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Volumn 25, Issue 5, 2014, Pages 328-336

Variability of on-treatment platelet reactivity in patients on clopidogrel

Author keywords

Acute coronary syndromes; Clopidogrel; Coronary artery disease; On treatment platelet reactivity; Vasodilator stimulated phosphoprotein phosphorylation assay

Indexed keywords

ACETYLSALICYLIC ACID; CHOLESTEROL; CLOPIDOGREL; FIBRINOGEN RECEPTOR ANTAGONIST; GLUCOSE; HIGH DENSITY LIPOPROTEIN; SIMVASTATIN; ANTITHROMBOCYTIC AGENT; TICLOPIDINE;

EID: 84904002295     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.3109/09537104.2013.827781     Document Type: Article
Times cited : (17)

References (55)
  • 1
    • 0036379817 scopus 로고    scopus 로고
    • Individual variations of platelet inhibition after loading doses of clopidogrel
    • Jaremo P, Lindahl TL, Fransson SG, Richter A. Individual variations of platelet inhibition after loading doses of clopidogrel. J Intern Med 2002;252: 233-238.
    • (2002) J Intern Med , vol.252 , pp. 233-238
    • Jaremo, P.1    Lindahl, T.L.2    Fransson, S.G.3    Richter, A.4
  • 2
    • 0038649988 scopus 로고    scopus 로고
    • Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity
    • DOI 10.1161/01.CIR.0000072771.11429.83
    • Gurbel PA, Bliden KP, Hiatt BL, O'Connor CM. Clopidogrel for coronary stenting: Response variability, drug resistance, and the effect of pretreatment platelet reactivity. Circulation 2003;107: 2908-2913. (Pubitemid 36736631)
    • (2003) Circulation , vol.107 , Issue.23 , pp. 2908-2913
    • Gurbel, P.A.1    Bliden, K.P.2    Hiatt, B.L.3    O'Connor, C.M.4
  • 4
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • DOI 10.1056/NEJMoa010746
    • Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001;345: 494-502. (Pubitemid 32758501)
    • (2001) New England Journal of Medicine , vol.345 , Issue.7 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3    Chrolavicius, S.4    Tognoni, G.5    Fox, K.K.6
  • 5
    • 27644548513 scopus 로고    scopus 로고
    • Addition of clopidogrel to aspirin in 45, 852 patients with acute myocardial infarction: Randomised placebo-controlled trial
    • Chen ZM, Jiang LX, Chen YP, Xie JX, Pan HC, Peto R, Collins R, Liu LS. Addition of clopidogrel to aspirin in 45, 852 patients with acute myocardial infarction: Randomised placebo-controlled trial. Lancet 2005;366: 1607-1621.
    • (2005) Lancet , vol.366 , pp. 1607-1621
    • Chen, Z.M.1    Jiang, L.X.2    Chen, Y.P.3    Xie, J.X.4    Pan, H.C.5    Peto, R.6    Collins, R.7    Liu, L.S.8
  • 6
    • 34447636769 scopus 로고    scopus 로고
    • Vasodilator-stimulated phosphoprotein phosphorylation analysis prior to percutaneous coronary intervention for exclusion of postprocedural major adverse cardiovascular events
    • DOI 10.1111/j.1538-7836.2007.02609.x
    • Bonello L, Paganelli F, Arpin-Bornet M, Auquier P, Sampol J, Dignat-George F, Barragan P, Camoin-Jau L. Vasodilator-stimulated phosphoprotein phosphorylation analysis prior to percutaneous coronary intervention for exclusion of postprocedural major adverse cardiovascular events. J Thromb Haemost 2007;5: 1630-1636. (Pubitemid 47091403)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.8 , pp. 1630-1636
    • Bonello, L.1    Paganelli, F.2    Arpin-Bornet, M.3    Auquier, P.4    Sampol, J.5    Dignat-George, F.6    Barragan, P.7    Camoin-Jau, L.8
  • 7
    • 59849120163 scopus 로고    scopus 로고
    • Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-of-care assay: A 12- month follow-up
    • Marcucci R, Gori AM, Paniccia R, Giusti B, Valente S, Giglioli C, Buonamici P, Antoniucci D, Abbate R, Gensini GF. Cardiovascular death and nonfatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting are predicted by residual platelet reactivity to ADP detected by a point-of-care assay: A 12- month follow-up. Circulation 2009;119: 237-242.
    • (2009) Circulation , vol.119 , pp. 237-242
    • Marcucci, R.1    Gori, A.M.2    Paniccia, R.3    Giusti, B.4    Valente, S.5    Giglioli, C.6    Buonamici, P.7    Antoniucci, D.8    Abbate, R.9    Gensini, G.F.10
  • 11
    • 41249093357 scopus 로고    scopus 로고
    • Adjusted Clopidogrel Loading Doses According to Vasodilator-Stimulated Phosphoprotein Phosphorylation Index Decrease Rate of Major Adverse Cardiovascular Events in Patients With Clopidogrel Resistance. A Multicenter Randomized Prospective Study
    • DOI 10.1016/j.jacc.2007.12.044, PII S0735109708005664
    • Bonello L, Camoin-Jau L, Arques S, Boyer C, Panagides D, Wittenberg O, Simeoni MC, Barragan P, Dignat-George F, Paganelli F. Adjusted clopidogrel loading doses according to vasodilatorstimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance: A multicenter randomized prospective study. J Am Coll Cardiol 2008;51: 1404-1411. (Pubitemid 351447314)
    • (2008) Journal of the American College of Cardiology , vol.51 , Issue.14 , pp. 1404-1411
    • Bonello, L.1    Camoin-Jau, L.2    Arques, S.3    Boyer, C.4    Panagides, D.5    Wittenberg, O.6    Simeoni, M.-C.7    Barragan, P.8    Dignat-George, F.9    Paganelli, F.10
  • 12
    • 84861857758 scopus 로고    scopus 로고
    • A randomized trial of prasugrel versus clopidogrel in patients with high platelet reactivity on clopidogrel after elective percutaneous coronary intervention with implantation of drug-eluting stents: Results of the TRIGGERPCI (testing platelet reactivity in patients undergoing elective stent placement on clopidogrel to guide alternative therapy with prasugrel) study
    • Trenk D, Stone GW, Gawaz M, Kastrati A, Angiolillo DJ, Muller U, Richardt G, Jakubowski JA, Neumann FJ. A randomized trial of prasugrel versus clopidogrel in patients with high platelet reactivity on clopidogrel after elective percutaneous coronary intervention with implantation of drug-eluting stents: Results of the TRIGGERPCI (testing platelet reactivity in patients undergoing elective stent placement on clopidogrel to guide alternative therapy with prasugrel) study. J Am Coll Cardiol 2012;59: 2159-2164.
    • (2012) J Am Coll Cardiol , vol.59 , pp. 2159-2164
    • Trenk, D.1    Stone, G.W.2    Gawaz, M.3    Kastrati, A.4    Angiolillo, D.J.5    Muller, U.6    Richardt, G.7    Jakubowski, J.A.8    Neumann, F.J.9
  • 16
    • 84870047461 scopus 로고    scopus 로고
    • Interindividual variability in the efficacy of oral antiplatelet drugs: Definitions, mechanisms and clinical importance
    • Wurtz M, Grove EL. Interindividual variability in the efficacy of oral antiplatelet drugs: Definitions, mechanisms and clinical importance. Curr Pharm Des 2012;18: 5344-5361.
    • (2012) Curr Pharm des , vol.18 , pp. 5344-5361
    • Wurtz, M.1    Grove, E.L.2
  • 17
    • 77951712355 scopus 로고    scopus 로고
    • Long-term aspirin and clopidogrel response evaluated by light transmission aggregometry, Verify Now, and thrombelastography in patients undergoing percutaneous coronary intervention
    • Madsen EH, Saw J, Kristensen SR, Schmidt EB, Pittendreigh C, Maurer-Spurej E. Long-term aspirin and clopidogrel response evaluated by light transmission aggregometry, Verify Now, and thrombelastography in patients undergoing percutaneous coronary intervention. Clin Chem 2010;56: 839-847.
    • (2010) Clin Chem , vol.56 , pp. 839-847
    • Madsen, E.H.1    Saw, J.2    Kristensen, S.R.3    Schmidt, E.B.4    Pittendreigh, C.5    Maurer-Spurej, E.6
  • 18
    • 56349140778 scopus 로고    scopus 로고
    • The ELAPSE (Evaluation of Long-Term Clopidogrel Antiplatelet and Systemic Anti-Inflammatory Effects) study
    • Saw J, Madsen EH, Chan S, Maurer-Spurej E. The ELAPSE (Evaluation of Long-Term Clopidogrel Antiplatelet and Systemic Anti-Inflammatory Effects) study. J Am Coll Cardiol 2008;52: 1826-1833.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1826-1833
    • Saw, J.1    Madsen, E.H.2    Chan, S.3    Maurer-Spurej, E.4
  • 20
    • 84877728751 scopus 로고    scopus 로고
    • High-Dose atorvastatin on the pharmacodynamic effects of double-dose clopidogrel in patients undergoing percutaneous coronary interventions: The ACHIDO (Atorvastatin and Clopidogrel HIgh DOse in stable patients with residual high platelet activity) Study
    • Leoncini M, Toso A, Maioli M, Angiolillo DJ, Giusti B, Marcucci R, Abbate R, Bellandi F. High-Dose atorvastatin on the pharmacodynamic effects of double-dose clopidogrel in patients undergoing percutaneous coronary interventions: The ACHIDO (Atorvastatin and Clopidogrel HIgh DOse in stable patients with residual high platelet activity) Study. JACC Cardiovasc Interv 2013;6: 169-179.
    • (2013) JACC Cardiovasc Interv , vol.6 , pp. 169-179
    • Leoncini, M.1    Toso, A.2    Maioli, M.3    Angiolillo, D.J.4    Giusti, B.5    Marcucci, R.6    Abbate, R.7    Bellandi, F.8
  • 21
    • 64549133799 scopus 로고    scopus 로고
    • Evaluation of individualized clopidogrel therapy after drug-eluting stent implantation in patients with high residual platelet reactivity: Design and rationale of the GRAVITAS trial
    • 24 e1
    • Price MJ, Berger PB, Angiolillo DJ, Teirstein PS, Tanguay JF, Kandzari DE, Cannon CP, Topol EJ. Evaluation of individualized clopidogrel therapy after drug-eluting stent implantation in patients with high residual platelet reactivity: Design and rationale of the GRAVITAS trial. Am Heart J 2009;157:818-824, 24 e1.
    • (2009) Am Heart J , vol.157 , pp. 818-824
    • Price, M.J.1    Berger, P.B.2    Angiolillo, D.J.3    Teirstein, P.S.4    Tanguay, J.F.5    Kandzari, D.E.6    Cannon, C.P.7    Topol, E.J.8
  • 22
    • 38049169354 scopus 로고    scopus 로고
    • 2007 Focused Update of the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: 2007 Writing Group to Review New Evidence and Update the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention, Writing on Behalf of the 2005 Writing Committee
    • King 3rd SB, Smith Jr SC, Hirshfeld Jr JW, Jacobs AK, Morrison DA, Williams DO, Feldman TE, Kern MJ, O'Neill WW, Schaff HV, et al. 2007 Focused Update of the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: 2007 Writing Group to Review New Evidence and Update the ACC/AHA/SCAI 2005 Guideline Update for Percutaneous Coronary Intervention, Writing on Behalf of the 2005 Writing Committee. Circulation 2008;117: 261-295.
    • (2008) Circulation , vol.117 , pp. 261-295
    • King III, S.B.1    Smith Jr., S.C.2    Hirshfeld Jr., J.W.3    Jacobs, A.K.4    Morrison, D.A.5    Williams, D.O.6    Feldman, T.E.7    Kern, M.J.8    O'Neill, W.W.9    Schaff, H.V.10
  • 23
    • 77958128969 scopus 로고    scopus 로고
    • Guidelines on myocardial revascularization: The task force on myocardial revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)
    • Wijns W, Kolh P, Danchin N, Di Mario C, Falk V, Folliguet T, Garg S, Huber K, James S, Knuuti J, et al. Guidelines on myocardial revascularization: The task force on myocardial revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J 2010;31: 2501-2555.
    • (2010) Eur Heart J , vol.31 , pp. 2501-2555
    • Wijns, W.1    Kolh, P.2    Danchin, N.3    Di Mario, C.4    Falk, V.5    Folliguet, T.6    Garg, S.7    Huber, K.8    James, S.9    Knuuti, J.10
  • 24
    • 84857749223 scopus 로고    scopus 로고
    • Vasodilator-stimulated phosphoprotein-phosphorylation assay in patients on clopidogrel: Does standardisation matter?
    • Freynhofer MK, Bruno V, Willheim M, Hubl W, Wojta J, Huber K. Vasodilator-stimulated phosphoprotein-phosphorylation assay in patients on clopidogrel: Does standardisation matter? Thromb Haemost 2012;107: 538-544.
    • (2012) Thromb Haemost , vol.107 , pp. 538-544
    • Freynhofer, M.K.1    Bruno, V.2    Willheim, M.3    Hubl, W.4    Wojta, J.5    Huber, K.6
  • 25
    • 79958110089 scopus 로고    scopus 로고
    • Prospective evaluation of on-clopidogrel platelet reactivity over time in patients treated with percutaneous coronary intervention relationship with gene polymorphisms and clinical outcome
    • Campo G, Parrinello G, Ferraresi P, Lunghi B, Tebaldi M, Miccoli M, Marchesini J, Bernardi F, Ferrari R, Valgimigli M. Prospective evaluation of on-clopidogrel platelet reactivity over time in patients treated with percutaneous coronary intervention relationship with gene polymorphisms and clinical outcome. J Am Coll Cardiol 2011; 57: 2474-2483.
    • (2011) J Am Coll Cardiol , vol.57 , pp. 2474-2483
    • Campo, G.1    Parrinello, G.2    Ferraresi, P.3    Lunghi, B.4    Tebaldi, M.5    Miccoli, M.6    Marchesini, J.7    Bernardi, F.8    Ferrari, R.9    Valgimigli, M.10
  • 26
    • 0037326063 scopus 로고    scopus 로고
    • Onset and extent of platelet inhibition by clopidogrel loading in patients undergoing elective coronary stenting: The Plavix Reduction Of New Thrombus Occurrence (PRONTO) trial
    • DOI 10.1067/mhj.2003.109
    • Gurbel PA, Cummings CC, Bell CR, Alford AB, Meister AF, Serebruany VL. Onset and extent of platelet inhibition by clopidogrel loading in patients undergoing elective coronary stenting: The Plavix Reduction Of New Thrombus Occurrence (PRONTO) trial. Am Heart J 2003;145: 239-247. (Pubitemid 36207944)
    • (2003) American Heart Journal , vol.145 , Issue.2 , pp. 239-247
    • Gurbel, P.A.1    Cummings, C.C.2    Bell, C.R.3    Alford, A.B.4    Meister, A.F.5    Serebruany, V.L.6
  • 27
    • 0029814641 scopus 로고    scopus 로고
    • Platelet activation and coronary stent implantation: Effect of antithrombotic therapy
    • Gawaz M, Neumann FJ, Ott I, May A, Schomig A. Platelet activation and coronary stent implantation. Effect of antithrombotic therapy. Circulation 1996;94: 279-285. (Pubitemid 26266110)
    • (1996) Circulation , vol.94 , Issue.3 , pp. 279-285
    • Gawaz, M.1    Neumann, F.-J.2    Ott, I.3    May, A.4    Schomig, A.5
  • 28
    • 77949568294 scopus 로고    scopus 로고
    • A randomised study comparing the antiplatelet and antiinflammatory effect of clopidogrel 150 mg/day versus 75 mg/day in patients with ST-segment elevation acute myocardial infarction and poor responsiveness to clopidogrel: Results from the DOUBLE study
    • Palmerini T, Barozzi C, Tomasi L, Sangiorgi D, Marzocchi A, De Servi S, Ortolani P, Reggiani LB, Alessi L, Lauria G, et al. A randomised study comparing the antiplatelet and antiinflammatory effect of clopidogrel 150 mg/day versus 75 mg/day in patients with ST-segment elevation acute myocardial infarction and poor responsiveness to clopidogrel: Results from the DOUBLE study. Thromb Res 2010;125: 309-314.
    • (2010) Thromb Res , vol.125 , pp. 309-314
    • Palmerini, T.1    Barozzi, C.2    Tomasi, L.3    Sangiorgi, D.4    Marzocchi, A.5    De Servi, S.6    Ortolani, P.7    Reggiani, L.B.8    Alessi, L.9    Lauria, G.10
  • 29
    • 77951667161 scopus 로고    scopus 로고
    • Sustained enhancement of residual platelet reactivity after coronary stenting in patients with myocardial infarction compared to elective patients
    • Althoff TF, Fischer M, Langer E, Ziemer S, Baumann G. Sustained enhancement of residual platelet reactivity after coronary stenting in patients with myocardial infarction compared to elective patients. Thromb Res 2010;125:e190-e196.
    • (2010) Thromb Res , vol.125
    • Althoff, T.F.1    Fischer, M.2    Langer, E.3    Ziemer, S.4    Baumann, G.5
  • 30
    • 85067776036 scopus 로고    scopus 로고
    • Increased platelet aggregation and turnover in the acute phase of STelevation myocardial infarction
    • Dec 5 [epub ahead of print]
    • Funck-Jensen KL, Dalsgaard J, Grove EL, Hvas AM, Kristensen SD. Increased platelet aggregation and turnover in the acute phase of STelevation myocardial infarction. Platelets 2012; Dec 5 [epub ahead of print].
    • (2012) Platelets
    • Funck-Jensen, K.L.1    Dalsgaard, J.2    Grove, E.L.3    Hvas, A.M.4    Kristensen, S.D.5
  • 31
    • 49349102948 scopus 로고    scopus 로고
    • Role of reticulated platelets and platelet size heterogeneity on platelet activity after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease
    • Guthikonda S, Alviar CL, Vaduganathan M, Arikan M, Tellez A, De Lao T, Granada JF, Dong JF, Kleiman NS, Lev EI. Role of reticulated platelets and platelet size heterogeneity on platelet activity after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease. J Am Coll Cardiol 2008; 52: 743-749.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 743-749
    • Guthikonda, S.1    Alviar, C.L.2    Vaduganathan, M.3    Arikan, M.4    Tellez, A.5    De Lao, T.6    Granada, J.F.7    Dong, J.F.8    Kleiman, N.S.9    Lev, E.I.10
  • 32
    • 79960034076 scopus 로고    scopus 로고
    • Is increased platelet turnover responsible for low responsiveness to different thienopyridienes? A case report of recurrent stent thromboses
    • Freynhofer MK, Bruno V, Brozovic I, Grove EL, Kristensen SD, Willheim M, Hubl W, Huber K. Is increased platelet turnover responsible for low responsiveness to different thienopyridienes? A case report of recurrent stent thromboses. Thromb Haemost 2011; 106: 182-184.
    • (2011) Thromb Haemost , vol.106 , pp. 182-184
    • Freynhofer, M.K.1    Bruno, V.2    Brozovic, I.3    Grove, E.L.4    Kristensen, S.D.5    Willheim, M.6    Hubl, W.7    Huber, K.8
  • 35
    • 38349168418 scopus 로고    scopus 로고
    • A comparison of the antiplatelet effects of prasugrel and high-dose clopidogrel as assessed by VASP-phosphorylation and light transmission aggregometry
    • Jakubowski JA, Payne CD, Li YG, Farid NA, Brandt JT, Small DS, Salazar DE, Winters KJ. A comparison of the antiplatelet effects of prasugrel and high-dose clopidogrel as assessed by VASP-phosphorylation and light transmission aggregometry. Thromb Haemost 2008;99: 215-222.
    • (2008) Thromb Haemost , vol.99 , pp. 215-222
    • Jakubowski, J.A.1    Payne, C.D.2    Li, Y.G.3    Farid, N.A.4    Brandt, J.T.5    Small, D.S.6    Salazar, D.E.7    Winters, K.J.8
  • 37
    • 84868332790 scopus 로고    scopus 로고
    • Platelet function during extended prasugrel and clopidogrel therapy for patients with ACS treated without revascularization: The TRILOGY ACS platelet function substudy
    • doi: 10.1001/jama.2012.17312
    • Gurbel PA, Erlinge D, Ohman EM, Neely B, Neely M, Goodman SG, Huber K, Chan MY, Cornel JH, Brown E, et al. Platelet Function During Extended Prasugrel and Clopidogrel Therapy for Patients With ACS Treated Without Revascularization: The TRILOGY ACS Platelet Function Substudy. JAMA 2012;308: 1785-94. doi: 10.1001/jama.2012.17312.
    • (2012) JAMA , vol.308 , pp. 1785-1794
    • Gurbel, P.A.1    Erlinge, D.2    Ohman, E.M.3    Neely, B.4    Neely, M.5    Goodman, S.G.6    Huber, K.7    Chan, M.Y.8    Cornel, J.H.9    Brown, E.10
  • 38
    • 54349121974 scopus 로고    scopus 로고
    • Calcium-channel blockers reduce the antiplatelet effect of clopidogrel
    • Siller-Matula JM, Lang I, Christ G, Jilma B. Calcium-channel blockers reduce the antiplatelet effect of clopidogrel. J Am Coll Cardiol 2008;52: 1557-1563.
    • (2008) J Am Coll Cardiol , vol.52 , pp. 1557-1563
    • Siller-Matula, J.M.1    Lang, I.2    Christ, G.3    Jilma, B.4
  • 39
    • 79952444959 scopus 로고    scopus 로고
    • Lack of impact of calciumchannel blockers on the pharmacodynamic effect and the clinical efficacy of clopidogrel after drug-eluting stenting
    • Sarafoff N, Neumann L, Morath T, Bernlochner I, Mehilli J, Schomig A, Kastrati A, Sibbing D. Lack of impact of calciumchannel blockers on the pharmacodynamic effect and the clinical efficacy of clopidogrel after drug-eluting stenting. Am Heart J 2011; 161: 605-610.
    • (2011) Am Heart J , vol.161 , pp. 605-610
    • Sarafoff, N.1    Neumann, L.2    Morath, T.3    Bernlochner, I.4    Mehilli, J.5    Schomig, A.6    Kastrati, A.7    Sibbing, D.8
  • 42
    • 71949115114 scopus 로고    scopus 로고
    • Relation of body mass index to high on-treatment platelet reactivity and of failed clopidogrel dose adjustment according to platelet reactivity monitoring in patients undergoing percutaneous coronary intervention
    • Bonello-Palot N, Armero S, Paganelli F, Mancini J, De Labriolle A, Bonello C, Levy N, Maillard L, Barragan P, Dignat-George F, et al. Relation of body mass index to high on-treatment platelet reactivity and of failed clopidogrel dose adjustment according to platelet reactivity monitoring in patients undergoing percutaneous coronary intervention. Am J Cardiol 2009;104: 1511-1515.
    • (2009) Am J Cardiol , vol.104 , pp. 1511-1515
    • Bonello-Palot, N.1    Armero, S.2    Paganelli, F.3    Mancini, J.4    De Labriolle, A.5    Bonello, C.6    Levy, N.7    Maillard, L.8    Barragan, P.9    Dignat-George, F.10
  • 43
    • 54949155995 scopus 로고    scopus 로고
    • ADP-induced platelet aggregation frequently fails to detect impaired clopidogrel-responsiveness in patients with coronary artery disease compared to a P2Y12-specific assay
    • Schafer A, Weinberger S, Flierl U, Eigenthaler M, Stork S, Walter U, Ertl G, Bauersachs J. ADP-induced platelet aggregation frequently fails to detect impaired clopidogrel-responsiveness in patients with coronary artery disease compared to a P2Y12-specific assay. Thromb Haemost 2008;100: 618-625.
    • (2008) Thromb Haemost , vol.100 , pp. 618-625
    • Schafer, A.1    Weinberger, S.2    Flierl, U.3    Eigenthaler, M.4    Stork, S.5    Walter, U.6    Ertl, G.7    Bauersachs, J.8
  • 44
    • 79960101367 scopus 로고    scopus 로고
    • Early determination of clopidogrel responsiveness by platelet reactivity indexidentifies patients at risk for cardiovascular events after myocardial infarction
    • Schafer A, Flierl U, Kossler J, Seydelmann N, Kobsar A, Stork S, Bauersachs J. Early determination of clopidogrel responsiveness by platelet reactivity indexidentifies patients at risk for cardiovascular events after myocardial infarction. Thromb Haemost 2011;106: 141-148.
    • (2011) Thromb Haemost , vol.106 , pp. 141-148
    • Schafer, A.1    Flierl, U.2    Kossler, J.3    Seydelmann, N.4    Kobsar, A.5    Stork, S.6    Bauersachs, J.7
  • 46
  • 47
    • 0028173543 scopus 로고
    • Inhibitory effect of high-density lipoprotein on platelet function is mediated by increase in nitric oxide synthase activity in platelets
    • Chen LY, Mehta JL. Inhibitory effect of high-density lipoprotein on platelet function is mediated by increase in nitric oxide synthase activity in platelets. Life Sci 1994;55: 1815-1821.
    • (1994) Life Sci , vol.55 , pp. 1815-1821
    • Chen, L.Y.1    Mehta, J.L.2
  • 49
    • 84863208556 scopus 로고    scopus 로고
    • Antiplatelet drug response status does not predict recurrent ischemic events in stable cardiovascular patients: Results of the Antiplatelet Drug Resistances and Ischemic Events study
    • Reny JL, Berdague P, Poncet A, Barazer I, Nolli S, Fabbro-Peray P, Schved JF, Bounameaux H, Mach F, de Moerloose P, et al. Antiplatelet drug response status does not predict recurrent ischemic events in stable cardiovascular patients: Results of the Antiplatelet Drug Resistances and Ischemic Events study. Circulation 2012;125: 3201-3210.
    • (2012) Circulation , vol.125 , pp. 3201-3210
    • Reny, J.L.1    Berdague, P.2    Poncet, A.3    Barazer, I.4    Nolli, S.5    Fabbro-Peray, P.6    Schved, J.F.7    Bounameaux, H.8    Mach, F.9    De Moerloose, P.10
  • 50
    • 78651090279 scopus 로고    scopus 로고
    • Platelet reactivity over time: Solid as a rock or not durable?
    • van Werkum JW, Ten Berg JM. Platelet reactivity over time: Solid as a rock or not durable? Thromb Haemost 2011;105: 3-4.
    • (2011) Thromb Haemost , vol.105 , pp. 3-4
    • Van Werkum, J.W.1    Ten Berg, J.M.2
  • 51
    • 0037406216 scopus 로고    scopus 로고
    • Durability of platelet inhibition by clopidogrel
    • DOI 10.1016/S0002-9149(03)00163-2
    • Gurbel PA, Bliden KP. Durability of platelet inhibition by clopidogrel. Am J Cardiol 2003;91: 1123-1125. (Pubitemid 36514934)
    • (2003) American Journal of Cardiology , vol.91 , Issue.9 , pp. 1123-1125
    • Gurbel, P.A.1    Bliden, K.P.2
  • 52
    • 79961046361 scopus 로고    scopus 로고
    • Multiple electrode aggregometry and vasodilator stimulated phosphoprotein-phosphorylation assay in clinical routine for prediction of postprocedural major adverse cardiovascular events
    • Freynhofer MK, Brozovic I, Bruno V, Farhan S, Vogel B, Jakl G, Willheim M, Hubl W, Wojta J, Huber K. Multiple electrode aggregometry and vasodilator stimulated phosphoprotein-phosphorylation assay in clinical routine for prediction of postprocedural major adverse cardiovascular events. Thromb Haemost 2011;106: 230-239.
    • (2011) Thromb Haemost , vol.106 , pp. 230-239
    • Freynhofer, M.K.1    Brozovic, I.2    Bruno, V.3    Farhan, S.4    Vogel, B.5    Jakl, G.6    Willheim, M.7    Hubl, W.8    Wojta, J.9    Huber, K.10
  • 53
    • 77953159705 scopus 로고    scopus 로고
    • Relationship between degree of P2Y12 receptor blockade and inhibition of P2Y12-mediated platelet function
    • Judge HM, Buckland RJ, Sugidachi A, Jakubowski JA, Storey RF. Relationship between degree of P2Y12 receptor blockade and inhibition of P2Y12-mediated platelet function. Thromb Haemost 2010;103: 1210-1217.
    • (2010) Thromb Haemost , vol.103 , pp. 1210-1217
    • Judge, H.M.1    Buckland, R.J.2    Sugidachi, A.3    Jakubowski, J.A.4    Storey, R.F.5
  • 55
    • 77956654443 scopus 로고    scopus 로고
    • Differential sensitivity and kinetics of response of different ex vivo tests monitoring functional variability of platelet response to clopidogrel
    • Bal Dit Sollier C, Berge N, Boval B, Dubar M, Drouet L. Differential sensitivity and kinetics of response of different ex vivo tests monitoring functional variability of platelet response to clopidogrel. Thromb Haemost 2010;104: 571-581.
    • (2010) Thromb Haemost , vol.104 , pp. 571-581
    • Bal Dit Sollier, C.1    Berge, N.2    Boval, B.3    Dubar, M.4    Drouet, L.5


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