Doxorubicin conjugate of poly(ethylene glycol)-block-polyphosphoester for cancer therapy

Advanced Healthcare Materials

Volumn 3, Issue 2, 2014, Pages 261-272

  Sun, Chun Yang ^a   Dou, Shuang ^a   Du, Jin Zhi ^a   Yang, Xian Zhu ^a   Li, Ya Ping ^b   Wang, Jun ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Biodegradable polymers; Cancer therapy; Drug conjugates; Nanomedicine; Polyphosphoesters

Indexed keywords

BIOCOMPATIBILITY; BIODEGRADABLE POLYMERS; CELLS; DISEASES; ETHYLENE GLYCOL; MAMMALS; MEDICAL NANOTECHNOLOGY; NANOPARTICLES; ONCOLOGY; POLYETHYLENE GLYCOLS; POLYOLS; SYNTHESIS (CHEMICAL); TARGETED DRUG DELIVERY; TUMORS;

ANTI-PROLIFERATIVE ACTIVITIES; CANCER THERAPY; CONTROLLED SYNTHESIS; DOXORUBICIN CONJUGATES; DRUG-CONJUGATES; INHIBITION OF TUMOR GROWTH; POLYPHOSPHOESTERS; SPHERICAL NANOPARTICLES;

CONTROLLED DRUG DELIVERY;

DOXORUBICIN; DOXORUBICIN DERIVATIVE; POLY(ETHYLENE GLYCOL) BLOCK POLYPHOSPHOESTER DOXORUBICIN CONJUGATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; AQUEOUS SOLUTION; AREA UNDER THE CURVE; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CHEMOTHERAPY; CANCER INHIBITION; CELL PH; CHEMICAL BOND; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG RELEASE; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TOLERABILITY; DRUG TUMOR LEVEL; ENDOSOME; FEMALE; HUMAN; HUMAN CELL; HYDRAZONE BOND; IN VITRO STUDY; INTERNALIZATION; LYSOSOME; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; TUMOR XENOGRAFT;

BIODEGRADABLE POLYMERS; CANCER THERAPY; DRUG CONJUGATES; NANOMEDICINE; POLYPHOSPHOESTERS;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; DOXORUBICIN; DRUG DELIVERY SYSTEMS; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; POLYETHYLENE GLYCOLS; POLYMERS;

EID: 84893454622     PISSN: 21922640     EISSN: 21922659     Source Type: Journal    
DOI: 10.1002/adhm.201300091     Document Type: Article

References (65)

1. a) C. Li, S. Wallace, Adv. Drug Deliv. Rev. 2008, 60, 886
2. b) A. Kamb, Nat. Rev. Drug Discov. 2005, 4, 161.
3. a) Y. Matsumura, H. Maeda, Cancer Res. 1986, 46, 6387
4. b) H. Maeda, J. Wu, T. Sawa, Y. Matsumura, K. Hori, J. Controlled Release 2000, 65, 271.
5. a) R. Duncan, Nat. Rev. Cancer 2006, 6, 688
6. b) D. Peer, J. M. Karp, S. Hong, O. C. FaroKhzad, R. Margalit, R. Langer, Nat. Nanotechnol. 2007, 2, 751
7. c) E. V. Batrakova, S. Li, A. M. Brynskikh, A. K. Sharma, Y. L. Li, M. Boska, N. Gong, R. L. Mosley, V. Y. Alakhov, H. E. Gendelman, A. V. Kabanov, J. Controlled Release 2010, 143, 290.
8. a) T. Hamaguchi, Y. Matsumura, M. Suzuki, K. Shimizu, R. Goda, I. Nakamura, I. Nakatomi, M. Yokoyama, K. Kataoka, T. Kakizoe, Br. J. Cancer 2005, 92, 1240
9. b) T. Negishi, F. Koizumi, H. Uchino, J. Kuroda, T. Kawaguchi, S. Naito, Y. Matsumura, Br. J. Cancer 2006, 95, 601.
10. a) J. A. MacKay, M. Chen, J. R. McDaniel, W. Liu, A. J. Simnick, A. Chilkoti, Nat. Mater. 2009, 8, 993
11. b) Y. Barenholz, J. Controlled Release 2012, 160, 117.
12. N. Larson, H. Ghandehari, Chem. Mater. 2012, 24, 840.
13. a) M. Calderon, P. Welker, K. Licha, I. Fichtner, R. Graeser, R. Haag, F. Kratz, J. Controlled Release 2011, 151, 295
14. b) L. Zhou, R. Cheng, H. Tao, S. Ma, W. Guo, F. Meng, H. Liu, Z. Liu, Z. Zhong, Biomacromolecules 2011, 12, 1460.
15. a) L. Liang, S. W. Lin, W. B. Dai, J. K. Lu, T. Y. Yang, Y. Xiang, Y. Zhang, R. T. Li, Q. Zhang, J. Controlled Release 2012, 160, 618
16. b) S. Ibsen, E. Zahavy, W. Wrasdilo, M. Berns, M. Chan, S. Esener, Pharm. Res. 2010, 27, 1848
17. c) S. O. Doronina, B. E. Toki, M. Y. Torgov, B. A. Mendelsohn, C. G. Cerveny, D. F. Chace, R. L. DeBlanc, R. P. Gearing, T. D. Bovee, C. B. Siegall, J. A. Francisco, A. F. Wahl, D. L. Meyer, P. D. Senter, Nat. Biotechnol. 2003, 21, 941.
18. a) D. Bissett, J. Cassidy, J. S. de Bono, F. Muirhead, M. Main, L. Robson, D. Fraier, M. L. Magne, C. Pellizzoni, M. G. Porro, R. Spinelli, W. Speed, C. Twelves, Br. J. Cancer 2004, 91, 50
19. b) L. W. Seymour, D. R. Ferry, D. Anderson, S. Hesslewood, P. J. Julyan, R. Poyner, J. Doran, A. M. Young, S. Burtles, D. J. Kerr, C. R. C. P. I.-I. Clin, J. Clin. Oncol. 2002, 20, 1668
20. c) A. Malugin, P. Kopeckova, J. Kopecek, J. Controlled Release 2007, 124, 6.
21. a) W. B. Liechty, D. R. Kryscio, B. V. Slaughter, N. A. Peppas, Annu. Rev. Chem. Biomol. Eng. 2010, 1, 149
22. b) M. Elsabahy, K. L. Wooley, Chem. Soc. Rev. 2012, 41, 2545.
23. a) S. E. Gratton, P. A. Ropp, P. D. Pohlhaus, J. C. Luft, V. J. Madden, M. E. Napier, J. M. DeSimone, Proc. Natl. Acad. Sci. USA 2008, 105, 11613
24. b) D. S. Lin, Y. Y. Huang, Q. Jiang, W. D. Zhang, X. Y. Yue, S. T. Guo, P. Xiao, Q. Du, J. F. Xing, L. D. Deng, Z. C. Liang, A. J. Dong, Biomaterials 2011, 32, 8730
25. c) T. Etrych, L. Kovar, J. Strohalm, P. Chytil, B. Rihova, K. Ulbrich, J. Controlled Release 2011, 154, 241
26. d) H. Cabral, Y. Matsumoto, K. Mizuno, Q. Chen, M. Murakami, M. Kimura, Y. Terada, M. R. Kano, K. Miyazono, M. Uesaka, N. Nishiyama, K. Kataoka, Nat. Nanotechnol. 2011, 6, 815
27. e) M. N. Holme, I. A. Fedotenko, D. Abegg, J. Althaus, L. Babel, F. Favarger, R. Reiter, R. Tanasescu, P.L. Zaffalon, A. Ziegler, B. Mueller, T. Saxer, A. Zumbuehl, Nat. Nanotechnol. 2012, 7, 536
28. f) X. Jiang, W. Qu, D. Pan, Y. Ren, J. M. Williford, H. Cui, E. Luijten, H. Q. Mao, Adv. Mater. 2013, 25, 227.
29. Y. C. Wang, Y. Y. Yuan, J. Z. Du, X. Z. Yang, J. Wang, Macromol. Biosci. 2009, 9, 1154.
30. a) Y. C. Wang, L. Y. Tang, T. M. Sun, C.H. Li, M. H. Xiong, J. Wang, Biomacromolecules 2008, 9, 388
31. b) X. Z. Yang, Y. C. Wang, L. Y. Tang, H. Xia, J. Wang, J. Polym. Sci., Part A: Polym. Chem. 2008, 46, 6425.
32. a) Y. Iwasaki, E. Yamaguchi, Macromolecules 2011, 43, 2664
33. b) C. S. Xiao, Y. C. Wang, J. Z. Du, X. S. Chen, J. Wang, Macromolecules 2006, 39, 6825
34. c) Y. C. Wang, S. Y. Shen, Q. P. Wu, D. P. Chen, J. Wang, G. Steinhoff, N. Ma, Macromolecules 2006, 39, 8992
35. a) S. Zhang, A. Li, J. Zou, L. Y. Lin, K. L. Wooley, ACS Macro Lett. 2012, 1, 328
36. b) S. Y. Zhang, J. Zou, F. W. Zhang, M. Elsabahy, S. E. Felder, J. H. Zhu, D. J. Pochan, K. L. Wooley, J. Am. Chem. Soc. 2012, 134, 18467
37. c) B. Clement, B. Grignard, L. Koole, C. Jerome, P. Lecomte, Macromolecules 2012, 45, 4476.
38. J. Z. Du, X. J. Du, C. Q. Mao, J. Wang, J. Am. Chem. Soc. 2011, 133, 17560.
39. Y. Y. Yuan, C. Q. Mao, X. J. Du, J. Z. Du, F. Wang, J. Wang, Adv. Mater. 2012, 24, 5476.
40. Z. Z. Lu, J. Wu, T. M. Sun, J. Ji, L. F. Yan, J. Wang, Biomaterials 2008, 29, 733.
41. a) X. Z. Yang, J. Z. Du, S. Dou, C. Q. Mao, H. Y. Long, J. Wang, ACS Nano 2012, 6, 771
42. b) T. M. Sun, J. Z. Du, Y. D. Yao, C. Q. Mao, S. Dou, S. Y. Huang, P. Z. Zhang, K. W. Leong, E. W. Song, J. Wang, Acs Nano 2011, 5, 1483
43. c) C. Q. Mao, J. Z. Du, T. M. Sun, Y. D. Yao, P. Z. Zhang, E. W. Song, J. Wang, Biomaterials 2011, 32, 3124.
44. X. Z. Yang, T. M. Sun, S. Dou, J. Wu, Y. C. Wang, J. Wang, Biomacromolecules 2009, 10, 2213.
45. A. Rosler, G. W. M. Vandermeulen, H. A. Klok, Adv. Drug Delivery Rev. 2001, 53, 95.
46. W. She, K. Luo, C. Zhang, G. Wang, Y. Geng, L. Li, B. He, Z. Gu, Biomaterials 2013, 34, 1613.
47. M. K. Kiesewetter, E. J. Shin, J. L. Hedrick, R. M. Waymouth, Macromolecules 2010, 43, 2093.
48. Y. Bae, S. Fukushima, A. Harada, K. Kataoka, Angew. Chem. Int. Ed. 2003, 42, 4640.
49. R. Tong, J. J. Cheng, Bioconjug. Chem. 2010, 21, 111.
50. M. E. Davis, Z. Chen, D. M. Shin, Nat. Rev. Drug Discov. 2008, 7, 771.
51. I. F. Tannock, D. Rotin, Cancer Res. 1989, 49, 4373.
52. W. She, N. Li, K. Luo, C. Guo, G. Wang, Y. Geng, Z. Gu, Biomaterials 2013, 34, 2252.
53. a) L. Zhu, P. Kate, V. P. Torchilin, ACS Nano 2012, 6, 3491
54. b) E. S. Lee, Z. Gao, D. Kim, K. Park, I. C. Kwon, Y. H. Bae, J. Controlled Release 2008, 129, 228.
55. F. Wang, Y. C. Wang, L. F. Yan, J. Wang, Polymer 2009, 50, 5048.
56. a) K. M. Tewey, T. C. Rowe, L. Yang, B. D. Halligan, L. F. Liu, Science 1984, 226, 466
57. b) D. A. Gewirtz, Biochem. Pharmacol. 1999, 57, 727.
58. Y. Wu, S. Ihme, M. Feuring-Buske, S. L. Kuan, K. Eisele, M. Lamla, Y. Wang, C. Buske, T. Weil, Adv. Healthcare Mater., DOi: 10.1002/adhm.201200296
59. Z. Liu, A. C. Fan, K. Rakhra, S. Sherlock, A. Goodwin, X. Y. Chen, Q. W. Yang, D. W. Felsher, H. J. Dai, Angew. Chem. Int. Ed. 2009, 48, 7668.
60. a) Y. C. Wang, X. Q. Liu, T. M. Sun, M. H. Xiong, J. Wang, J. Controlled Release 2008, 128, 32
61. b) P. C. Zhang, L. J. Hu, Y. C. Wang, J. Wang, L. Y. Feng, Y. P. Li, Pharm. Res. 2010, 27, 2657
62. c) G. S. Kwon, M. Yokoyama, T. Okano, Y. Sakurai, K. Kataoka, Pharm. Res. 1993, 10, 970.
63. S. E. Lipshultz, M. A. Grenier, S. D. Colan, N. Engl. J. Med 1999, 340, 653.
64. M. von Delius, E. M. Geertsema, D. A. Leigh, D.-T. D. Tang, J. Am. Chem. Soc. 2010, 132, 16134.
65. F. Wang, Y. C. Wang, S. Dou, M. H. Xiong, T. M. Sun, J. Wang, ACS Nano 2011, 5, 3679.