Pulmonary function assessment in mild to moderate persistent asthma patients receiving montelukast, doxofylline, and tiotropium with budesonide: A randomized controlled study

Clinical Therapeutics

Volumn 36, Issue 4, 2014, Pages 526-533

  Rajanandh, Muhasaparur G ^a   Nageswari, Arcot D ^a   Ilango, Kaliappan ^a  

^a SRM INSTITUTE OF SCIENCE AND TECHNOLOGY   (India)

Author keywords

budesonide; doxofylline; formoterol; montelukast; tiotropium

Indexed keywords

BUDESONIDE; DOXOFYLLINE; FORMOTEROL; MONTELUKAST; TIOTROPIUM BROMIDE; ACETIC ACID DERIVATIVE; BRONCHODILATING AGENT; FORMOTEROL FUMARATE; QUINOLINE DERIVATIVE; THEOPHYLLINE;

ADULT; ARTICLE; ASTHMA; EVENING DOSAGE; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MORNING DOSAGE; OUTCOME ASSESSMENT; PHARMACEUTICAL CARE; PILOT STUDY; RANDOMIZED CONTROLLED TRIAL; ANALOGS AND DERIVATIVES; CONTROLLED STUDY; DRUG COMBINATION; DRUG EFFECTS; LUNG FUNCTION TEST; PATHOPHYSIOLOGY; PHYSIOLOGY;

ACETATES; ADULT; ASTHMA; BRONCHODILATOR AGENTS; BUDESONIDE; DRUG THERAPY, COMBINATION; FEMALE; FORCED EXPIRATORY VOLUME; FORMOTEROL FUMARATE; HUMANS; MALE; MIDDLE AGED; QUINOLINES; RESPIRATORY FUNCTION TESTS; THEOPHYLLINE; TIOTROPIUM BROMIDE;

EID: 84898925474     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2014.02.006     Document Type: Article

References (28)

1. G.B. Diette, A.L. Fuhlbrigge, A.F. Ramey, A. Hopper, S.G. Sajjan, and L.E. Markson Asthma severity in patients initiating controller monotherapy versus combination therapy J Asthma 48 2011 304 310
2. 2 agonist in the treatment of moderate-to-severe persistent asthma J Postgrad Med 56 2010 270 274
3. Global Initiative for Asthma (GINA). 2012. Global strategy for asthma management and prevention. http://www.ginasthma.com. Accessed March 22, 2013.
4. S.P. Peters, S.J. Kunselman, and N. Icitovic et al. Tiotropium bromide step-up therapy for adults with uncontrolled asthma N Engl J Med 363 2010 1715 1726
5. H.A.M. Kerstjens, M. Engel, and R. Dahl et al. Tiotropium in asthma poorly controlled with standard combination therapy N Engl J Med 367 2012 1198 1207
6. M. Yoshida, T. Nakano, and S. Fukuyama et al. Effects of tiotropium on lung function in severe asthmatics with or without emphysematous changes Pulm Pharmacol Ther 26 2013 159 166
7. M.L. Levy, M. Thomas, I. Small, L. Pearce, H. Pinnock, and P. Stephenson Summary of the 2008 BTS/SIGN British Guideline on the management of asthma 18 2009 S1 S16 Prim Care Respir J 18 2009 S1 S16
8. C.R. Jenkins, F.C. Thien, J.R. Wheatley, and H.K. Reddel Traditional and patient-centred outcomes with three classes of asthma medication Eur Respir J 26 2005 36 44 (Pubitemid 40945929)
9. A.P. Greening, P.W. Ind, M. Northfield, and G. Shaw Added salmoterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled corticosteroid Lancet 344 1994 219 224 (Pubitemid 24229008)
10. R.A. Pauwels, C.G. Lofdahl, D.S. Postma, N.B. Pride, and S.V. Ohlsson Effect of inhaled formoterol and budesonide on exacerbation of asthma N Engl J Med 337 1997 1405 1411 (Pubitemid 27497887)
11. U.G. Lalloo, J. Malolepszy, and D. Kozma et al. Budesonide and formoterol in a single inhaler improves asthma control compared with increasing the dose of corticosteroid in adults with mild-to-moderate asthma Chest 123 2003 1480 1487
12. P. Calverley, R. Paulwels, and J. Vestbo et al. Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomized controlled trial Lancet 361 2003 449 456 (Pubitemid 36173708)
13. D.B. Price, A.E. Williams, and S. Yoxall Salmeterol/fluticasone stable-dose treatment compared with formoterol/budesonide adjustable maintenance dosing: impact on health-related quality of life Respir Res 4 2007 46
14. J.A. Boyce The role of mast cells in asthma Prostaglandins Leukot Essent Fatty Acids 69 2003 195 205 (Pubitemid 36980620)
15. D.S. Robinson The role of the mast cell in asthma: induction of airway hyperresponsiveness by interaction with smooth muscle? J Allergy Clin Immunol 114 2004 58 65 (Pubitemid 39005118)
16. E.W. Gelfand, and A. Dakhama CD8+ T lymphocytes and leukotriene B4: novel interactions in the persistence and progression of asthma J Allergy Clin Immunol 117 2006 577 582 (Pubitemid 43340221)
17. A.R. Leff Regulation of leukotrienes in the management of asthma: biology and clinical therapy Annu Rev Med 52 2001 1 14 (Pubitemid 32195311)
18. O. Akbari, J.L. Faul, and E.G. Hoyte et al. CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma N Engl J Med 354 2006 1117 1129
19. P.K. Keith, C. Koch, and M. Djandji et al. Montelukast as add-on therapy with inhaled corticosteroids or inhaled corticosteroids and long-acting beta-2-agonists in the management of patients diagnosed with asthma and concurrent allergic rhinitis (The RADAR Trial) Can Respir J 16 2009 17 24
20. J.C. Virchow, A. Mehta, L.i. Ljungblad, and H. Mitfessel Add-on montelukast in inadequately controlled asthma patients in a 6-month open-label study: the Montelukast In Chronic Asthma (MONICA) study Respir Med 104 2010 644 651
21. S. Joos, A. Miksch, and J. Szecsenyi et al. montelukast as add-on therapy to inhaled corticosteroids in the treatment of mild to moderate asthma: a systematic review Thorax 63 2008 453 462 (Pubitemid 351698876)
22. S.D. Aaron, K.L. Vandemheen, and D. Fergusson et al. Tiotropium in combination with placebo, salmeterol, or fluticasone-salmeterol for treatment of chronic obstructive pulmonary disease: a randomized trial Ann Intern Med 146 2007 545 555 (Pubitemid 351650535)
23. S.W. Um, C.G. Yoo, Y.W. Kim, S.K. Han, and Y.S. Shim The combination of tiotropium and budesonide in the treatment of chronic obstructive pulmonary disease J Korean Med Sci 22 2007 839 845
24. J.C. Virchow Jr, A. Prasse, I. Naya, L. Summerton, and A. Harris Zafirlukast improves asthma control in patients receiving high-dose inhaled corticosteroids Am J Respir Crit Care Med 162 2000 578 585 (Pubitemid 30647203)
25. 2-agonists: addition of montelukast in an open-label pilot study Curr Med Res Opin 21 2005 863 869 (Pubitemid 40896234)
26. A.R. Shah, L.D. Sharples, R.N. Solanki, and K.V. Shah Double-blind, randomized, controlled trial assessing controller medications in asthma Respiration 73 2006 449 456
27. D. Korn, B.P. Van den, E. Potvin, M. Dramaix, E. Herbots, and R. Peche Efficacy of add-on montelukast in patients with non-controlled asthma: a Belgian open-label study Curr Med Res Opin 25 2009 489 497
28. E.F. Juniper, M.E. Wisniewski, F.M. Cox, A.H. Emmett, K.E. Nielsen, and P.M. O' Relationship between quality of life and clinical status in asthma: a factor analysis Eur Respir J 23 2004 287 291 (Pubitemid 38195516)