904045337     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.05.092     Document Type: Article

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