메뉴 건너뛰기




Volumn 73, Issue 6, 2014, Pages 1285-1293

Pharmacokinetics and exposure-effect relationships of capecitabine in elderly patients with breast or colorectal cancer

Author keywords

Capecitabine; Elderly; Pharmacokinetics; Response

Indexed keywords

CAPECITABINE; DRUG METABOLITE;

EID: 84903819474     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-014-2466-0     Document Type: Article
Times cited : (15)

References (29)
  • 6
    • 0028302620 scopus 로고
    • Pharmacokinetics of drugs in the elderly
    • Woodhouse KW (1994) Pharmacokinetics of drugs in the elderly. J R Soc Med 87:2-4
    • (1994) J R Soc Med , vol.87 , pp. 2-4
    • Woodhouse, K.W.1
  • 7
    • 0042707810 scopus 로고    scopus 로고
    • When drug therapy gets old: Pharmacokinetics and pharmacodynamics in the elderly
    • Turnheim K (2003) When drug therapy gets old: pharmacokinetics and pharmacodynamics in the elderly. Exp Gerontol 38:843-853
    • (2003) Exp Gerontol , vol.38 , pp. 843-853
    • Turnheim, K.1
  • 8
    • 0034792770 scopus 로고    scopus 로고
    • Vision of the future: Capecitabine
    • Twelves C (2001) Vision of the future: capecitabine. Oncologist 6:35-39
    • (2001) Oncologist , vol.6 , pp. 35-39
    • Twelves, C.1
  • 9
    • 0032127244 scopus 로고    scopus 로고
    • Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5 fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue
    • DOI 10.1016/S0959-8049(98)00058-6, PII S0959804998000586
    • Miwa M, Ura M, Nishida M, Sawada N, Ishikawa T, Mori K et al (1998) Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue. Eur J Cancer 34:1274-1281 (Pubitemid 28342121)
    • (1998) European Journal of Cancer , vol.34 , Issue.8 , pp. 1274-1281
    • Miwa, M.1    Ura, M.2    Nishida, M.3    Sawada, N.4    Ishikawa, T.5    Mori, K.6    Shimma, N.7    Umeda, I.8    Ishitsuka, H.9
  • 10
    • 0037352930 scopus 로고    scopus 로고
    • Population pharmacokinetics and concentration-effect relationships of capecitabine metabolites in colorectal cancer patients
    • DOI 10.1046/j.1365-2125.2003.01765.x
    • Gieschke R, Burger H-U, Reigner B, Blesch KS, Steimer J-L (2003) Population pharmacokinetics and concentration-effect relationships of capecitabine metabolites in colorectal cancer patients. Br J Clin Pharmacol 55:252-263 (Pubitemid 36390755)
    • (2003) British Journal of Clinical Pharmacology , vol.55 , Issue.3 , pp. 252-263
    • Gieschke, R.1    Burger, H.-U.2    Reigner, B.3    Blesch, K.S.4    Steimer, J.-L.5
  • 13
    • 84885184871 scopus 로고    scopus 로고
    • Higher capecitabine AUC in elderly patients with advanced colorectal cancer (SWOGS0030)
    • Louie SG, Ely B, Lenz H-J, Albain KS, Gotay C, Coleman D et al (2013) Higher capecitabine AUC in elderly patients with advanced colorectal cancer (SWOGS0030). Br J Cancer 109:1744-1749
    • (2013) Br J Cancer , vol.109 , pp. 1744-1749
    • Louie, S.G.1    Ely, B.2    Lenz, H.-J.3    Albain, K.S.4    Gotay, C.5    Coleman, D.6
  • 15
    • 28844485700 scopus 로고    scopus 로고
    • Pharmacokinetic modelling of 5-FU production from capecitabine - A population study in 40 adult patients with metastatic cancer
    • DOI 10.1007/s10928-005-0018-2
    • Urien S, Rezaí K, Lokiec F (2005) Pharmacokinetic modelling of 5-FU production from capecitabine-a population study in 40 adult patients with metastatic cancer. J Pharmacokinet Pharmacodyn 32:817-833 (Pubitemid 41772359)
    • (2005) Journal of Pharmacokinetics and Pharmacodynamics , vol.32 , Issue.5-6 , pp. 817-833
    • Urien, S.1    Rezai, K.2    Lokiec, F.3
  • 16
    • 84875612508 scopus 로고    scopus 로고
    • Biweekly XELOX (capecitabine and oxaliplatin) as first-line treatment in elderly patients with metastatic colorectal cancer
    • Grande C, Quintero G, Candamio S, París Bouzas L, Villanueva MJ, Campos B et al (2013) Biweekly XELOX (capecitabine and oxaliplatin) as first-line treatment in elderly patients with metastatic colorectal cancer. J Geriatr Oncol 4:114-121
    • (2013) J Geriatr Oncol , vol.4 , pp. 114-121
    • Grande, C.1    Quintero, G.2    Candamio, S.3    París Bouzas, L.4    Villanueva, M.J.5    Campos, B.6
  • 17
    • 84884700039 scopus 로고    scopus 로고
    • Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): An open-label, randomised phase 3 trial
    • Cunningham D, Lang I, Marcuello E, Lorusso V, Ocvirk J, Shin DB et al (2013) Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): an open-label, randomised phase 3 trial. Lancet Oncol 14:1077-1085
    • (2013) Lancet Oncol , vol.14 , pp. 1077-1085
    • Cunningham, D.1    Lang, I.2    Marcuello, E.3    Lorusso, V.4    Ocvirk, J.5    Shin, D.B.6
  • 18
    • 84878749207 scopus 로고    scopus 로고
    • Cognitive function in older women with breast cancer treated with standard chemotherapy and capecitabine on Cancer and Leukemia Group B 49907
    • Freedman RA, Pitcher B, Keating NL, Ballman KV, Mandelblatt J, Kornblith AB et al (2013) Cognitive function in older women with breast cancer treated with standard chemotherapy and capecitabine on Cancer and Leukemia Group B 49907. Breast Cancer Res Treat 139:607-616
    • (2013) Breast Cancer Res Treat , vol.139 , pp. 607-616
    • Freedman, R.A.1    Pitcher, B.2    Keating, N.L.3    Ballman, K.V.4    Mandelblatt, J.5    Kornblith, A.B.6
  • 21
    • 0016916438 scopus 로고
    • Prediction of creatinine clearance from serum creatinine
    • Cockcroft DW, Gault MH (1976) Prediction of creatinine clearance from serum creatinine. Nephron 16:31-41
    • (1976) Nephron , vol.16 , pp. 31-41
    • Cockcroft, D.W.1    Gault, M.H.2
  • 22
    • 0031890613 scopus 로고    scopus 로고
    • Co-variables influencing 5-fluorouracil clearance during continuous venous infusion. A NONMEM analysis
    • DOI 10.1016/S0959-8049(97)00345-6, PII S0959804997003456
    • Etienne MC, Chatelut E, Pivot X, Lavit M, Pujol A, Canal P et al (1998) Co-variables influencing 5-fluorouracil clearance during continuous venous infusion. A NONMEM analysis. Eur J Cancer 34:92-97 (Pubitemid 28123387)
    • (1998) European Journal of Cancer , vol.34 , Issue.1 , pp. 92-97
    • Etienne, M.-C.1    Chatelut, E.2    Pivot, X.3    Lavit, M.4    Pujol, A.5    Canal, P.6    Milano, G.7
  • 23
    • 0033120135 scopus 로고    scopus 로고
    • A procedure for generating bootstrap samples for the validation of nonlinear mixed-effects population models
    • DOI 10.1016/S0169-2607(98)00098-4, PII S0169260798000984
    • Parke J, Holford NH, Charles BG (1999) A procedure for generating bootstrap samples for the validation of nonlinear mixed-effects population models. Comput Methods Programs Biomed 59:19-29 (Pubitemid 29125558)
    • (1999) Computer Methods and Programs in Biomedicine , vol.59 , Issue.1 , pp. 19-29
    • Parke, J.1    Holford, N.H.G.2    Charles, B.G.3
  • 28
    • 0036174497 scopus 로고    scopus 로고
    • Incidence and severity of hand-foot syndrome in colorectal cancer patients treated with capecitabine: A single-institution experience
    • DOI 10.1081/CNV-120000360
    • Abushullaih S, Saad ED, Munsell M, Hoff PM (2002) Incidence and severity of hand-foot syndrome in colorectal cancer patients treated with capecitabine: a single-institution experience. Cancer Invest 20:3-10 (Pubitemid 34151055)
    • (2002) Cancer Investigation , vol.20 , Issue.1 , pp. 3-10
    • Abushullaih, S.1    Saad, E.D.2    Munsell, M.3    Hoff, P.M.4
  • 29
    • 0031982748 scopus 로고    scopus 로고
    • Population pharmacokinetics/pharmacodynamics of docetaxel in phase II studies in patients with cancer
    • Bruno R, Hille D, Riva A, Vivier N, ten Bokkel Huinnink WW, van Oosterom AT et al (1998) Population pharmacokinetics/pharmacodynamics of docetaxel in phase II studies in patients with cancer. J Clin Oncol 16:187-196
    • (1998) J Clin Oncol , vol.16 , pp. 187-196
    • Bruno, R.1    Hille, D.2    Riva, A.3    Vivier, N.4    Ten Bokkel Huinnink, W.W.5    Van Oosterom, A.T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.