-
1
-
-
77955635233
-
Cancer statistics
-
Jemal A, Siegel R, Xu J, Ward E (2010) Cancer statistics. CA Cancer J Clin 60(5):277-300
-
(2010)
CA Cancer J Clin
, vol.60
, Issue.5
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
2
-
-
84888857719
-
Is age a risk factor of postoperative complications in colorectal cancer?
-
Wydra J, Kruszewski W, Jasiński W, Szajewski M, Ciesielski M, Szefel J et al (2013) Is age a risk factor of postoperative complications in colorectal cancer? Pol Przegl Chir 85:491-495
-
(2013)
Pol Przegl Chir
, vol.85
, pp. 491-495
-
-
Wydra, J.1
Kruszewski, W.2
Jasiński, W.3
Szajewski, M.4
Ciesielski, M.5
Szefel, J.6
-
3
-
-
36549075573
-
Management of breast cancer in elderly individuals: Recommendations of the International Society of Geriatric Oncology
-
DOI 10.1016/S1470-2045(07)70378-9, PII S1470204507703789
-
Wildiers H, Kunkler I, Biganzoli L, Fracheboud J, Vlastos G, Bernard-Marty C et al (2007) Management of breast cancer in elderly individuals: recommendations of the International Society of Geriatric Oncology. Lancet Oncol 8:1101-1115 (Pubitemid 350182967)
-
(2007)
Lancet Oncology
, vol.8
, Issue.12
, pp. 1101-1115
-
-
Wildiers, H.1
Kunkler, I.2
Biganzoli, L.3
Fracheboud, J.4
Vlastos, G.5
Bernard-Marty, C.6
Hurria, A.7
Extermann, M.8
Girre, V.9
Brain, E.10
Audisio, R.A.11
Bartelink, H.12
Barton, M.13
Giordano, S.H.14
Muss, H.15
Aapro, M.16
-
4
-
-
0033619959
-
Underrepresentation of patients 65 years of age or older in cancer- treatment trials
-
DOI 10.1056/NEJM199912303412706
-
Hutchins LF, Unger JM, Crowley JJ, Coltman CA Jr, Albain KS (1999) Underrepresentation of patients 65 years of age or older in cancer-treatment trials. N Engl J Med 341:2061-2067 (Pubitemid 30035956)
-
(1999)
New England Journal of Medicine
, vol.341
, Issue.27
, pp. 2061-2067
-
-
Hutchins, L.F.1
Unger, J.M.2
Crowley, J.J.3
Coltman Jr., C.A.4
Albain, K.S.5
-
5
-
-
0038662715
-
Participation of patients 65 years of age or older in cancer clinical trials
-
DOI 10.1200/JCO.2003.08.010
-
Lewis JH, Kilgore ML, Goldman DP, Trimble EL, Kaplan R, Montello MJ et al (2003) Participation of patients 65 years of age or older in cancer clinical trials. J Clin Oncol 21:1383-1389 (Pubitemid 46606420)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.7
, pp. 1383-1389
-
-
Lewis, J.H.1
Kilgore, M.L.2
Goldman, D.P.3
Trimble, E.L.4
Kaplan, R.5
Montello, M.J.6
Housman, M.G.7
Escarce, J.J.8
-
6
-
-
0028302620
-
Pharmacokinetics of drugs in the elderly
-
Woodhouse KW (1994) Pharmacokinetics of drugs in the elderly. J R Soc Med 87:2-4
-
(1994)
J R Soc Med
, vol.87
, pp. 2-4
-
-
Woodhouse, K.W.1
-
7
-
-
0042707810
-
When drug therapy gets old: Pharmacokinetics and pharmacodynamics in the elderly
-
Turnheim K (2003) When drug therapy gets old: pharmacokinetics and pharmacodynamics in the elderly. Exp Gerontol 38:843-853
-
(2003)
Exp Gerontol
, vol.38
, pp. 843-853
-
-
Turnheim, K.1
-
8
-
-
0034792770
-
Vision of the future: Capecitabine
-
Twelves C (2001) Vision of the future: capecitabine. Oncologist 6:35-39
-
(2001)
Oncologist
, vol.6
, pp. 35-39
-
-
Twelves, C.1
-
9
-
-
0032127244
-
Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5 fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue
-
DOI 10.1016/S0959-8049(98)00058-6, PII S0959804998000586
-
Miwa M, Ura M, Nishida M, Sawada N, Ishikawa T, Mori K et al (1998) Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue. Eur J Cancer 34:1274-1281 (Pubitemid 28342121)
-
(1998)
European Journal of Cancer
, vol.34
, Issue.8
, pp. 1274-1281
-
-
Miwa, M.1
Ura, M.2
Nishida, M.3
Sawada, N.4
Ishikawa, T.5
Mori, K.6
Shimma, N.7
Umeda, I.8
Ishitsuka, H.9
-
10
-
-
0037352930
-
Population pharmacokinetics and concentration-effect relationships of capecitabine metabolites in colorectal cancer patients
-
DOI 10.1046/j.1365-2125.2003.01765.x
-
Gieschke R, Burger H-U, Reigner B, Blesch KS, Steimer J-L (2003) Population pharmacokinetics and concentration-effect relationships of capecitabine metabolites in colorectal cancer patients. Br J Clin Pharmacol 55:252-263 (Pubitemid 36390755)
-
(2003)
British Journal of Clinical Pharmacology
, vol.55
, Issue.3
, pp. 252-263
-
-
Gieschke, R.1
Burger, H.-U.2
Reigner, B.3
Blesch, K.S.4
Steimer, J.-L.5
-
11
-
-
0032874167
-
14C-labelled drug
-
DOI 10.1023/A:1006263400888
-
Judson IR, Beale PJ, Trigo JM, Aherne W, Crompton T, Jones D et al (1999) A human capecitabine excretion balance and pharmacokinetic study after administration of a single oral dose of 14C-labelled drug. Invest New Drugs 17:49-56 (Pubitemid 29452747)
-
(1999)
Investigational New Drugs
, vol.17
, Issue.1
, pp. 49-56
-
-
Judson, I.R.1
Beale, P.J.2
Trigo, J.M.3
Aherne, W.4
Crompton, T.5
Jones, D.6
Bush, E.7
Reigner, B.8
-
13
-
-
84885184871
-
Higher capecitabine AUC in elderly patients with advanced colorectal cancer (SWOGS0030)
-
Louie SG, Ely B, Lenz H-J, Albain KS, Gotay C, Coleman D et al (2013) Higher capecitabine AUC in elderly patients with advanced colorectal cancer (SWOGS0030). Br J Cancer 109:1744-1749
-
(2013)
Br J Cancer
, vol.109
, pp. 1744-1749
-
-
Louie, S.G.1
Ely, B.2
Lenz, H.-J.3
Albain, K.S.4
Gotay, C.5
Coleman, D.6
-
14
-
-
0036021792
-
Population pharmacokinetic analysis of the major metabolites of capecitabine
-
DOI 10.1023/A:1015716617967
-
Gieschke R, Reigner B, Blesch KS, Steimer JL (2002) Population pharmacokinetic analysis of the major metabolites of capecitabine. J Pharmacokinet Pharmacodyn 29:25-47 (Pubitemid 34831931)
-
(2002)
Journal of Pharmacokinetics and Pharmacodynamics
, vol.29
, Issue.1
, pp. 25-47
-
-
Gieschke, R.1
Reigner, B.2
Blesch, K.S.3
Steimer, J.-L.4
-
15
-
-
28844485700
-
Pharmacokinetic modelling of 5-FU production from capecitabine - A population study in 40 adult patients with metastatic cancer
-
DOI 10.1007/s10928-005-0018-2
-
Urien S, Rezaí K, Lokiec F (2005) Pharmacokinetic modelling of 5-FU production from capecitabine-a population study in 40 adult patients with metastatic cancer. J Pharmacokinet Pharmacodyn 32:817-833 (Pubitemid 41772359)
-
(2005)
Journal of Pharmacokinetics and Pharmacodynamics
, vol.32
, Issue.5-6
, pp. 817-833
-
-
Urien, S.1
Rezai, K.2
Lokiec, F.3
-
16
-
-
84875612508
-
Biweekly XELOX (capecitabine and oxaliplatin) as first-line treatment in elderly patients with metastatic colorectal cancer
-
Grande C, Quintero G, Candamio S, París Bouzas L, Villanueva MJ, Campos B et al (2013) Biweekly XELOX (capecitabine and oxaliplatin) as first-line treatment in elderly patients with metastatic colorectal cancer. J Geriatr Oncol 4:114-121
-
(2013)
J Geriatr Oncol
, vol.4
, pp. 114-121
-
-
Grande, C.1
Quintero, G.2
Candamio, S.3
París Bouzas, L.4
Villanueva, M.J.5
Campos, B.6
-
17
-
-
84884700039
-
Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): An open-label, randomised phase 3 trial
-
Cunningham D, Lang I, Marcuello E, Lorusso V, Ocvirk J, Shin DB et al (2013) Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): an open-label, randomised phase 3 trial. Lancet Oncol 14:1077-1085
-
(2013)
Lancet Oncol
, vol.14
, pp. 1077-1085
-
-
Cunningham, D.1
Lang, I.2
Marcuello, E.3
Lorusso, V.4
Ocvirk, J.5
Shin, D.B.6
-
18
-
-
84878749207
-
Cognitive function in older women with breast cancer treated with standard chemotherapy and capecitabine on Cancer and Leukemia Group B 49907
-
Freedman RA, Pitcher B, Keating NL, Ballman KV, Mandelblatt J, Kornblith AB et al (2013) Cognitive function in older women with breast cancer treated with standard chemotherapy and capecitabine on Cancer and Leukemia Group B 49907. Breast Cancer Res Treat 139:607-616
-
(2013)
Breast Cancer Res Treat
, vol.139
, pp. 607-616
-
-
Freedman, R.A.1
Pitcher, B.2
Keating, N.L.3
Ballman, K.V.4
Mandelblatt, J.5
Kornblith, A.B.6
-
19
-
-
43949096593
-
PK/PD model of indisulam and capecitabine: Interaction causes excessive myelosuppression
-
DOI 10.1038/sj.clpt.6100344, PII 6100344
-
Zandvliet AS, Siegel-Lakhai WS, Beijnen JH, Copalu W, Etienne-Grimaldi M-C, Milano G et al (2008) PK/PD model of indisulam and capecitabine: interaction causes excessive myelosuppression. Clin Pharmacol Ther 83:829-839 (Pubitemid 351704912)
-
(2008)
Clinical Pharmacology and Therapeutics
, vol.83
, Issue.6
, pp. 829-839
-
-
Zandvliet, A.S.1
Siegel-Lakhai, W.S.2
Beijnen, J.H.3
Copalu, W.4
Etienne-Grimaldi, M.-C.5
Milano, G.6
Schellens, J.H.M.7
Huitema, A.D.R.8
-
21
-
-
0016916438
-
Prediction of creatinine clearance from serum creatinine
-
Cockcroft DW, Gault MH (1976) Prediction of creatinine clearance from serum creatinine. Nephron 16:31-41
-
(1976)
Nephron
, vol.16
, pp. 31-41
-
-
Cockcroft, D.W.1
Gault, M.H.2
-
22
-
-
0031890613
-
Co-variables influencing 5-fluorouracil clearance during continuous venous infusion. A NONMEM analysis
-
DOI 10.1016/S0959-8049(97)00345-6, PII S0959804997003456
-
Etienne MC, Chatelut E, Pivot X, Lavit M, Pujol A, Canal P et al (1998) Co-variables influencing 5-fluorouracil clearance during continuous venous infusion. A NONMEM analysis. Eur J Cancer 34:92-97 (Pubitemid 28123387)
-
(1998)
European Journal of Cancer
, vol.34
, Issue.1
, pp. 92-97
-
-
Etienne, M.-C.1
Chatelut, E.2
Pivot, X.3
Lavit, M.4
Pujol, A.5
Canal, P.6
Milano, G.7
-
23
-
-
0033120135
-
A procedure for generating bootstrap samples for the validation of nonlinear mixed-effects population models
-
DOI 10.1016/S0169-2607(98)00098-4, PII S0169260798000984
-
Parke J, Holford NH, Charles BG (1999) A procedure for generating bootstrap samples for the validation of nonlinear mixed-effects population models. Comput Methods Programs Biomed 59:19-29 (Pubitemid 29125558)
-
(1999)
Computer Methods and Programs in Biomedicine
, vol.59
, Issue.1
, pp. 19-29
-
-
Parke, J.1
Holford, N.H.G.2
Charles, B.G.3
-
24
-
-
0033834414
-
Dose and time dependencies of 5-fluorouracil pharmacokinetics
-
Terret C, Erdociain E, Guimbaud R, Boisdron-Celle M, McLeod HL, Féty-Deporte R et al (2000) Dose and time dependencies of 5-fluorouracil pharmacokinetics. Clin Pharmacol Ther 68:270-279
-
(2000)
Clin Pharmacol Ther
, vol.68
, pp. 270-279
-
-
Terret, C.1
Erdociain, E.2
Guimbaud, R.3
Boisdron-Celle, M.4
McLeod, H.L.5
Féty-Deporte, R.6
-
25
-
-
0031696544
-
Clinical impact of pharmacokinetically-guided dose adaptation of 5- fluorouracil: Results from a multicentric randomized trial in patients with locally advanced head and neck carcinomas
-
Fety R, Rolland F, Barberi-Heyob M, Hardoin A, Campion L, Conroy T et al (1998) Clinical impact of pharmacokinetically-guided dose adaptation of 5-fluorouracil: results from a multicentric randomized trial in patients with locally advanced head and neck carcinoma. Clin Cancer Res 4:2039-2045 (Pubitemid 28415645)
-
(1998)
Clinical Cancer Research
, vol.4
, Issue.9
, pp. 2039-2045
-
-
Fety, R.1
Rolland, F.2
Barberi-Heyob, M.3
Hardouin, A.4
Campion, L.5
Conroy, T.6
Merlin, J.-L.7
Riviere, A.8
Perrocheau, G.9
Etienne, M.-C.10
Milano, G.11
-
26
-
-
0036185589
-
Effect of renal impairment on the pharmacokinetics and tolerability of capecitabine (Xeloda) in cancer patients
-
DOI 10.1007/s00280-001-0408-0
-
Poole C, Gardiner J, Twelves C, Johnston P, Harper P, Cassidy J et al (2002) Effect of renal impairment on the pharmacokinetics and tolerability of capecitabine (Xeloda) in cancer patients. Cancer Chemother Pharmacol 49:225-234 (Pubitemid 34185596)
-
(2002)
Cancer Chemotherapy and Pharmacology
, vol.49
, Issue.3
, pp. 225-234
-
-
Poole, C.1
Gardiner, J.2
Twelves, C.3
Johnston, P.4
Harper, P.5
Cassidy, J.6
Monkhouse, J.7
Banken, L.8
Weidekamm, E.9
Reigner, B.10
-
27
-
-
0033050165
-
Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer
-
Blum JL, Jones SE, Buzdar AU, LoRusso PM, Kuter I, Vogel C et al (1999) Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer. J Clin Oncol 7:485-493 (Pubitemid 29075232)
-
(1999)
Journal of Clinical Oncology
, vol.17
, Issue.2
, pp. 485-493
-
-
Blum, J.L.1
Jones, S.E.2
Buzdar, A.U.3
LoRusso, P.M.4
Kuter, I.5
Vogel, C.6
Osterwalder, B.7
Burger, H.-U.8
Brown, C.S.9
Griffin, T.10
-
28
-
-
0036174497
-
Incidence and severity of hand-foot syndrome in colorectal cancer patients treated with capecitabine: A single-institution experience
-
DOI 10.1081/CNV-120000360
-
Abushullaih S, Saad ED, Munsell M, Hoff PM (2002) Incidence and severity of hand-foot syndrome in colorectal cancer patients treated with capecitabine: a single-institution experience. Cancer Invest 20:3-10 (Pubitemid 34151055)
-
(2002)
Cancer Investigation
, vol.20
, Issue.1
, pp. 3-10
-
-
Abushullaih, S.1
Saad, E.D.2
Munsell, M.3
Hoff, P.M.4
-
29
-
-
0031982748
-
Population pharmacokinetics/pharmacodynamics of docetaxel in phase II studies in patients with cancer
-
Bruno R, Hille D, Riva A, Vivier N, ten Bokkel Huinnink WW, van Oosterom AT et al (1998) Population pharmacokinetics/pharmacodynamics of docetaxel in phase II studies in patients with cancer. J Clin Oncol 16:187-196
-
(1998)
J Clin Oncol
, vol.16
, pp. 187-196
-
-
Bruno, R.1
Hille, D.2
Riva, A.3
Vivier, N.4
Ten Bokkel Huinnink, W.W.5
Van Oosterom, A.T.6
|