Anti-dengue-virus activity and structure-activity relationship studies of lycorine derivatives

ChemMedChem

Volumn 9, Issue 7, 2014, Pages 1522-1533

  Wang, Peng ^a   Li, Lin Feng ^a   Wang, Qing Yin ^b   Shang, Lu Qing ^a   Shi, Pei Yong ^b   Yin, Zheng ^a  

^a NANKAI UNIVERSITY   (China)

^b NOVARTIS INSTITUTE FOR TROPICAL DISEASES   (Singapore)

Author keywords

alkaloids; antiviral agents; dengue virus; lycorine; structure activity relationships

Indexed keywords

1 ACETYL 2 (BOC GLY)LYCORINE; 1 ACETYL 2 (GLUTARIC ACID)LYCORINE; 1 ACETYL 2 HYDROXYLAMINELYCORINE; 1 ACETYL 2 N HYDROXYPHTHALIMIDELYCORINE; 1 ACETYL 2 OXOLYCORINE; 1 ACETYL 2 PHENYLLYCORINE; 1 ACETYL 2 PROPIONYLLYCORINE; 1 ACETYLLYCORINE; 1 BENZOYL 2 OXOLYCORINE; 1 PROPIONYL 2 OXOLYCORINE; 1,2 ALPHA EPOXYLYCORINE; 1,2 DIACETYLLYCORINE; 12 METHYL 12 (4 AMINOBENZOYL)LYCORINE; 12 METHYL 12 (4 NITROBENZOYL)LYCORINE; 12,12 DIMETHYLLYCORINE; 2 (4 PENTANETRIAZOLE)LYCORINE; 2 (4 PHENYLTRIAZOLE)LYCORINE; 2 ACETYLLYCORINE; 2 AMINOLYCORINE; 2 AZIDOLYCORINE; 2 HEXANOYLLYCORINE; 2 METHOXYLYCORINE; 2 OXOLYCORINE; 2 TERT BUTYLDIMETHYLSILYLOXYLYCORINE; 8,9 NOR 1,2,8,9 TETRAACETYLLYCORINE; 8,9 NOR 8,9 DIHYDROXYLLYCORINE; ANTIVIRUS AGENT; LYCORINE; UNCLASSIFIED DRUG; AMARYLLIDACEAE ALKALOID; PHENANTHRIDINE DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHIRALITY; COMPARATIVE MOLECULAR FIELD ANALYSIS; CONTROLLED STUDY; CYTOTOXICITY; DENGUE VIRUS; DRUG SYNTHESIS; ESTERIFICATION; IMMUNODETECTION; MITSUNOBU REACTION; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; NUCLEOPHILICITY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; CHEMISTRY; CONFORMATION; DRUG EFFECTS; SYNTHESIS;

AMARYLLIDACEAE ALKALOIDS; ANTIVIRAL AGENTS; DENGUE VIRUS; MOLECULAR CONFORMATION; PHENANTHRIDINES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84903820725     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201300505     Document Type: Article

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