-
1
-
-
84887236077
-
Identification of domperidone metabolites in plasma and urine of gastroparesis patients with LC-ESI-MS/MS
-
Amir SY, Upendra AA, Murali P, et al. (2013). Identification of domperidone metabolites in plasma and urine of gastroparesis patients with LC-ESI-MS/MS. Xenobiotica 43: 1073-83.
-
(2013)
Xenobiotica
, vol.43
, pp. 1073-1083
-
-
Amir, S.Y.1
Upendra, A.A.2
Murali, P.3
-
2
-
-
27744581872
-
4 agonist therapy reduces response fluctuations in Parkinson's disease
-
DOI 10.1016/j.parkreldis.2005.06.007, PII S1353802005001343
-
Asai H, Udaka F, Hirano M, et al. (2005). Increased gastric motility during 5-HT4 agonist therapy reduces response fluctuations in Parkinson's disease. Parkinsonism Relat Disord 11: 499-502. (Pubitemid 41627841)
-
(2005)
Parkinsonism and Related Disorders
, vol.11
, Issue.8
, pp. 499-502
-
-
Asai, H.1
Udaka, F.2
Hirano, M.3
Minami, T.4
Oda, M.5
Kubori, T.6
Nishinaka, K.7
Kameyama, M.8
Ueno, S.9
-
3
-
-
84892847151
-
An analysis of the use of dogs in predicting human toxicology and dog safety
-
Bailey J, Thew M, Balls M. (2013). An analysis of the use of dogs in predicting human toxicology and dog safety. Altern Lab Anim 41: 335-50.
-
(2013)
Altern Lab Anim
, vol.41
, pp. 335-350
-
-
Bailey, J.1
Thew, M.2
Balls, M.3
-
5
-
-
43249127643
-
Mosapride in gastrointestinal disorders
-
Curran MP, Robinson DM. (2008). Mosapride in gastrointestinal disorders. Drugs 68: 981-91.
-
(2008)
Drugs
, vol.68
, pp. 981-991
-
-
Curran, M.P.1
Robinson, D.M.2
-
6
-
-
84903990478
-
Structural elucidation of in vitro and in vivo metabolites of cryptotanshinone by HPLC- DAD-ESI-MSn
-
Dai HX, Wang MM, Li XR, et al. (2008). Structural elucidation of in vitro and in vivo metabolites of cryptotanshinone by HPLC- DAD-ESI-MSn. J Pharm Biomed Anal 50: 27-34.
-
(2008)
J Pharm Biomed Anal
, vol.50
, pp. 27-34
-
-
Dai, H.X.1
Wang, M.M.2
Li, X.R.3
-
7
-
-
33745752978
-
Increasing speed and throughput when using HPLC-MS/MS systems for drug metabolism and pharmacokinetic screening
-
Hsieh Y, Korfmacher WA. (2006). Increasing speed and throughput when using HPLC-MS/MS systems for drug metabolism and pharmacokinetic screening. Curr Drug Metab 7: 479-89.
-
(2006)
Curr Drug Metab
, vol.7
, pp. 479-489
-
-
Hsieh, Y.1
Korfmacher, W.A.2
-
8
-
-
22844447147
-
Mosapride citrate, a novel 5-HT4 agonist and partial 5-HT3 antagonist, amerliorates constipation in Parkinsonian patients
-
DOI 10.1002/mds.20387
-
Liu Z, Sakakibara R, Odaka T, et al. (2005). Mosapride citrate, a novel 5-HT4 agonist and partial 5-HT3 antagonist, ameliorates constipation in parkinsonian patients. Mov Disord 20: 680-6. (Pubitemid 41051779)
-
(2005)
Movement Disorders
, vol.20
, Issue.6
, pp. 680-686
-
-
Liu, Z.1
Sakakibara, R.2
Odaka, T.3
Uchiyama, T.4
Yamamoto, T.5
Ito, T.6
Asahina, M.7
Yamaguchi, K.8
Yamaguchi, T.9
Hattori, T.10
-
9
-
-
0027385312
-
14C]mosapride citrate after repeated oral administration in rats
-
Matsumoto S, Tagawa M, Hatoyama T, et al. (1993a). Absorption, distribution, metabolism and excretion of [carbonyl-14C]mosapride citrate after repeated oral administration in rats. Arzneimittelforschung 43: 1103-8. (Pubitemid 23311889)
-
(1993)
Arzneimittel-Forschung/Drug Research
, vol.43
, Issue.10
, pp. 1103-1108
-
-
Matsumoto, S.1
Tagawa, M.2
Hatoyama, T.3
Fujii, T.4
Miyazaki, H.5
Sekine, Y.6
-
10
-
-
0027672410
-
14C]mosapride citrate after a single oral administration in rats, dogs and monkeys
-
Matsumoto S, Yoshida K, Itogawa A, et al. (1993b). Metabolism of [carbonyl-14C]mosapride citrate after a single oral administration in rats, dogs and monkeys. Arzneimittelforschung 43: 1095-102. (Pubitemid 23311888)
-
(1993)
Arzneimittel-Forschung/Drug Research
, vol.43
, Issue.10
, pp. 1095-1102
-
-
Matsumoto, S.1
Yoshida, K.2
Itogawa, A.3
Tagawa, M.4
Fujii, T.5
Miyazaki, H.6
Sekine, Y.7
-
11
-
-
30744449005
-
The impact of recent innovations in the use of liquid chromatography-mass spectrometry in support of drug metabolism studies: Are we all the way there yet?
-
Nassar AEF, Talaat RE, Kamel AM. (2006). The impact of recent innovations in the use of liquid chromatography-mass spectrometry in support of drug metabolism studies: are we all the way there yet? Curr Opin Drug Discov Devel 9: 61-74. (Pubitemid 43099076)
-
(2006)
Current Opinion in Drug Discovery and Development
, vol.9
, Issue.1
, pp. 61-74
-
-
Nassar, A.-E.F.1
Talaat, R.E.2
Kamel, A.M.3
-
12
-
-
0033832991
-
Liquid chromatography-mass spectrometry in the study of the metabolism of drugs and other xenobiotics
-
Oliveira EJ, Watson DG. (2000). Liquid chromatography-mass spectrometry in the study of the metabolism of drugs and other xenobiotics. Biomed Chromatogr 14: 351-72.
-
(2000)
Biomed Chromatogr
, vol.14
, pp. 351-372
-
-
Oliveira, E.J.1
Watson, D.G.2
-
13
-
-
34447293729
-
New perspectives in bio-analytical techniques for preclinical characterization of a drug candidate: UPLC-MS/MS in in vitro metabolism and pharmacokinetic studies
-
DOI 10.1016/j.jpba.2006.12.012, PII S0731708506008314
-
Pedraglio S, Rozio MG, Misiano P, et al. (2007). New perspectives in bio-analytical techniques for preclinical characterization of a drug candidate: UPLC-MS/MS in in vitro metabolism and pharmacokinetic studies. J Pharm Biomed Anal 44: 665-73. (Pubitemid 47039194)
-
(2007)
Journal of Pharmaceutical and Biomedical Analysis
, vol.44
, Issue.SPEC. ISS. 3
, pp. 665-673
-
-
Pedraglio, S.1
Rozio, M.G.2
Misiano, P.3
Reali, V.4
Dondio, G.5
Bigogno, C.6
-
14
-
-
0027320885
-
Pharmacokinetics of the gastrokinetic agent mosapride citrate after single and multiple oral administrations in healthy subjects
-
Sakashita M, Yamaguchi T, Miyazaki H, et al. (1993). Pharmacokinetics of the gastrokinetic agent mosapride citrate after single and multiple oral administrations in healthy subjects. Arzneimittelforschung 43: 867-72. (Pubitemid 23254936)
-
(1993)
Arzneimittel-Forschung/Drug Research
, vol.43
, Issue.8
, pp. 867-872
-
-
Sakashita, M.1
Yamaguchi, T.2
Miyazaki, H.3
Sekine, Y.4
Nomiyama, T.5
Tanaka, S.6
Miwa, T.7
Harasawa, S.8
-
15
-
-
67349107106
-
Characterization of metabolic profile of mosapride citrate in rat and identification of two new metabolites: Mosapride N-oxide and morpholine ringopened mosapride by UPLC-ESI-MS/MS
-
Sun XH, Niu LL, Li XQ, et al. (2009a). Characterization of metabolic profile of mosapride citrate in rat and identification of two new metabolites: Mosapride N-oxide and morpholine ringopened mosapride by UPLC-ESI-MS/MS. J Pharm Biomed Anal 50: 27-34.
-
(2009)
J Pharm Biomed Anal
, vol.50
, pp. 27-34
-
-
Sun, X.H.1
Niu, L.L.2
Li, X.Q.3
-
16
-
-
64649097518
-
Fungal biotransformation of mosapride by Cunninghamella elegans
-
Sun XH, Man F, Pang LY, et al. (2009b). Fungal biotransformation of mosapride by Cunninghamella elegans. J Mol Catal B: Enzym 59: 82-9.
-
(2009)
J Mol Catal B: Enzym
, vol.59
, pp. 82-89
-
-
Sun, X.H.1
Man, F.2
Pang, L.Y.3
-
17
-
-
53549097600
-
-
U.S. Food and Drug Administration, Center for Drug Evaluation and Research (CDER), [last accessed February 2008]
-
U.S. Food and Drug Administration. (2008). Guidance for industry safety testing of drug metabolites. U.S. Food and Drug Administration, Center for Drug Evaluation and Research (CDER). Available from: http://www.fda.gov/downloads/ drugs/guidancecomplianceregulatoryi nformation/guidances/ucm079266.pdf [last accessed February 2008].
-
(2008)
Guidance for Industry Safety Testing of Drug Metabolites
-
-
-
18
-
-
0032984510
-
Pharmacological effects of the gastroprokinetic agent mosapride citrate
-
Yoshida N. (1999). Pharmacological effects of the gastroprokinetic agent mosapride citrate. Nippon Yakurigaku Zasshi 113: 299-307. (Pubitemid 29254500)
-
(1999)
Folia Pharmacologica Japonica
, vol.113
, Issue.5
, pp. 299-307
-
-
Yoshida, N.1
|