Anticancer potential of (pentamethylcyclopentadienyl)chloridoiridium(III) complexes bearing κp and κp,κS-coordinated Ph 2PCH2CH2CH2S(O)xPh (x=0-2) ligands

ChemMedChem

Volumn 9, Issue 7, 2014, Pages 1586-1593

  Ludwig, Gerd ^a   Randelovic̈, Ivan ^b   Maksimovic̈ Ivanic̈, Danijela ^b   Mijatovic̈, Sanja ^b   Bulatovic̈, Mirna Z ^b   Miljkovic̈, Djordje ^b   Korb, Marcus ^c   Lang, Heinrich ^c   Steinborn, Dirk ^a   Kaluderovic̈, Goran N ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF BELGRADE   (Serbia)

^c CHEMNITZ UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

apoptosis; cytotoxic agents; iridium(III) complexes; metal based drugs; sulfur functionalized phosphorus ligands

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; IRIDIUM COMPLEX; COORDINATION COMPOUND; IRIDIUM; LIGAND; REACTIVE OXYGEN METABOLITE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST ADENOCARCINOMA; COLON ADENOCARCINOMA; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MELANOMA CELL LINE; PRIORITY JOURNAL; SUBMANDIBULAR CARCINOMA; THYROID CARCINOMA; X RAY DIFFRACTION; CELL CYCLE CHECKPOINT; CELL SURVIVAL; CHEMISTRY; CONFORMATION; DRUG EFFECTS; MCF 7 CELL LINE; METABOLISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE; X RAY CRYSTALLOGRAPHY;

ANTINEOPLASTIC AGENTS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL SURVIVAL; COORDINATION COMPLEXES; CRYSTALLOGRAPHY, X-RAY; HUMANS; IRIDIUM; LIGANDS; MCF-7 CELLS; MOLECULAR CONFORMATION; REACTIVE OXYGEN SPECIES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84903816795     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201300479     Document Type: Article

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