Transcutaneous carbon dioxide induces mitochondrial apoptosis and suppresses metastasis of oral squamous cell carcinoma in vivo

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Takeda, Daisuke ^a   Hasegawa, Takumi ^a   Ueha, Takeshi ^b   Imai, Yusuke ^a   Sakakibara, Akiko ^a   Minoda, Masaya ^a   Kawamoto, Teruya ^a   Minamikawa, Tsutomu ^a   Shibuya, Yasuyuki ^a   Akisue, Toshihiro ^a   Sakai, Yoshitada ^a   Kurosaka, Masahiro ^a   Komori, Takahide ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NeoChemir Inc   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; CASPASE 3; CASPASE 9; GELATINASE A; GELATINASE B; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; VASCULOTROPIN; TUMOR PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYPOXIA; IN VIVO STUDY; LYMPH NODE METASTASIS; MALE; METASTASIS INHIBITION; MITOCHONDRION; MOUSE; MOUTH SQUAMOUS CELL CARCINOMA; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; REOXYGENATION; SARCOMA CELL LINE; TUMOR INVASION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CARCINOMA, SQUAMOUS CELL; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION REGULATION; METABOLISM; METASTASIS; MOUTH NEOPLASMS; NUDE MOUSE; PATHOLOGY;

ANIMALS; APOPTOSIS; CARBON DIOXIDE; CARCINOMA, SQUAMOUS CELL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MITOCHONDRIA; MOUTH NEOPLASMS; NEOPLASM METASTASIS; NEOPLASM PROTEINS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84903788569     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0100530     Document Type: Article

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