Quantification of recombinant human erythropoietin by amino acid analysis using isotope dilution liquid chromatography-tandem mass spectrometry

Analytical and Bioanalytical Chemistry

Volumn 406, Issue 18, 2014, Pages 4401-4409

  Yim, Jung Hyuk ^a,b   Yoon, Ina ^c   Yang, Hyo Jin ^a,d   Kim, Sook Kyung ^a   Park, Sang Ryoul ^a   Lee, Yong Moon ^b   Jeong, Ji Seon ^a  

^a Korea Research Institute of Standards and Science   (South Korea)

^b Chungbuk National University   (South Korea)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d University of Science and Technology (UST)   (South Korea)

Author keywords

Amino acid analysis; Erythropoietin; Isotope dilution mass spectrometry (ID MS); Protein quantification; UPLC MS MS

Indexed keywords

DILUTION; HYDROLYSIS; INDUCTIVELY COUPLED PLASMA; ISOTOPES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROTEINS;

AMINO ACID ANALYSIS; ERYTHROPOIETIN (EPO); ISOTOPE DILUTION MASS SPECTROMETRY; PROTEIN QUANTIFICATION; UPLC-MS/MS;

AMINO ACIDS;

AMINO ACID; ERYTHROPOIETIN; RECOMBINANT PROTEIN;

CALIBRATION; HUMAN; HYDROLYSIS; ISOTOPE DILUTION ASSAY; LIQUID CHROMATOGRAPHY; PROCEDURES; REPRODUCIBILITY; TANDEM MASS SPECTROMETRY; ULTRAFILTRATION;

AMINO ACIDS; CALIBRATION; CHROMATOGRAPHY, LIQUID; ERYTHROPOIETIN; HUMANS; HYDROLYSIS; RADIOISOTOPE DILUTION TECHNIQUE; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY; ULTRAFILTRATION;

EID: 84903777799     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-014-7838-0     Document Type: Article

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