Assessment of various second-line medications in addition to inhaled corticosteroid in asthma patients: A randomized controlled trial

Clinical and Experimental Pharmacology and Physiology

Volumn 41, Issue 7, 2014, Pages 509-513

  Rajanandh, Muhasaparur Ganesan ^a   Nageswari, Arcot Deenadayalu ^a   Ilango, Kaliappan ^a  

^a SRM INSTITUTE OF SCIENCE AND TECHNOLOGY   (India)

Author keywords

Asthma; Budesonide; Doxofylline; Montelukast; Tiotropium

Indexed keywords

BUDESONIDE; DOXOFYLLINE; FORMOTEROL; MONTELUKAST; SALBUTAMOL; TIOTROPIUM BROMIDE; BRONCHODILATING AGENT; CORTICOSTEROID;

ADULT; ARTICLE; ASTHMA; CONTROLLED STUDY; DRUG EFFICACY; DRUG USE; FEMALE; FOLLOW UP; FORCED EXPIRATORY VOLUME; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; MEDICATION COMPLIANCE; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; RANDOMIZED CONTROLLED TRIAL; SPIROMETRY; TREATMENT DURATION; ADOLESCENT; DRUG COMBINATION; MIDDLE AGED; YOUNG ADULT;

ADOLESCENT; ADRENAL CORTEX HORMONES; ADULT; ASTHMA; BRONCHODILATOR AGENTS; BUDESONIDE; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 84903883629     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/1440-1681.12239     Document Type: Article

References (30)

1. Diette GB, Fuhlbrigge AL, Ramey AF, Hopper A, Sajjan SG, Markson LE. Asthma severity in patients initiating controller monotherapy versus combination therapy. J. Asthma 2011; 48: 304-10.
2. 2 agonist in the treatment of moderate-to-severe persistent asthma. J. Postgrad. Med. 2010; 56: 270-4.
3. Global Initiative for Asthma (GINA). Global Strategy for Asthma Management and Prevention. 2012. Available from: http://www.ginasthma.com 2012 (accessed 16 May 2012).
4. Peters SP, Kunselman SJ, Icitovic N et al. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N. Engl. J. Med. 2010; 363: 1715-26.
5. Kerstjens HAM, Engel M, Dahl R et al. Tiotropium in asthma poorly controlled with standard combination therapy. N. Engl. J. Med. 2012; 367: 1198-207.
6. Yoshida M, Nakano T, Fukuyama S et al. Effects of tiotropium on lung function in severe asthmatics with or without emphysematous changes. Pulm. Pharmacol. Ther. 2013; 26: 159-66.
7. Molimard M, Bourcereau J, Gros VL, Bourdeix I, Leynadier F, Duroux P. Comparison between formoterol 12 mg b.i.d. and on demand salbutamol in moderate persistent asthma. Respir. Med. 2001; 95: 64-70.
8. Kamada AK, Szefler SJ, Martin RJ et al. Issues in the use of inhaled glucocorticoids. Am. J. Respir. Crit. Care Med. 1996; 153: 1739-48.
9. Busse W, Nelson H, Wolfe J, Kalberg C, Yancey SW, Richard KA. Comparison of inhaled salmeterol and oral zafirlukast in patients with asthma. J. Allergy Clin. Immunol. 1999; 103: 1075-80.
10. Greening AP, Ind PW, Northfield M, Shaw G. Added salmoterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled corticosteroid. Lancet 1994; 344: 219-24.
11. Price DB, Williams AE, Yoxall S. Salmeterol/fluticasone stable-dose treatment compared with formoterol/budesonide adjustable maintenance dosing. Impact on health-related quality of life. Respir. Res. 2007; 8: 46.
12. Kalra S, Swystun VA, Bhagat R, Cockcroft DW. Inhaled corticosteroids do not prevent the development of tolerance to the bronchoprotective effect of salmeterol. Chest 1996; 109: 953-6.
13. Bhagat R, Kalra S, Swystun VA, Cockcroft DW. Rapid onset of tolerance to the bronchoprotective effect of salmeterol. Chest 1995; 108: 1235-9.
14. O'Connor BJ, Aikman SL, Barnes PJ. Tolerance to the nonbronchodilator effects of inhaled β2-agonists in asthma. N. Engl. J. Med. 1992; 327: 1204-8.
15. Pauwels RA, Lofdahl CG, Postma DS, Pride NB, Ohlsson SV. Effect of inhaled formoterol and budesonide on exacerbation of asthma. N. Engl. J. Med. 1997; 337: 1405-11.
16. Boyce JA. The role of mast cells in asthma. Prostaglandis Leukot. Essent. Fatty Acids 2003; 69: 195-205.
17. Robinson DS. The role of the mast cell in asthma: Induction of airway hyperresponsiveness by interaction with smooth muscle? J. Allergy Clin. Immunol. 2004; 114: 58-65.
18. 4. Novel interactions in the persistence and progression of asthma. J. Allergy Clin. Immunol. 2006; 117: 577-82.
19. Rajanandh MG, Nageswari AD, Ilango K. Effect of two controller medications with inhaled corticosteroid in mild to moderate persistent asthma patients. J. Med. Sci. 2014; 14: 81-6.
20. Nakamura Y, Hoshino M, Sim JJ, Ishii K, Hosaka K, Sakamoto T. Effect of the leukotriene receptor antagonist pranlukast on cellular infiltration in the bronchial mucosa of patients with asthma. Thorax 1998; 53: 835-41.
21. Fish JE, Kemp JP, Lockey RF, Glass M, Hanby LA, Bonuccelli CM. Zafirlukast for symptomatic mild to moderate asthma: A 13 week multicenter study. Clin. Ther. 1997; 19: 675-89.
22. Kemp JP. Antileukotriene drugs as oral controller therapy for asthma. Eur. Respir. Rev. 1998; 8: 190-3.
23. Aaron SD, Vandemheen KL, Fergusson D et al. Tiotropium in combination with placebo, salmeterol, or fluticasone-salmeterol for treatment of chronic obstructive pulmonary disease: A randomized trial. Ann. Intern. Med. 2007; 146: 545-55.
24. Um SW, Yoo CG, Kim YW, Han SK, Shim YS. The combination of tiotropium and budesonide in the treatment of chronic obstructive pulmonary disease. J. Korean Med. Sci. 2007; 22: 839-45.
25. 2-agonists: Addition of montelukast in an open-label pilot study. Curr. Med. Res. Opin. 2005; 21: 863-9.
26. Virchow JC Jr, Prasse A, Naya I, Summerton L, Harris A. Zafirlukast improves asthma control in patients receiving high-dose inhaled corticosteroids. Am. J. Respir. Crit. Care Med. 2000; 162: 578-85.
27. Keith PK, Koch C, Djandji M et al. Montelukast as add-on therapy with inhaled corticosteroids or inhaled corticosteroids and long-acting beta-2-agonists in the management of patients diagnosed with asthma and concurrent allergic rhinitis (The RADAR Trial). Can. Respir. J. 2009; 16: 17-24.
28. Shah AR, Sharples LD, Solanki RN, Shah KV. Double-blind, randomized, controlled trial assessing controller medications in asthma. Respiration 2006; 73: 449-56.
29. Korn DBP, Potvin E, Dramaix M, Herbots E, Peche R. Efficacy of add-on montelukast in patients with non-controlled asthma: A Belgian open-label study. Curr. Med. Res. Opin. 2009; 25: 489-97.
30. Rajanandh MG, Nageswari AD, Ilango K. Pulmonary function assessment in mild to moderate persistent asthma patients receiving montelukast, doxofylline, and tiotropium with budesonide: a randomized controlled study. Clin. Ther. 2014; 36: 526-33.