Chemosensitivity of peritoneal micrometastases as evaluated using a green fluorescence protein (GFP)-tagged human gastric cancer cell line

Cancer Science

Volumn 94, Issue 1, 2003, Pages 112-118

  Nakanishi, Hayao ^a   Mochizuki, Yoshinari ^a   Kodera, Yasuhiro ^b   Ito, Seiji ^a   Yamamura, Yoshitaka ^a   Ito, Katsuki ^b   Akiyama, Seiji ^b   Nakao, Akimasa ^b   Tatematsu, Masae ^a  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5 CHLORO 2,4 DIHYDROXYPYRIDINE PLUS OXONATE POTASSIUM PLUS TEGAFUR; ANTINEOPLASTIC AGENT; FLUOROPYRIMIDINE DERIVATIVE; FLUOROURACIL; GREEN FLUORESCENT PROTEIN; TS 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASCITES; CANCER CELL CULTURE; CANCER STAGING; CANCER SURVIVAL; CANCER SUSCEPTIBILITY; CHEMOSENSITIVITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ILLUMINATION; MALE; MESENTERY; MOUSE; NONHUMAN; NUDE MOUSE; OMENTUM; PERITONEAL CAVITY; PERITONEUM METASTASIS; PRIORITY JOURNAL; QUALITY OF LIFE; STOMACH CANCER; TUMOR CELL;

ADMINISTRATION, ORAL; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; ASCITES; CARCINOMA; CELL COUNT; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HUMANS; INJECTIONS, INTRAPERITONEAL; LUMINESCENT PROTEINS; MALE; MESENTERY; MICE; MICE, NUDE; OMENTUM; OXONIC ACID; PERITONEAL NEOPLASMS; PRODRUGS; PYRIDINES; STOMACH NEOPLASMS; TEGAFUR; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0038324268     PISSN: 13479032     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2003.tb01361.x     Document Type: Article

References (40)

1. Averbach AM, Jacquet P. Strategies to decrease the incidence of intra-abdominal recurrence in resectable gastric cancer. Br J Surg 1996; 83: 726-33.
2. Moriguchi S, Maehara Y, Korenaga D, Sugimachi K, Nose Y. Risk factors which predict pattern of recurrence after curative surgery for patients with advanced gastric cancer. Surg Oncol 1992; 1: 341-6.
3. Yonemura Y, Fujimura T, Nishimura G. Falla R, Sawa T, Katayama K, Tsugawa K, Fushida S, Miyazaki I, Tanaka M, Endou Y, Sasaki T. Effects of intraoperative chemohyperthermia in patients with gastric cancer with peritoneal dissemination. Surgery 1996; 119: 437-44.
4. Rosen HR, Jatzko G, Repse S, Potrc S, Neudorfer H, Sandbichler P, Zacherl J, Rabl H, Holzberger P, Lisborg P, Czeijka, M. Adjuvant intraperitoneal chemotherapy with carbon-absorbed mitomycin in patients with gastric cancer. J Clin Oncol 1998; 16: 2733-8.
5. Sautner T, Hofbauer F, Depisch D, Schiessel R, Jakesz R. Adjuvant intraperitoneal cisplatin chemotherapy does not improve long-term survival after surgery for advanced gastric cancer. J Clin Oncol 1994; 12: 970-4.
6. Nakanishi H, Kobayashi K, Nishimura T, Inada K, Tsukamoto T, Tatematsu M. Chemosensitivity, of micrometastases and circulating tumor cells to uracil and tegafur as evaluated using LacZ gene-tagged Lewis lung carcinoma cell. Cancer Lett 1999; 142: 31-41.
7. Kurebayashi J, Nukatsuka M, Fujioka A, Saito H, Takeda S, Unemi N, Fukumori H, Kurosumi M, Sonoo H, Dickson RB. Postsurgical oral administration of uracil and tegafur inhibits progression of micrometastasis of human breast cancer cells in nude mice. Clin Cancer Res 1997; 3: 653-9.
8. Nakanishi H, Kodera Y, Torii A, Hirai T, Yamamura Y, Kato T, Kito T, Tatematsu M. Detection of carcinoembryonic antigen-expressing free tumor cells in peritoneal washes from patients with gastric carcinoma by polymerase chain reaction. Jpn J Cancer Res 1997; 88: 687-92.
9. Yonemura Y, Fujimura T, Ninomiya I, Kim BS, Bandou E, Sawa T, Kinoshita K, Endo Y, Sugiyama K, Sasaki T. Prediction of peritoneal micrometastasis by peritoneal lavaged cytology and reverse transcriptase-polymerase chain reaction for matrix metalloproteinase-7 mRNA. Clin Cancer Res 2001; 7: 1647-53.
10. Nakanishi H, Kodera Y, Yamamura Y, Ito S, Kato T, Ezaki T, Tatematsu M. Rapid quantitative detection of carcinoembryonic antigen-expressing free tumor cells in the peritoneal cavity of gastric-cancer patients with real-time RT-PCR on the light cycler. Int J Cancer 2000; 89: 411-7.
11. Kodera Y, Nakanishi H, Yamamura Y, Shimizu Y, Torii A, Hirai T, Yasui K, Morimoto T, Kato T, Kito T, Tatematsu M. Prognostic value and clinical implications of disseminated cancer cells in the peritoneal cavity detected by reverse transcriptase-polymerase chain reaction and cytology. Int J Cancer 1998; 79: 426-33.
12. Kodera Y, Nakanishi H, Ito S, Yamamura Y, Kanemitsu Y, Shimizu Y, Hirai T, Yasui K, Kato T, Tatematsu M. Quantitative detection of disseminated free cancer cells in peritoneal washes with real-time reverse transcriptase-polymerase chain reaction: a sensitive predictor of outcome for patients with gastric carcinoma. Ann Surg 2002; 235: 499-506.
13. Lin WC, Pretlow TP, Pretlow TGD, Culp LA. Development of micrometastases: earliest events detected with bacterial LacZ gene-tagged tumor cells. J Natl Cancer Inst 1990; 82: 1497-1503.
14. Morin JG, Hastings JW. Energy transfer in a bioluminescent system. J Cell Physiol 1971; 77: 313-8.
15. Misteli T, Spector DL. Applications of the green fluorescent protein in cell biology and biotechnology. Nat Biotechnol 1997; 15: 961-4.
16. Chishima T, Miyagi Y, Wang X, Yamaoka H, Shimada H, Moossa AR, Hoffman RM. Cancer invasion and micrometastasis visualized in live tissue by green fluorescent protein expression. Cancer Res 1997; 57: 2042-7.
17. Hoffman RM. Orthotopic transplant mouse models with green fluorescent protein-expressing cancer cells to visualize metastasis and angiogenesis. Cancer Metastasis Rev 1999; 17: 271-7.
18. Ito S, Nakanishi H, Ikehara Y, Kato T, Kasai Y, Ito K, Akiyama S, Nakao A, Tatematsu M. Real-time observation of micrometastasis formation in the living mouse liver using a green fluorescent protein gene-tagged rat tongue carcinoma cell line. Int J Cancer 2001; 91: 212-7.
19. Bouvet M, Wang J, Nardin SR, Nassirpour R, Yang M, Baranov E, Jiang P, Moossa AR, Hoffman RM. Real-time optical imaging of primary tumor growth and multiple metastatic events in pancreatic cancer orthotopic model. Cancer Res 2002; 62: 1534-40.
20. Hoffman RM. Orthotopic metastatic mouse models for anticancer drug discovery and evaluation: a bridge to the clinic. Invest New Drugs 1999; 17: 343-59.
21. Hoffman RM. Green fluorescent protein imaging of tumour growth, metastasis, and angiogenesis in mouse models. Lancet Oncol 2002; 3: 546-56.
22. Chaudhuri TR, Mountz JM, Rogers BE, Partridge EE, Zinn KR. Light-based imaging of green fluorescent protein-positive ovarian cancer xenografts during therapy. Gynecol Oncol 2001; 82: 581-9.
23. Shirasaka T, Nakano K, Takechi T, Satake H, Uchida J, Fujioka A, Saito H, Okabe H, Oyama K, Takeda S, Unemi N, Fukushima M. Antitumor activity of 1 M tegafur-0.4 M 5-chloro-2,4-dihydroxypridine-1 M potassium oxonate (S-1) against human colon carcinoma orthotopically implanted into nude rats. Cancer Res 1996; 56: 2602-6.
24. Shirasaka T, Shimamoto Y, Ohshimo H, Yamaguchi M, Kato T, Yonekura K, Fukushima M. Development of a novel form of an oral 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators. Anticancer Drugs 1995; 7: 548-57.
25. Osugi H, Takada N, Takemura M, Kaseno S, Lee S, Ueno M, Tanaka Y, Fukuhara K, Fujiwara Y, Kinoshita H. Oral fluoropyrimidine anticancer drugs TS-1 for gastric cancer patients with peritoneal dissemination. Oncol Rep 2002; 9: 811-5.
26. Nozue M, Nishida M, Todoroki T, Iwasaki Y. Establishment and characterization of a human scirrhous type gastric cancer cell line, GCIY, producing CA19-9. Hum Cell 1991; 4: 71-5 (in Japanese).
27. Cormack BP, Valdivia RH, Falkow S. FACS-optimized mutants of the green fluorescent protein (GFP). Gene 1996; 173: 33-8.
28. Yang M, Chishima. T, Wang X, Baranov E, Shimada H, Moossa AR, Hoffman RM. Multi-organ metastatic capability of Chinese hamster ovary cells revealed by green fluorescent protein (GFP) expression. Clin Exp Metastasis 1999; 17: 417-22.
29. Kaneko K, Yano M, Tsujinaka T, Morita S, Taniguchi M, Fujiwara Y, Doki Y, Inoue M, Shiozaki H, Monden A Establishment of a visible peritoneal micrometastatic model from a gastric adenocarcinoma cell line by green fluorescent protein. Int J Oncol 2000; 16: 893-8.
30. Hasegawa S, Yang M, Chishima T, Miyagi Y, Shimada H, Moossa AR, Hoffman RM. In vivo tumor delivery of the green fluorescent protein gene to report future occurrence of metastasis. Cancer Gene Ther 2000; 7: 1336-40.
31. Kamiyama M, Ichikawa Y, Chishima T, Hasegawa S, Hamaguchi Y, Nagashima Y, Miyagi Y, Mitsuhashi M, Hyndman D, Hoffman RM, Ohki S, Shimada H. VEGF receptor antisense therapy inhibits angiogenesis and peritoneal dissemination of human gastric cancer in nude mice. Cancer Gene Ther 2002; 2: 197-201.
32. Ishikawa T, Ura M, Yamamoto T, Tanaka Y, Ishitsuka H. Selective inhibition of spontaneous pulmonary metastasis of Lewis lung carcinoma by 5′-deoxy-5-fluorouridine. Int J Cancer 1995; 61: 516-21.
33. Nakanishi H, Abe A, Inada K, Tsukamoto T, Yasui K, Tatematsu M. Induction of apoptosis in metastatic foci from human gastric cancer xenografts in nude mice and reduction of circulating tumor cells in blood by 5-FU and 1-hexylcarbamoyl-5-fluorouracil. J Cancer Res Clin Oncol 1999; 125: 660-8.
34. Sugamura K, Makino M, Shirai H, Kimura O, Maeta M, Itoh H, Kaibara N. Enhanced induction of apoptosis of human gastric carcinoma cells after preoperative treatment with 5-fluorouracil. Cancer 1997; 79: 12-7.
35. Ozols RF, Locker GY, Doroshow JH, Grotzinger KR, Myers CE, Young RC. Pharmacokinetics of adriamycin and tissue penetration in murine ovarian cancer. Cancer Res 1979; 39: 3209-14.
36. Maeda K, Chung YS, Ogawa Y, Takatsuka. S, Kang SM, Ogawa M, Sawada T, Onoda N, Kato Y, Sowa M. Thymidine phosphorylase/platelet-derived endothelial cell growth factor expression associated with hepatic metastasis in gastric carcinoma. Br J Cancer 1996; 73: 884-8.
37. Folkman J, Klagsbrun M. Angiogenetic factors. Science 1987; 234: 442-7.
38. Matsuura T, Fukuda Y, Fujitaka T, Nishisaka T, Sakatani T, Ito H. Preoperative treatment with tegafur suppositories enhances apoptosis and reduces the intratumoral microvessel density of human colorectal carcinoma. Cancer 2000; 88: 1007-15.
39. Copur S, Aiba K, Drake JC, Allegra CJ, Chu E. Thymidylate synthase gene amplification in human colon cancer cell lines resistant to 5-fluorouracil. Biochem Pharmacol 1992; 49: 1419-26.
40. Takahashi Y, Nishioka K. Survival without tumor shrinkage: re-evaluation of survival gain by cytostatic effect of chemotherapy. J Natl Cancer Inst 1995; 87: 1262-3.