Development of a sensitive size exclusion HPLC method with fluorescence detection for the quantitation of recombinant human erythropoietin (r-HuEPO) aggregates

Journal of Pharmaceutical and Biomedical Analysis

Volumn 43, Issue 1, 2007, Pages 213-221

  Gunturi, Srinivas R ^a   Ghobrial, Ibrahim ^a   Sharma, Basant ^a  

^a Pharmaceutical Sciences   (United States)

Author keywords

Aggregates; Erythropoietin; Fluorescence; Quantitation; Size exclusion chromatography

Indexed keywords

2 PROPANOL; BUFFER; DIMER; GLYCINE; OLIGOMER; POLYSORBATE 80; POTASSIUM CHLORIDE; RECOMBINANT ERYTHROPOIETIN; SODIUM CHLORIDE;

ACCURACY; ARTICLE; DRUG FORMULATION; FLUORESCENCE; GEL PERMEATION CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PARTICLE SIZE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; VALIDATION PROCESS;

2-PROPANOL; BUFFERS; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; ERYTHROPOIETIN, RECOMBINANT; HUMANS; INDICATORS AND REAGENTS; REPRODUCIBILITY OF RESULTS; SOLVENTS; SPECTROMETRY, FLUORESCENCE;

EID: 33845295483     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2006.06.006     Document Type: Article

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