1 H NMR-based lipidomics of rodent fur: Species-specifi c lipid profi les and SCD1 inhibitor-related dermal toxicity

Journal of Lipid Research

Volumn 55, Issue 7, 2014, Pages 1366-1374

  Khandelwal, Purnima ^a   Stryker, Steven ^a   Chao, Hannguang ^b   Aranibar, Nelly ^a   Lawrence, R Michael ^b   Madireddi, Malavi ^c   Zhao, Wenjun ^c   Chen, Luping ^c   Reily, Michael D ^a  

^a Applied and Investigative Metabolomics Group   (United States)

^b Discovery Chemistry and Discovery Biology ^*  (United States)

^c BRISTOL MYERS SQUIBB   (United States)

Author keywords

Fur lipid; Fur sebum; Hamster sebum; Human sebum; Lipid class measurement; Metabolomics; Mouse sebum; Nmr assay; Rat sebum; Sebum lipid; Skin lipid; Stearoyl coA desaturase

Indexed keywords

CHOLESTA 7,24 DIEN 3BETA OL ESTER; ESTER; OXYGENASE INHIBITOR; STEAROYL COA DESATURASE 1 INHIBITOR; UNCLASSIFIED DRUG; ACYL COENZYME A DESATURASE; ENZYME INHIBITOR; SCD1 PROTEIN, MOUSE; STEAROYL-COA DESATURASE SCD-1, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY REGIONS; CONTROLLED STUDY; FEMALE; LIPID ANALYSIS; LIPID COMPOSITION; LIPIDOMICS; LIPOGENESIS; MALE; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; RAT; SEPARATION TECHNIQUE; SKIN TOXICITY; THIN LAYER CHROMATOGRAPHY; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; DRUG EFFECTS; FUR; LIPID METABOLISM; MESOCRICETUS; METABOLISM; MOUSE; NUCLEAR MAGNETIC RESONANCE; SEBACEOUS GLAND DISEASE; SPRAGUE DAWLEY RAT;

ANIMAL FUR; ANIMALS; ENZYME INHIBITORS; FEMALE; LIPID METABOLISM; MALE; MESOCRICETUS; MICE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; RATS, SPRAGUE-DAWLEY; SEBACEOUS GLAND DISEASES; STEAROYL-COA DESATURASE;

EID: 84903981076     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M049155     Document Type: Article

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