Collagen cross-linking with photoactivated riboflavin (PACK-CXL) for the treatment of advanced infectious keratitis with corneal melting

Ophthalmology

Volumn 121, Issue 7, 2014, Pages 1377-1382

  Said, Dalia G ^a   Elalfy, Mohamed S ^a   Gatzioufas, Zisis ^b   El Zakzouk, Ehab S ^a   Hassan, Mansour A ^c   Saif, Mohamed Y ^c   Zaki, Ahmed A ^a   Dua, Harminder S ^d   Hafezi, Farhad ^b,e  

^a RESEARCH INSTITUTE OF OPHTHALMOLOGY   (Egypt)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c Birmingham Children's Hospital   (Egypt)

^d NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^e UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CEFTAZIDIME; COLLAGEN; GLYCEROL; ITRACONAZOLE; RIBOFLAVIN; VANCOMYCIN;

ADULT; ANTIMICROBIAL THERAPY; ARTICLE; CHROMATOPHORE; CLINICAL ARTICLE; CLINICAL TRIAL; COLLAGEN CROSS LINKAGE; CORNEA DISEASE; CORNEA PERFORATION; CORNEA THICKNESS; CORNEA ULCER; CORNEAL MELTING; CROSS LINKING; EYE EXAMINATION; FEMALE; HEALING; HUMAN; INFECTIOUS KERATITIS; KERATITIS; MALE; PHOTOACTIVATED CHROMOPHORE FOR INFECTIOUS KERATITIS; PHOTOACTIVATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECURRENT INFECTION; SLIT LAMP; TREATMENT DURATION; VISUAL ACUITY;

ADULT; ANTI-BACTERIAL AGENTS; COLLAGEN; CORNEAL STROMA; CORNEAL ULCER; CROSS-LINKING REAGENTS; EYE INFECTIONS; FEMALE; HUMANS; MALE; MIDDLE AGED; PHOTOSENSITIZING AGENTS; PROSPECTIVE STUDIES; RIBOFLAVIN; TIME FACTORS; TREATMENT OUTCOME; ULTRAVIOLET RAYS; VISUAL ACUITY;

EID: 84903816476     PISSN: 01616420     EISSN: 15494713     Source Type: Journal    
DOI: 10.1016/j.ophtha.2014.01.011     Document Type: Article

References (30)

1. D.B. Jones Decision-making in the management of microbial keratitis Ophthalmology 88 1981 814 820 (Pubitemid 11039470)
2. American Academy of Ophthalmology Cornea/External Disease Panel. Preferred Practice Pattern Guidelines. Bacterial Keratitis. Available at: http://one.aao.org/CE/PracticeGuidelines/PPP.aspx. Accessed November 8, 2013.
3. H.G. Bennett, J. Hay, and C.M. Kirkness et al. Antimicrobial management of presumed microbial keratitis: guidelines for treatment of central and peripheral ulcers Br J Ophthalmol 82 1998 137 145 (Pubitemid 28176987)
4. G.P. DeMuri, and M.K. Hostetter Resistance to antifungal agents Pediatr Clin North Am 42 1995 665 685
5. S.B. Levy Multidrug resistance - a sign of the times N Engl J Med 338 1998 1376 1378
6. H.C. Neu The crisis in antibiotic resistance Science 257 1992 1064 1073
7. F.J. Ollivier, B.C. Gilger, and K.P. Barrie et al. Proteinases of the cornea and preocular tear film Vet Ophthalmol 10 2007 199 206 (Pubitemid 46906338)
8. M.E. Fini, M.T. Girard, and M. Matsubara Collagenolytic/gelatinolytic enzymes in corneal wound healing Acta Ophthalmol Suppl 202 1992 26 33
9. M.E. Fini, W.C. Parks, and W.B. Rinehart et al. Role of matrix metalloproteinases in failure to re-epithelialize after corneal injury Am J Pathol 149 1996 1287 1302 (Pubitemid 26337246)
10. J.T. Daniels, G. Geerling, and R.A. Alexander et al. Temporal and spatial expression of matrix metalloproteinases during wound healing of human corneal tissue Exp Eye Res 77 2003 653 664 (Pubitemid 37373579)
11. F. Hafezi, J. Kanellopoulos, R. Wiltfang, and T. Seiler Corneal collagen crosslinking with riboflavin and ultraviolet A to treat induced keratectasia after laser in situ keratomileusis J Cataract Refract Surg 33 2007 2035 2040 (Pubitemid 350167516)
12. P. Vinciguerra, E. Albe, and A.M. Mahmoud et al. Intra- and postoperative variation in ocular response analyzer parameters in keratoconic eyes after corneal cross-linking J Refract Surg 26 2010 669 676
13. G. Wollensak, E. Spoerl, and T. Seiler Riboflavin/ultraviolet-A-induced collagen crosslinking for the treatment of keratoconus Am J Ophthalmol 135 2003 620 627 (Pubitemid 36457967)
14. S.A. Martins, J.C. Combs, and G. Noguera et al. Antimicrobial efficacy of riboflavin/UVA combination (365 nm) in vitro for bacterial and fungal isolates: a potential new treatment for infectious keratitis Invest Ophthalmol Vis Sci 49 2008 3402 3408
15. H.P. Iseli, M.A. Thiel, and F. Hafezi et al. Ultraviolet A/riboflavin corneal cross-linking for infectious keratitis associated with corneal melts Cornea 27 2008 590 594
16. K. Makdoumi, J. Mortensen, and S. Crafoord Infectious keratitis treated with corneal crosslinking Cornea 29 2010 1353 1358
17. A. Panda, S.N. Krishna, and S. Kumar Photo-activated riboflavin therapy of refractory corneal ulcers Cornea 31 2012 1210 1213
18. A. Shah, A. Sachdev, D. Coggon, and P. Hossain Geographic variations in microbial keratitis: an analysis of the peer-reviewed literature Br J Ophthalmol 95 2011 762 767
19. P.A. Thomas, and P. Geraldine Infectious keratitis Curr Opin Infect Dis 20 2007 129 141 (Pubitemid 46340794)
20. V. Kozobolis, G. Labiris, and M. Gkika et al. UV-A collagen cross-linking treatment of bullous keratopathy combined with corneal ulcer Cornea 29 2010 235 238
21. A. Skaat, D. Zadok, and Y. Goldich et al. Riboflavin/UVA photochemical therapy for severe infectious keratitis Eur J Ophthalmol 24 2014 21 28
22. G.D. Kymionis, V.P. Kankariya, and G.A. Kontadakis Combined treatment with flap amputation, phototherapeutic keratectomy, and collagen crosslinking in severe intractable post-LASIK atypical mycobacterial infection with corneal melt J Cataract Refract Surg 38 2012 713 715
23. Z. Li, V. Jhanji, and X. Tao et al. Riboflavin/ultraviolet light-mediated crosslinking for fungal keratitis [letter] Br J Ophthalmol 97 2013 669 671
24. T. Micelli Ferrari, M. Leozappa, and M. Lorusso et al. Escherichia coli keratitis treated with ultraviolet A/riboflavin corneal cross-linking: a case report Eur J Ophthalmol 19 2009 295 297
25. J.C. Hurley Antibiotic-induced release of endotoxin. A therapeutic paradox Drug Saf 12 1995 183 195
26. J.A. Hobden Pseudomonas aeruginosa proteases and corneal virulence DNA Cell Biol 21 2002 391 396 (Pubitemid 35034581)
27. K. Matsumoto Role of bacterial proteases in pseudomonal and serratial keratitis Biol Chem 385 2004 1007 1016 (Pubitemid 39600308)
28. E. Spoerl, G. Wollensak, and T. Seiler Increased resistance of crosslinked cornea against enzymatic digestion Curr Eye Res 29 2004 35 40 (Pubitemid 39389439)
29. M.Q. Salomao, S.S. Chaurasia, and A. Sinha-Roy et al. Corneal wound healing after ultraviolet-A/riboflavin collagen cross-linking: a rabbit study J Refract Surg 27 2011 401 407
30. A. Sauer, V. Letscher-Bru, and C. Speeg-Schatz et al. In vitro efficacy of antifungal treatment using riboflavin/UV-A (365 nm) combination and amphotericin B Invest Ophthalmol Vis Sci 51 2010 3950 3953