New whole-body multimodality imaging of gastric cancer peritoneal metastasis combining fluorescence imaging with ICG-labeled antibody and MRI in mice

Gastric Cancer

Volumn 17, Issue 3, 2014, Pages 497-507

  Ito, Akihiro ^a,b   Ito, Yuichi ^a   Matsushima, Shigeru ^a   Tsuchida, Daisuke ^b   Ogasawara, Mai ^b   Hasegawa, Junichi ^c   Misawa, Kazunari ^a   Kondo, Eisaku ^a   Kaneda, Norio ^b   Nakanishi, Hayao ^a  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b MEIJO UNIVERSITY   (Japan)

^c CHUKYO UNIVERSITY   (Japan)

Author keywords

CEA; Cetuximab; Fluorescence imaging; Gastric cancer; ICG; Molecular imaging; MRI; Multimodality imaging; NIR fluorophore; Peritoneal metastasis

Indexed keywords

CARCINOEMBRYONIC ANTIBODY; CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; FLUORESCENT DYE; INDOCYANINE GREEN; LUCIFERASE; RITUXIMAB; UNCLASSIFIED DRUG; XENOLIGHT CF 750; CARCINOEMBRYONIC ANTIGEN; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY LABELING; ARTICLE; CANCER SIZE; CLINICAL ARTICLE; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; DRUG DISTRIBUTION; FLUORESCENCE IMAGING; GASTRIC CANCER CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMAGE ANALYSIS; IMAGING SYSTEM; IN VIVO STUDY; INTERMETHOD COMPARISON; MALE; MOLECULAR PROBE; MOUSE; NEAR INFRARED FLUOROPHORE; NON INVASIVE MEASUREMENT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; ORGAN DISTRIBUTION; PERITONEAL CAVITY; PERITONEUM METASTASIS; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SIGNAL DETECTION; STOMACH CANCER; THREE DIMENSIONAL IMAGING; WHOLE BODY IMAGING; ANIMAL; CANCER STAGING; COMPARATIVE STUDY; DIAGNOSTIC USE; IMMUNOLOGY; NUDE MOUSE; PATHOLOGY; PERITONEAL NEOPLASMS; PROCEDURES; SECONDARY; STOMACH TUMOR;

ANIMALS; ANTIBODIES, MONOCLONAL; CARCINOEMBRYONIC ANTIGEN; HUMANS; IMAGING, THREE-DIMENSIONAL; INDOCYANINE GREEN; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, NUDE; NEOPLASM STAGING; OPTICAL IMAGING; PERITONEAL NEOPLASMS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SENSITIVITY AND SPECIFICITY; STOMACH NEOPLASMS;

EID: 84903730561     PISSN: 14363291     EISSN: 14363305     Source Type: Journal    
DOI: 10.1007/s10120-013-0316-0     Document Type: Article

References (29)

1. Moriguchi S, Maehara Y, Korenaga D, Sugimachi K, Nose Y. Risk factors which predict pattern of recurrence after curative surgery for patients with advanced gastric cancer. Surg Oncol. 1992;1(5):341-6.
2. Sugarbaker PH, Yonemura Y. Clinical pathway for the management of resectable gastric cancer with peritoneal seeding: best palliation with a ray of hope for cure. Oncology. 2000; 58(2):96-107.
3. Kim SJ, Kim HH, Kim YH, Hwang SH, Lee HS, do Park J, et al. Peritoneal metastasis: detection with 16- or 64-detector row CT in patients undergoing surgery for gastric cancer. Radiology. 2009;253(2):407-15.
4. Magota K, Kubo N, Kuge Y, Nishijima K, Zhao S, Tamaki N. Performance characterization of the Inveon preclinical small-animal PET/SPECT/CT system for multimodality imaging. Eur J Nucl Med Mol Imaging. 2011;38(4):742-52.
5. Turlakow A, Yeung HW, Salmon AS, Macapinlac HA, Larson SM. Peritoneal carcinomatosis: role of 18F-FDG PET. J Nucl Med. 2003;44(9):1407-12.
6. Xu H, Eck PK, Baidoo KE, Choyke PL, Brechbiel MW. Toward preparation of antibody-based imaging probe libraries for dual-modality positron emission tomography and fluorescence imaging. Bioorg Med Chem. 2009;17(14):5176-81.
7. Massoud TF, Gambhir SS. Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev. 2003;17(5):545-80 (Review).
8. Nakanishi H, Mochizuki Y, Kodera Y, Ito S, Yamamura Y, Ito K, et al. Chemosensitivity of peritoneal micrometastases as evaluated using a green fluorescence protein (GFP)-tagged human gastric cancer cell line. Cancer Sci. 2003;94(1):112-8.
9. Yanagihara K, Takigahira M, Takeshita F, Komatsu T, Nishio K, Hasegawa F, et al. A photon counting technique for quantitatively evaluating progression of peritoneal tumor dissemination. Cancer Res. 2006;66:7532-9.
10. Hoffman RM. Green fluorescent protein imaging of tumour growth, metastasis, and angiogenesis in mouse models. Lancet Oncol. 2002;3(9):546-56.
11. McCann TE, Kosaka N, Turkbey B, Mitsunaga M, Choyke PL, Kobayashi H. Molecular imaging of tumor invasion and metastases: the role of MRI. NMR Biomed. 2011;24(6):561-8.
12. Nolting DD, Gore JC, Pham W. Near-infrared dyes: probe development and applications in optical molecular imaging. Curr Org Synth. 2011;8(4):521-34.
13. Koyama Y, Barrett T, Hama Y, Ravizzini G, Choyke PL, Kobayashi H. In vivo molecular imaging to diagnose and subtype tumors through receptor-targeted optically labeled monoclonal antibodies. Neoplasia. 2007;9:1021-9.
14. Yasumoto K, Yamada T, Kawashima A, Wang W, Li Q, Donev IS, et al. The EGFR ligands amphiregulin and heparin-binding egf-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer. Clin Cancer Res. 2011; 17(11):3619-30.
15. Schlessinger J. Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell. 2002;110:669-72.
16. Tokunaga A, Onda M, Okuda T, Teramoto T, Fujita I, Mizutani T, et al. Clinical significance of epidermal growth factor (EGF), EGF receptor, and c-erbB-2 in human gastric cancer. Cancer (Phila). 1995;75:1418-25.
17. Galizia G, Lieto E, De Vita F, Orditura M, Castellano P, Troiani T, et al. Cetuximab, a chimeric human mouse anti-epidermal growth factor receptor monoclonal antibody, in the treatment of human colorectal cancer. Oncogene. 2007;26:3654-60.
18. Hara M, Nakanishi H, Tsujimura K, Matsui M, Yatabe Y, Manabe T, et al. Interleukin-2 potentiation of cetuximab antitumor activity for epidermal growth factor receptor-overexpressing gastric cancer xenografts through antibody-dependent cellular cytotoxicity. Cancer Sci. 2008;99:1471-8.
19. Pinto C, Di Fabio F, Siena S, Cascinu S, Rojas Llimpe FL, Ceccarelli C, et al. Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study). Ann Oncol. 2007;18:510-7.
20. Nakanishi H, Kodera Y, Yamamura Y, Ito S, Kato T, Ezaki T, et al. Rapid quantitative detection of carcinoembryonic antigen-expressing free tumor cells in the peritoneal cavity of gastric cancer patients. Int J Cancer. 2000;89:411-7.
21. United Kingdom Co-Ordinating Committee on Cancer Research (UKCCCR) Guidelines for the Welfare of Animals in Experimental Neoplasia, 2nd edn. Br J Cancer 1998; 77:1-10.
22. Nakanishi H, Yasui K, Ikehara Y, Yokoyama H, Munesue S, Kodera Y, Tatematsu M. Establishment and characterization of three novel human gastric cancer cell lines with differentiated intestinal phenotype derived from liver metastasis. Clin Exp Metastasis. 2005;22:137-47.
23. Barrett T, Koyama Y, Hama Y, Ravizzini G, Shin IS, Jang BS, Paik CH, Urano Y, Choyke PL, Kobayashi H. In vivo diagnosis of epidermal growth factor receptor expression using molecular imaging with a cocktail of optically labeled monoclonal antibodies. Clin Cancer Res. 2007;13:6639-48.
24. Rosenthal EL, Kulbersh BD, King T, Chaudhuri TR, Zinn KR. Use of fluorescent labeled anti-epidermal growth factor receptor antibody to image head and neck squamous cell carcinoma xenografts. Mol Cancer Ther. 2007;6(4):1230-8.
25. Kramer-Marek G, Longmire MR, Choyke PL, Kobayashi H. Recent advances in optical cancer imaging of EGF receptors. Curr Med Chem. 2012;19(28):4759-66.
26. Nayak TK, Regino CA, Wong KJ, Milenic DE, Garmestani K, Baidoo KE, et al. PET imaging of HER1-expressing xenografts in mice with 86Y-CHX-A"-DTPA- cetuximab. Eur J Nucl Med Mol Imaging. 2010;37:1368-76.
27. Niu G, Sun X, Cao Q, Courter D, Koong A, Le QT, et al. Cetuximab-based immunotherapy and radioimmunotherapy of head and neck squamous cell carcinoma. Clin Cancer Res. 2010; 16:2095-105.
28. Manning HC, Merchant NB, Foutch AC, Virostko JM, Wyatt SK, Shah C, et al. Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer. Clin Cancer Res. 2008;14:7413-22.
29. Mitsunaga M, Tajiri H, Choyke PL, Kobayashi H. Monoclonal antibody-fluorescent probe conjugates for in vivo target-specific cancer imaging: toward clinical translation. Ther Deliv. 2013; 4(5):523-5.