Characterization of metabolic profile of mosapride citrate in rat and identification of two new metabolites: Mosapride N-oxide and morpholine ring-opened mosapride by UPLC-ESI-MS/MS

Journal of Pharmaceutical and Biomedical Analysis

Volumn 50, Issue 1, 2009, Pages 27-34

  Sun, Xiaohong ^a   Niu, Lili ^a   Li, Xiaoqin ^a   Lu, Xiumei ^a   Li, Famei ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Metabolism; Morpholine ring opened mosapride; Mosapride; Mosapride N oxide; UPLC ESI MS MS

Indexed keywords

MORPHOLINE; MOSAPRIDE CITRATE;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL STRUCTURE; DEALKYLATION; EXPERIMENTAL RAT; GLUCURONIDATION; HYDROXYLATION; ION PAIR CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MALE; MAMMAL; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY;

ANIMALS; BENZAMIDES; BILE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FECES; GASTROINTESTINAL AGENTS; MALE; MORPHOLINES; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 67349107106     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.03.011     Document Type: Article

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