Sinoporphyrin sodium, a novel sensitizer, triggers mitochondrial-dependent apoptosis in ECA-109 cells via production of reactive oxygen species

International Journal of Nanomedicine

Volumn 9, Issue 1, 2014, Pages 3077-3090

  Wang, Haiping ^a   Wang, Xiaobing ^a   Zhang, Shaoliang ^b   Wang, Pan ^a   Zhang, Kun ^a   Liu, Quanhong ^a  

^a SHAANXI NORMAL UNIVERSITY   (China)

^b Qinglong High Tech Co Ltd   (China)

Author keywords

Apoptosis; ECA 109 cells; Mitochondrial damage; Reactive oxygen species; Sinoporphyrin sodium; Sonodynamic therapy

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANNEXIN; CYTOCHROME C; DACTINOMYCIN; HEMATOPORPHYRIN; PHOTOFRIN II; PHOTOSENSITIZING AGENT; PROTOPORPHYRIN; REACTIVE OXYGEN METABOLITE; SINGLET OXYGEN; SINOPORPHYRIN SODIUM; UNCLASSIFIED DRUG; PORPHYRIN; RADIOSENSITIZING AGENT;

APOPTOSIS; ARTICLE; AUTOFLUORESCENCE; CANCER CELL DESTRUCTION; CANCER CELL LINE; CELL DAMAGE; CELL ULTRASTRUCTURE; CELL VIABILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; ESOPHAGUS CANCER; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; OXIDATIVE STRESS; PROTEIN SECRETION; SCANNING ELECTRON MICROSCOPY; SONODYNAMIC THERAPY; ULTRASOUND THERAPY; WESTERN BLOTTING; CELL LINE; CELL SHAPE; CHEMISTRY; DRUG EFFECTS; INTRACELLULAR SPACE; METABOLISM; SOUND; TUMOR CELL LINE;

APOPTOSIS; CELL LINE; CELL LINE, TUMOR; CELL SHAPE; CYTOCHROMES C; HUMANS; INTRACELLULAR SPACE; MITOCHONDRIA; PORPHYRINS; RADIATION-SENSITIZING AGENTS; REACTIVE OXYGEN SPECIES; SOUND;

EID: 84903879321     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S59302     Document Type: Article

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