A pH-responsive drug nanovehicle constructed by reversible attachment of cholesterol to PEGylated poly(l-lysine) via catechol-boronic acid ester formation

Acta Biomaterialia

Volumn 10, Issue 8, 2014, Pages 3686-3695

  Yang, Bin ^a   Lv, Yin ^a   Zhu, Jing Yi ^a   Han, Yun Tao ^a   Jia, Hui Zhen ^a   Chen, Wei Hai ^a   Feng, Jun ^a   Zhang, Xian Zheng ^a   Zhuo, Ren Xi ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

Boronate ester; Cellular uptake; Controlled drug release; pH responsiveness; Self assembly

Indexed keywords

AMINO ACIDS; CELL DEATH; CHLORINE COMPOUNDS; CHOLESTEROL; ESTERS; ETHYLENE; ETHYLENE GLYCOL; FLUORESCENCE MICROSCOPY; LANTHANUM COMPOUNDS; MICELLES; PHENOLS; SELF ASSEMBLY; TARGETED DRUG DELIVERY;

BORONATE ESTERS; CELLULAR UPTAKE; CONTROLLED DRUG RELEASE; DOXORUBICIN; NANO-ASSEMBLIES; NANOCONSTRUCTION; NANOVEHICLES; PH RESPONSIVENESS; POLY(L LYSINE); POLY-L-LYSINE;

CONTROLLED DRUG DELIVERY;

BENZENEBORONIC ACID; CATECHOL; CHOLESTEROL; DOXORUBICIN; MONOMETHOXYPOLY(ETHYLENE GLYCOL) POLY( L LYSINE); POLYLYSINE; UNCLASSIFIED DRUG; BORONIC ACID DERIVATIVE; CATECHOL DERIVATIVE; CROSS LINKING REAGENT; DELAYED RELEASE FORMULATION; DRUG VEHICLE; ESTER; MACROGOL DERIVATIVE; NANOCAPSULE;

ACIDIFICATION; ARTICLE; CELL KILLING; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; INTERNALIZATION; MICELLE; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SUSTAINED DRUG RELEASE; CELL NUCLEUS; CHEMISTRY; DELAYED RELEASE FORMULATION; HELA CELL LINE; METABOLISM; SYNTHESIS; ULTRASTRUCTURE;

BORONIC ACIDS; CATECHOLS; CELL NUCLEUS; CHOLESTEROL; CROSS-LINKING REAGENTS; DELAYED-ACTION PREPARATIONS; DOXORUBICIN; ESTERS; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; NANOCAPSULES; PARTICLE SIZE; PHARMACEUTICAL VEHICLES; POLYETHYLENE GLYCOLS; POLYLYSINE;

EID: 84903740868     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2014.05.018     Document Type: Article

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