P2X1-initiated p38 signalling enhances thromboxane A2-induced platelet secretion and aggregation

Thrombosis and Haemostasis

Volumn 112, Issue 1, 2014, Pages 142-150

  Huang, Zhangsen ^a,b   Liu, Pu ^a   Zhu, Linjing ^b   Li, Nailin ^b   Hu, Hu ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

ATP; p38; Platelets

Indexed keywords

1, 4 DIAMINO 1, 4 BIS (2 AMINOPHENYLTHIO) 2, 3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL) IMIDAZOLE; ADENOSINE DIPHOSPHATE; ALPHA, BETA METHYLENEADENOSINE TRIPHOSPHATE; APYRASE; INDOMETACIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; NF449; PADGEM PROTEIN; PURINERGIC P2X RECEPTOR ANTAGONIST; PURINERGIC P2X1 RECEPTOR; THROMBOXANE A2; UNCLASSIFIED DRUG; 15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4,4,',4'',4'''-(CARBONYLBIS(IMINO-5,1,3-BENZENETRIYLBIS(CARBONYLIMINO)))TETRAKIS(BENZENE-1,3-DISULFONATE); BENZENESULFONIC ACID DERIVATIVE; IMIDAZOLE DERIVATIVE; PYRIDINE DERIVATIVE;

ADULT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE RELEASE REACTION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CELL CULTURE; DEGRANULATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; THROMBOCYTE; YOUNG ADULT;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ADULT; BENZENESULFONATES; BLOOD PLATELETS; CELL DEGRANULATION; CELLS, CULTURED; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IMIDAZOLES; MALE; MAP KINASE SIGNALING SYSTEM; P-SELECTIN; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLATELET AGGREGATION; PURINERGIC P2X RECEPTOR ANTAGONISTS; PYRIDINES; RECEPTORS, PURINERGIC P2X1; THROMBOXANE A2; YOUNG ADULT;

EID: 84903762703     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH13-09-0726     Document Type: Article

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