-
1
-
-
81155123190
-
RIBBON-2: a randomized, double-blind, placebo-controlled, phase III trial evaluating the efficacy and safety of bevacizumab in combination with chemotherapy for second-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer
-
Brufsky AM, Hurvitz S, Perez E, Swamy R, Valero V, O'Neill V, Rugo HS: RIBBON-2: a randomized, double-blind, placebo-controlled, phase III trial evaluating the efficacy and safety of bevacizumab in combination with chemotherapy for second-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer. J Clin Oncol 2011, 29(32): 4286-4293.
-
(2011)
J Clin Oncol
, vol.29
, Issue.32
, pp. 4286-4293
-
-
Brufsky, A.M.1
Hurvitz, S.2
Perez, E.3
Swamy, R.4
Valero, V.5
O'Neill, V.6
Rugo, H.S.7
-
2
-
-
79952083872
-
Congestive heart failure risk in patients with breast cancer treated with bevacizumab
-
Choueiri TK, Mayer EL, Je Y, Rosenberg JE, Nguyen PL, Azzi GR, Bellmunt J, Burstein HJ, Schutz FA: Congestive heart failure risk in patients with breast cancer treated with bevacizumab. J Clin Oncol 2011, 29(6): 632-638.
-
(2011)
J Clin Oncol
, vol.29
, Issue.6
, pp. 632-638
-
-
Choueiri, T.K.1
Mayer, E.L.2
Je, Y.3
Rosenberg, J.E.4
Nguyen, P.L.5
Azzi, G.R.6
Bellmunt, J.7
Burstein, H.J.8
Schutz, F.A.9
-
3
-
-
0037687355
-
Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741
-
Citron ML, Berry DA, Cirrincione C, Hudis C, Winer EP, Gradishar WJ, Davidson NE, Martino S, Livingston R, Ingle JN, Perez EA, Carpenter J, Hurd D, Holland JF, Smith BL, Sartor CI, Leung EH, Abrams J, Schilsky RL, Muss HB, Norton L: Randomized trial of dose-dense versus conventionally scheduled and sequential versus concurrent combination chemotherapy as postoperative adjuvant treatment of node-positive primary breast cancer: first report of Intergroup Trial C9741/Cancer and Leukemia Group B Trial 9741. J Clin Oncol 2003, 21(8): 1431-1439.
-
(2003)
J Clin Oncol
, vol.21
, Issue.8
, pp. 1431-1439
-
-
Citron, M.L.1
Berry, D.A.2
Cirrincione, C.3
Hudis, C.4
Winer, E.P.5
Gradishar, W.J.6
Davidson, N.E.7
Martino, S.8
Livingston, R.9
Ingle, J.N.10
Perez, E.A.11
Carpenter, J.12
Hurd, D.13
Holland, J.F.14
Smith, B.L.15
Sartor, C.I.16
Leung, E.H.17
Abrams, J.18
Schilsky, R.L.19
Muss, H.B.20
Norton, L.21
more..
-
4
-
-
0023304864
-
Epidermal growth factor receptor gene expression in estrogen receptor-positive and negative human breast cancer cell lines
-
Davidson NE, Gelmann EP, Lippman ME, Dickson RB: Epidermal growth factor receptor gene expression in estrogen receptor-positive and negative human breast cancer cell lines. Mol Endocrinol 1987, 1(3): 216-223.
-
(1987)
Mol Endocrinol
, vol.1
, Issue.3
, pp. 216-223
-
-
Davidson, N.E.1
Gelmann, E.P.2
Lippman, M.E.3
Dickson, R.B.4
-
5
-
-
1842543455
-
HER-2/neu-overexpressing human breast cancer xenografts exhibit increased angiogenic potential mediated by vascular endothelial growth factor (VEGF)
-
Epstein M, Ayala R, Tchekmedyian N, Borgstrom P, Pegram DJ, Slamon DJ: HER-2/neu-overexpressing human breast cancer xenografts exhibit increased angiogenic potential mediated by vascular endothelial growth factor (VEGF). Breast Cancer Res Treat 2002, 76(suppl. 1): S143.
-
(2002)
Breast Cancer Res Treat
, vol.76
, Issue.SUPPL. 1
-
-
Epstein, M.1
Ayala, R.2
Tchekmedyian, N.3
Borgstrom, P.4
Pegram, D.J.5
Slamon, D.J.6
-
6
-
-
84879477431
-
AVEREL: a randomized phase III Trial evaluating bevacizumab in combination with docetaxel and trastuzumab as first-line therapy for HER2-positive locally recurrent/metastatic breast cancer
-
Gianni L, Romieu GH, Lichinitser M, Serrano SV, Mansutti M, Pivot X, Mariani P, Andre F, Chan A, Lipatov O, Chan S, Wardley A, Greil R, Moore N, Prot S, Pallaud C, Semiglazov V: AVEREL: a randomized phase III Trial evaluating bevacizumab in combination with docetaxel and trastuzumab as first-line therapy for HER2-positive locally recurrent/metastatic breast cancer. J Clin Oncol 2013, 31(14): 1719-1725.
-
(2013)
J Clin Oncol
, vol.31
, Issue.14
, pp. 1719-1725
-
-
Gianni, L.1
Romieu, G.H.2
Lichinitser, M.3
Serrano, S.V.4
Mansutti, M.5
Pivot, X.6
Mariani, P.7
Andre, F.8
Chan, A.9
Lipatov, O.10
Chan, S.11
Wardley, A.12
Greil, R.13
Moore, N.14
Prot, S.15
Pallaud, C.16
Semiglazov, V.17
-
7
-
-
0037445132
-
Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer
-
Henderson IC, Berry DA, Demetri GD, Cirrincione CT, Goldstein LJ, Martino S, Ingle JN, Cooper MR, Hayes DF, Tkaczuk KH, Fleming G, Holland JF, Duggan DB, Carpenter JT, Frei E 3rd, Schilsky RL, Wood WC, Muss HB, Norton L: Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer. J Clin Oncol 2003, 21(6): 976-983.
-
(2003)
J Clin Oncol
, vol.21
, Issue.6
, pp. 976-983
-
-
Henderson, I.C.1
Berry, D.A.2
Demetri, G.D.3
Cirrincione, C.T.4
Goldstein, L.J.5
Martino, S.6
Ingle, J.N.7
Cooper, M.R.8
Hayes, D.F.9
Tkaczuk, K.H.10
Fleming, G.11
Holland, J.F.12
Duggan, D.B.13
Carpenter, J.T.14
Frei 3rd, E.15
Schilsky, R.L.16
Wood, W.C.17
Muss, H.B.18
Norton, L.19
-
9
-
-
12144291334
-
Association between HER-2/neu and vascular endothelial growth factor expression predicts clinical outcome in primary breast cancer patients
-
Konecny GE, Meng YG, Untch M, Wang HJ, Bauerfeind I, Epstein M, Stieber P, Vernes JM, Gutierrez J, Hong K, Beryt M, Hepp H, Slamon DJ, Pegram MD: Association between HER-2/neu and vascular endothelial growth factor expression predicts clinical outcome in primary breast cancer patients. Clin Cancer Res 2004, 10(5): 1706-1716.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.5
, pp. 1706-1716
-
-
Konecny, G.E.1
Meng, Y.G.2
Untch, M.3
Wang, H.J.4
Bauerfeind, I.5
Epstein, M.6
Stieber, P.7
Vernes, J.M.8
Gutierrez, J.9
Hong, K.10
Beryt, M.11
Hepp, H.12
Slamon, D.J.13
Pegram, M.D.14
-
10
-
-
84871712569
-
Adjuvant docetaxel, doxorubicin, and cyclophosphamide in node-positive breast cancer: 10-year follow-up of the phase 3 randomised BCIRG 001 trial
-
Mackey JR, Martin M, Pienkowski T, Rolski J, Guastalla JP, Sami A, Glaspy J, Juhos E, Wardley A, Fornander T, Hainsworth J, Coleman R, Modiano MR, Vinholes J, Pinter T, Rodríguez-Lescure A, Colwell B, Whitlock P, Provencher L, Laing K, Walde D, Price C, Hugh JC, Childs BH, Bassi K, Lindsay MA, Wilson V, Rupin M, Houé V, Vogel C: Adjuvant docetaxel, doxorubicin, and cyclophosphamide in node-positive breast cancer: 10-year follow-up of the phase 3 randomised BCIRG 001 trial. Lancet Oncol 2013, 14(1): 72-80.
-
(2013)
Lancet Oncol
, vol.14
, Issue.1
, pp. 72-80
-
-
Mackey, J.R.1
Martin, M.2
Pienkowski, T.3
Rolski, J.4
Guastalla, J.P.5
Sami, A.6
Glaspy, J.7
Juhos, E.8
Wardley, A.9
Fornander, T.10
Hainsworth, J.11
Coleman, R.12
Modiano, M.R.13
Vinholes, J.14
Pinter, T.15
Rodríguez-Lescure, A.16
Colwell, B.17
Whitlock, P.18
Provencher, L.19
Laing, K.20
Walde, D.21
Price, C.22
Hugh, J.C.23
Childs, B.H.24
Bassi, K.25
Lindsay, M.A.26
Wilson, V.27
Rupin, M.28
Houé, V.29
Vogel, C.30
more..
-
11
-
-
15044350668
-
The expanding TOR signaling network
-
Martin DE, Hall MN: The expanding TOR signaling network. Curr Opin Cell Biol 2005, 17(2): 158-166.
-
(2005)
Curr Opin Cell Biol
, vol.17
, Issue.2
, pp. 158-166
-
-
Martin, D.E.1
Hall, M.N.2
-
12
-
-
0038688702
-
Doxorubicin in combination with fluorouracil and cyclophosphamide (i.v. FAC regimen, day 1, 21) versus methotrexate in combination with fluorouracil and cyclophosphamide (i.v. CMF regimen, day 1, 21) as adjuvant chemotherapy for operable breast cancer: a study by the GEICAM group
-
Martin M, Villar A, Sole-Calvo A, Gonzalez R, Massuti B, Lizon J, Camps C, Carrato A, Casado A, Candel MT, Albanell J, Aranda J, Munarriz B, Campbell J, Diaz-Rubio E: Doxorubicin in combination with fluorouracil and cyclophosphamide (i. v. FAC regimen, day 1, 21) versus methotrexate in combination with fluorouracil and cyclophosphamide (i. v. CMF regimen, day 1, 21) as adjuvant chemotherapy for operable breast cancer: a study by the GEICAM group. Ann Oncol 2003, 14(6): 833-842.
-
(2003)
Ann Oncol
, vol.14
, Issue.6
, pp. 833-842
-
-
Martin, M.1
Villar, A.2
Sole-Calvo, A.3
Gonzalez, R.4
Massuti, B.5
Lizon, J.6
Camps, C.7
Carrato, A.8
Casado, A.9
Candel, M.T.10
Albanell, J.11
Aranda, J.12
Munarriz, B.13
Campbell, J.14
Diaz-Rubio, E.15
-
13
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller K, Wang M, Gralow J, Dickler M, Cobleigh M, Perez EA, Shenkier T, Cella D, Davidson NE: Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007, 357(26): 2666-2676.
-
(2007)
N Engl J Med
, vol.357
, Issue.26
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
Dickler, M.4
Cobleigh, M.5
Perez, E.A.6
Shenkier, T.7
Cella, D.8
Davidson, N.E.9
-
15
-
-
2942659576
-
Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer
-
Pegram MD, Konecny GE, O'Callaghan C, Beryt M, Pietras R, Slamon DJ: Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer. J Natl Cancer Inst 2004, 96(10): 739-749.
-
(2004)
J Natl Cancer Inst
, vol.96
, Issue.10
, pp. 739-749
-
-
Pegram, M.D.1
Konecny, G.E.2
O'Callaghan, C.3
Beryt, M.4
Pietras, R.5
Slamon, D.J.6
-
16
-
-
80054883209
-
Efficacy and safety of bevacizumab in combination with docetaxel for the first-line treatment of elderly patients with locally recurrent or metastatic breast cancer: results from AVADO
-
doi: 10.1016/j.ejca.2011.06.018. Epub 2011 Jul 15. PMID: 21757334
-
Pivot X, Schneeweiss A, Verma S, Thomssen C, Passos-Coelho JL, Benedetti G, Ciruelos E, von Moos R, Chang HT, Duenne AA, Miles DW: Efficacy and safety of bevacizumab in combination with docetaxel for the first-line treatment of elderly patients with locally recurrent or metastatic breast cancer: results from AVADO. Eur J Cancer 2011, 47(16): 2387-2395. doi: 10. 1016/j. ejca. 2011. 06. 018. Epub 2011 Jul 15. PMID: 21757334.
-
(2011)
Eur J Cancer
, vol.47
, Issue.16
, pp. 2387-2395
-
-
Pivot, X.1
Schneeweiss, A.2
Verma, S.3
Thomssen, C.4
Passos-Coelho, J.L.5
Benedetti, G.6
Ciruelos, E.7
von Moos, R.8
Chang, H.T.9
Duenne, A.A.10
Miles, D.W.11
-
17
-
-
70249097518
-
RIBBON-1: Randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab (B) for first-line treatment of HER2-negative locally recurrent or metastatic breast cancer (MBC)
-
Suppl. abstr 1005
-
Robert NJ, Diéras V, Glaspy J, Brufsky A, Bondarenko I, Lipatov O, Perez E, Yardley D, Zhou X, Phan S: RIBBON-1: Randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab (B) for first-line treatment of HER2-negative locally recurrent or metastatic breast cancer (MBC). J Clin Oncol 2009, 27(15s): suppl; abstr 1005.
-
(2009)
J Clin Oncol
, vol.27
, Issue.15 s
-
-
Robert, N.J.1
Diéras, V.2
Glaspy, J.3
Brufsky, A.4
Bondarenko, I.5
Lipatov, O.6
Perez, E.7
Yardley, D.8
Zhou, X.9
Phan, S.10
-
18
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
Romond EH, Perez EA, Bryant J, Suman VJ, Geyer CE Jr, Davidson NE, Tan-Chiu E, Martino S, Paik S, Kaufman PA, Swain SM, Pisansky TM, Fehrenbacher L, Kutteh LA, Vogel VG, Visscher DW, Yothers G, Jenkins RB, Brown AM, Dakhil SR, Mamounas EP, Lingle WL, Klein PM, Ingle JN, Wolmark N: Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med 2005, 353(16): 1673-1684.
-
(2005)
N Engl J Med
, vol.353
, Issue.16
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, J.3
Suman, V.J.4
Geyer Jr., C.E.5
Davidson, N.E.6
Tan-Chiu, E.7
Martino, S.8
Paik, S.9
Kaufman, P.A.10
Swain, S.M.11
Pisansky, T.M.12
Fehrenbacher, L.13
Kutteh, L.A.14
Vogel, V.G.15
Visscher, D.W.16
Yothers, G.17
Jenkins, R.B.18
Brown, A.M.19
Dakhil, S.R.20
Mamounas, E.P.21
Lingle, W.L.22
Klein, P.M.23
Ingle, J.N.24
Wolmark, N.25
more..
-
19
-
-
84892805731
-
Cancer statistics, 2014
-
Siegel R, Ma J, Zou Z, Jemal A: Cancer statistics, 2014. CA Cancer J Clin 2014, 64(1): 9-29.
-
(2014)
CA Cancer J Clin
, vol.64
, Issue.1
, pp. 9-29
-
-
Siegel, R.1
Ma, J.2
Zou, Z.3
Jemal, A.4
-
20
-
-
85193228292
-
-
San Antonio Breast Cancer Symposium, Abstract S1-03
-
Slamon DJ, Swain SM, Buyse M, Martin M, Geyer CE, Im Y-H, Pienkowski T, Kim S-B, Robert NJ, Steger G, Crown J, Verma S, Eiermann W, Costantino JP, Im S-A, Mamounas EP, Schwartzberg L, Paterson A, Mackey JR, Provencher L, Press MF, Thirlwell M, Bee-Munteanu V, Henschel V, Crepelle-Flechais A, Wolmark N: Primary results from BETH, a phase 3 controlled study of adjuvant chemotherapy and trastuzumab ± bevacizumab in patients with HER2-positive, node-positive or high risk node-negative breast cancer. 2013. San Antonio Breast Cancer Symposium, Abstract S1-03.
-
(2013)
Primary Results from BETH, a Phase 3 Controlled Study of Adjuvant Chemotherapy and Trastuzumab ± Bevacizumab in Patients with HER2-Positive, Node-Positive Or High Risk Node-Negative Breast Cancer
-
-
Slamon, D.J.1
Swain, S.M.2
Buyse, M.3
Martin, M.4
Geyer, C.E.5
Im, Y.-H.6
Pienkowski, T.7
Kim, S.-B.8
Robert, N.J.9
Steger, G.10
Crown, J.11
Verma, S.12
Eiermann, W.13
Costantino, J.P.14
Im, S.-A.15
Mamounas, E.P.16
Schwartzberg, L.17
Paterson, A.18
Mackey, J.R.19
Provencher, L.20
Press, M.F.21
Thirlwell, M.22
Bee-Munteanu, V.23
Henschel, V.24
Crepelle-Flechais, A.25
Wolmark, N.26
more..
-
21
-
-
80053539103
-
Adjuvant trastuzumab in HER2-positive breast cancer
-
Slamon D, Eiermann W, Robert N, Pienkowski T, Martin M, Press M, Mackey J, Glaspy J, Chan A, Pawlicki M, Pinter T, Valero V, Liu MC, Sauter G, von Minckwitz G, Visco F, Bee V, Buyse M, Bendahmane B, Tabah-Fisch I, Lindsay MA, Riva A, Crown J: Adjuvant trastuzumab in HER2-positive breast cancer. N Engl J Med 2011, 365(14): 1273-1283.
-
(2011)
N Engl J Med
, vol.365
, Issue.14
, pp. 1273-1283
-
-
Slamon, D.1
Eiermann, W.2
Robert, N.3
Pienkowski, T.4
Martin, M.5
Press, M.6
Mackey, J.7
Glaspy, J.8
Chan, A.9
Pawlicki, M.10
Pinter, T.11
Valero, V.12
Liu, M.C.13
Sauter, G.14
von Minckwitz, G.15
Visco, F.16
Bee, V.17
Buyse, M.18
Bendahmane, B.19
Tabah-Fisch, I.20
Lindsay, M.A.21
Riva, A.22
Crown, J.23
more..
-
22
-
-
0035870297
-
The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors
-
Sweeney CJ, Miller KD, Sissons SE, Nozaki S, Heilman DK, Shen J, Sledge GW Jr: The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors. Cancer Res 2001, 61(8): 3369-3372.
-
(2001)
Cancer Res
, vol.61
, Issue.8
, pp. 3369-3372
-
-
Sweeney, C.J.1
Miller, K.D.2
Sissons, S.E.3
Nozaki, S.4
Heilman, D.K.5
Shen, J.6
Sledge Jr., G.W.7
-
23
-
-
84859178622
-
-
United States Food and Drug AdministrationAvailable at: Accessed March 25, 2013
-
United States Food and Drug Administration: FDA Commissioner announces Avastin decision. 2011.
-
(2011)
FDA Commissioner Announces Avastin Decision
-
-
-
24
-
-
0034691674
-
Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis
-
Yen L, You XL, Al Moustafa AE, Batist G, Hynes NE, Mader S, Meloche S, Alaoui-Jamali MA: Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulates angiogenesis. Oncogene 2000, 19(31): 3460-3469.
-
(2000)
Oncogene
, vol.19
, Issue.31
, pp. 3460-3469
-
-
Yen, L.1
You, X.L.2
Al Moustafa, A.E.3
Batist, G.4
Hynes, N.E.5
Mader, S.6
Meloche, S.7
Alaoui-Jamali, M.A.8
|