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Volumn 8, Issue , 2014, Pages 887-896

New approaches to the management of schizophrenia: Focus on aberrant hippocampal drive of dopamine pathways

Author keywords

Dopamine; GABA; Glutamate; Hippocampus; MAM rat; Schizophrenia

Indexed keywords

4 AMINOBUTYRIC ACID; ATYPICAL ANTIPSYCHOTIC AGENT; CHLORPROMAZINE; DOPAMINE; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROLEPTIC AGENT;

EID: 84903904315     PISSN: 11778881     EISSN: None     Source Type: Journal    
DOI: 10.2147/DDDT.S42708     Document Type: Review
Times cited : (31)

References (138)
  • 1
    • 4243057297 scopus 로고    scopus 로고
    • A systematic review of the incidence of schizophrenia: The distribution of rates and the influence of sex, urbanicity, migrant status and methodology
    • McGrath J, Saha S, Welham J, El Saadi O, MacCauley C, Chant D. A systematic review of the incidence of schizophrenia: the distribution of rates and the influence of sex, urbanicity, migrant status and methodology. BMC Med. 2004; 2: 13.
    • (2004) BMC Med. , vol.2 , pp. 13
    • McGrath, J.1    Saha, S.2    Welham, J.3    El Saadi, O.4    McCauley, C.5    Chant, D.6
  • 2
    • 78049511028 scopus 로고    scopus 로고
    • The epidemiology of schizophrenia: Replacing dogma with knowledge
    • Stilo SA, Murray RM. The epidemiology of schizophrenia: replacing dogma with knowledge. Dialogues Clin Neurosci. 2010; 12: 305-315.
    • (2010) Dialogues Clin Neurosci. , vol.12 , pp. 305-315
    • Stilo, S.A.1    Murray, R.M.2
  • 3
    • 0026753733 scopus 로고
    • The significance of age of onset for schizophrenia
    • DeLisi LE. The significance of age of onset for schizophrenia. Schizophren Bull. 1992; 18: 209-215.
    • (1992) Schizophren Bull. , vol.18 , pp. 209-215
    • DeLisi, L.E.1
  • 4
    • 25144456112 scopus 로고    scopus 로고
    • Effectiveness of antipsychotic drugs in patients with chronic schizophrenia
    • Lieberman JA, Stroup TS, McEvoy JP, Swartz MS, Rosenheck RA, etal. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med. 2005; 353(12): 1209-1223.
    • (2005) N Engl J Med. , vol.353 , Issue.12 , pp. 1209-1223
    • Lieberman, J.A.1    Stroup, T.S.2    McEvoy, J.P.3    Swartz, M.S.4    Rosenheck, R.A.5
  • 6
    • 78651116398 scopus 로고
    • Effect of chlorpromazine or haloperidol on formation of 3methoxytyramine and normetanephrine in mouse brain
    • Carlsson A, Lindqvist M. Effect of chlorpromazine or haloperidol on formation of 3methoxytyramine and normetanephrine in mouse brain. Acta Pharmacol Toxicol. 1963; 20: 140-144.
    • (1963) Acta Pharmacol Toxicol. , vol.20 , pp. 140-144
    • Carlsson, A.1    Lindqvist, M.2
  • 7
    • 0014717325 scopus 로고
    • Receptor activity and turnover of dopamine and noradrenaline after neuroleptics
    • Andén NE, Butcher SG, Corrodi H, Fuxe K, Ungerstedt U. Receptor activity and turnover of dopamine and noradrenaline after neuroleptics. Eur J Pharmacol. 1970; 11(3): 303-314.
    • (1970) Eur J Pharmacol. , vol.11 , Issue.3 , pp. 303-314
    • Andén, N.E.1    Butcher, S.G.2    Corrodi, H.3    Fuxe, K.4    Ungerstedt, U.5
  • 8
    • 77953755155 scopus 로고    scopus 로고
    • Review: The biological basis of antipsychotic response in schizophrenia
    • Stone JM, Raffin M, Morrison P, McGuire PK. Review: The biological basis of antipsychotic response in schizophrenia. J Psychopharmacol. 2010; 24(7): 953-964.
    • (2010) J Psychopharmacol. , vol.24 , Issue.7 , pp. 953-964
    • Stone, J.M.1    Raffin, M.2    Morrison, P.3    McGuire, P.K.4
  • 9
    • 0030689616 scopus 로고    scopus 로고
    • Evaluation of treatment-resistant schizophrenia
    • Conley RR, Buchanan RW. Evaluation of treatment-resistant schizophrenia. Schizophr Bull. 1997; 23(4): 663-674.
    • (1997) Schizophr Bull. , vol.23 , Issue.4 , pp. 663-674
    • Conley, R.R.1    Buchanan, R.W.2
  • 10
    • 84864408922 scopus 로고    scopus 로고
    • World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia, part 1: Update 2012 on the acute treatment of schizophrenia and the management of treatment resistance
    • Hasan A, Falkai P, Wobrock T, Lieberman J, Glenthoj B, etal. World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia, part 1: update 2012 on the acute treatment of schizophrenia and the management of treatment resistance. World J Biol Psychiatry. 2012; 13: 318-378.
    • (2012) World J Biol Psychiatry. , vol.13 , pp. 318-378
    • Hasan, A.1    Falkai, P.2    Wobrock, T.3    Lieberman, J.4    Glenthoj, B.5
  • 11
    • 84872356828 scopus 로고    scopus 로고
    • World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of schizophrenia, part 2: Update 2012 on the long-term treatment of schizophrenia and management of antipsychotic-induced side effects
    • Hasan A, Falkai P, Wobrock T, Lieberman J, Glenthoj B, etal. World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of schizophrenia, part 2: update 2012 on the long-term treatment of schizophrenia and management of antipsychotic-induced side effects. World J Biol Psychiatry. 2013; 149(1): 2-44.
    • (2013) World J Biol Psychiatry. , vol.149 , Issue.1 , pp. 2-44
    • Hasan, A.1    Falkai, P.2    Wobrock, T.3    Lieberman, J.4    Glenthoj, B.5
  • 12
    • 0001278077 scopus 로고    scopus 로고
    • Management of negative symptoms of schizophrenia
    • Javitt DC. Management of negative symptoms of schizophrenia. Curr Psychiatry Rep. 2001; 3(5): 413-417.
    • (2001) Curr Psychiatry Rep. , vol.3 , Issue.5 , pp. 413-417
    • Javitt, D.C.1
  • 13
    • 0031776804 scopus 로고    scopus 로고
    • The role of negative symptoms and cognitive dysfunction in schizophrenia outcome
    • Tamminga CA, Buchanan RW, Gold JM. The role of negative symptoms and cognitive dysfunction in schizophrenia outcome. Int Clin Psychopharmacol. 1998; 13 Suppl 3: S21-S26.
    • (1998) Int Clin Psychopharmacol. , vol.13 , Issue.SUPPL. 3
    • Tamminga, C.A.1    Buchanan, R.W.2    Gold, J.M.3
  • 14
    • 0028200350 scopus 로고
    • Clozapine-related tardive dyskinesia
    • Davé M. Clozapine-related tardive dyskinesia. Biol Psychiatry. 1994; 35(11): 886-887.
    • (1994) Biol Psychiatry. , vol.35 , Issue.11 , pp. 886-887
    • Davé, M.1
  • 17
    • 0013217231 scopus 로고
    • Use of chlorpromazine and reserpine in mental disorders
    • Altschule MD. Use of chlorpromazine and reserpine in mental disorders. N Engl J Med. 1956; 254(11): 515-519.
    • (1956) N Engl J Med. , vol.254 , Issue.11 , pp. 515-519
    • Altschule, M.D.1
  • 18
    • 0017255979 scopus 로고
    • Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
    • Creese I, Burt DR, Snyder SH. Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science. 1976; 192(4238): 481-483.
    • (1976) Science. , vol.192 , Issue.4238 , pp. 481-483
    • Creese, I.1    Burt, D.R.2    Snyder, S.H.3
  • 19
    • 0016592484 scopus 로고
    • Antipsychotic drugs: Direct correlation between clinical potency and presynaptic action on dopamine neurons
    • Seeman P, Lee T. Antipsychotic drugs: direct correlation between clinical potency and presynaptic action on dopamine neurons. Science. 1975; 188(4194): 1217-1219.
    • (1975) Science. , vol.188 , Issue.4194 , pp. 1217-1219
    • Seeman, P.1    Lee, T.2
  • 20
    • 12344326514 scopus 로고    scopus 로고
    • Treatments for schizophrenia: A critical review of pharmacology and mechanisms of action of antipsychotic drugs
    • Miyamoto S, Duncan GE, Marx CE, Lieberman JA. Treatments for schizophrenia: a critical review of pharmacology and mechanisms of action of antipsychotic drugs. Mol Psychiatry. 2005: 10(1): 79-104.
    • (2005) Mol Psychiatry. , vol.10 , Issue.1 , pp. 79-104
    • Miyamoto, S.1    Duncan, G.E.2    Marx, C.E.3    Lieberman, J.A.4
  • 21
    • 0015747180 scopus 로고
    • An anatomy of schizophrenia?
    • Stevens JR. An anatomy of schizophrenia? Arch Gen Psychiatry. 1973; 29(2): 177-189.
    • (1973) Arch Gen Psychiatry. , vol.29 , Issue.2 , pp. 177-189
    • Stevens, J.R.1
  • 22
    • 0021907338 scopus 로고
    • Phencyclidine-induced inhibition of rat prolactin secretion: Increased portal blood dopamine
    • Meltzer HY, Simonovic M, Gudelsky GA. Phencyclidine-induced inhibition of rat prolactin secretion: increased portal blood dopamine. Eur J Pharmacol. 1985; 110(1): 143-146.
    • (1985) Eur J Pharmacol. , vol.110 , Issue.1 , pp. 143-146
    • Meltzer, H.Y.1    Simonovic, M.2    Gudelsky, G.A.3
  • 23
    • 0023812652 scopus 로고
    • Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine
    • Kane J, Honigfeld G, Singer J, Meltzer H. Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine. Arch Gen Psychiatry. 1988; 45(9): 789-796.
    • (1988) Arch Gen Psychiatry. , vol.45 , Issue.9 , pp. 789-796
    • Kane, J.1    Honigfeld, G.2    Singer, J.3    Meltzer, H.4
  • 24
    • 0024468417 scopus 로고
    • Clinical studies on the mechanism of action of clozapine: The dopamine-serotonin hypothesis of schizophrenia
    • Meltzer HY. Clinical studies on the mechanism of action of clozapine: the dopamine-serotonin hypothesis of schizophrenia. Psychopharmacology (Berl). 1989; 99 Suppl: S18-S27.
    • (1989) Psychopharmacology (Berl). , vol.99 , Issue.SUPPL.
    • Meltzer, H.Y.1
  • 25
    • 11844286960 scopus 로고    scopus 로고
    • Mechanisms of action of second generation antipsychotic drugs in schizophrenia: Insights from brain imaging studies
    • Abi-Dargham A, Laruelle M. Mechanisms of action of second generation antipsychotic drugs in schizophrenia: insights from brain imaging studies. Eur Psychiatry. 2005; 20(1): 15-27.
    • (2005) Eur Psychiatry. , vol.20 , Issue.1 , pp. 15-27
    • Abi-Dargham, A.1    Laruelle, M.2
  • 26
    • 5444229688 scopus 로고    scopus 로고
    • Occupancy of dopamine D2 receptors by the atypical antipsychotic drugs risperidone and olanzapine: Theoretical implications
    • Frankle WG, Gil R, Hackett E, etal. Occupancy of dopamine D2 receptors by the atypical antipsychotic drugs risperidone and olanzapine: theoretical implications. Psychopharmacology (Berl). 2004; 175(4): 473-480.
    • (2004) Psychopharmacology (Berl). , vol.175 , Issue.4 , pp. 473-480
    • Frankle, W.G.1    Gil, R.2    Hackett, E.3
  • 27
    • 0041880367 scopus 로고    scopus 로고
    • Is regionally selective D2/D3 dopamine occupancy sufficient for atypical antipsychotic effect? an in vivo quantitative [123I]epidepride SPET study of amisulpride-treated patients
    • Bressan RA, Erlandsson K, Jones HM, etal. Is regionally selective D2/D3 dopamine occupancy sufficient for atypical antipsychotic effect? an in vivo quantitative [123I]epidepride SPET study of amisulpride-treated patients. Am J Psychiatry. 2003; 160(8): 1413-1420.
    • (2003) Am J Psychiatry. , vol.160 , Issue.8 , pp. 1413-1420
    • Bressan, R.A.1    Erlandsson, K.2    Jones, H.M.3
  • 28
    • 0035660215 scopus 로고    scopus 로고
    • Dopamine D(2) receptors and their role in atypical antipsychotic action: Still necessary and may even be sufficient
    • Kapur S, Remington G. Dopamine D(2) receptors and their role in atypical antipsychotic action: still necessary and may even be sufficient. Biol Psychiatry. 2001; 50(11): 873-883.
    • (2001) Biol Psychiatry. , vol.50 , Issue.11 , pp. 873-883
    • Kapur, S.1    Remington, G.2
  • 29
    • 0036221550 scopus 로고    scopus 로고
    • Atypical antipsychotics: Mechanism of action
    • Seeman P. Atypical antipsychotics: mechanism of action. Can J Psychiatry. 2002; 47(1): 27-38.
    • (2002) Can J Psychiatry. , vol.47 , Issue.1 , pp. 27-38
    • Seeman, P.1
  • 30
    • 0032977410 scopus 로고    scopus 로고
    • The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia
    • Meltzer HY, McGurk SR. The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia. Schizophren Bull. 1999; 25(5): 233-255.
    • (1999) Schizophren Bull. , vol.25 , Issue.5 , pp. 233-255
    • Meltzer, H.Y.1    McGurk, S.R.2
  • 31
    • 0031431410 scopus 로고    scopus 로고
    • The effects of risperidone on the five dimensions of schizophrenia derived by factor analysis: Combined results of the North American trials
    • Marder SR, Davis JM, Chouinard G. The effects of risperidone on the five dimensions of schizophrenia derived by factor analysis: combined results of the North American trials. J Clin Psychiatry. 1997; 58(12): 538-546.
    • (1997) J Clin Psychiatry. , vol.58 , Issue.12 , pp. 538-546
    • Marder, S.R.1    Davis, J.M.2    Chouinard, G.3
  • 32
    • 0031003781 scopus 로고    scopus 로고
    • Negative symptoms: A path analytic approach to a double-blind, placebo-and haloperidol-controlled clinical trial with olanzapine
    • Tollefson GD, Sanger TM. Negative symptoms: a path analytic approach to a double-blind, placebo-and haloperidol-controlled clinical trial with olanzapine. Am J Psychiatry. 1997; 154(4): 466-474.
    • (1997) Am J Psychiatry. , vol.154 , Issue.4 , pp. 466-474
    • Tollefson, G.D.1    Sanger, T.M.2
  • 33
    • 0033021909 scopus 로고    scopus 로고
    • The effects of atypical antipsychotic drugs on neurocognitive impairment in schizophrenia: A review and meta-analysis
    • Keefe RS, Silva SG, Perkins DO, Lieberman JA. The effects of atypical antipsychotic drugs on neurocognitive impairment in schizophrenia: a review and meta-analysis. Schizophr Bull. 1999; 25(2): 201-222.
    • (1999) Schizophr Bull. , vol.25 , Issue.2 , pp. 201-222
    • Keefe, R.S.1    Silva, S.G.2    Perkins, D.O.3    Lieberman, J.A.4
  • 34
    • 18744366088 scopus 로고    scopus 로고
    • Second-generation (atypical) antipsychotics and metabolic effects: A comprehensive literature review
    • Newcomer JW. Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review. CNS Drugs. 2005; 19 Suppl 1: 1-93.
    • (2005) CNS Drugs. , vol.19 , Issue.SUPPL. 1 , pp. 1-93
    • Newcomer, J.W.1
  • 35
    • 33749321169 scopus 로고    scopus 로고
    • Randomized controlled trial of the effect on Quality of Life of second-vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1)
    • Jones PB, Barnes TR, Davies L, etal. Randomized controlled trial of the effect on Quality of Life of second-vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1). Arch Gen Psychiatry. 2006; 63(10): 1079-1087.
    • (2006) Arch Gen Psychiatry. , vol.63 , Issue.10 , pp. 1079-1087
    • Jones, P.B.1    Barnes, T.R.2    Davies, L.3
  • 36
    • 84884161208 scopus 로고    scopus 로고
    • Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: A multiple-treatments meta-analysis
    • Leucht S, Cipriani A, Spineli L, etal. Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis. Lancet. 2013; 382(9896): 951-962.
    • (2013) Lancet. , vol.382 , Issue.9896 , pp. 951-962
    • Leucht, S.1    Cipriani, A.2    Spineli, L.3
  • 37
    • 70449641202 scopus 로고    scopus 로고
    • Second-generation antipsychotics for schizophrenia: Can we resolve the conflict?
    • Leucht S, Kissling W, Davis JM. Second-generation antipsychotics for schizophrenia: can we resolve the conflict?Psychol Med. 2009; 39(10): 1591-1602.
    • (2009) Psychol Med. , vol.39 , Issue.10 , pp. 1591-1602
    • Leucht, S.1    Kissling, W.2    Davis, J.M.3
  • 38
    • 65349120160 scopus 로고    scopus 로고
    • The dopamine hypothesis of schizophrenia: Version III-the final common pathway
    • Howes OD, Kapur S. The dopamine hypothesis of schizophrenia: version III-the final common pathway. Schizophr Bull. 2009; 35(3): 549-562.
    • (2009) Schizophr Bull. , vol.35 , Issue.3 , pp. 549-562
    • Howes, O.D.1    Kapur, S.2
  • 39
    • 0033399541 scopus 로고    scopus 로고
    • Dopamine as the wind of the psychotic fire: New evidence from brain imaging studies
    • Laruelle M, Abi-Dargham A. Dopamine as the wind of the psychotic fire: new evidence from brain imaging studies. J Psychopharmacol. 1999; 13(4): 358-371.
    • (1999) J Psychopharmacol. , vol.13 , Issue.4 , pp. 358-371
    • Laruelle, M.1    Abi-Dargham, A.2
  • 41
    • 1842523130 scopus 로고    scopus 로고
    • Do we still believe in the dopamine hypothesis? New data bring new evidence
    • Abi-Dargham A. Do we still believe in the dopamine hypothesis? New data bring new evidence. Int J Neuropsychopharmacol. 2004; 7 Suppl 1: S1-S5.
    • (2004) Int J Neuropsychopharmacol. , vol.7 , Issue.SUPPL. 1
    • Abi-Dargham, A.1
  • 42
    • 0023103235 scopus 로고
    • Provocative tests with psychostimulant drugs in schizophrenia
    • Lieberman JA, Kane JM, Alvir J. Provocative tests with psychostimulant drugs in schizophrenia. Psychopharmacology (Berl). 1987; 91(4): 415-433.
    • (1987) Psychopharmacology (Berl). , vol.91 , Issue.4 , pp. 415-433
    • Lieberman, J.A.1    Kane, J.M.2    Alvir, J.3
  • 43
    • 77649197534 scopus 로고    scopus 로고
    • Increased synaptic dopamine function in associative regions of the striatum in schizophrenia
    • Kegeles LS, Abi-Dargham A, Frankle WG, etal. Increased synaptic dopamine function in associative regions of the striatum in schizophrenia. Arch Gen Psychiatry. 2010; 67(3): 231-239.
    • (2010) Arch Gen Psychiatry. , vol.67 , Issue.3 , pp. 231-239
    • Kegeles, L.S.1    Abi-Dargham, A.2    Frankle, W.G.3
  • 44
    • 0030608782 scopus 로고    scopus 로고
    • Imaging D2 receptor occupancy by endogenous dopamine in humans
    • Laruelle M, D'Souza CD, Baldwin RM, etal. Imaging D2 receptor occupancy by endogenous dopamine in humans. Neuropsychopharmacology. 1997; 17(3): 162-174.
    • (1997) Neuropsychopharmacology. , vol.17 , Issue.3 , pp. 162-174
    • Laruelle, M.1    D'Souza, C.D.2    Baldwin, R.M.3
  • 45
    • 0033964784 scopus 로고    scopus 로고
    • Imaging extrastriatal dopamine D(2) receptor occupancy by endogenous dopamine in healthy humans
    • Fujita M, Verhoeff NP, Varrone A, etal. Imaging extrastriatal dopamine D(2) receptor occupancy by endogenous dopamine in healthy humans. Eur J Pharmacol. 2000; 387(2): 179-188.
    • (2000) Eur J Pharmacol. , vol.387 , Issue.2 , pp. 179-188
    • Fujita, M.1    Verhoeff, N.P.2    Varrone, A.3
  • 46
    • 84879507260 scopus 로고    scopus 로고
    • Presynaptic striatal dopamine dysfunction in people at ultra-high risk for psychosis: Findings in a second cohort
    • Egerton A, Chaddock CA, Winton-Brown TT, etal. Presynaptic striatal dopamine dysfunction in people at ultra-high risk for psychosis: findings in a second cohort. Biol Psychiatry. 2013; 74(2): 106-112.
    • (2013) Biol Psychiatry. , vol.74 , Issue.2 , pp. 106-112
    • Egerton, A.1    Chaddock, C.A.2    Winton-Brown, T.T.3
  • 47
    • 0742322917 scopus 로고    scopus 로고
    • Presynaptic dopaminergic dysfunction in schizophrenia: A positron emission tomographic [18F]fluorodopa study
    • McGowan S, Lawrence AD, Sales T, Quested D, Grasby P. Presynaptic dopaminergic dysfunction in schizophrenia: a positron emission tomographic [18F]fluorodopa study. Arch Gen Psychiatry. 2004; 61(2): 134-142.
    • (2004) Arch Gen Psychiatry. , vol.61 , Issue.2 , pp. 134-142
    • McGowan, S.1    Lawrence, A.D.2    Sales, T.3    Quested, D.4    Grasby, P.5
  • 48
    • 84865309293 scopus 로고    scopus 로고
    • The nature of dopamine dysfunction in schizophrenia and what this means for treatment
    • Howes OD, Kambeitz J, Kim E, etal. The nature of dopamine dysfunction in schizophrenia and what this means for treatment. Arch Gen Psychiatry. 2012; 69(8): 776-786.
    • (2012) Arch Gen Psychiatry. , vol.69 , Issue.8 , pp. 776-786
    • Howes, O.D.1    Kambeitz, J.2    Kim, E.3
  • 49
    • 0036177183 scopus 로고    scopus 로고
    • Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia
    • Meyer-Lindenberg A, Miletich RS, Kohn PD, etal. Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia. Nat Neurosci. 2002; 5(3): 267-271.
    • (2002) Nat Neurosci. , vol.5 , Issue.3 , pp. 267-271
    • Meyer-Lindenberg, A.1    Miletich, R.S.2    Kohn, P.D.3
  • 50
    • 0031837964 scopus 로고    scopus 로고
    • Perseveration and strategy in a novel spatial self-ordered sequencing task for nonhuman primates: Effects of excitotoxic lesions and dopamine depletions of the prefrontal cortex
    • Collins P, Roberts AC, Dias R, Everitt BJ, Robbins TW. Perseveration and strategy in a novel spatial self-ordered sequencing task for nonhuman primates: effects of excitotoxic lesions and dopamine depletions of the prefrontal cortex. J Cogn Neurosci. 1998; 10(3): 332-354.
    • (1998) J Cogn Neurosci. , vol.10 , Issue.3 , pp. 332-354
    • Collins, P.1    Roberts, A.C.2    Dias, R.3    Everitt, B.J.4    Robbins, T.W.5
  • 51
    • 34548723459 scopus 로고    scopus 로고
    • The dopamine transporter: A vigilant border control for psychostimulant action
    • Williams JM, Galli A. The dopamine transporter: a vigilant border control for psychostimulant action. Handb Exp Pharmacol. 2006, 215-232.
    • (2006) Handb Exp Pharmacol. , pp. 215-232
    • Williams, J.M.1    Galli, A.2
  • 52
    • 0032924127 scopus 로고    scopus 로고
    • The neuropathology of schizophrenia. A critical review of the data and their interpretation
    • Harrison PJ. The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain. 1999; 122(Pt 4): 593-624.
    • (1999) Brain. , vol.122 , Issue.PART 4 , pp. 593-624
    • Harrison, P.J.1
  • 53
    • 80052035263 scopus 로고    scopus 로고
    • Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia
    • Lodge DJ, Grace AA. Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia. Trends Pharmacol Sci. 2011; 32(9): 507-513.
    • (2011) Trends Pharmacol Sci. , vol.32 , Issue.9 , pp. 507-513
    • Lodge, D.J.1    Grace, A.A.2
  • 54
    • 0028323167 scopus 로고
    • Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses
    • Krystal JH, Karper LP, Seibyl JP, etal. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry. 1994; 51(3): 199-214.
    • (1994) Arch Gen Psychiatry. , vol.51 , Issue.3 , pp. 199-214
    • Krystal, J.H.1    Karper, L.P.2    Seibyl, J.P.3
  • 55
    • 0032903301 scopus 로고    scopus 로고
    • The neuropsychopharmacology of phencyclidine: From NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia
    • Jentsch JD, Roth RH. The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia. Neuropsychopharmacology. 1999; 20(3): 201-225.
    • (1999) Neuropsychopharmacology. , vol.20 , Issue.3 , pp. 201-225
    • Jentsch, J.D.1    Roth, R.H.2
  • 56
    • 0025952455 scopus 로고
    • Recent advances in the phencyclidine model of schizophrenia
    • Javitt DC, Zukin SR. Recent advances in the phencyclidine model of schizophrenia. Am J Psychiatry. 1991; 148(10): 1301-1308.
    • (1991) Am J Psychiatry. , vol.148 , Issue.10 , pp. 1301-1308
    • Javitt, D.C.1    Zukin, S.R.2
  • 57
    • 76749151747 scopus 로고    scopus 로고
    • Effect of subchronic phencyclidine administration on sucrose preference and hippocampal parvalbumin immunoreactivity in the rat
    • Jenkins TA, Harte MK, Reynolds GP. Effect of subchronic phencyclidine administration on sucrose preference and hippocampal parvalbumin immunoreactivity in the rat. Neurosci Lett. 2010; 471(3): 144-147.
    • (2010) Neurosci Lett. , vol.471 , Issue.3 , pp. 144-147
    • Jenkins, T.A.1    Harte, M.K.2    Reynolds, G.P.3
  • 58
    • 0032575715 scopus 로고    scopus 로고
    • Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats
    • Moghaddam B, Adams BW. Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats. Science. 1998; 281(5381): 1349-1352.
    • (1998) Science. , vol.281 , Issue.5381 , pp. 1349-1352
    • Moghaddam, B.1    Adams, B.W.2
  • 59
    • 0030900732 scopus 로고    scopus 로고
    • Activation of glutamatergic neurotransmission by ketamine: A novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex
    • Moghaddam B, Adams B, Verma A, Daly D. Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J Neurosci. 1997; 17(8): 2921-2927.
    • (1997) J Neurosci. , vol.17 , Issue.8 , pp. 2921-2927
    • Moghaddam, B.1    Adams, B.2    Verma, A.3    Daly, D.4
  • 60
    • 0018638978 scopus 로고
    • Behavioral rating scales for assessing phencyclidine-induced locomotor activity, stereotyped behavior and ataxia in rats
    • Sturgeon RD, Fessler RG, Meltzer HY. Behavioral rating scales for assessing phencyclidine-induced locomotor activity, stereotyped behavior and ataxia in rats. Eur J Pharmacol. 1979; 59(3-4): 169-179.
    • (1979) Eur J Pharmacol. , vol.59 , Issue.3-4 , pp. 169-179
    • Sturgeon, R.D.1    Fessler, R.G.2    Meltzer, H.Y.3
  • 61
    • 0028802130 scopus 로고
    • Distinct effects of d-amphetamine and phencyclidine on the social behaviour of rats
    • Sams-Dodd F. Distinct effects of d-amphetamine and phencyclidine on the social behaviour of rats. Behav Pharmacol. 1995; 6(1): 55-65.
    • (1995) Behav Pharmacol. , vol.6 , Issue.1 , pp. 55-65
    • Sams-Dodd, F.1
  • 62
    • 0030071335 scopus 로고    scopus 로고
    • Phencyclidine-induced stereotyped behaviour and social isolation in rats: A possible animal model of schizophrenia
    • Sams-Dodd F. Phencyclidine-induced stereotyped behaviour and social isolation in rats: a possible animal model of schizophrenia. Behav Pharmacol. 1996; 7(1): 3-23.
    • (1996) Behav Pharmacol. , vol.7 , Issue.1 , pp. 3-23
    • Sams-Dodd, F.1
  • 63
    • 0035137638 scopus 로고    scopus 로고
    • Phencyclidine impairs latent learning in mice: Interaction between glutamatergic systems and sigma(1) receptors
    • Noda A, Noda Y, Kamei H, etal. Phencyclidine impairs latent learning in mice: interaction between glutamatergic systems and sigma(1) receptors. Neuropsychopharmacology. 2001; 24(4): 451-460.
    • (2001) Neuropsychopharmacology. , vol.24 , Issue.4 , pp. 451-460
    • Noda, A.1    Noda, Y.2    Kamei, H.3
  • 64
    • 27144457737 scopus 로고    scopus 로고
    • Acute delta9-tetrahydrocannabinol-induced deficits in reversal learning: Neural correlates of affective inflexibility
    • Egerton A, Brett RR, Pratt JA. Acute delta9-tetrahydrocannabinol-induced deficits in reversal learning: neural correlates of affective inflexibility. Neuropsychopharmacology. 2005; 30(10): 1895-1905.
    • (2005) Neuropsychopharmacology. , vol.30 , Issue.10 , pp. 1895-1905
    • Egerton, A.1    Brett, R.R.2    Pratt, J.A.3
  • 65
    • 49549088180 scopus 로고    scopus 로고
    • Postnatal phencyclidine administration selectively reduces adult cortical parvalbumin-containing interneurons
    • Wang CZ, Yang SF, Xia Y, Johnson KM. Postnatal phencyclidine administration selectively reduces adult cortical parvalbumin-containing interneurons. Neuropsychopharmacology. 2008; 33(10): 2442-2455.
    • (2008) Neuropsychopharmacology. , vol.33 , Issue.10 , pp. 2442-2455
    • Wang, C.Z.1    Yang, S.F.2    Xia, Y.3    Johnson, K.M.4
  • 66
    • 0033588176 scopus 로고    scopus 로고
    • Mice with reduced NMDA receptor expression display behaviors related to schizophrenia
    • Mohn AR, Gainetdinov RR, Caron MG, Koller BH. Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell. 1999; 98(4): 427-436.
    • (1999) Cell. , vol.98 , Issue.4 , pp. 427-436
    • Mohn, A.R.1    Gainetdinov, R.R.2    Caron, M.G.3    Koller, B.H.4
  • 67
    • 0032126753 scopus 로고    scopus 로고
    • Reliability and state dependence of pyramidal cell-interneuron synapses in the hippocampus: An ensemble approach in the behaving rat
    • Csicsvari J, Hirase H, Czurko A, Buzsáki G. Reliability and state dependence of pyramidal cell-interneuron synapses in the hippocampus: an ensemble approach in the behaving rat. Neuron. 1998; 21(1): 179-189.
    • (1998) Neuron. , vol.21 , Issue.1 , pp. 179-189
    • Csicsvari, J.1    Hirase, H.2    Czurko, A.3    Buzsáki, G.4
  • 68
    • 0036662935 scopus 로고    scopus 로고
    • Control of feedforward dendritic inhibition by NMDA receptor-dependent spike timing in hippocampal interneurons
    • Maccaferri G, Dingledine R. Control of feedforward dendritic inhibition by NMDA receptor-dependent spike timing in hippocampal interneurons. J Neurosci. 2002; 22(13): 5462-5472.
    • (2002) J Neurosci. , vol.22 , Issue.13 , pp. 5462-5472
    • McCaferri, G.1    Dingledine, R.2
  • 69
    • 0036843574 scopus 로고    scopus 로고
    • Glutamate and glutamine measured with 4.0 T proton MRS in never-treated patients with schizophrenia and healthy volunteers
    • Théberge J, Bartha R, Drost DJ, etal. Glutamate and glutamine measured with 4.0 T proton MRS in never-treated patients with schizophrenia and healthy volunteers. Am J Psychiatry. 2002; 159(11): 1944-1946.
    • (2002) Am J Psychiatry. , vol.159 , Issue.11 , pp. 1944-1946
    • Théberge, J.1    Bartha, R.2    Drost, D.J.3
  • 70
  • 71
    • 0035007327 scopus 로고    scopus 로고
    • GABAergic interneurons: Implications for understanding schizophrenia and bipolar disorder
    • Benes FM, Berretta S. GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder. Neuropsychopharmacology. 2001; 25(1): 1-27.
    • (2001) Neuropsychopharmacology. , vol.25 , Issue.1 , pp. 1-27
    • Benes, F.M.1    Berretta, S.2
  • 72
    • 84855307242 scopus 로고    scopus 로고
    • Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia
    • Lewis DA, Curley AA, Glausier JR, Volk DW. Cortical parvalbumin interneurons and cognitive dysfunction in schizophrenia. Trends Neurosci. 2012; 35(1): 57-67.
    • (2012) Trends Neurosci. , vol.35 , Issue.1 , pp. 57-67
    • Lewis, D.A.1    Curley, A.A.2    Glausier, J.R.3    Volk, D.W.4
  • 73
    • 84856857477 scopus 로고    scopus 로고
    • Cortical basket cell dysfunction in
    • Curley AA, Lewis DA. Cortical basket cell dysfunction in J Physiol. 2012; 590(Pt 4): 715-724.
    • (2012) J Physiol. , vol.590 , Issue.PART 4 , pp. 715-724
    • Curley, A.A.1    Lewis, D.A.2
  • 74
    • 84869021995 scopus 로고    scopus 로고
    • Role of glutamic acid decarboxylase 67 in regulating cortical parvalbumin and GABA membrane transporter 1 expression: Implications for schizophrenia
    • Curley AA, Eggan SM, Lazarus MS, Huang ZJ, Volk DW, Lewis DA. Role of glutamic acid decarboxylase 67 in regulating cortical parvalbumin and GABA membrane transporter 1 expression: implications for schizophrenia. Neurobiol Dis. 2013; 50: 179-186.
    • (2013) Neurobiol Dis. , vol.50 , pp. 179-186
    • Curley, A.A.1    Eggan, S.M.2    Lazarus, M.S.3    Huang, Z.J.4    Volk, D.W.5    Lewis, D.A.6
  • 75
    • 84863201711 scopus 로고    scopus 로고
    • NMDA receptor hypofunction, parvalbumin-positive neurons, and cortical gamma oscillations in schizophrenia
    • Gonzalez-Burgos G, Lewis DA. NMDA receptor hypofunction, parvalbumin-positive neurons, and cortical gamma oscillations in schizophrenia. Schizophr Bull. 2012; 38(5): 950-957.
    • (2012) Schizophr Bull. , vol.38 , Issue.5 , pp. 950-957
    • Gonzalez-Burgos, G.1    Lewis, D.A.2
  • 76
    • 0036792159 scopus 로고    scopus 로고
    • Selective deficits in prefrontal cortical GABAergic neurons in schizophrenia defined by the presence of calcium-binding proteins
    • Beasley CL, Zhang ZJ, Patten I, Reynolds GP. Selective deficits in prefrontal cortical GABAergic neurons in schizophrenia defined by the presence of calcium-binding proteins. Biol Psychiatry. 2002; 52(7): 708-715.
    • (2002) Biol Psychiatry. , vol.52 , Issue.7 , pp. 708-715
    • Beasley, C.L.1    Zhang, Z.J.2    Patten, I.3    Reynolds, G.P.4
  • 77
    • 84856121248 scopus 로고    scopus 로고
    • Lamina-and cell-specific alterations in cortical somatostatin receptor 2 mRNA expression in schizophrenia
    • Beneyto M, Morris HM, Rovensky KC, Lewis DA. Lamina-and cell-specific alterations in cortical somatostatin receptor 2 mRNA expression in schizophrenia. Neuropharmacology. 2012; 62(3): 1598-1605.
    • (2012) Neuropharmacology. , vol.62 , Issue.3 , pp. 1598-1605
    • Beneyto, M.1    Morris, H.M.2    Rovensky, K.C.3    Lewis, D.A.4
  • 78
    • 0037705995 scopus 로고    scopus 로고
    • Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia
    • Hashimoto T, Volk DW, Eggan SM, etal. Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia. J Neurosci. 2003; 23(15): 6315-6326.
    • (2003) J Neurosci. , vol.23 , Issue.15 , pp. 6315-6326
    • Hashimoto, T.1    Volk, D.W.2    Eggan, S.M.3
  • 79
    • 0032574841 scopus 로고    scopus 로고
    • A subclass of prefrontal gamma-aminobutyric acid axon terminals are selectively altered in schizophrenia
    • Woo TU, Whitehead RE, Melchitzky DS, Lewis DA. A subclass of prefrontal gamma-aminobutyric acid axon terminals are selectively altered in schizophrenia. Proc Natl Acad Sci U S A. 1998; 95(9): 5341-5346.
    • (1998) Proc Natl Acad Sci U S A. , vol.95 , Issue.9 , pp. 5341-5346
    • Woo, T.U.1    Whitehead, R.E.2    Melchitzky, D.S.3    Lewis, D.A.4
  • 80
    • 0032744393 scopus 로고    scopus 로고
    • Alterations in chandelier neuron axon terminals in the prefrontal cortex of schizophrenic subjects
    • Pierri JN, Chaudry AS, Woo TU, Lewis DA. Alterations in chandelier neuron axon terminals in the prefrontal cortex of schizophrenic subjects. Am J Psychiatry. 1999; 156(11): 1709-1719.
    • (1999) Am J Psychiatry. , vol.156 , Issue.11 , pp. 1709-1719
    • Pierri, J.N.1    Chaudry, A.S.2    Woo, T.U.3    Lewis, D.A.4
  • 81
    • 0023546973 scopus 로고
    • Fast-spiking non-pyramidal cells in the hippocampal CA3 region, dentate gyrus and subiculum of rats
    • Kawaguchi Y, Hama K. Fast-spiking non-pyramidal cells in the hippocampal CA3 region, dentate gyrus and subiculum of rats. Brain Res. 1987; 425(2): 351-355.
    • (1987) Brain Res. , vol.425 , Issue.2 , pp. 351-355
    • Kawaguchi, Y.1    Hama, K.2
  • 82
    • 54149109208 scopus 로고    scopus 로고
    • GABA neurons and the mechanisms of network oscillations: Implications for understanding cortical dysfunction in schizophrenia
    • Gonzalez-Burgos G, Lewis DA. GABA neurons and the mechanisms of network oscillations: implications for understanding cortical dysfunction in schizophrenia. Schizophr Bull. 2008; 34(5): 944-961.
    • (2008) Schizophr Bull. , vol.34 , Issue.5 , pp. 944-961
    • Gonzalez-Burgos, G.1    Lewis, D.A.2
  • 83
    • 61449095547 scopus 로고    scopus 로고
    • A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia
    • Lodge DJ, Behrens MM, Grace AA. A loss of parvalbumin-containing interneurons is associated with diminished oscillatory activity in an animal model of schizophrenia. J Neurosci. 2009; 29(8): 2344-2354.
    • (2009) J Neurosci. , vol.29 , Issue.8 , pp. 2344-2354
    • Lodge, D.J.1    Behrens, M.M.2    Grace, A.A.3
  • 84
    • 0026034858 scopus 로고
    • The genetics of schizophrenia. Current knowledge and future directions
    • Tsuang MT, Gilbertson MW, Faraone SV. The genetics of schizophrenia. Current knowledge and future directions. Schizophr Res. 1991; 4(2): 157-171.
    • (1991) Schizophr Res. , vol.4 , Issue.2 , pp. 157-171
    • Tsuang, M.T.1    Gilbertson, M.W.2    Faraone, S.V.3
  • 86
    • 0033402229 scopus 로고    scopus 로고
    • Dimensions of psychosis in affected sibling pairs
    • Cardno AG, Jones LA, Murphy KC, etal. Dimensions of psychosis in affected sibling pairs. Schizophr Bull. 1999; 25(4): 841-850.
    • (1999) Schizophr Bull. , vol.25 , Issue.4 , pp. 841-850
    • Cardno, A.G.1    Jones, L.A.2    Murphy, K.C.3
  • 87
    • 0027373971 scopus 로고
    • Twin studies of psychiatric illness. Current status and future directions
    • Kendler KS. Twin studies of psychiatric illness. Current status and future directions. Arch Gen Psychiatry. 1993; 50(11): 905-915.
    • (1993) Arch Gen Psychiatry. , vol.50 , Issue.11 , pp. 905-915
    • Kendler, K.S.1
  • 88
    • 0344305525 scopus 로고    scopus 로고
    • Schizophrenia as a complex trait: Evidence from a meta-analysis of twin studies
    • Sullivan PF, Kendler KS, Neale MC. Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch Gen Psychiatry. 2003; 60(12): 1187-1192.
    • (2003) Arch Gen Psychiatry. , vol.60 , Issue.12 , pp. 1187-1192
    • Sullivan, P.F.1    Kendler, K.S.2    Neale, M.C.3
  • 89
    • 0029131849 scopus 로고
    • Genetic basis of schizophrenia
    • McGuffin P, Owen MJ, Farmer AE. Genetic basis of schizophrenia. Lancet. 1995; 346(8976): 678-682.
    • (1995) Lancet. , vol.346 , Issue.8976 , pp. 678-682
    • McGuffin, P.1    Owen, M.J.2    Farmer, A.E.3
  • 90
    • 0034702026 scopus 로고    scopus 로고
    • Disruption of two novel genes by a translocation co-segregating with schizophrenia
    • Millar JK, Wilson-Annan JC, Anderson S, etal. Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum Mol Genet. 2000; 9(9): 1415-1423.
    • (2000) Hum Mol Genet. , vol.9 , Issue.9 , pp. 1415-1423
    • Millar, J.K.1    Wilson-Annan, J.C.2    Anderson, S.3
  • 91
    • 84867331093 scopus 로고    scopus 로고
    • Analysis of the DISC1 translocation partner (11q14.3) in genetic risk of schizophrenia
    • Debono R, Topless R, Markie D, Black MA, Merriman TR. Analysis of the DISC1 translocation partner (11q14.3) in genetic risk of schizophrenia. Genes Brain Behav. 2012; 11(7): 859-863.
    • (2012) Genes Brain Behav. , vol.11 , Issue.7 , pp. 859-863
    • Debono, R.1    Topless, R.2    Markie, D.3    Black, M.A.4    Merriman, T.R.5
  • 92
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence
    • Harrison PJ, Weinberger DR. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence. Mol Psychiatry. 2005; 10(1): 40-68.
    • (2005) Mol Psychiatry. , vol.10 , Issue.1 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2
  • 93
    • 15044363048 scopus 로고    scopus 로고
    • The genetics of schizophrenia and bipolar disorder: Dissecting psychosis
    • Craddock N, O'Donovan MC, Owen MJ. The genetics of schizophrenia and bipolar disorder: dissecting psychosis. J Med Genet. 2005; 42(3): 193-204.
    • (2005) J Med Genet. , vol.42 , Issue.3 , pp. 193-204
    • Craddock, N.1    O'Donovan, M.C.2    Owen, M.J.3
  • 94
    • 0037308528 scopus 로고    scopus 로고
    • Genes for schizophrenia? Recent findings and their pathophysiological implications
    • Harrison PJ, Owen MJ. Genes for schizophrenia? Recent findings and their pathophysiological implications. Lancet. 2003; 361(9355): 417-419.
    • (2003) Lancet. , vol.361 , Issue.9355 , pp. 417-419
    • Harrison, P.J.1    Owen, M.J.2
  • 96
    • 84862270913 scopus 로고    scopus 로고
    • Genomic copy number variations: A breakthrough in our knowledge on schizophrenia etiology?
    • Hosak L, Silhan P, Hosakova J. Genomic copy number variations: A breakthrough in our knowledge on schizophrenia etiology? Neuro Endocrinol Lett. 2012; 33(2): 183-190.
    • (2012) Neuro Endocrinol Lett. , vol.33 , Issue.2 , pp. 183-190
    • Hosak, L.1    Silhan, P.2    Hosakova, J.3
  • 97
    • 77956192274 scopus 로고    scopus 로고
    • Common variants conferring risk of schizophrenia: A pathway analysis of GWAS data
    • Jia P, Wang L, Meltzer HY, Zhao Z. Common variants conferring risk of schizophrenia: a pathway analysis of GWAS data. Schizophr Res. 2010; 122(1-3): 38-42.
    • (2010) Schizophr Res. , vol.122 , Issue.1-3 , pp. 38-42
    • Jia, P.1    Wang, L.2    Meltzer, H.Y.3    Zhao, Z.4
  • 98
    • 80355135154 scopus 로고    scopus 로고
    • Identification of new schizophrenia susceptibility loci in an ethnically homogeneous, family-based, Arab-Israeli sample
    • Alkelai A, Lupoli S, Greenbaum L, etal. Identification of new schizophrenia susceptibility loci in an ethnically homogeneous, family-based, Arab-Israeli sample. FASEB J. 2011; 25(11): 4011-4023.
    • (2011) FASEB J. , vol.25 , Issue.11 , pp. 4011-4023
    • Alkelai, A.1    Lupoli, S.2    Greenbaum, L.3
  • 99
    • 84862648283 scopus 로고    scopus 로고
    • DOCK4 and CEACAM21 as novel schizophrenia candidate genes in the Jewish population
    • Alkelai A, Lupoli S, Greenbaum L, etal. DOCK4 and CEACAM21 as novel schizophrenia candidate genes in the Jewish population. Int J Neuropsychopharmacol. 2012; 15(4): 459-469.
    • (2012) Int J Neuropsychopharmacol. , vol.15 , Issue.4 , pp. 459-469
    • Alkelai, A.1    Lupoli, S.2    Greenbaum, L.3
  • 100
    • 77955426959 scopus 로고    scopus 로고
    • Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
    • Athanasiu L, Mattingsdal M, Kähler AK, etal. Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort. J Psychiatr Res. 2010; 44(12): 748-753.
    • (2010) J Psychiatr Res. , vol.44 , Issue.12 , pp. 748-753
    • Athanasiu, L.1    Mattingsdal, M.2    Kähler, A.K.3
  • 101
    • 79952722217 scopus 로고    scopus 로고
    • After GWAS: Searching for genetic risk for schizophrenia and bipolar disorder
    • Gershon ES, Alliey-Rodriguez N, Liu C. After GWAS: searching for genetic risk for schizophrenia and bipolar disorder. Am J Psychiatry. 2011; 168(3): 253-256.
    • (2011) Am J Psychiatry. , vol.168 , Issue.3 , pp. 253-256
    • Gershon, E.S.1    Alliey-Rodriguez, N.2    Liu, C.3
  • 102
    • 0022568602 scopus 로고
    • Postmortem evidence of structural brain changes in schizophrenia. Differences in brain weight, temporal horn area, and parahippocampal gyrus compared with affective disorder
    • Brown R, Colter N, Corsellis JA, etal. Postmortem evidence of structural brain changes in schizophrenia. Differences in brain weight, temporal horn area, and parahippocampal gyrus compared with affective disorder. Arch Gen Psychiatry. 1986; 43(1): 36-42.
    • (1986) Arch Gen Psychiatry. , vol.43 , Issue.1 , pp. 36-42
    • Brown, R.1    Colter, N.2    Corsellis, J.A.3
  • 104
    • 0027466411 scopus 로고
    • Hippocampus-amygdala volumes and psychopathology in chronic schizophrenia
    • Bogerts B, Lieberman JA, Ashtari M, etal. Hippocampus-amygdala volumes and psychopathology in chronic schizophrenia. Biol Psychiatry. 1993; 33(4): 236-246.
    • (1993) Biol Psychiatry. , vol.33 , Issue.4 , pp. 236-246
    • Bogerts, B.1    Lieberman, J.A.2    Ashtari, M.3
  • 105
    • 77956393566 scopus 로고    scopus 로고
    • Alterations of cortical GABA neurons and network oscillations in schizophrenia
    • Gonzalez-Burgos G, Hashimoto T, Lewis DA. Alterations of cortical GABA neurons and network oscillations in schizophrenia. Curr Psychiatry Rep. 2010; 12(4): 335-344.
    • (2010) Curr Psychiatry Rep. , vol.12 , Issue.4 , pp. 335-344
    • Gonzalez-Burgos, G.1    Hashimoto, T.2    Lewis, D.A.3
  • 107
    • 33746266489 scopus 로고    scopus 로고
    • A neurobehavioral systems analysis of adult rats exposed to methylazoxymethanol acetate on E17: Implications for the neuropathology of schizophrenia
    • Moore H, Jentsch JD, Ghajarnia M, Geyer MA, Grace AA. A neurobehavioral systems analysis of adult rats exposed to methylazoxymethanol acetate on E17: implications for the neuropathology of schizophrenia. Biol Psychiatry. 2006; 60(3): 253-264.
    • (2006) Biol Psychiatry. , vol.60 , Issue.3 , pp. 253-264
    • Moore, H.1    Jentsch, J.D.2    Ghajarnia, M.3    Geyer, M.A.4    Grace, A.A.5
  • 108
    • 69249224450 scopus 로고    scopus 로고
    • Gestational methylazoxymethanol acetate administration: A developmental disruption model of schizophrenia
    • Lodge DJ, Grace AA. Gestational methylazoxymethanol acetate administration: a developmental disruption model of schizophrenia. Behav Brain Res. 2009; 204(2): 306-312.
    • (2009) Behav Brain Res. , vol.204 , Issue.2 , pp. 306-312
    • Lodge, D.J.1    Grace, A.A.2
  • 109
    • 0027230454 scopus 로고
    • Timetables of neurogenesis in the human brain based on experimentally determined patterns in the rat
    • Bayer SA, Altman J, Russo RJ, Zhang X. Timetables of neurogenesis in the human brain based on experimentally determined patterns in the rat. Neurotoxicology. 1993; 14(1): 83-144.
    • (1993) Neurotoxicology. , vol.14 , Issue.1 , pp. 83-144
    • Bayer, S.A.1    Altman, J.2    Russo, R.J.3    Zhang, X.4
  • 110
    • 35448996395 scopus 로고    scopus 로고
    • Aberrant hippocampal activity underlies the dopamine dysregulation in an animal model of schizophrenia
    • Lodge DJ, Grace AA. Aberrant hippocampal activity underlies the dopamine dysregulation in an animal model of schizophrenia. J Neurosci. 2007; 27(42): 11424-11430.
    • (2007) J Neurosci. , vol.27 , Issue.42 , pp. 11424-11430
    • Lodge, D.J.1    Grace, A.A.2
  • 111
    • 84867606648 scopus 로고    scopus 로고
    • Aberrant dopamine D2-like receptor function in a rodent model of schizophrenia
    • Perez SM, Lodge DJ. Aberrant dopamine D2-like receptor function in a rodent model of schizophrenia. J Pharmacol Exp Ther. 2012; 343(2): 288-295.
    • (2012) J Pharmacol Exp Ther. , vol.343 , Issue.2 , pp. 288-295
    • Perez, S.M.1    Lodge, D.J.2
  • 112
    • 84878866859 scopus 로고    scopus 로고
    • Hippocampal deep brain stimulation reverses physiological and behavioural deficits in a rodent model of schizophrenia
    • Perez SM, Shah A, Asher A, Lodge DJ. Hippocampal deep brain stimulation reverses physiological and behavioural deficits in a rodent model of schizophrenia. Int J Neuropsychopharmacol. 2013; 16(6): 1331-1339.
    • (2013) Int J Neuropsychopharmacol. , vol.16 , Issue.6 , pp. 1331-1339
    • Perez, S.M.1    Shah, A.2    Asher, A.3    Lodge, D.J.4
  • 113
    • 84888302817 scopus 로고    scopus 로고
    • Hippocampal interneuron transplants reverse aberrant dopamine system function and behavior in a rodent model of schizophrenia
    • Perez SM, Lodge DJ. Hippocampal interneuron transplants reverse aberrant dopamine system function and behavior in a rodent model of schizophrenia. Mol Psychiatry. 2013; 18(11): 1193-1198.
    • (2013) Mol Psychiatry. , vol.18 , Issue.11 , pp. 1193-1198
    • Perez, S.M.1    Lodge, D.J.2
  • 114
    • 0035400083 scopus 로고    scopus 로고
    • Glutamatergic afferents from the hippocampus to the nucleus accumbens regulate activity of ventral tegmental area dopamine neurons
    • Floresco SB, Todd CL, Grace AA. Glutamatergic afferents from the hippocampus to the nucleus accumbens regulate activity of ventral tegmental area dopamine neurons. J Neurosci. 2001; 21(13): 4915-4922.
    • (2001) J Neurosci. , vol.21 , Issue.13 , pp. 4915-4922
    • Floresco, S.B.1    Todd, C.L.2    Grace, A.A.3
  • 115
    • 0041859307 scopus 로고    scopus 로고
    • Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission
    • Floresco SB, West AR, Ash B, Moore H, Grace AA. Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission. Nat Neurosci. 2003; 6(9): 968-973.
    • (2003) Nat Neurosci. , vol.6 , Issue.9 , pp. 968-973
    • Floresco, S.B.1    West, A.R.2    Ash, B.3    Moore, H.4    Grace, A.A.5
  • 116
    • 0020558538 scopus 로고
    • Intracellular and extracellular electrophysiology of nigral dopaminergic neurons-1. Identification and characterization
    • Grace AA, Bunney BS. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons-1. Identification and characterization. Neuroscience. 1983; 10(2): 301-315.
    • (1983) Neuroscience. , vol.10 , Issue.2 , pp. 301-315
    • Grace, A.A.1    Bunney, B.S.2
  • 117
    • 33745186452 scopus 로고    scopus 로고
    • The hippocampus modulates dopamine neuron responsivity by regulating the intensity of phasic neuron activation
    • Lodge DJ, Grace AA. The hippocampus modulates dopamine neuron responsivity by regulating the intensity of phasic neuron activation. Neuropsychopharmacology. 2006; 31(7): 1356-1361.
    • (2006) Neuropsychopharmacology. , vol.31 , Issue.7 , pp. 1356-1361
    • Lodge, D.J.1    Grace, A.A.2
  • 118
    • 69949176721 scopus 로고    scopus 로고
    • Differential targeting of the CA1 subfield of the hippocampal formation by schizophrenia and related psychotic disorders
    • Schobel SA, Lewandowski NM, Corcoran CM, etal. Differential targeting of the CA1 subfield of the hippocampal formation by schizophrenia and related psychotic disorders. Arch Gen Psychiatry. 2009; 66(9): 938-946.
    • (2009) Arch Gen Psychiatry. , vol.66 , Issue.9 , pp. 938-946
    • Schobel, S.A.1    Lewandowski, N.M.2    Corcoran, C.M.3
  • 119
    • 0032129718 scopus 로고    scopus 로고
    • Impaired recruitment of the hippocampus during conscious recollection in schizophrenia
    • Heckers S, Rauch SL, Goff D, etal. Impaired recruitment of the hippocampus during conscious recollection in schizophrenia. Nat Neurosci. 1998; 1(4): 318-323.
    • (1998) Nat Neurosci. , vol.1 , Issue.4 , pp. 318-323
    • Heckers, S.1    Rauch, S.L.2    Goff, D.3
  • 120
    • 0027297279 scopus 로고
    • Postpubertal emergence of hyperresponsiveness to stress and to amphetamine after neonatal excitotoxic hippocampal damage: A potential animal model of schizophrenia
    • Lipska BK, Jaskiw GE, Weinberger DR. Postpubertal emergence of hyperresponsiveness to stress and to amphetamine after neonatal excitotoxic hippocampal damage: a potential animal model of schizophrenia. Neuropsychopharmacology. 1993; 9(1): 67-75.
    • (1993) Neuropsychopharmacology. , vol.9 , Issue.1 , pp. 67-75
    • Lipska, B.K.1    Jaskiw, G.E.2    Weinberger, D.R.3
  • 121
    • 0035329505 scopus 로고    scopus 로고
    • Lesion size and amphetamine hyperlocomotion after neonatal ventral hippocampal lesions: More is less
    • Swerdlow NR, Halim N, Hanlon FM, Platten A, Auerbach PP. Lesion size and amphetamine hyperlocomotion after neonatal ventral hippocampal lesions: more is less. Brain Res Bull. 2001; 55(1): 71-77.
    • (2001) Brain Res Bull. , vol.55 , Issue.1 , pp. 71-77
    • Swerdlow, N.R.1    Halim, N.2    Hanlon, F.M.3    Platten, A.4    Auerbach, P.P.5
  • 122
    • 0036569197 scopus 로고    scopus 로고
    • A selective decrease in the relative density of parvalbumin-immunoreactive neurons in the hippocampus in schizophrenia
    • Zhang ZJ, Reynolds GP. A selective decrease in the relative density of parvalbumin-immunoreactive neurons in the hippocampus in schizophrenia. Schizophr Res. 2002; 55(1-2): 1-10.
    • (2002) Schizophr Res. , vol.55 , Issue.1-2 , pp. 1-10
    • Zhang, Z.J.1    Reynolds, G.P.2
  • 123
    • 84879715242 scopus 로고    scopus 로고
    • A loss of hippocampal perineuronal nets produces deficits in dopamine system function: Relevance to the positive symptoms of schizophrenia
    • Shah A, Lodge DJ. A loss of hippocampal perineuronal nets produces deficits in dopamine system function: relevance to the positive symptoms of schizophrenia. Transl Psychiatry. 2013; 3: e215.
    • (2013) Transl Psychiatry. , vol.3
    • Shah, A.1    Lodge, D.J.2
  • 124
    • 79960311058 scopus 로고    scopus 로고
    • A novel α5GABA(A)R-positive allosteric modulator reverses hyperactivation of the dopamine system in the MAM model of schizophrenia
    • Gill KM, Lodge DJ, Cook JM, Aras S, Grace AA. A novel α5GABA(A)R-positive allosteric modulator reverses hyperactivation of the dopamine system in the MAM model of schizophrenia. Neuropsychopharmacology. 2011; 36(9): 1903-1911.
    • (2011) Neuropsychopharmacology. , vol.36 , Issue.9 , pp. 1903-1911
    • Gill, K.M.1    Lodge, D.J.2    Cook, J.M.3    Aras, S.4    Grace, A.A.5
  • 125
    • 84857060431 scopus 로고    scopus 로고
    • Selective remediation of reversal learning deficits in the neurodevelopmental MAM model of schizophrenia by a novel mGlu5 positive allosteric modulator
    • Gastambide F, Cotel MC, Gilmour G, O'Neill MJ, Robbins TW, Tricklebank MD. Selective remediation of reversal learning deficits in the neurodevelopmental MAM model of schizophrenia by a novel mGlu5 positive allosteric modulator. Neuropsychopharmacology. 2012; 37(4): 1057-1066.
    • (2012) Neuropsychopharmacology. , vol.37 , Issue.4 , pp. 1057-1066
    • Gastambide, F.1    Cotel, M.C.2    Gilmour, G.3    O'Neill, M.J.4    Robbins, T.W.5    Tricklebank, M.D.6
  • 127
    • 84860761426 scopus 로고    scopus 로고
    • Polypharmacy with antipsychotics, antidepressants, or benzodiazepines and mortality in schizophrenia
    • Tiihonen J, Suokas JT, Suvisaari JM, Haukka J, Korhonen P. Polypharmacy with antipsychotics, antidepressants, or benzodiazepines and mortality in schizophrenia. Arch Gen Psychiatry. 2012; 69(5): 476-483.
    • (2012) Arch Gen Psychiatry. , vol.69 , Issue.5 , pp. 476-483
    • Tiihonen, J.1    Suokas, J.T.2    Suvisaari, J.M.3    Haukka, J.4    Korhonen, P.5
  • 128
    • 0029670123 scopus 로고    scopus 로고
    • Which GABAA-receptor subtypes really occur in the brain?
    • McKernan RM, Whiting PJ. Which GABAA-receptor subtypes really occur in the brain? Trends Neurosci. 1996; 19(4): 139-143.
    • (1996) Trends Neurosci. , vol.19 , Issue.4 , pp. 139-143
    • McKernan, R.M.1    Whiting, P.J.2
  • 129
    • 0030346304 scopus 로고    scopus 로고
    • [3H]L-655, 708, a novel ligand selective for the benzodiazepine site of GABAA receptors which contain the alpha 5 subunit
    • Quirk K, Blurton P, Fletcher S, etal. [3H]L-655, 708, a novel ligand selective for the benzodiazepine site of GABAA receptors which contain the alpha 5 subunit. Neuropharmacology. 1996; 35(9-10): 1331-1335.
    • (1996) Neuropharmacology. , vol.35 , Issue.9-10 , pp. 1331-1335
    • Quirk, K.1    Blurton, P.2    Fletcher, S.3
  • 130
    • 0024477606 scopus 로고
    • Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology
    • Pritchett DB, Sontheimer H, Shivers BD, etal. Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology. Nature. 1989; 338(6216): 582-585.
    • (1989) Nature. , vol.338 , Issue.6216 , pp. 582-585
    • Pritchett, D.B.1    Sontheimer, H.2    Shivers, B.D.3
  • 131
    • 36649032770 scopus 로고    scopus 로고
    • Forebrain and midbrain distribution of major benzodiazepine-sensitive GABAA receptor subunits in the adult C57 mouse as assessed with in situ hybridization
    • Heldt SA, Ressler KJ. Forebrain and midbrain distribution of major benzodiazepine-sensitive GABAA receptor subunits in the adult C57 mouse as assessed with in situ hybridization. Neuroscience. 2007; 150(2): 370-385.
    • (2007) Neuroscience. , vol.150 , Issue.2 , pp. 370-385
    • Heldt, S.A.1    Ressler, K.J.2
  • 132
    • 3042737033 scopus 로고    scopus 로고
    • Expression of alpha 5 GABAA receptor subunit in developing rat hippocampus
    • Ramos B, Lopez-Tellez JF, Vela J, etal. Expression of alpha 5 GABAA receptor subunit in developing rat hippocampus. Brain Res Dev Brain Res. 2004; 151(1-2): 87-98.
    • (2004) Brain Res Dev Brain Res. , vol.151 , Issue.1-2 , pp. 87-98
    • Ramos, B.1    Lopez-Tellez, J.F.2    Vela, J.3
  • 133
    • 14644402983 scopus 로고    scopus 로고
    • Deep brain stimulation for treatment-resistant depression
    • Mayberg HS, Lozano AM, Voon V, etal. Deep brain stimulation for treatment-resistant depression. Neuron. 2005; 45(5): 651-660.
    • (2005) Neuron. , vol.45 , Issue.5 , pp. 651-660
    • Mayberg, H.S.1    Lozano, A.M.2    Voon, V.3
  • 134
    • 33746023959 scopus 로고    scopus 로고
    • Obsessive-compulsive disorder: Recognition across medical settings, and treatments from behavior therapy to neurosurgery
    • Greenberg BD, Pinto A, Mancebo M, Eisen J, Rasmussen SA. Obsessive-compulsive disorder: recognition across medical settings, and treatments from behavior therapy to neurosurgery. Med Health R I. 2006; 89(5): 162-165.
    • (2006) Med Health R I. , vol.89 , Issue.5 , pp. 162-165
    • Greenberg, B.D.1    Pinto, A.2    Mancebo, M.3    Eisen, J.4    Rasmussen, S.A.5
  • 135
    • 0025976466 scopus 로고
    • Long-term suppression of tremor by chronic stimulation of the ventral intermediate thalamic nucleus
    • Benabid AL, Pollak P, Gervason C, etal. Long-term suppression of tremor by chronic stimulation of the ventral intermediate thalamic nucleus. Lancet. 1991; 337(8738): 403-406.
    • (1991) Lancet. , vol.337 , Issue.8738 , pp. 403-406
    • Benabid, A.L.1    Pollak, P.2    Gervason, C.3
  • 136
    • 34547828138 scopus 로고    scopus 로고
    • High frequency deep brain stimulation in the hippocampus modifies seizure characteristics in kindled rats
    • Wyckhuys T, De Smedt T, Claeys P, etal. High frequency deep brain stimulation in the hippocampus modifies seizure characteristics in kindled rats. Epilepsia. 2007; 48(8): 1543-1550.
    • (2007) Epilepsia. , vol.48 , Issue.8 , pp. 1543-1550
    • Wyckhuys, T.1    De Smedt, T.2    Claeys, P.3
  • 137
    • 34547841430 scopus 로고    scopus 로고
    • Deep brain stimulation in patients with refractory temporal lobe epilepsy
    • Boon P, Vonck K, De Herdt V, etal. Deep brain stimulation in patients with refractory temporal lobe epilepsy. Epilepsia. 2007; 48(8): 1551-1560.
    • (2007) Epilepsia. , vol.48 , Issue.8 , pp. 1551-1560
    • Boon, P.1    Vonck, K.2    De Herdt, V.3
  • 138
    • 34247517910 scopus 로고    scopus 로고
    • Regulation of firing of dopaminergic neurons and control of goal-directed behaviors
    • Grace AA, Floresco SB, Goto Y, Lodge DJ. Regulation of firing of dopaminergic neurons and control of goal-directed behaviors. Trends Neurosci. 2007; 30(5): 220-227.
    • (2007) Trends Neurosci. , vol.30 , Issue.5 , pp. 220-227
    • Grace, A.A.1    Floresco, S.B.2    Goto, Y.3    Lodge, D.J.4


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