Pharmacokinetic modelling of 5-FU production from capecitabine - A population study in 40 adult patients with metastatic cancer

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 32, Issue 5-6, 2005, Pages 817-833

  Urien, Saik ^a,b   Rezaí, Keyvan ^a   Lokiec, François ^a  

^a CENTRE RENÉ HUGUENIN   (France)

^b INSERM   (France)

Author keywords

5 FU; Anticancer drugs; Capecitabine; Drug metabolism; Population pharmacokinetics

Indexed keywords

5' DEOXY 5 FLUOROCYTIDINE; BILIRUBIN; CAPECITABINE; DOXIFLURIDINE; FLUOROURACIL;

ADULT; ARTICLE; BILIRUBIN BLOOD LEVEL; BLOOD SAMPLING; CANCER PATIENT; CLINICAL ARTICLE; CLINICAL TRIAL; COMPUTER PROGRAM; DEMOGRAPHY; DOSE TIME EFFECT RELATION; DRUG ABSORPTION; DRUG DISPOSITION; DRUG ELIMINATION; DRUG STRUCTURE; DRUG TRANSFORMATION; FEMALE; FIRST PASS EFFECT; HUMAN; MALE; METASTASIS; NONPARAMETRIC TEST; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; VALIDATION PROCESS;

EID: 28844485700     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10928-005-0018-2     Document Type: Article

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