Role of matrix metalloproteinases in failure to re-epithelialize after corneal injury

American Journal of Pathology

Volumn 149, Issue 4, 1996, Pages 1287-1302

  Fini, M Elizabeth ^a,h   Parks, William C ^b   Rinehart, William B ^a   Girard, Marie T ^c,d   Matsubara, Masao ^c,d   Cook, Jeffery R ^a   West Mays, Judith A ^a   Sadow, Peter M ^a   Burgeson, Robert E ^c,d   Jeffrey, John J ^e   Raizman, Michael B ^a   Krueger, Ronald R ^f   Zieske, James D ^g  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e ALBANY MEDICAL COLLEGE   (United States)

^f SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^h TUFTS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; GELATINASE B; STROMELYSIN;

ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; CORNEA EPITHELIUM; CORNEA INJURY; CORNEA ULCER; ENZYME SYNTHESIS; EPITHELIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; RAT; THERMAL INJURY; TISSUE REPAIR; WOUND HEALING;

ANIMALS; BASEMENT MEMBRANE; COLLAGENASES; CORNEA; CORNEAL ULCER; GELATINASES; HUMANS; MATRIX METALLOPROTEINASE 3; METALLOENDOPEPTIDASES; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; WOUND HEALING;

EID: 10144262630     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Berman MB: Collagenase and corneal ulceration. Collagenase in Normal and Pathological Connective Tissues. Edited by DE Wooley, JM Evanson. Chichester, UK, John Wiley, 1980, pp 141-174
2. Foster CS, Zeit RP, Mai-Phan T, Kenyon KR: Immunosuppression and selective inflammatory cell depletion: studies on a guinea pig model of corneal ulceration after alkali burning. Arch Ophthalmol 1982, 100:1820-1824
3. Berman M, Kenyon K, Hayashi K, L'Hernault N: The pathogenesis of epithelial defects in stromal ulceration. The Cornea: Transactions of the World Congress on the Cornea III. Edited by HD Cavanagh. New York, Raven Press, 1988, pp 35-43
4. Matsubara M, Zieske JD, Fini ME: Mechanism of basement membrane dissolution preceding corneal ulceration. Invest Ophthalmol Vis Sci 1991, 32:3221-3237
5. Alexander CM, Werb Z: Proteinases and extracellular matrix remodelling. Curr Opin Cell Biol 1989, 1:974-982
6. Fini ME, Girard MT: Expression of collagenolytic/gelatinolytic metalloproteinases by normal cornea. Invest Ophthalmol Vis Sci 1990, 31:1779-1788
7. Fini ME, Girard MT: The pattern of metalloproteinase expression by corneal fibroblasts is altered with passage in cell culture. J Cell Sci 1990, 97:373-383
8. Fini ME, Yue BYJT, Sugar J: Collagenolytic/gelatinolytic enzymes in normal and keratoconus corneas. Curr Eye Res 1992, 11:849-862
9. Matsubara M, Zieske JD, Girard MT, Kublin CL, Cintron C, Fini ME: Differential roles for two gelatinolytic enzymes of the matrix metalloproteinase family in the remodeling cornea. Dev Biol 1991, 147:425-439
10. Girard MT, Matsubara M, Kublin C, Tessier M, Cintron C, Fini ME: Stromal fibroblasts synthesize collagenase and stromelysin during long-term remodeling of repair tissue. J Cell Sci 1993, 104:1001-1011
11. Gasset AR, Shaw EL, Kaufman HE, Itoi M, Sakimoto T, Ishii Y: Thermokeratoplasty. Trans Am Acad Ophthalmol 1973, 77:441-454
12. Conn H, Berman M, Kenyon K, Langer R, Gage J: Stromal vascularization prevents corneal ulceration. Invest Ophthalmol Vis Sci 1980, 19:362-370
13. Zieske JD, Bukusoglu G, Gipson IK: Enhancement of vinculin synthesis by migrating stratified epithelium. J Cell Biol 1989, 109:571-576
14. Sakai LY, Keene DR, Morris NP, Burgeson RE: Type VII collagen is a major component of anchoring fibrils. J Cell Biol 1986, 103:1577-1586
15. Rouselle P, Lunstum GP, Keene DR, Burgeson RE: Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments, J Cell Biol 1991, 114:567-576
16. Heussen C, Dowdle EB: Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates. Anal Biochem 1980, 102:196-202
17. Girard ME, Matsubara M, Fini ME: Transforming growth factor-β and IL-1 modulate expression of metalloproteinases by corneal stromal cells. Invest Ophthalmol Vis Sci 1991, 32:2441-2454
18. Quinn CO, Scott DK, Brinckerhoff CE, Matrisian LM, Jeffrey JJ, Partridge NC: Rat collagenase: cloning, amino acid sequence comparison, and parathyroid hormone regulation in osteoblastic cells. J Biol Chem 1990, 265:22342-22347
19. Roswit WT, Halme J, Jeffrey JJ: Purification and properties of rat uterine procollagenase. Arch Biochem Biophys 1983, 225:285-295
20. Lyons JG, Birkedal-Hansen B, Moore WGI, O'Grady RL, Birkedal-Hansen H: Characteristics of a 95-kDa matrix metalloproteinase produced by mammary carcinoma cells. Biochemistry 1991, 30:1449-1456
21. Brinckerhoff CE, Fini ME, Ruby PL, Plucinska IM. Borges KM, Karmilowicz MJ: Coordinate regulation of metalloproteinase gene expression in synovial cells. Development and Diseases of Cartilage and Bone Matrix. Edited by A Sen, T Thornhill. New York, Alan R Liss, 1987, pp 299-317
22. Blair HC, Teitelbaum SL, Ehlich S, Jeffrey JJ: Collagenase production by smooth muscle: correlation of immunoreactive with functional enzyme in myometrium. J Cell Physiol 1986, 129:111-123
23. Saarialho-Kere UK, Kovacs SO, Pentland AP, Olerud JE, Welgus HG, Parks WC: Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing. J Clin Invest 1993, 92:2858-2866
24. Saarialho-Kere UK, Chang ES, Welgus HG, Parks WC: Distinct localization of collagenase and tissue inhibitor of metalloproteinases expression in wound healing associated with ulcerative pyogenic granuloma. J Clin Invest 1993, 90:1952-1957
25. Saarialho-Kere UK, Pentland AP, Birkedal-Hansen H, Parks WC, Welgus HG: Distinct populations of basal keratinocytes express stromelysin-1 and stromelysin-2 in chronic wounds. J Clin Invest 1994, 94:79-88
26. Goldberg GI, Wilhelm SM, Kronberger A, Bauer EA, Grant GA, Eisen AZ: Human fibroblast collagenase: complete primary structure and homology to an oncogene transformation-induced protein. J Biol Chem 1986, 261:6600-6605
27. Wilhelm SM, Collier IE, Marmer BL, Eisen AZ, Grant GA, Goldberg GI: SV-40 transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages. J Biol Chem 1989, 264:17213-17221
28. Stahle-Backdahl M, Parks WC: 92 kDa gelatinase is actively expressed by eosinophils and stored by neutrophils in squamous cell carcinoma. Am J Pathol 1993, 142:995-1000
29. Grobelny D, Poncz L, Galardy RE: Inhibition of human skin fibroblast collagenase, thermolysin, and Pseudomonas aeruginosa elastase by peptide hydroxamic acids. Biochemistry 1992, 31:7152-7160
30. Porras-Reyes BH, Blair HC, Jeffrey JJ, Mustoe TA: Collagenase production at the border of granulation tissue in a healing wound: macrophage and mesenchymal collagenase production in vivo. Connective Tissue Res 1991, 27:63-71
31. Kurpakus MA, Stock EL, Jones JCR: Analysis of wound healing in an in vitro model: early appearance of laminin and a 125 KD polypeptide during adhesion complex formation. J Cell Sci 1990, 96:651-660
32. Ando H, Twining SS, Yue BYJT, Zhou X, Fini ME, Kaiya T, Higginbotham EJ, Sugar J: MMPs and proteinase inhibitors in the human aqueous humor. Invest Ophthalmol Vis Sci 1993, 4:3541-3548
33. Brown SI, Shinobu A, Weller CA: Prevention of the ulcers of the alkali-burned cornea: preliminary studies with collagenase inhibitors. Arch Ophthalmol 1969, 82: 95-103
34. Dohlman CH: The function of the corneal epithelium in health and disease: the Jonas S. Friedenwald Memorial Lecture. Invest Ophthalmol Vis Sci 1971, 10:376-407
35. Gordon JM, Bauer EA, Eisen AZ: Collagenase in human cornea: immunologic localization. Arch Ophthalmol 1980, 98:341-345
36. Kao WW-Y, Ebert J, Kao CW-C, Covington H, Cintron C: Development of monoclonal antibodies recognizing collagenase from rabbit PMN: the presence of this enzyme in ulcerating cornea. Curr Eye Res 1986, 5:801-815
37. Stahle-Backdahl M, Inoue M, Giudice GJ, Parks WC: 92-kD gelatinase is produced by eosinophils at the site of blister formation in bullous pemphigoid and cleaves the extracellular domain of the 18-kD bullous pemphigoid autoantigen. J Clin Invest 1994, 93:2022-2230
38. Saarialho-Kere UK, Crouch EC, Parks WC: Matrix metalloproteinase matrilysin is constitutively expressed in human exocrine epithelium. J Invest Dermatol 1995, 105:190-196
39. Bazan HEP, Tao Y, Bazan NG: Platelet-activating factor induces collagenase expression in corneal epithelial cells. Proc Natl Acad Sci USA 1993, 90:8678-8682
40. Fini ME, Strissel KJ, Girard MT, West-Mays JA, Rinehart WB: Interleukin 1α mediates collagenase synthesis stimulated by phorbol myristate acetate. J Biol Chem 1994, 269:11291-11298
41. Hasty K, Pourmotabbed T, Goldberg G, Thompson J, Spinella D, Stevens R, Mainardi C: Human neutrophil collagenase: a distinct gene product with homology to other matrix metalloproteinases. J Biol Chem 1990, 265:11421-11424
42. Freije JM, Diaz-ltza I, Balbin M, Sanchez LM, Blasco R, Tolivia J, Lopez-Otin C: Molecular cloning and expression of collagenase-3, a novel human matrix metalloproteinase produced by breast carcinomas. J Biol Chem 1994, 269:16766-16773
43. Henriet P, Rousseau GG, Eeckhout Y: Cloning and sequencing of mouse collagenase cDNA: divergence of mouse and rat collagenases from the other mammalian collagenases. FEBS Lett 1992, 310:175-178
44. Greenberg J (Ed): Inhibition of Matrix Metalloproteinases: Therapeutic Potential. Annals of the New York Academy of Sciences, vol 732
45. Burns FR, Gray RD, Paterson CA: Inhibition of alkali-induced corneal ulceration and perforation by a thiol peptide. Invest Ophthalmol Vis Sci 1990, 31:107-114
46. Schultz GS, Strelow S, Stern GA, Chegini N, Grant MB, Galardy RE, Grobelny D, Rowsey JJ, Stonecipher K, Parmley V, Khaw PT: Treatment of alkali-injured rabbit corneas with a synthetic inhibitor of matrix metalloproteinases. Invest Ophthalmol Vis Sci 1992, 33:3325-3331
47. Falanga V: Chronic wounds: pathophysiologic and experimental considerations. J Invest Dermatol 1993, 100:721-725
48. Grinnell F, Ho C-H, Wysocki A: Degradation of fibronectin and vitronectin in chronic wound fluid: analysis by cell blotting, immunoblotting, and cell adhesion assays. J Invest Dermatol 1992, 98:410-416
49. Wysocki AB, Staiano-Coico L, Grinnell F: Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9. J Invest Dermatol 1993, 101:64-68